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The map label for this gene is algA [H]

Identifier: 118580510

GI number: 118580510

Start: 2253305

End: 2254381

Strand: Reverse

Name: algA [H]

Synonym: Ppro_2094

Alternate gene names: 118580510

Gene position: 2254381-2253305 (Counterclockwise)

Preceding gene: 118580511

Following gene: 118580509

Centisome position: 56.25

GC content: 64.81

Gene sequence:

>1077_bases
GTGTATATCGTCATACTTGCCGGCGGTTCCGGAACCAGGTTCTGGCCACTGTCGCGGACCTCGCGACCCAAACAGCTCAT
CTCCATCTGCGGAGACCGGACCATGCTCCAGCGCACCGTGGAGCGGGTCCTGCCGCTCAAGCCGAAGCGGATCATGATCG
TCACCAACGTGCTCCAGGCCGAGGAGACCAGGCATCAGGTCTCTGGCTACCACGGCGTTCCCATCGACGTGGTGGCCGAA
CCGGTTGCCCGCAACACCGCACCGGCCATAGGACTGGCCGCCACCATCATCGCCGCCCATGATCCGAGGGGAGTGATGGT
GGTGCTGCCGGCCGACCACTTCATCAGGGATGAGGATGCCCTGCGGACTACACTCGTTGCCGCCGGCCACACGGCCAGGA
ACGGCTATCTGGTGACCCTGGGAATCGTGCCCTCCCGCCCTGAGACCGGCTACGGCTACATCGAGGCCGACACTGAGCTG
CGCGGCCAGGGACCCTTTCCGGTGCGGCGCTTCGTGGAAAAGCCGCCCCTGGAGGACGCCCTGCGCTACCTGGATGAGGG
CAGCTATTTCTGGAACAGCGGCATGTTCATCTGGCGCTGCGACACGATCCTGGAGGAGATCGCCACGCATATGCCCGACC
TCTCCTCCCTGCTTACGGAGATCAGCTTCACTGGCGACGTGTGGGAACTGTCCGACCTGCAGAGCCAGATCGGGGAGCTC
TTCCCCAGGGCCGCCAGCATCTCCATCGATTACGGCATCATGGAGCGCTCGGACCGGGTGCAGGTTCTACCGGTGGAGAT
GGGCTGGAGCGACGTGGGGAGTTGGAGCGCCCTGCCTGAGGTGATCGAACCGGATGGGGACGGCACGGTCAGCGTCAACA
CCGCCGGACACATCGCCATCGACTCCAGGGATTGCCTGATCTACGGCGACGGTCGTTTGGTCGCCACCGTCGGGGTCAGC
AACCTGATCGTCGTCTCCACCCCCGATGCCTTGCTGGTCTGCCACCGGGAGCGGGCCCAGGAGGTGAAGAAGGTGGTGGC
GGAACTCTCCGCCAGGGGGATGGAGACGCTCCTGTAG

Upstream 100 bases:

>100_bases
ACCCTCTGGGATGTGCTTGACACCAGCGAAGCCGTAGGCCGCCTGGGTCGCGAAGTGGCCAATTTCCTCGACCGTATCCA
GTACAAATAGGGGGGACAAC

Downstream 100 bases:

>100_bases
CCAGCCCTTTGTCTGTGCGCCCCGTACCGACCGCTGACGCGGAAGGTGTCCGGGGCGCTGATCAGAAAAACCGGAAATGC
TGGTTGAGGGCCGCCTGATT

Product: mannose-1-phosphate guanylyltransferase

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; GMP; GMPP; GTP--mannose-1-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MYIVILAGGSGTRFWPLSRTSRPKQLISICGDRTMLQRTVERVLPLKPKRIMIVTNVLQAEETRHQVSGYHGVPIDVVAE
PVARNTAPAIGLAATIIAAHDPRGVMVVLPADHFIRDEDALRTTLVAAGHTARNGYLVTLGIVPSRPETGYGYIEADTEL
RGQGPFPVRRFVEKPPLEDALRYLDEGSYFWNSGMFIWRCDTILEEIATHMPDLSSLLTEISFTGDVWELSDLQSQIGEL
FPRAASISIDYGIMERSDRVQVLPVEMGWSDVGSWSALPEVIEPDGDGTVSVNTAGHIAIDSRDCLIYGDGRLVATVGVS
NLIVVSTPDALLVCHRERAQEVKKVVAELSARGMETLL

Sequences:

