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The map label for this gene is fucA [H]

Identifier: 118580955

GI number: 118580955

Start: 2756546

End: 2757259

Strand: Reverse

Name: fucA [H]

Synonym: Ppro_2543

Alternate gene names: 118580955

Gene position: 2757259-2756546 (Counterclockwise)

Preceding gene: 118580956

Following gene: 118580950

Centisome position: 68.79

GC content: 64.01

Gene sequence:

>714_bases
GTGCTACTGCAGAATGAGCGTGAGGAGATCGTCCGTTTCGGCCGCAAAATGGTCAGTGCCCGGCTTACCTCGGGGACTGG
CGGCAACCTGAGCGTCATCGACCGGGACGCTGGGCTGGTGGCCATCAGTCCCAGCGGGATGGAATACGACGAGACCGAGC
CCGCGGATGTTCCGGTGCTGGACCTGGACGGCGTTGCCGTAACCGGGGAACGCAAACCGTCCAGTGAGTTCGGCTTTCAC
CTGGCGCTCTACCATGCCCGCCCCGACATCGGAGCCGTGGTGCACACCCATTCGGTCTACGCCACCACCATGGCCTGTCT
GGGCTGGGAGATCCCGGCCGTGCACTATCTGGTGGCCTTCTCGGGACACAAGGTGCCCCTTGCCCCCTATGCCACCTTTG
GCAGCCGGGAGCTGGCCGACAGCGTTGCCGGTTCCATCGGTGAGCACAATGCCCTGCTGCTGGCCAACCACGGCCTGGTG
GCCGTGGGTCCCAACCTGGCCACCGCCTTTGCCGTTGCCGAGGAGATCGAGCTGGTGGCACAGATCTACTACCAAGCCAA
GTGCATCGGCGAACCGGTCATGGTTCCCCAGGACGAGATGGAGCGGGTGATCGGCAAGTTCGCCGTGTACGGCCAGAGGG
GGACAACCGGTTCGGGTGCTGGGGGTGTAAATAAATTCGACGCGGCTGGGCAAAACCGGGAAGAGGTGCACTGA

Upstream 100 bases:

>100_bases
GGACCTCAATGATCACCTCCATGGTGGGGATCGGCATCCTGCAGAGCATCAGCATGCGCAGGTTCATGTTCTGAAATCGA
AAGCTTTACGGGAGGCATTA

Downstream 100 bases:

>100_bases
TCGCCATCATTTCCCAAACGTAAAAAAAGACGGTACCCACAGGTACCGTCTTTTTTGGTCAACGCGACGACTGCTTCCAG
CGCTAGCGGTTTATGCGCCG

Product: class II aldolase/adducin family protein

Products: NA

Alternate protein names: L-fuculose-1-phosphate aldolase [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MLLQNEREEIVRFGRKMVSARLTSGTGGNLSVIDRDAGLVAISPSGMEYDETEPADVPVLDLDGVAVTGERKPSSEFGFH
LALYHARPDIGAVVHTHSVYATTMACLGWEIPAVHYLVAFSGHKVPLAPYATFGSRELADSVAGSIGEHNALLLANHGLV
AVGPNLATAFAVAEEIELVAQIYYQAKCIGEPVMVPQDEMERVIGKFAVYGQRGTTGSGAGGVNKFDAAGQNREEVH

Sequences:

>Translated_237_residues
MLLQNEREEIVRFGRKMVSARLTSGTGGNLSVIDRDAGLVAISPSGMEYDETEPADVPVLDLDGVAVTGERKPSSEFGFH
LALYHARPDIGAVVHTHSVYATTMACLGWEIPAVHYLVAFSGHKVPLAPYATFGSRELADSVAGSIGEHNALLLANHGLV
AVGPNLATAFAVAEEIELVAQIYYQAKCIGEPVMVPQDEMERVIGKFAVYGQRGTTGSGAGGVNKFDAAGQNREEVH
>Mature_237_residues
MLLQNEREEIVRFGRKMVSARLTSGTGGNLSVIDRDAGLVAISPSGMEYDETEPADVPVLDLDGVAVTGERKPSSEFGFH
LALYHARPDIGAVVHTHSVYATTMACLGWEIPAVHYLVAFSGHKVPLAPYATFGSRELADSVAGSIGEHNALLLANHGLV
AVGPNLATAFAVAEEIELVAQIYYQAKCIGEPVMVPQDEMERVIGKFAVYGQRGTTGSGAGGVNKFDAAGQNREEVH

Specific function: Fucose metabolism; third step. [C]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789164, Length=207, Percent_Identity=41.0628019323672, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1789094, Length=187, Percent_Identity=35.8288770053476, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790642, Length=112, Percent_Identity=41.0714285714286, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786247, Length=113, Percent_Identity=37.1681415929204, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1790008, Length=113, Percent_Identity=35.3982300884956, Blast_Score=74, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR004782 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.1.2.17 [H]

Molecular weight: Translated: 25191; Mature: 25191

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLQNEREEIVRFGRKMVSARLTSGTGGNLSVIDRDAGLVAISPSGMEYDETEPADVPVL
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCEE
DLDGVAVTGERKPSSEFGFHLALYHARPDIGAVVHTHSVYATTMACLGWEIPAVHYLVAF
ECCCEEEECCCCCCCCCCEEEEEEECCCCCCEEEEHHHHHHHHHHHHCCCCCCEEEEEEE
SGHKVPLAPYATFGSRELADSVAGSIGEHNALLLANHGLVAVGPNLATAFAVAEEIELVA
CCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHHHH
QIYYQAKCIGEPVMVPQDEMERVIGKFAVYGQRGTTGSGAGGVNKFDAAGQNREEVH
HHHHHHHHCCCCCCCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLLQNEREEIVRFGRKMVSARLTSGTGGNLSVIDRDAGLVAISPSGMEYDETEPADVPVL
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCEE
DLDGVAVTGERKPSSEFGFHLALYHARPDIGAVVHTHSVYATTMACLGWEIPAVHYLVAF
ECCCEEEECCCCCCCCCCEEEEEEECCCCCCEEEEHHHHHHHHHHHHCCCCCCEEEEEEE
SGHKVPLAPYATFGSRELADSVAGSIGEHNALLLANHGLVAVGPNLATAFAVAEEIELVA
CCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHHHH
QIYYQAKCIGEPVMVPQDEMERVIGKFAVYGQRGTTGSGAGGVNKFDAAGQNREEVH
HHHHHHHHCCCCCCCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]