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The map label for this gene is hupB [H]

Identifier: 118581076

GI number: 118581076

Start: 2900458

End: 2900733

Strand: Direct

Name: hupB [H]

Synonym: Ppro_2665

Alternate gene names: 118581076

Gene position: 2900458-2900733 (Clockwise)

Preceding gene: 118581075

Following gene: 118581077

Centisome position: 72.37

GC content: 55.8

Gene sequence:

>276_bases
ATGACAAAAGCAGAGCTTGTAGCAAGAATGGCAGAGAGCGGCGACATCACCAAAGCCGCGGCGGAAAAAGCTCTTGGTGG
CTTCATTGAAGCGGTGACAGAAGCGATCAAGGCCGGCGAAAAAGTGACGCTTACCGGTTTCGGCACCTTCAGCGCAGTTA
CACGGGCTGCCAGGATCGGCCGCAACCCTGCCACAGGTCAGGAACTGCAGATTGCGGCAAAGACATCCGCCAAATTCAGC
CCGGGCAAGGAACTGAAAGACCTGGGCCAGAAATAA

Upstream 100 bases:

>100_bases
CTTCCCGTCCGCAGTCCGATGAGGCGTGATCACAAGTTTGTCTTGTAGCGCCCGATTGTTATGCGGTATAAAACAGCTAA
ATCTCAACACTGGAGGAATC

Downstream 100 bases:

>100_bases
CTCCCTCGGACCGGGGGCCGAGTAAGGCCCCCCGTTTCTTTCAGTCAACACGGCACAGAGCCCTCCCGACACCCACTATC
CAGGCCTCACTCACGACCCT

Product: histone family protein DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 91; Mature: 90

Protein sequence:

>91_residues
MTKAELVARMAESGDITKAAAEKALGGFIEAVTEAIKAGEKVTLTGFGTFSAVTRAARIGRNPATGQELQIAAKTSAKFS
PGKELKDLGQK

Sequences:

>Translated_91_residues
MTKAELVARMAESGDITKAAAEKALGGFIEAVTEAIKAGEKVTLTGFGTFSAVTRAARIGRNPATGQELQIAAKTSAKFS
PGKELKDLGQK
>Mature_90_residues
TKAELVARMAESGDITKAAAEKALGGFIEAVTEAIKAGEKVTLTGFGTFSAVTRAARIGRNPATGQELQIAAKTSAKFSP
GKELKDLGQK

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=87, Percent_Identity=51.7241379310345, Blast_Score=88, Evalue=1e-19,
Organism=Escherichia coli, GI1790433, Length=87, Percent_Identity=45.9770114942529, Blast_Score=78, Evalue=1e-16,
Organism=Escherichia coli, GI1787141, Length=88, Percent_Identity=39.7727272727273, Blast_Score=74, Evalue=1e-15,
Organism=Escherichia coli, GI1788005, Length=86, Percent_Identity=36.046511627907, Blast_Score=66, Evalue=5e-13,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9410; Mature: 9279

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKAELVARMAESGDITKAAAEKALGGFIEAVTEAIKAGEKVTLTGFGTFSAVTRAARIG
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHC
RNPATGQELQIAAKTSAKFSPGKELKDLGQK
CCCCCCCEEEEEECCCCCCCCCHHHHHCCCC
>Mature Secondary Structure 
TKAELVARMAESGDITKAAAEKALGGFIEAVTEAIKAGEKVTLTGFGTFSAVTRAARIG
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHC
RNPATGQELQIAAKTSAKFSPGKELKDLGQK
CCCCCCCEEEEEECCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]