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The map label for this gene is hupB [H]

Identifier: 118580311

GI number: 118580311

Start: 2043474

End: 2043854

Strand: Direct

Name: hupB [H]

Synonym: Ppro_1893

Alternate gene names: 118580311

Gene position: 2043474-2043854 (Clockwise)

Preceding gene: 118580310

Following gene: 118580319

Centisome position: 50.98

GC content: 44.88

Gene sequence:

>381_bases
ATGAACAAAACAGAACTCGTTGCGAAAATTGCAGAAGGTGCTGAATTGACCAAGGTACAAGCAGAAAAGGTGCTCGATAT
TTTCATTGCTTCAACCACTGCCGCTCTCAAAGCCGGTGATAAAGTTGCGATCATCGGTTTTGGTGCATTCAGCGCGGTGA
CCCGTAAAGCACGCACCGGCAGGAATCCACAGACCGGCAAGGCACTGCAAATCGCCGAAAAGACAAATGGTAAATTCACA
CCAGGTAAAGCACTTAAGGATTTAACGGCTAAACCGGTCAAATCGAAATCTGCTAAACCGACCAAATTGGAATCAGCAAA
ACCAATTAAGTTGGAGTCTGCAAAACCAACCAAGTTGAAATCGGCAATAAAGAAGAAGTAG

Upstream 100 bases:

>100_bases
GATCAGGAAAAGAAACCAGATGTAGAAGAAGTCTCGTAAAGTATGAATTGTGAACAATAGCGTTATCAGTATATAACCAC
AAAAACACCAAGGAGGGGTT

Downstream 100 bases:

>100_bases
AATCAGCCGATTGCGGTCAATGGTCCTGGCGTAATTGTCTGCACTGATTACGCCAGGACCATTTCATTCTCACCATTTAT
TTCATATAATTTATTACTAT

Product: histone family protein DNA-binding protein

Products: NA

Alternate protein names: HU-1; NS1 [H]

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MNKTELVAKIAEGAELTKVQAEKVLDIFIASTTAALKAGDKVAIIGFGAFSAVTRKARTGRNPQTGKALQIAEKTNGKFT
PGKALKDLTAKPVKSKSAKPTKLESAKPIKLESAKPTKLKSAIKKK

Sequences:

>Translated_126_residues
MNKTELVAKIAEGAELTKVQAEKVLDIFIASTTAALKAGDKVAIIGFGAFSAVTRKARTGRNPQTGKALQIAEKTNGKFT
PGKALKDLTAKPVKSKSAKPTKLESAKPIKLESAKPTKLKSAIKKK
>Mature_126_residues
MNKTELVAKIAEGAELTKVQAEKVLDIFIASTTAALKAGDKVAIIGFGAFSAVTRKARTGRNPQTGKALQIAEKTNGKFT
PGKALKDLTAKPVKSKSAKPTKLESAKPIKLESAKPTKLKSAIKKK

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=87, Percent_Identity=55.1724137931034, Blast_Score=94, Evalue=3e-21,
Organism=Escherichia coli, GI1790433, Length=87, Percent_Identity=52.8735632183908, Blast_Score=88, Evalue=2e-19,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 13302; Mature: 13302

Theoretical pI: Translated: 11.12; Mature: 11.12

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTELVAKIAEGAELTKVQAEKVLDIFIASTTAALKAGDKVAIIGFGAFSAVTRKARTG
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCC
RNPQTGKALQIAEKTNGKFTPGKALKDLTAKPVKSKSAKPTKLESAKPIKLESAKPTKLK
CCCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHH
SAIKKK
HHHCCC
>Mature Secondary Structure
MNKTELVAKIAEGAELTKVQAEKVLDIFIASTTAALKAGDKVAIIGFGAFSAVTRKARTG
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCC
RNPQTGKALQIAEKTNGKFTPGKALKDLTAKPVKSKSAKPTKLESAKPIKLESAKPTKLK
CCCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHH
SAIKKK
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550432 [H]