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The map label for this gene is lytE [H]

Identifier: 118581051

GI number: 118581051

Start: 2867033

End: 2868082

Strand: Reverse

Name: lytE [H]

Synonym: Ppro_2639

Alternate gene names: 118581051

Gene position: 2868082-2867033 (Counterclockwise)

Preceding gene: 118581052

Following gene: 118581050

Centisome position: 71.56

GC content: 57.43

Gene sequence:

>1050_bases
ATGATACATAAACGGTACATATTACTGTCACTCTGTCTTGTTGCCCTTGCCTTGCCCCAGCTTGCCCTGGCGTCCAAAAC
GCATGTTGTCCGCAAGAGCGAATCTCTCCATACAATCGCCCGCAAATATCACGTCTCCGTCGCTGAACTCAAATCGGTCA
ACAACCTGAGCGGAATCAGGATCGACAAGGGTGCGCGACTGATCATCCCTTCCGATTCCTCGAACCGCTCAAAAAAAATA
AAAATGGCCGAAAAAGCCCATGTCTATCGGGTTGTCAAGGGGGATACCCTGCCGAGGGTCGCCCGCAAGACAGGAATCCG
CATGGCCGAACTGCGCCGTTTGAACGGCCTTAAGGGCAACAGGGTCAAGCCGGGGCAGGTGCTGGCCCTGAACGCGTCAC
GTCCGCTGGCCGATGATGCGCCGATGGCGGCAGCGGTGGCCACTGATCGACTCAAGATGGTCAACAGGGATCTGCTCAAT
GAGCAGGAGTTCAGCGATACCCTGGCTGAACTGACCGACATCGACAGCGATCGTCCGGTCGACCTGGCAAAGAACCTCGA
AGACAGCAGCAGTATCAGCAAAATCAAGAATACCGCCTACAGTTTCCTGGGGGCGCGTTACCGCTTTGGCGGCACCAGTC
GCACTGCCCTTGACTGCTCCAGTTTCATTCAGCAGGTGTTTCGCGACCACAATATCAGTCTTCCCCGTACCGCCCGTGAG
CAGTTCTATGCAGGGGCGGAGGTGCCGCGCGGCGACCTGCAGAAGGGTGATCTGGTCTTCTTCCAGACCTATGCCCGTTT
CCCGTCCCATGTGGGCATCTACCTGGGCAATCGCAAGATGATCCACGCTTCGTCCCGTGAACGTCGCGTGGTGATCTCCT
CCATGGACACCCCCTACTACCTCTCCCGTTTCCTGGGCGCCCGGCGTGTCGGCCTCGGCCAGAAGGGGTTTGACGACTTC
AATGAATTGCTGTCCGGTGTGGAGGAGGAGCGCGAGAGTGATGTGATGGCCAACGACACCCTCGGACTGTCGCTGACCAT
GAACAACTGA

Upstream 100 bases:

>100_bases
GGCAAAACAGGGCTGGAAGGACATTGCAATTGACTTTGCATACTTTTTGTTATATAGAGTATAGCCATGTTGGTTAAAAA
TAGAACAAAAAGGAGGAGGA

Downstream 100 bases:

>100_bases
TTCCGCGCCCTGTTTGCGTAGCCGTATCCAACGATCCGGGCCCCATGGCCCGGATTTTTTTTAGCCGGTATATCCATGAC
TGTCCTTCTGGCCTACATAT

Product: NLP/P60 protein

Products: NA

Alternate protein names: Cell wall-associated polypeptide CWBP33; Gamma-D-glutamate-meso-diaminopimelate muropeptidase lytE; Phosphatase-associated protein papQ [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MIHKRYILLSLCLVALALPQLALASKTHVVRKSESLHTIARKYHVSVAELKSVNNLSGIRIDKGARLIIPSDSSNRSKKI
KMAEKAHVYRVVKGDTLPRVARKTGIRMAELRRLNGLKGNRVKPGQVLALNASRPLADDAPMAAAVATDRLKMVNRDLLN
EQEFSDTLAELTDIDSDRPVDLAKNLEDSSSISKIKNTAYSFLGARYRFGGTSRTALDCSSFIQQVFRDHNISLPRTARE
QFYAGAEVPRGDLQKGDLVFFQTYARFPSHVGIYLGNRKMIHASSRERRVVISSMDTPYYLSRFLGARRVGLGQKGFDDF
NELLSGVEEERESDVMANDTLGLSLTMNN

Sequences:

>Translated_349_residues
MIHKRYILLSLCLVALALPQLALASKTHVVRKSESLHTIARKYHVSVAELKSVNNLSGIRIDKGARLIIPSDSSNRSKKI
KMAEKAHVYRVVKGDTLPRVARKTGIRMAELRRLNGLKGNRVKPGQVLALNASRPLADDAPMAAAVATDRLKMVNRDLLN
EQEFSDTLAELTDIDSDRPVDLAKNLEDSSSISKIKNTAYSFLGARYRFGGTSRTALDCSSFIQQVFRDHNISLPRTARE
QFYAGAEVPRGDLQKGDLVFFQTYARFPSHVGIYLGNRKMIHASSRERRVVISSMDTPYYLSRFLGARRVGLGQKGFDDF
NELLSGVEEERESDVMANDTLGLSLTMNN
>Mature_349_residues
MIHKRYILLSLCLVALALPQLALASKTHVVRKSESLHTIARKYHVSVAELKSVNNLSGIRIDKGARLIIPSDSSNRSKKI
KMAEKAHVYRVVKGDTLPRVARKTGIRMAELRRLNGLKGNRVKPGQVLALNASRPLADDAPMAAAVATDRLKMVNRDLLN
EQEFSDTLAELTDIDSDRPVDLAKNLEDSSSISKIKNTAYSFLGARYRFGGTSRTALDCSSFIQQVFRDHNISLPRTARE
QFYAGAEVPRGDLQKGDLVFFQTYARFPSHVGIYLGNRKMIHASSRERRVVISSMDTPYYLSRFLGARRVGLGQKGFDDF
NELLSGVEEERESDVMANDTLGLSLTMNN

Specific function: Cleaves gamma-D-glutamate-meso-diaminopimelate bonds. Cell wall hydrolase involved in cell autolysis [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Secreted, cell wall. Note=LysM repeats are thought to be involved in peptidoglycan binding [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1788501, Length=119, Percent_Identity=42.8571428571429, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1787944, Length=113, Percent_Identity=39.8230088495575, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1788001, Length=128, Percent_Identity=38.28125, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1786421, Length=116, Percent_Identity=36.2068965517241, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60 [H]

EC number: NA

Molecular weight: Translated: 38925; Mature: 38925

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHKRYILLSLCLVALALPQLALASKTHVVRKSESLHTIARKYHVSVAELKSVNNLSGIR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEE
IDKGARLIIPSDSSNRSKKIKMAEKAHVYRVVKGDTLPRVARKTGIRMAELRRLNGLKGN
ECCCCEEEEECCCCCCCHHHHHHHHHHEEEEECCCCHHHHHHHHCCHHHHHHHHCCCCCC
RVKPGQVLALNASRPLADDAPMAAAVATDRLKMVNRDLLNEQEFSDTLAELTDIDSDRPV
CCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
DLAKNLEDSSSISKIKNTAYSFLGARYRFGGTSRTALDCSSFIQQVFRDHNISLPRTARE
HHHHCCCCHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHH
QFYAGAEVPRGDLQKGDLVFFQTYARFPSHVGIYLGNRKMIHASSRERRVVISSMDTPYY
HHHCCCCCCCCCCCCCCEEEEEHHHCCCCCEEEEECCCEEEECCCCCCEEEEECCCCHHH
LSRFLGARRVGLGQKGFDDFNELLSGVEEERESDVMANDTLGLSLTMNN
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEECCCEEEEEEECC
>Mature Secondary Structure
MIHKRYILLSLCLVALALPQLALASKTHVVRKSESLHTIARKYHVSVAELKSVNNLSGIR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEE
IDKGARLIIPSDSSNRSKKIKMAEKAHVYRVVKGDTLPRVARKTGIRMAELRRLNGLKGN
ECCCCEEEEECCCCCCCHHHHHHHHHHEEEEECCCCHHHHHHHHCCHHHHHHHHCCCCCC
RVKPGQVLALNASRPLADDAPMAAAVATDRLKMVNRDLLNEQEFSDTLAELTDIDSDRPV
CCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
DLAKNLEDSSSISKIKNTAYSFLGARYRFGGTSRTALDCSSFIQQVFRDHNISLPRTARE
HHHHCCCCHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHH
QFYAGAEVPRGDLQKGDLVFFQTYARFPSHVGIYLGNRKMIHASSRERRVVISSMDTPYY
HHHCCCCCCCCCCCCCCEEEEEHHHCCCCCEEEEECCCEEEECCCCCCEEEEECCCCHHH
LSRFLGARRVGLGQKGFDDFNELLSGVEEERESDVMANDTLGLSLTMNN
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEECCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9457885; 9579061; 9384377; 8045898 [H]