>Translated_358_residues
MYIVILAGGSGTRFWPLSRTSRPKQLISICGDRTMLQRTVERVLPLKPKRIMIVTNVLQAEETRHQVSGYHGVPIDVVAE
PVARNTAPAIGLAATIIAAHDPRGVMVVLPADHFIRDEDALRTTLVAAGHTARNGYLVTLGIVPSRPETGYGYIEADTEL
RGQGPFPVRRFVEKPPLEDALRYLDEGSYFWNSGMFIWRCDTILEEIATHMPDLSSLLTEISFTGDVWELSDLQSQIGEL
FPRAASISIDYGIMERSDRVQVLPVEMGWSDVGSWSALPEVIEPDGDGTVSVNTAGHIAIDSRDCLIYGDGRLVATVGVS
NLIVVSTPDALLVCHRERAQEVKKVVAELSARGMETLL
>Mature_358_residues
MYIVILAGGSGTRFWPLSRTSRPKQLISICGDRTMLQRTVERVLPLKPKRIMIVTNVLQAEETRHQVSGYHGVPIDVVAE
PVARNTAPAIGLAATIIAAHDPRGVMVVLPADHFIRDEDALRTTLVAAGHTARNGYLVTLGIVPSRPETGYGYIEADTEL
RGQGPFPVRRFVEKPPLEDALRYLDEGSYFWNSGMFIWRCDTILEEIATHMPDLSSLLTEISFTGDVWELSDLQSQIGEL
FPRAASISIDYGIMERSDRVQVLPVEMGWSDVGSWSALPEVIEPDGDGTVSVNTAGHIAIDSRDCLIYGDGRLVATVGVS
NLIVVSTPDALLVCHRERAQEVKKVVAELSARGMETLL

Specific function: Produces a precursor for alginate polymerization. The alginate layer provides a protective barrier against host immune defenses and antibiotics [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=358, Percent_Identity=40.5027932960894, Blast_Score=232, Evalue=2e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 39286; Mature: 39286

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIVILAGGSGTRFWPLSRTSRPKQLISICGDRTMLQRTVERVLPLKPKRIMIVTNVLQA
CEEEEEECCCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEEHHHHH
EETRHQVSGYHGVPIDVVAEPVARNTAPAIGLAATIIAAHDPRGVMVVLPADHFIRDEDA
HHHHHHHCCCCCCCHHHHCCCHHCCCCCHHHHEEEEEEECCCCCEEEEECCCHHCCCCHH
LRTTLVAAGHTARNGYLVTLGIVPSRPETGYGYIEADTELRGQGPFPVRRFVEKPPLEDA
HHHHHEECCCCCCCCEEEEEEEECCCCCCCCEEEEECCCCCCCCCCHHHHHHCCCCHHHH
LRYLDEGSYFWNSGMFIWRCDTILEEIATHMPDLSSLLTEISFTGDVWELSDLQSQIGEL
HHHHHCCCEEEECCEEEEEHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEHHHHHHHHHHH
FPRAASISIDYGIMERSDRVQVLPVEMGWSDVGSWSALPEVIEPDGDGTVSVNTAGHIAI
CCCCEEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCHHCCCCCCCEEEEECCEEEEE
DSRDCLIYGDGRLVATVGVSNLIVVSTPDALLVCHRERAQEVKKVVAELSARGMETLL
CCCCEEEEECCEEEEEECCCEEEEEECCCCEEEECHHHHHHHHHHHHHHHHCCHHHCC
>Mature Secondary Structure
MYIVILAGGSGTRFWPLSRTSRPKQLISICGDRTMLQRTVERVLPLKPKRIMIVTNVLQA
CEEEEEECCCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEEHHHHH
EETRHQVSGYHGVPIDVVAEPVARNTAPAIGLAATIIAAHDPRGVMVVLPADHFIRDEDA
HHHHHHHCCCCCCCHHHHCCCHHCCCCCHHHHEEEEEEECCCCCEEEEECCCHHCCCCHH
LRTTLVAAGHTARNGYLVTLGIVPSRPETGYGYIEADTELRGQGPFPVRRFVEKPPLEDA
HHHHHEECCCCCCCCEEEEEEEECCCCCCCCEEEEECCCCCCCCCCHHHHHHCCCCHHHH
LRYLDEGSYFWNSGMFIWRCDTILEEIATHMPDLSSLLTEISFTGDVWELSDLQSQIGEL
HHHHHCCCEEEECCEEEEEHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEHHHHHHHHHHH
FPRAASISIDYGIMERSDRVQVLPVEMGWSDVGSWSALPEVIEPDGDGTVSVNTAGHIAI
CCCCEEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCHHCCCCCCCEEEEECCEEEEE
DSRDCLIYGDGRLVATVGVSNLIVVSTPDALLVCHRERAQEVKKVVAELSARGMETLL
CCCCEEEEECCEEEEEECCCEEEEEECCCCEEEECHHHHHHHHHHHHHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]