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The map label for this gene is appC [H]

Identifier: 118580429

GI number: 118580429

Start: 2162313

End: 2163170

Strand: Reverse

Name: appC [H]

Synonym: Ppro_2013

Alternate gene names: 118580429

Gene position: 2163170-2162313 (Counterclockwise)

Preceding gene: 118580430

Following gene: 118580428

Centisome position: 53.97

GC content: 64.69

Gene sequence:

>858_bases
ATGACCGACCTGACCAGTTCATACCTGTACGCCGTTGTCTGGCAACGCCTGAAACGCAACCGCCTGGCCCTGGCCGGCGG
CTGCGTGGTGCTGCTGCTCTTCGTCGTCTCCCTGCTGGCCCCGTTGATCGTCCCCTCCGACCCCAACGCCATCGATGCCT
GGCATGTGCTCTCCCCCCCCTCCTGGCAGCACTGGTTCGGCACCGACGAACTGGGGCGCGACGTACTCAGTCGCATGATC
TATGGCAGCCGCATCTCCCTCAAGGTCGGCTTTGTCGCCGTGGGCATCGCCGTCTCCATCGGCACCCTGGTGGGACTGGT
CTCCGGCTACTACCGTGGCCTGGTTGACAGCTGCCTGATGCGCATGGTGGACATCATGCTCTGCTTTCCCGCCTTCTTCC
TGATCCTGGCGGTGATCACCTTTCTGGAGCCTTCCATCTGGTACATCATGATGGTCATCGGTCTGACCGGCTGGATGGGG
GTGGCGCGCATGGTGCGGGCCGAGACCCTCTCCATCCGCGAGATGGACTACATCACGGCGGCCCGCTGCATCGGCTGCTC
CGACCTGCGGATCATCTTCCGCCACATCCTGCCCAACACCCTGTCGCCGGTGCTGGTTTCCGCCACCCTGGGGGTGGCCG
GCGCCATCCTGACCGAGTCGGCCCTCTCGTTCCTGGGCATCGGCGTCCAGCCCCCCACCCCCAGCTGGGGCAACATCCTC
ACCTCGGGCAAGGACTACATCGAATTTGCCTGGTGGCTCTCCTTCTTCCCCGGTCTGGCCATCCTGGTGACGGTACTGGC
CTACAACCTGCTGGGGGAGGGGATCAGGGACGCCTTCGATCCCCGGGTGAACCGTTGA

Upstream 100 bases:

>100_bases
TGGTGATCGGCGCCTTTTTGACCCTGATCGGTAACCTGGTGGCCGATGTCAGCTACGCCCTGGCCGATCCGCGCATCCGG
CACGGGGCATAGGGGCGCCC

Downstream 100 bases:

>100_bases
CAGCCGTGGACATCCGGCGCATACACCCCCTGAACAGGCGGGAAGGGCAGGACGGCCCGGTGGTTTACTGGATGAGCCGA
GACCAGAGGGCAATGGACAA

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MTDLTSSYLYAVVWQRLKRNRLALAGGCVVLLLFVVSLLAPLIVPSDPNAIDAWHVLSPPSWQHWFGTDELGRDVLSRMI
YGSRISLKVGFVAVGIAVSIGTLVGLVSGYYRGLVDSCLMRMVDIMLCFPAFFLILAVITFLEPSIWYIMMVIGLTGWMG
VARMVRAETLSIREMDYITAARCIGCSDLRIIFRHILPNTLSPVLVSATLGVAGAILTESALSFLGIGVQPPTPSWGNIL
TSGKDYIEFAWWLSFFPGLAILVTVLAYNLLGEGIRDAFDPRVNR

Sequences:

>Translated_285_residues
MTDLTSSYLYAVVWQRLKRNRLALAGGCVVLLLFVVSLLAPLIVPSDPNAIDAWHVLSPPSWQHWFGTDELGRDVLSRMI
YGSRISLKVGFVAVGIAVSIGTLVGLVSGYYRGLVDSCLMRMVDIMLCFPAFFLILAVITFLEPSIWYIMMVIGLTGWMG
VARMVRAETLSIREMDYITAARCIGCSDLRIIFRHILPNTLSPVLVSATLGVAGAILTESALSFLGIGVQPPTPSWGNIL
TSGKDYIEFAWWLSFFPGLAILVTVLAYNLLGEGIRDAFDPRVNR
>Mature_284_residues
TDLTSSYLYAVVWQRLKRNRLALAGGCVVLLLFVVSLLAPLIVPSDPNAIDAWHVLSPPSWQHWFGTDELGRDVLSRMIY
GSRISLKVGFVAVGIAVSIGTLVGLVSGYYRGLVDSCLMRMVDIMLCFPAFFLILAVITFLEPSIWYIMMVIGLTGWMGV
ARMVRAETLSIREMDYITAARCIGCSDLRIIFRHILPNTLSPVLVSATLGVAGAILTESALSFLGIGVQPPTPSWGNILT
SGKDYIEFAWWLSFFPGLAILVTVLAYNLLGEGIRDAFDPRVNR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=272, Percent_Identity=42.2794117647059, Blast_Score=234, Evalue=5e-63,
Organism=Escherichia coli, GI1787760, Length=271, Percent_Identity=40.2214022140221, Blast_Score=216, Evalue=1e-57,
Organism=Escherichia coli, GI1789964, Length=278, Percent_Identity=42.4460431654676, Blast_Score=207, Evalue=8e-55,
Organism=Escherichia coli, GI1787498, Length=276, Percent_Identity=41.6666666666667, Blast_Score=184, Evalue=8e-48,
Organism=Escherichia coli, GI1788505, Length=226, Percent_Identity=39.3805309734513, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1789889, Length=240, Percent_Identity=34.5833333333333, Blast_Score=157, Evalue=5e-40,
Organism=Escherichia coli, GI1787549, Length=244, Percent_Identity=34.8360655737705, Blast_Score=131, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31351; Mature: 31219

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLTSSYLYAVVWQRLKRNRLALAGGCVVLLLFVVSLLAPLIVPSDPNAIDAWHVLSPP
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCC
SWQHWFGTDELGRDVLSRMIYGSRISLKVGFVAVGIAVSIGTLVGLVSGYYRGLVDSCLM
CCCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMVDIMLCFPAFFLILAVITFLEPSIWYIMMVIGLTGWMGVARMVRAETLSIREMDYITA
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARCIGCSDLRIIFRHILPNTLSPVLVSATLGVAGAILTESALSFLGIGVQPPTPSWGNIL
HHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
TSGKDYIEFAWWLSFFPGLAILVTVLAYNLLGEGIRDAFDPRVNR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TDLTSSYLYAVVWQRLKRNRLALAGGCVVLLLFVVSLLAPLIVPSDPNAIDAWHVLSPP
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCC
SWQHWFGTDELGRDVLSRMIYGSRISLKVGFVAVGIAVSIGTLVGLVSGYYRGLVDSCLM
CCCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMVDIMLCFPAFFLILAVITFLEPSIWYIMMVIGLTGWMGVARMVRAETLSIREMDYITA
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARCIGCSDLRIIFRHILPNTLSPVLVSATLGVAGAILTESALSFLGIGVQPPTPSWGNIL
HHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
TSGKDYIEFAWWLSFFPGLAILVTVLAYNLLGEGIRDAFDPRVNR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]