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The map label for this gene is pyrR [H]

Identifier: 118580942

GI number: 118580942

Start: 2742477

End: 2743034

Strand: Reverse

Name: pyrR [H]

Synonym: Ppro_2530

Alternate gene names: 118580942

Gene position: 2743034-2742477 (Counterclockwise)

Preceding gene: 118580943

Following gene: 118580941

Centisome position: 68.44

GC content: 62.19

Gene sequence:

>558_bases
ATGTCTACGCGAGGTGACGACATGGCAGACGAAAAGACCGTGATTCTGGACAACTCCGGCATAAAACGGGCCTTGACCCG
CATTTCCCACGAGATTCTGGAGCGCAACAAGGGGCTGGATGACGTCGTCCTGATCGGCATCCGTTCCGGCGGGGCCTTCC
TGGCAACGGAACTTGCCGCTACCCTTGAGGATATCGAAGGGATAAAGCCGGCGGTGGGGACGGTGGACATCACCCTCTAC
CGTGACGATGTGGGCAGCAGCCAGTCCCGCCAGCCGGTGGGCAGGACCGACATCCCCTTCTCCGTGGAGAACAAACGGGT
CGTGCTGGTGGATGACGTGCTCTGTACCGGCCGCACCATTCGCGCCGCCATGGACGCCCTGATGGACCACGGCCGGCCCC
GCTGCATCCAGCTGGCGGTGCTGATCGACCGGGGGCACCGCGATCTCCCCATCCGGGCCGACTACGTGGGGCGCAACGTG
CCGACCAGCATGAAAGAGAACGTTCAGGTTATTTTCGACGCCGCCAACCATGCGTGCGAAGTGCTGTTGGAAAAATAG

Upstream 100 bases:

>100_bases
TCCAGTCCGAGAGGCTGGCAAGGGTACCAATCGATGACCAGCCGAATAATTCATAGGACAGAAGAGTCTTGCCGCGCGTG
CACGGTGAGGCTCTTTTTTT

Downstream 100 bases:

>100_bases
GGGAGGGTGGCATGGCGAACTTCAAACACAAGGACATCATCGCGCTGCAGGACCTGACCAAACAGGAGATCGAACTGCTG
CTGTCCACGGCGGAGAGCAT

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MSTRGDDMADEKTVILDNSGIKRALTRISHEILERNKGLDDVVLIGIRSGGAFLATELAATLEDIEGIKPAVGTVDITLY
RDDVGSSQSRQPVGRTDIPFSVENKRVVLVDDVLCTGRTIRAAMDALMDHGRPRCIQLAVLIDRGHRDLPIRADYVGRNV
PTSMKENVQVIFDAANHACEVLLEK

Sequences:

>Translated_185_residues
MSTRGDDMADEKTVILDNSGIKRALTRISHEILERNKGLDDVVLIGIRSGGAFLATELAATLEDIEGIKPAVGTVDITLY
RDDVGSSQSRQPVGRTDIPFSVENKRVVLVDDVLCTGRTIRAAMDALMDHGRPRCIQLAVLIDRGHRDLPIRADYVGRNV
PTSMKENVQVIFDAANHACEVLLEK
>Mature_184_residues
STRGDDMADEKTVILDNSGIKRALTRISHEILERNKGLDDVVLIGIRSGGAFLATELAATLEDIEGIKPAVGTVDITLYR
DDVGSSQSRQPVGRTDIPFSVENKRVVLVDDVLCTGRTIRAAMDALMDHGRPRCIQLAVLIDRGHRDLPIRADYVGRNVP
TSMKENVQVIFDAANHACEVLLEK

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 20276; Mature: 20145

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRGDDMADEKTVILDNSGIKRALTRISHEILERNKGLDDVVLIGIRSGGAFLATELAA
CCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHH
TLEDIEGIKPAVGTVDITLYRDDVGSSQSRQPVGRTDIPFSVENKRVVLVDDVLCTGRTI
HHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEECCCEEEEEECCHHCCHHH
RAAMDALMDHGRPRCIQLAVLIDRGHRDLPIRADYVGRNVPTSMKENVQVIFDAANHACE
HHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEHHHCCCCCCCCHHCCEEEEEECHHHHHH
VLLEK
HHCCC
>Mature Secondary Structure 
STRGDDMADEKTVILDNSGIKRALTRISHEILERNKGLDDVVLIGIRSGGAFLATELAA
CCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHH
TLEDIEGIKPAVGTVDITLYRDDVGSSQSRQPVGRTDIPFSVENKRVVLVDDVLCTGRTI
HHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEECCCEEEEEECCHHCCHHH
RAAMDALMDHGRPRCIQLAVLIDRGHRDLPIRADYVGRNVPTSMKENVQVIFDAANHACE
HHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEHHHCCCCCCCCHHCCEEEEEECHHHHHH
VLLEK
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA