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The map label for this gene is aroL [H]

Identifier: 118580776

GI number: 118580776

Start: 2554546

End: 2555073

Strand: Reverse

Name: aroL [H]

Synonym: Ppro_2361

Alternate gene names: 118580776

Gene position: 2555073-2554546 (Counterclockwise)

Preceding gene: 118580777

Following gene: 118580773

Centisome position: 63.75

GC content: 67.23

Gene sequence:

>528_bases
ATGACGACAGAGACCATTTTCATAGTCGGGGCCCGCGCCTCGGGAAAGACGACCATCGGACAGAGCCTGGCGCAGGCGCT
GGGTTGCGGGTTTGTTGACACCGATCAGCACATGCTGGAGACGACGTCCCTGACCGTGGCCGAGGTTGTGGAGAAGGAAG
GGTGGGAAGGTTTCCGGCGCCGGGAGAGCGAGGCGCTGCGTGCCGTGACCAGGCCCGGAATGGTGGTGGCCACCGGAGGA
GGGATGGTACTGTCCGAGGCTAACCGCCAGTTCATGCGTGACAACGGAACGGTGCTCTACCTGTCCGCGCCGGCGTCGGT
GCTGGCCGCGCGTCTTGAGGCGAATCCCGAGGAAGCCCAGCGCCCGACGCTCACCGGACGGCCCATCGTGGCAGAGGTGA
GCGAGGTCCTGGCAGCCCGGGAGCCGCTCTACCGGAACGCGGCCCATCATGTGCTGGATGCCACGGCAGCGCCCGATCTC
GTTGTGGCGCAGGCGCTGGAGGCACTGCGCGAGCCGTCGTCACCCTGA

Upstream 100 bases:

>100_bases
AAAAGGTCTTGCGCTGGCCAGCGTTACGGGTGATAGTGTGCAACGGTCGCCCGCCGCACCCAAGGCGGCGGCTTTATTCA
GCAATGGAGAGGGGAGTACC

Downstream 100 bases:

>100_bases
TTGCAACGATCGCGGAGGGCGGATTCGTCCGCCCTCCAGGCAGTCTCAACTCCCGCCTCGCAACGCCTCCACCGCATTCC
CCCCGGCACAGCTCCCTTTT

Product: shikimate kinase II

Products: NA

Alternate protein names: SK 2 [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MTTETIFIVGARASGKTTIGQSLAQALGCGFVDTDQHMLETTSLTVAEVVEKEGWEGFRRRESEALRAVTRPGMVVATGG
GMVLSEANRQFMRDNGTVLYLSAPASVLAARLEANPEEAQRPTLTGRPIVAEVSEVLAAREPLYRNAAHHVLDATAAPDL
VVAQALEALREPSSP

Sequences:

>Translated_175_residues
MTTETIFIVGARASGKTTIGQSLAQALGCGFVDTDQHMLETTSLTVAEVVEKEGWEGFRRRESEALRAVTRPGMVVATGG
GMVLSEANRQFMRDNGTVLYLSAPASVLAARLEANPEEAQRPTLTGRPIVAEVSEVLAAREPLYRNAAHHVLDATAAPDL
VVAQALEALREPSSP
>Mature_174_residues
TTETIFIVGARASGKTTIGQSLAQALGCGFVDTDQHMLETTSLTVAEVVEKEGWEGFRRRESEALRAVTRPGMVVATGGG
MVLSEANRQFMRDNGTVLYLSAPASVLAARLEANPEEAQRPTLTGRPIVAEVSEVLAAREPLYRNAAHHVLDATAAPDLV
VAQALEALREPSSP

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fifth step. [C]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Homo sapiens, GI153792148, Length=170, Percent_Identity=26.4705882352941, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1786587, Length=167, Percent_Identity=53.8922155688623, Blast_Score=187, Evalue=4e-49,
Organism=Escherichia coli, GI87082255, Length=164, Percent_Identity=36.5853658536585, Blast_Score=87, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320332, Length=182, Percent_Identity=30.7692307692308, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 18641; Mature: 18510

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTETIFIVGARASGKTTIGQSLAQALGCGFVDTDQHMLETTSLTVAEVVEKEGWEGFRR
CCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHH
RESEALRAVTRPGMVVATGGGMVLSEANRQFMRDNGTVLYLSAPASVLAARLEANPEEAQ
HHHHHHHHHCCCCEEEEECCCEEEHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCHHHHC
RPTLTGRPIVAEVSEVLAAREPLYRNAAHHVLDATAAPDLVVAQALEALREPSSP
CCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTETIFIVGARASGKTTIGQSLAQALGCGFVDTDQHMLETTSLTVAEVVEKEGWEGFRR
CCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHH
RESEALRAVTRPGMVVATGGGMVLSEANRQFMRDNGTVLYLSAPASVLAARLEANPEEAQ
HHHHHHHHHCCCCEEEEECCCEEEHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCHHHHC
RPTLTGRPIVAEVSEVLAAREPLYRNAAHHVLDATAAPDLVVAQALEALREPSSP
CCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA