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The map label for this gene is atoS [H]

Identifier: 118580923

GI number: 118580923

Start: 2719203

End: 2720834

Strand: Reverse

Name: atoS [H]

Synonym: Ppro_2511

Alternate gene names: 118580923

Gene position: 2720834-2719203 (Counterclockwise)

Preceding gene: 118580924

Following gene: 118580922

Centisome position: 67.89

GC content: 61.58

Gene sequence:

>1632_bases
ATGTGGCGTGAACGGCAGCTGCGGATTTTTATCTATGCCAGGATTCTGGTCAGTTTCCTGTTTCTGGTTTCCACGGTTGC
GTTGATGCTGAAGGAGCCTGAAGCCATGGACGATATCACCCACAACGGGGTGATTCGTCTGATGGCTTTTTCCTTTCTCT
TCTCGGCCATTTCGCACTTCTCGCTCAAACTCCCCCGCTTTCGTCACTTCATCACCTATCTGCAGACCATCTGGGACCTG
TTGTTCGTTACGGTGCTGCTGCTGTTCACCGGCGGGGTGGACAGCCCCTACTCCTTCCTGTACCTGCTCTCCATCATGAA
CGCCGGCGTGCTCCTGGGACGCCGGGAGGCGTTCTACACCGCGTCCCTGTGCGGAATCCTCTACGGTGCCATCAGCGATT
TCCAGTATTTCGGCTATCTGGAGGTCATAGGCCTGAGCCGGGAGGCGGCCCACGCATTCGGCGGGATGCAGATCCTCTAT
AACATATTCATGAACCTGATGGGGTTTGGTCTGACCGGCTTCATCACCGGGTACCTCTCCCAGCAGGCCAGGCAGAACGC
CGACGCCCTGGAACGAAAGAACGTCAACCTGGAAGAACTGGAGCGCCTGAACCGGACCATCGTTGCCAACCTGGAGAGCG
GCCTGATAACGGTGACGCGGGAGGGGACCATCCGAGTCTTCAATCGCTATGCCGAGGAGCTGACGAAAAAAACGCAGCAG
GATGTCTATGATCTGCCGCTGGAGCGGCTCTTTCCGGAGATGGCGGCGTCCGTCCGGGGAGAGCAGGGCAGGACGAGCAG
CGGTGAGTGCGCCTGGAAGGGGGCCGATGGGGAGGCGCTTGTCCTGGGCTACAGCAGCGTCCCCTTTAGCGACGGCCGGG
GCGAACTGGCCGGAGCGATCATCAACTTCAAGGACCTGACCGACAAGATTCGCATGGAAGAGGCGCTTAGGCGCAGCGAC
AAGCTGGCCGTGCTGGGCTCGCTGGCCGCCCGCATGGCCCATGAGATTCGCAACCCCCTGGCGGCCATGAGCGGTTCGGT
GCAGTTGCTCGCCGATCATGGCACCGTTGCCGAGAATGACCAGCGTCTGCTGGCGATCATCCTGCGGGAAACCGACCGAC
TCAACGCGCTGATCACCAGTTTTCTGACCTATGCCCGCCCCGTCTCTCCCCACAAGGAACGCATCAGCCTGGGGGGGCTG
ATCGACGAGGTGCGTCTCCTGGTCTCCTCGGACCGCCGCTTCGGCGGCATAACCCTCACCGCCCAGGTCCCGGAACGAAT
GACCATCAGCGCCGACCAGAACCAGCTGCGCCAGGTTCTGATAAATCTGCTGAACAATGCCGCCGAGGCAATGCCCGAGG
GGGGCAGGGTGGAGATCTCCGCGCACCTGGCCAGCCCCGAAGACGGGGATAGGGCGGAACAACGAGCGGTGATCACCGTC
AGCGACAGCGGCTCCGGGATCACGGACGAGGTGGCGGCCCACCTGTTCGAGCCGTTCTGGACCACCAAGAGCGATGGATG
TGGCTTGGGGCTGGCGATTACCTACCGCATCATCGAAGAGCATGGCGGCACGATCACGGCGGAATCGCCTCCCTGGGGAG
GGTGCCGCATCACCATCTCGCTTCCGGCCTGA

Upstream 100 bases:

>100_bases
GCCGCTGCTGATGGTCTTCCTGGGCACCACCGTGGGTGGTCTGGTCATTGCCATGTATCTGCCGATCTTCAAGCTGGCGG
GGACTGTCGGCGGATAACCT

Downstream 100 bases:

>100_bases
CCGCTGAGTCTGGAAACGGCAGGTGACAGGTGCCGCAGTGAGCCCAAGAGCCGCGAACGCAGGCAGCTTTCACCTGCCGC
ATGTGGGGCAAATCCCGTTC

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 543; Mature: 543

Protein sequence:

>543_residues
MWRERQLRIFIYARILVSFLFLVSTVALMLKEPEAMDDITHNGVIRLMAFSFLFSAISHFSLKLPRFRHFITYLQTIWDL
LFVTVLLLFTGGVDSPYSFLYLLSIMNAGVLLGRREAFYTASLCGILYGAISDFQYFGYLEVIGLSREAAHAFGGMQILY
NIFMNLMGFGLTGFITGYLSQQARQNADALERKNVNLEELERLNRTIVANLESGLITVTREGTIRVFNRYAEELTKKTQQ
DVYDLPLERLFPEMAASVRGEQGRTSSGECAWKGADGEALVLGYSSVPFSDGRGELAGAIINFKDLTDKIRMEEALRRSD
KLAVLGSLAARMAHEIRNPLAAMSGSVQLLADHGTVAENDQRLLAIILRETDRLNALITSFLTYARPVSPHKERISLGGL
IDEVRLLVSSDRRFGGITLTAQVPERMTISADQNQLRQVLINLLNNAAEAMPEGGRVEISAHLASPEDGDRAEQRAVITV
SDSGSGITDEVAAHLFEPFWTTKSDGCGLGLAITYRIIEEHGGTITAESPPWGGCRITISLPA

Sequences:

>Translated_543_residues
MWRERQLRIFIYARILVSFLFLVSTVALMLKEPEAMDDITHNGVIRLMAFSFLFSAISHFSLKLPRFRHFITYLQTIWDL
LFVTVLLLFTGGVDSPYSFLYLLSIMNAGVLLGRREAFYTASLCGILYGAISDFQYFGYLEVIGLSREAAHAFGGMQILY
NIFMNLMGFGLTGFITGYLSQQARQNADALERKNVNLEELERLNRTIVANLESGLITVTREGTIRVFNRYAEELTKKTQQ
DVYDLPLERLFPEMAASVRGEQGRTSSGECAWKGADGEALVLGYSSVPFSDGRGELAGAIINFKDLTDKIRMEEALRRSD
KLAVLGSLAARMAHEIRNPLAAMSGSVQLLADHGTVAENDQRLLAIILRETDRLNALITSFLTYARPVSPHKERISLGGL
IDEVRLLVSSDRRFGGITLTAQVPERMTISADQNQLRQVLINLLNNAAEAMPEGGRVEISAHLASPEDGDRAEQRAVITV
SDSGSGITDEVAAHLFEPFWTTKSDGCGLGLAITYRIIEEHGGTITAESPPWGGCRITISLPA
>Mature_543_residues
MWRERQLRIFIYARILVSFLFLVSTVALMLKEPEAMDDITHNGVIRLMAFSFLFSAISHFSLKLPRFRHFITYLQTIWDL
LFVTVLLLFTGGVDSPYSFLYLLSIMNAGVLLGRREAFYTASLCGILYGAISDFQYFGYLEVIGLSREAAHAFGGMQILY
NIFMNLMGFGLTGFITGYLSQQARQNADALERKNVNLEELERLNRTIVANLESGLITVTREGTIRVFNRYAEELTKKTQQ
DVYDLPLERLFPEMAASVRGEQGRTSSGECAWKGADGEALVLGYSSVPFSDGRGELAGAIINFKDLTDKIRMEEALRRSD
KLAVLGSLAARMAHEIRNPLAAMSGSVQLLADHGTVAENDQRLLAIILRETDRLNALITSFLTYARPVSPHKERISLGGL
IDEVRLLVSSDRRFGGITLTAQVPERMTISADQNQLRQVLINLLNNAAEAMPEGGRVEISAHLASPEDGDRAEQRAVITV
SDSGSGITDEVAAHLFEPFWTTKSDGCGLGLAITYRIIEEHGGTITAESPPWGGCRITISLPA

