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The map label for this gene is yoeB [H]

Identifier: 118580860

GI number: 118580860

Start: 2646632

End: 2646892

Strand: Reverse

Name: yoeB [H]

Synonym: Ppro_2447

Alternate gene names: 118580860

Gene position: 2646892-2646632 (Counterclockwise)

Preceding gene: 118580861

Following gene: 118580859

Centisome position: 66.04

GC content: 52.87

Gene sequence:

>261_bases
ATGCCTGACCGACTGGTCTGGACATTCGCAGCCTGGGAAGACTATCAGTACTGGCAGACCCAGGATAAAAAGACGCTGAA
ACGCATCAACCTGCTGATCCGGGATGCCATGCGCAGTCCGTTTGAAGGAATTGGCAAGCCCGAGGCCTTGAGGGAAAATC
TTTCCGGCTTCTGGTCCCGTCGCATTGATGAGACGAATCGTCTGATATACGCTGTGGATGGCATCGATCTGGTCGTGATT
GCCTGTCGTTACCACTATTGA

Upstream 100 bases:

>100_bases
GAGACCGTTCATCTCCTGAAAACACCTGCCAACGCAGCCCACCTTGCCAAATCAATCGAACAGTACCGAGCGGGACAACT
GGTACACGAAAAACTGACCG

Downstream 100 bases:

>100_bases
ATGTGTGAGGTGTCTGATGGGACTATTGGCCGAAAAACGTAACAAATCGATACACTTATGGTTATTACCTGACCCGGGAT
GACGGCCAGCGATGGATCTG

Product: addiction module antitoxin

Products: NA

Alternate protein names: Putative endoribonuclease YoeB; Putative mRNA interferase Yoeb [H]

Number of amino acids: Translated: 86; Mature: 85

Protein sequence:

>86_residues
MPDRLVWTFAAWEDYQYWQTQDKKTLKRINLLIRDAMRSPFEGIGKPEALRENLSGFWSRRIDETNRLIYAVDGIDLVVI
ACRYHY

Sequences:

>Translated_86_residues
MPDRLVWTFAAWEDYQYWQTQDKKTLKRINLLIRDAMRSPFEGIGKPEALRENLSGFWSRRIDETNRLIYAVDGIDLVVI
ACRYHY
>Mature_85_residues
PDRLVWTFAAWEDYQYWQTQDKKTLKRINLLIRDAMRSPFEGIGKPEALRENLSGFWSRRIDETNRLIYAVDGIDLVVIA
CRYHY

Specific function: Part of a toxin-antitoxin (TA) module. It has been proposed to be an mRNA interferase but also an inhibitor of translation initiation. Has an in vitro RNase activity and preferentially cleaves at the 3'-end of purine ribonucleotides. YefM binds to the pro

COG id: COG4115

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the YoeB family [H]

Homologues:

Organism=Escherichia coli, GI87082025, Length=83, Percent_Identity=59.0361445783133, Blast_Score=113, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009614 [H]

Pfam domain/function: PF06769 Plasmid_Txe [H]

EC number: NA

Molecular weight: Translated: 10325; Mature: 10194

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDRLVWTFAAWEDYQYWQTQDKKTLKRINLLIRDAMRSPFEGIGKPEALRENLSGFWSR
CCCCEEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
RIDETNRLIYAVDGIDLVVIACRYHY
HCCCCCCEEEEECCCEEEEEEEECCC
>Mature Secondary Structure 
PDRLVWTFAAWEDYQYWQTQDKKTLKRINLLIRDAMRSPFEGIGKPEALRENLSGFWSR
CCCEEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
RIDETNRLIYAVDGIDLVVIACRYHY
HCCCCCCEEEEECCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]