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The map label for this gene is csd [H]

Identifier: 118580908

GI number: 118580908

Start: 2703050

End: 2704207

Strand: Reverse

Name: csd [H]

Synonym: Ppro_2495

Alternate gene names: 118580908

Gene position: 2704207-2703050 (Counterclockwise)

Preceding gene: 118580909

Following gene: 118580907

Centisome position: 67.47

GC content: 67.96

Gene sequence:

>1158_bases
ATGACCTCCCGTTCCCCCCTCACCATCTATCTGGATAACGCGGCCACGTCCCACCCCAAGCCGGAATGCGTCTACCAGGC
CGTCGTGCATGCCATGCGCCACATCGGCGCCTCGCCGGGGCGTGCAGGGCACCGCCGCTCCCTGGAGGCGTCTCGCCTGC
TCTTCCAGGTCAGGGAGGCCATCGCCACCCTGCTTTCCGTCCCCGATTCGTCACGGATCATCTTCACCCACAGCGCCACC
GAGGCGCTCAACCTGGCCCTGCAGGGTGTCCTGCTGGCGGGCGATCATGTGGTTACCACCTCCATGGAGCATAACTCCCT
CCTGCGGCCGTTGTACCAGCTGCGCCGGCGGGGAGTTGAGCTGACCATTGTCGAGGCGGCCGGTGACGGCCTAGTGGACC
CGGACGCTGTACGGCGAGCCTTCCGACCCACCACCCGCATGCTGGCGCTGGGGCATGTCTCCAATGTGTGCGGCGCCATC
CAGCCGGTGGCCCGACTTGCAACCATCGCCCGCGAGGCCGGGGCGCTGTTTCTGCTGGATGCGGCCCAGTCGGCCGGCTC
GATCCCCATCGATGCGGCTGGCCTGGGGGTGGACCTGCTGGCCGCGCCGGGGCACAAGGGGTTGCTCGGTCCCCAGGGCA
CCGGTTTTCTGTTCGTTGCCGAGGGGGTGGAGATCAGGCCGCTTCTGGCCGGAGGAACCGGCAGCAACTCATCCAGCGAA
GAGCAGCCGCACATCCTGCCCGAGGGATTCGAGGCCGGAACCCACAACCTCCCCGGCATTGCCGGCCTGCTTGCGGGCGT
GGAGTTCGTCCTGGCCCGGGGGGTCGACGTCATTGGCCGCAGGGAGCGGGAGCATGTGGCCGAGGTGGCCAGGCGCCTGG
CGCCGCTTCCCGGCATGGCCATCCATGGTCCCTCTTTCCCCGCCAACCGGAGTGGCCTGCTCTCCTTTACCCTGGCGGGG
ATGGACGCCTCCAGCCTGGCCTTCATGCTGGACCAGCGCTTCGATATCGCCGTGCGGGCCGGCCTGCACTGCGCCCCCCT
GGCCCACCGCTCCCTGGGCACCTACCCCGCGGGAACCGTCCGGGTCAGTCCCGGATGGTTCACCAGCAACGACGAGATTG
CTATTTTCTGCGATGCCGTTGTAAAGTGTATCCCTTGA

Upstream 100 bases:

>100_bases
AATCCAGTATTGCGGCGAAACTGCTGGACGGGACCAAGGACCCCCGCGGCGGCCGGGTCGAGTTCTTCCCCTGGCTGGTG
CAGCGGCCGGTAAACGTACC

Downstream 100 bases:

>100_bases
GTAAAAAGGCCGTGACTGGTAATCCGTGACTGGCAACCAGTCACGAGTCACGGCTTCTCCGTTGTTCCAACCCATCCCGA
AAGGTCTGCATGAAAAACTT

Product: cysteine desulfurase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MTSRSPLTIYLDNAATSHPKPECVYQAVVHAMRHIGASPGRAGHRRSLEASRLLFQVREAIATLLSVPDSSRIIFTHSAT
EALNLALQGVLLAGDHVVTTSMEHNSLLRPLYQLRRRGVELTIVEAAGDGLVDPDAVRRAFRPTTRMLALGHVSNVCGAI
QPVARLATIAREAGALFLLDAAQSAGSIPIDAAGLGVDLLAAPGHKGLLGPQGTGFLFVAEGVEIRPLLAGGTGSNSSSE
EQPHILPEGFEAGTHNLPGIAGLLAGVEFVLARGVDVIGRREREHVAEVARRLAPLPGMAIHGPSFPANRSGLLSFTLAG
MDASSLAFMLDQRFDIAVRAGLHCAPLAHRSLGTYPAGTVRVSPGWFTSNDEIAIFCDAVVKCIP

Sequences:

>Translated_385_residues
MTSRSPLTIYLDNAATSHPKPECVYQAVVHAMRHIGASPGRAGHRRSLEASRLLFQVREAIATLLSVPDSSRIIFTHSAT
EALNLALQGVLLAGDHVVTTSMEHNSLLRPLYQLRRRGVELTIVEAAGDGLVDPDAVRRAFRPTTRMLALGHVSNVCGAI
QPVARLATIAREAGALFLLDAAQSAGSIPIDAAGLGVDLLAAPGHKGLLGPQGTGFLFVAEGVEIRPLLAGGTGSNSSSE
EQPHILPEGFEAGTHNLPGIAGLLAGVEFVLARGVDVIGRREREHVAEVARRLAPLPGMAIHGPSFPANRSGLLSFTLAG
MDASSLAFMLDQRFDIAVRAGLHCAPLAHRSLGTYPAGTVRVSPGWFTSNDEIAIFCDAVVKCIP
>Mature_384_residues
TSRSPLTIYLDNAATSHPKPECVYQAVVHAMRHIGASPGRAGHRRSLEASRLLFQVREAIATLLSVPDSSRIIFTHSATE
ALNLALQGVLLAGDHVVTTSMEHNSLLRPLYQLRRRGVELTIVEAAGDGLVDPDAVRRAFRPTTRMLALGHVSNVCGAIQ
PVARLATIAREAGALFLLDAAQSAGSIPIDAAGLGVDLLAAPGHKGLLGPQGTGFLFVAEGVEIRPLLAGGTGSNSSSEE
QPHILPEGFEAGTHNLPGIAGLLAGVEFVLARGVDVIGRREREHVAEVARRLAPLPGMAIHGPSFPANRSGLLSFTLAGM
DASSLAFMLDQRFDIAVRAGLHCAPLAHRSLGTYPAGTVRVSPGWFTSNDEIAIFCDAVVKCIP

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=402, Percent_Identity=25.8706467661692, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI156713448, Length=298, Percent_Identity=29.5302013422819, Blast_Score=86, Evalue=5e-17,
Organism=Escherichia coli, GI1787970, Length=375, Percent_Identity=32.8, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789175, Length=388, Percent_Identity=31.9587628865979, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI48994898, Length=401, Percent_Identity=28.927680798005, Blast_Score=126, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI25143064, Length=399, Percent_Identity=26.8170426065163, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17533177, Length=343, Percent_Identity=26.8221574344023, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319831, Length=394, Percent_Identity=27.6649746192893, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI20129463, Length=395, Percent_Identity=27.5949367088608, Blast_Score=129, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 40535; Mature: 40404

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRSPLTIYLDNAATSHPKPECVYQAVVHAMRHIGASPGRAGHRRSLEASRLLFQVREA
CCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
IATLLSVPDSSRIIFTHSATEALNLALQGVLLAGDHVVTTSMEHNSLLRPLYQLRRRGVE
HHHHHCCCCCCEEEEEECHHHHHHHHHHHEEEECCEEEEECCCHHHHHHHHHHHHHCCCE
LTIVEAAGDGLVDPDAVRRAFRPTTRMLALGHVSNVCGAIQPVARLATIAREAGALFLLD
EEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
AAQSAGSIPIDAAGLGVDLLAAPGHKGLLGPQGTGFLFVAEGVEIRPLLAGGTGSNSSSE
CCCCCCCCCEECCCCCEEEEECCCCCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCC
EQPHILPEGFEAGTHNLPGIAGLLAGVEFVLARGVDVIGRREREHVAEVARRLAPLPGMA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHCCCCCCE
IHGPSFPANRSGLLSFTLAGMDASSLAFMLDQRFDIAVRAGLHCAPLAHRSLGTYPAGTV
EECCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCHHHCCCCCCHHHHHCCCCCCCCEE
RVSPGWFTSNDEIAIFCDAVVKCIP
EECCCEECCCCCEEEEEHHHHHHCC
>Mature Secondary Structure 
TSRSPLTIYLDNAATSHPKPECVYQAVVHAMRHIGASPGRAGHRRSLEASRLLFQVREA
CCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
IATLLSVPDSSRIIFTHSATEALNLALQGVLLAGDHVVTTSMEHNSLLRPLYQLRRRGVE
HHHHHCCCCCCEEEEEECHHHHHHHHHHHEEEECCEEEEECCCHHHHHHHHHHHHHCCCE
LTIVEAAGDGLVDPDAVRRAFRPTTRMLALGHVSNVCGAIQPVARLATIAREAGALFLLD
EEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
AAQSAGSIPIDAAGLGVDLLAAPGHKGLLGPQGTGFLFVAEGVEIRPLLAGGTGSNSSSE
CCCCCCCCCEECCCCCEEEEECCCCCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCC
EQPHILPEGFEAGTHNLPGIAGLLAGVEFVLARGVDVIGRREREHVAEVARRLAPLPGMA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHCCCCCCE
IHGPSFPANRSGLLSFTLAGMDASSLAFMLDQRFDIAVRAGLHCAPLAHRSLGTYPAGTV
EECCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCHHHCCCCCCHHHHHCCCCCCCCEE
RVSPGWFTSNDEIAIFCDAVVKCIP
EECCCEECCCCCEEEEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]