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=374, Percent_Identity=30.7486631016043, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=36.1702127659575, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1790300, Length=364, Percent_Identity=26.6483516483516, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1788393, Length=260, Percent_Identity=28.8461538461538, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1788713, Length=282, Percent_Identity=28.0141843971631, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87081816, Length=226, Percent_Identity=32.3008849557522, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1787894, Length=256, Percent_Identity=30.078125, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI48994928, Length=337, Percent_Identity=24.9258160237389, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1786600, Length=253, Percent_Identity=23.3201581027668, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790346, Length=225, Percent_Identity=29.3333333333333, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790861, Length=222, Percent_Identity=27.4774774774775, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI145693157, Length=263, Percent_Identity=26.2357414448669, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1789808, Length=220, Percent_Identity=26.8181818181818, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786912, Length=242, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786783, Length=259, Percent_Identity=23.9382239382239, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789149, Length=242, Percent_Identity=26.8595041322314, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60135; Mature: 60135

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWRERQLRIFIYARILVSFLFLVSTVALMLKEPEAMDDITHNGVIRLMAFSFLFSAISHF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHH
SLKLPRFRHFITYLQTIWDLLFVTVLLLFTGGVDSPYSFLYLLSIMNAGVLLGRREAFYT
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEECHHHHHH
ASLCGILYGAISDFQYFGYLEVIGLSREAAHAFGGMQILYNIFMNLMGFGLTGFITGYLS
HHHHHHHHHHHHHHHHHCHHHEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
QQARQNADALERKNVNLEELERLNRTIVANLESGLITVTREGTIRVFNRYAEELTKKTQQ
HHHHCCHHHHHHCCCCHHHHHHHHHHHEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHH
DVYDLPLERLFPEMAASVRGEQGRTSSGECAWKGADGEALVLGYSSVPFSDGRGELAGAI
HHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCCCCHHHHE
INFKDLTDKIRMEEALRRSDKLAVLGSLAARMAHEIRNPLAAMSGSVQLLADHGTVAEND
EEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHCCCCEEEEECCCCCCCCC
QRLLAIILRETDRLNALITSFLTYARPVSPHKERISLGGLIDEVRLLVSSDRRFGGITLT
CCEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
AQVPERMTISADQNQLRQVLINLLNNAAEAMPEGGRVEISAHLASPEDGDRAEQRAVITV
EECCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHCEEEEEE
SDSGSGITDEVAAHLFEPFWTTKSDGCGLGLAITYRIIEEHGGTITAESPPWGGCRITIS
ECCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEEEE
LPA
CCC
>Mature Secondary Structure
MWRERQLRIFIYARILVSFLFLVSTVALMLKEPEAMDDITHNGVIRLMAFSFLFSAISHF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHH
SLKLPRFRHFITYLQTIWDLLFVTVLLLFTGGVDSPYSFLYLLSIMNAGVLLGRREAFYT
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEECHHHHHH
ASLCGILYGAISDFQYFGYLEVIGLSREAAHAFGGMQILYNIFMNLMGFGLTGFITGYLS
HHHHHHHHHHHHHHHHHCHHHEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
QQARQNADALERKNVNLEELERLNRTIVANLESGLITVTREGTIRVFNRYAEELTKKTQQ
HHHHCCHHHHHHCCCCHHHHHHHHHHHEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHH
DVYDLPLERLFPEMAASVRGEQGRTSSGECAWKGADGEALVLGYSSVPFSDGRGELAGAI
HHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCCCCHHHHE
INFKDLTDKIRMEEALRRSDKLAVLGSLAARMAHEIRNPLAAMSGSVQLLADHGTVAEND
EEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHCCCCEEEEECCCCCCCCC
QRLLAIILRETDRLNALITSFLTYARPVSPHKERISLGGLIDEVRLLVSSDRRFGGITLT
CCEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
AQVPERMTISADQNQLRQVLINLLNNAAEAMPEGGRVEISAHLASPEDGDRAEQRAVITV
EECCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHCEEEEEE
SDSGSGITDEVAAHLFEPFWTTKSDGCGLGLAITYRIIEEHGGTITAESPPWGGCRITIS
ECCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEEEE
LPA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]