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The map label for this gene is frr

Identifier: 118580463

GI number: 118580463

Start: 2196635

End: 2197192

Strand: Direct

Name: frr

Synonym: Ppro_2047

Alternate gene names: 118580463

Gene position: 2196635-2197192 (Clockwise)

Preceding gene: 118580462

Following gene: 118580464

Centisome position: 54.81

GC content: 56.09

Gene sequence:

>558_bases
ATGCCCAAAACCGTACTCAGCGACATGAAAACCCATATGGAAAAGACCGTCGCGGTTCTCAAGGCCGAATTCCAGAAGGT
CCGCACCGGCCGCGCCTCCACCGCCATCCTGGACAGCGTCAAGATGGACTACTACGGCAACCCCACCCCCATCAGCCAGA
TAGCCACCCTGGCCATTCCCGAGCCGCGCATGATTACCATCACCCCCTGGGAGGCCAAACAGATTTCAGTCATTGAAAAG
GCCATCTTCAACGCCAACATCGGCCTTACCCCCTCCAACGACGGCAAGAGCATCCGCCTCAGTCTCCCCCCCCTGACCGA
AGAGCGGCGCCGGGAGATCGTCAAGGATTTGAAGAAGATGGCCGAGGACAACAGGGTCGCCCTGCGCAATATCCGCCGCG
ACGCCATCGACCGCCTGAAAAAGCTGGAAAAGGATAAGAGCATCACCGAGGACGAGCTGAAGAAGTATGAAAAAGAGGTT
CAGGACAACACCAAGAGCTTCGAGATCAAAATCGACGAGGCAATGACCAACAAGGAAAAAGAGGTCATGGAGGTTTGA

Upstream 100 bases:

>100_bases
AACCTGCCGATCATCGTCTTCGATCTGACAACCGAGGGCAACATCATCAAGGTTATCAACGGCGAAGAGATCGGCACCAT
CGTACAAGGAGAATGACCCC

Downstream 100 bases:

>100_bases
TGCGCGAGCTCGACCCTGAACGGCTCCCCGTCCATCTGGCAATCATCATGGATGGCAACGGACGCTGGGCCCAGCAGCGC
ATGCTCAAACGCATCGTCGG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MPKTVLSDMKTHMEKTVAVLKAEFQKVRTGRASTAILDSVKMDYYGNPTPISQIATLAIPEPRMITITPWEAKQISVIEK
AIFNANIGLTPSNDGKSIRLSLPPLTEERRREIVKDLKKMAEDNRVALRNIRRDAIDRLKKLEKDKSITEDELKKYEKEV
QDNTKSFEIKIDEAMTNKEKEVMEV

Sequences:

>Translated_185_residues
MPKTVLSDMKTHMEKTVAVLKAEFQKVRTGRASTAILDSVKMDYYGNPTPISQIATLAIPEPRMITITPWEAKQISVIEK
AIFNANIGLTPSNDGKSIRLSLPPLTEERRREIVKDLKKMAEDNRVALRNIRRDAIDRLKKLEKDKSITEDELKKYEKEV
QDNTKSFEIKIDEAMTNKEKEVMEV
>Mature_184_residues
PKTVLSDMKTHMEKTVAVLKAEFQKVRTGRASTAILDSVKMDYYGNPTPISQIATLAIPEPRMITITPWEAKQISVIEKA
IFNANIGLTPSNDGKSIRLSLPPLTEERRREIVKDLKKMAEDNRVALRNIRRDAIDRLKKLEKDKSITEDELKKYEKEVQ
DNTKSFEIKIDEAMTNKEKEVMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Escherichia coli, GI1786368, Length=177, Percent_Identity=41.8079096045198, Blast_Score=153, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6321827, Length=188, Percent_Identity=23.936170212766, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_PELPD (A1AQN5)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_901713.1
- ProteinModelPortal:   A1AQN5
- SMR:   A1AQN5
- STRING:   A1AQN5
- GeneID:   4574244
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_2047
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   A1AQN5
- ProtClustDB:   PRK00083
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 21202; Mature: 21071

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKTVLSDMKTHMEKTVAVLKAEFQKVRTGRASTAILDSVKMDYYGNPTPISQIATLAIP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCC
EPRMITITPWEAKQISVIEKAIFNANIGLTPSNDGKSIRLSLPPLTEERRREIVKDLKKM
CCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHH
AEDNRVALRNIRRDAIDRLKKLEKDKSITEDELKKYEKEVQDNTKSFEIKIDEAMTNKEK
HCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEEHHHHCCCHH
EVMEV
HHHCC
>Mature Secondary Structure 
PKTVLSDMKTHMEKTVAVLKAEFQKVRTGRASTAILDSVKMDYYGNPTPISQIATLAIP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCC
EPRMITITPWEAKQISVIEKAIFNANIGLTPSNDGKSIRLSLPPLTEERRREIVKDLKKM
CCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHH
AEDNRVALRNIRRDAIDRLKKLEKDKSITEDELKKYEKEVQDNTKSFEIKIDEAMTNKEK
HCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEEHHHHCCCHH
EVMEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA