| Definition | Pelobacter propionicus DSM 2379 chromosome, complete genome. |
|---|---|
| Accession | NC_008609 |
| Length | 4,008,000 |
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The map label for this gene is pyrB
Identifier: 118580941
GI number: 118580941
Start: 2741533
End: 2742465
Strand: Reverse
Name: pyrB
Synonym: Ppro_2529
Alternate gene names: 118580941
Gene position: 2742465-2741533 (Counterclockwise)
Preceding gene: 118580942
Following gene: 118580940
Centisome position: 68.42
GC content: 62.59
Gene sequence:
>933_bases ATGGCGAACTTCAAACACAAGGACATCATCGCGCTGCAGGACCTGACCAAACAGGAGATCGAACTGCTGCTGTCCACGGC GGAGAGCATGCGCGAGATCAACAATCGCGACATCAAGAAGGTCCCCACCCTGCGGGGCAAGACCATCGTCAACCTGTTCT ACGAGTCCTCGACCCGTACGCGTACCTCCTTCGAACTGGCCGCCAAGCGGCTCTCGGCGGATACGGTGAACATCTCTCCC TCCACCAGCTCCGCCACCAAGGGGGAGACCCTGGCAGACACTGCCCTGAACCTGCTGGCCATGAAACCGGACATCATCGT CATGCGCCACTCTGTTTCCGGGTCGCACTACTTCCTCTCCAAAAAACTCCCCTGCTCGATCGTCAATGCTGGGGACGGCG TCCATGAGCACCCCTCCCAGGGGCTCCTTGACATGCTGACCATGAAGGACCGCTTCGGCCGCCTTGACGGGCTGAAGGTG GCCATCGTGGGGGACATCAGCCACAGCCGGGTGGCCCGCTCCAACATCCAGGGGCTGACCAAACTGGGCTCCCAGGTCTT CCTGGCCGGTCCCCCGACCATGATGCCCCCCGGCGTGGAGCGCCTGGGCAACGTCACCGTCTGCGACTCGCTGCGAGAGG CCATCCAGGATGCCGATGTGGTCATGATGCTGCGCATCCAGCAGGAGCGCCAGGGCAAGACCCTCATGCCCAACGCCCGC GAGTATGCGCGCTATTTTGGCCTCAACCCGGAGAACCTCAAGCTGGCCAAGCCGGATGCCATGGTCATGCACCCCGGCCC GATCAACCGCGGGGTGGAGATGGCCAGCAGCGTGGTGGATGGCGACCAGTCCTGGATCCTGAAACAGGTGGAGAACGGCG TGGCCGTCAGGATGTCCATGCTCTACCACGTCTGCGAAGGGGAGCTGGAATAA
Upstream 100 bases:
>100_bases GGCGCAACGTGCCGACCAGCATGAAAGAGAACGTTCAGGTTATTTTCGACGCCGCCAACCATGCGTGCGAAGTGCTGTTG GAAAAATAGGGGAGGGTGGC
Downstream 100 bases:
>100_bases ACCGGTTCGTGGTTCAAGGTTCAGGGGGCGTGGATTAAACCTTGAGCCTCGAGCCTCGAACCTGGAACCAATATAATGAG GTGATGACATGAACCTTCTG
Product: aspartate carbamoyltransferase catalytic subunit
Products: NA
Alternate protein names: Aspartate transcarbamylase; ATCase
Number of amino acids: Translated: 310; Mature: 309
Protein sequence:
>310_residues MANFKHKDIIALQDLTKQEIELLLSTAESMREINNRDIKKVPTLRGKTIVNLFYESSTRTRTSFELAAKRLSADTVNISP STSSATKGETLADTALNLLAMKPDIIVMRHSVSGSHYFLSKKLPCSIVNAGDGVHEHPSQGLLDMLTMKDRFGRLDGLKV AIVGDISHSRVARSNIQGLTKLGSQVFLAGPPTMMPPGVERLGNVTVCDSLREAIQDADVVMMLRIQQERQGKTLMPNAR EYARYFGLNPENLKLAKPDAMVMHPGPINRGVEMASSVVDGDQSWILKQVENGVAVRMSMLYHVCEGELE
Sequences:
>Translated_310_residues MANFKHKDIIALQDLTKQEIELLLSTAESMREINNRDIKKVPTLRGKTIVNLFYESSTRTRTSFELAAKRLSADTVNISP STSSATKGETLADTALNLLAMKPDIIVMRHSVSGSHYFLSKKLPCSIVNAGDGVHEHPSQGLLDMLTMKDRFGRLDGLKV AIVGDISHSRVARSNIQGLTKLGSQVFLAGPPTMMPPGVERLGNVTVCDSLREAIQDADVVMMLRIQQERQGKTLMPNAR EYARYFGLNPENLKLAKPDAMVMHPGPINRGVEMASSVVDGDQSWILKQVENGVAVRMSMLYHVCEGELE >Mature_309_residues ANFKHKDIIALQDLTKQEIELLLSTAESMREINNRDIKKVPTLRGKTIVNLFYESSTRTRTSFELAAKRLSADTVNISPS TSSATKGETLADTALNLLAMKPDIIVMRHSVSGSHYFLSKKLPCSIVNAGDGVHEHPSQGLLDMLTMKDRFGRLDGLKVA IVGDISHSRVARSNIQGLTKLGSQVFLAGPPTMMPPGVERLGNVTVCDSLREAIQDADVVMMLRIQQERQGKTLMPNARE YARYFGLNPENLKLAKPDAMVMHPGPINRGVEMASSVVDGDQSWILKQVENGVAVRMSMLYHVCEGELE
Specific function: Pyrimidine biosynthesis; second step. [C]
COG id: COG0540
COG function: function code F; Aspartate carbamoyltransferase, catalytic chain
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the ATCase/OTCase family
Homologues:
Organism=Homo sapiens, GI18105007, Length=307, Percent_Identity=34.8534201954397, Blast_Score=176, Evalue=2e-44, Organism=Escherichia coli, GI2367364, Length=322, Percent_Identity=34.7826086956522, Blast_Score=164, Evalue=6e-42, Organism=Escherichia coli, GI1790703, Length=323, Percent_Identity=23.8390092879257, Blast_Score=71, Evalue=8e-14, Organism=Caenorhabditis elegans, GI193204318, Length=322, Percent_Identity=32.2981366459627, Blast_Score=127, Evalue=7e-30, Organism=Saccharomyces cerevisiae, GI6322331, Length=308, Percent_Identity=31.4935064935065, Blast_Score=149, Evalue=6e-37, Organism=Drosophila melanogaster, GI24642586, Length=314, Percent_Identity=30.5732484076433, Blast_Score=143, Evalue=2e-34,
Paralogues:
None
Copy number: 2080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 14328 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]
Swissprot (AC and ID): PYRB_PELPD (A1AS13)
Other databases:
- EMBL: CP000482 - RefSeq: YP_902191.1 - ProteinModelPortal: A1AS13 - SMR: A1AS13 - STRING: A1AS13 - GeneID: 4571554 - GenomeReviews: CP000482_GR - KEGG: ppd:Ppro_2529 - eggNOG: COG0540 - HOGENOM: HBG579429 - OMA: MNRGLEI - PhylomeDB: A1AS13 - ProtClustDB: PRK00856 - HAMAP: MF_00001 - InterPro: IPR006132 - InterPro: IPR006130 - InterPro: IPR006131 - InterPro: IPR002082 - PRINTS: PR00100 - PRINTS: PR00101 - TIGRFAMs: TIGR00670
Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N; SSF53671 Asp/Orn_carbamoyltranf
EC number: =2.1.3.2
Molecular weight: Translated: 34173; Mature: 34042
Theoretical pI: Translated: 8.47; Mature: 8.47
Prosite motif: PS00097 CARBAMOYLTRANSFERASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.0 %Cys (Translated Protein) 5.2 %Met (Translated Protein) 6.1 %Cys+Met (Translated Protein) 1.0 %Cys (Mature Protein) 4.9 %Met (Mature Protein) 5.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MANFKHKDIIALQDLTKQEIELLLSTAESMREINNRDIKKVPTLRGKTIVNLFYESSTRT CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEEEEEECCCCCC RTSFELAAKRLSADTVNISPSTSSATKGETLADTALNLLAMKPDIIVMRHSVSGSHYFLS HHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHEECCCEEEEEECCCCCEEEEC KKLPCSIVNAGDGVHEHPSQGLLDMLTMKDRFGRLDGLKVAIVGDISHSRVARSNIQGLT CCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHH KLGSQVFLAGPPTMMPPGVERLGNVTVCDSLREAIQDADVVMMLRIQQERQGKTLMPNAR HCCCEEEEECCCCCCCCCHHHHCCCHHHHHHHHHHCCCCEEEEEEEHHHHCCCCCCCCHH EYARYFGLNPENLKLAKPDAMVMHPGPINRGVEMASSVVDGDQSWILKQVENGVAVRMSM HHHHHHCCCCCCEEEECCCEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHH LYHVCEGELE HHHHHCCCCC >Mature Secondary Structure ANFKHKDIIALQDLTKQEIELLLSTAESMREINNRDIKKVPTLRGKTIVNLFYESSTRT CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEEEEEECCCCCC RTSFELAAKRLSADTVNISPSTSSATKGETLADTALNLLAMKPDIIVMRHSVSGSHYFLS HHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHEECCCEEEEEECCCCCEEEEC KKLPCSIVNAGDGVHEHPSQGLLDMLTMKDRFGRLDGLKVAIVGDISHSRVARSNIQGLT CCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHH KLGSQVFLAGPPTMMPPGVERLGNVTVCDSLREAIQDADVVMMLRIQQERQGKTLMPNAR HCCCEEEEECCCCCCCCCHHHHCCCHHHHHHHHHHCCCCEEEEEEEHHHHCCCCCCCCHH EYARYFGLNPENLKLAKPDAMVMHPGPINRGVEMASSVVDGDQSWILKQVENGVAVRMSM HHHHHHCCCCCCEEEECCCEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHH LYHVCEGELE HHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA