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The map label for this gene is mrdB [H]

Identifier: 118580956

GI number: 118580956

Start: 2757286

End: 2758386

Strand: Reverse

Name: mrdB [H]

Synonym: Ppro_2544

Alternate gene names: 118580956

Gene position: 2758386-2757286 (Counterclockwise)

Preceding gene: 118580957

Following gene: 118580955

Centisome position: 68.82

GC content: 60.04

Gene sequence:

>1101_bases
ATGATTGACCGCCGATTGTTCACCAACATCGACTGGACCCTGACCGCCCTGGCCCTGGTCATCTGCCTGGTGGGAATAGC
CAACATCTACAGCGCCTCATTCTCCTATGCCCCGGTGGGCGATCCCTACTTCATCAAGCAGTTCTACTGGCTCTTCTTCG
GCTTGTTCGTGGCCGTGGCGGTCTGCTGCGTGGATTACCACCTGCTGGAGGACTTCTCCTACTGGCTGTACGGTTTCGTT
CTGTTTCTGCTGCTGATGGTGCTGCTTTTCGGACGGACCTCCATGGGCGCCACCCGCTGGCTGAACCTGGGGCTCTTCAG
TCTCCAGCCGTCTGAACCGATGAAGATTGTTGTCATCGTGACCTTTGCCCGTTTCTTCAGCCGTTTTCACGCCGATGGCG
GCATGACGGTGCGGGACGTGCTCATCCCCCTGGCGATACTGGCCGTGCCTGCGATGCTGATCATGAAGCAGCCGGACCTG
GGTACCGCAACCCTGGTGATCCTGATCGCCTTCTCCATGGCTTTCTATGTCGGCTTGCGCTGGTCCACGGTGGTTACCTT
CGCGCTGGTCACCATACCGCTGGTCTGGTTCTCCTGGGCCCAGTTGCTGCGCCCCTACCAGAAGAACCGGGTGCTGGATT
TCCTCAATCCCGAGCGTTCGCGCCTGGGCAGCGGCTACCACATCATCCAGAGCAAGATTGCCGTCGGTTCCGGCGGTTTT
CTGGGCAAGGGGTATATCAAGGGAACCCAGTCCCAGCTCCGTTTCCTGCCGGAACAGCACACCGACTTCGCCTTCTCGGT
TTTCGCCGAGGAGTGGGGCTTTATCGGCTGTCTGATCCTGATCGCCCTCTACCTTTGCCTGGTGCTGTGGGGGCTGAACA
TTGCCCGGCGCTGCAACGACCGCTTCGGCAGCCTGCTGGCCATGGGGGTGACCGCCATGCTCTTCTGGCACATCGTCATC
AACATGGGCATGGTGATCGGCCTGTTCCCGGTGGTGGGGGTGCCGCTGCCGTTCTTCTCCTACGGCGGGACCTCAATGAT
CACCTCCATGGTGGGGATCGGCATCCTGCAGAGCATCAGCATGCGCAGGTTCATGTTCTGA

Upstream 100 bases:

>100_bases
GTGGCCCGCCCTGTGGCTGAGAAAGAAACGGAGGCCGAAGAGGAGACGGACGAGGCTCCGGCGACGGAACAGCAGCCACA
CCCGGATGGGGAGGAACGCA

Downstream 100 bases:

>100_bases
AATCGAAAGCTTTACGGGAGGCATTAGTGCTACTGCAGAATGAGCGTGAGGAGATCGTCCGTTTCGGCCGCAAAATGGTC
AGTGCCCGGCTTACCTCGGG

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MIDRRLFTNIDWTLTALALVICLVGIANIYSASFSYAPVGDPYFIKQFYWLFFGLFVAVAVCCVDYHLLEDFSYWLYGFV
LFLLLMVLLFGRTSMGATRWLNLGLFSLQPSEPMKIVVIVTFARFFSRFHADGGMTVRDVLIPLAILAVPAMLIMKQPDL
GTATLVILIAFSMAFYVGLRWSTVVTFALVTIPLVWFSWAQLLRPYQKNRVLDFLNPERSRLGSGYHIIQSKIAVGSGGF
LGKGYIKGTQSQLRFLPEQHTDFAFSVFAEEWGFIGCLILIALYLCLVLWGLNIARRCNDRFGSLLAMGVTAMLFWHIVI
NMGMVIGLFPVVGVPLPFFSYGGTSMITSMVGIGILQSISMRRFMF

Sequences:

>Translated_366_residues
MIDRRLFTNIDWTLTALALVICLVGIANIYSASFSYAPVGDPYFIKQFYWLFFGLFVAVAVCCVDYHLLEDFSYWLYGFV
LFLLLMVLLFGRTSMGATRWLNLGLFSLQPSEPMKIVVIVTFARFFSRFHADGGMTVRDVLIPLAILAVPAMLIMKQPDL
GTATLVILIAFSMAFYVGLRWSTVVTFALVTIPLVWFSWAQLLRPYQKNRVLDFLNPERSRLGSGYHIIQSKIAVGSGGF
LGKGYIKGTQSQLRFLPEQHTDFAFSVFAEEWGFIGCLILIALYLCLVLWGLNIARRCNDRFGSLLAMGVTAMLFWHIVI
NMGMVIGLFPVVGVPLPFFSYGGTSMITSMVGIGILQSISMRRFMF
>Mature_366_residues
MIDRRLFTNIDWTLTALALVICLVGIANIYSASFSYAPVGDPYFIKQFYWLFFGLFVAVAVCCVDYHLLEDFSYWLYGFV
LFLLLMVLLFGRTSMGATRWLNLGLFSLQPSEPMKIVVIVTFARFFSRFHADGGMTVRDVLIPLAILAVPAMLIMKQPDL
GTATLVILIAFSMAFYVGLRWSTVVTFALVTIPLVWFSWAQLLRPYQKNRVLDFLNPERSRLGSGYHIIQSKIAVGSGGF
LGKGYIKGTQSQLRFLPEQHTDFAFSVFAEEWGFIGCLILIALYLCLVLWGLNIARRCNDRFGSLLAMGVTAMLFWHIVI
NMGMVIGLFPVVGVPLPFFSYGGTSMITSMVGIGILQSISMRRFMF

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=316, Percent_Identity=46.2025316455696, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI1786277, Length=361, Percent_Identity=29.0858725761773, Blast_Score=151, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41205; Mature: 41205

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDRRLFTNIDWTLTALALVICLVGIANIYSASFSYAPVGDPYFIKQFYWLFFGLFVAVA
CCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VCCVDYHLLEDFSYWLYGFVLFLLLMVLLFGRTSMGATRWLNLGLFSLQPSEPMKIVVIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCEEECCCCCCCEEEHHH
TFARFFSRFHADGGMTVRDVLIPLAILAVPAMLIMKQPDLGTATLVILIAFSMAFYVGLR
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
WSTVVTFALVTIPLVWFSWAQLLRPYQKNRVLDFLNPERSRLGSGYHIIQSKIAVGSGGF
HHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHCCCHHHHCCCCHHHHHHHHHCCCCCC
LGKGYIKGTQSQLRFLPEQHTDFAFSVFAEEWGFIGCLILIALYLCLVLWGLNIARRCND
CCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFGSLLAMGVTAMLFWHIVINMGMVIGLFPVVGVPLPFFSYGGTSMITSMVGIGILQSIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHH
MRRFMF
HHHHCC
>Mature Secondary Structure
MIDRRLFTNIDWTLTALALVICLVGIANIYSASFSYAPVGDPYFIKQFYWLFFGLFVAVA
CCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VCCVDYHLLEDFSYWLYGFVLFLLLMVLLFGRTSMGATRWLNLGLFSLQPSEPMKIVVIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCEEECCCCCCCEEEHHH
TFARFFSRFHADGGMTVRDVLIPLAILAVPAMLIMKQPDLGTATLVILIAFSMAFYVGLR
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
WSTVVTFALVTIPLVWFSWAQLLRPYQKNRVLDFLNPERSRLGSGYHIIQSKIAVGSGGF
HHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHCCCHHHHCCCCHHHHHHHHHCCCCCC
LGKGYIKGTQSQLRFLPEQHTDFAFSVFAEEWGFIGCLILIALYLCLVLWGLNIARRCND
CCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFGSLLAMGVTAMLFWHIVINMGMVIGLFPVVGVPLPFFSYGGTSMITSMVGIGILQSIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHH
MRRFMF
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]