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The map label for this gene is engA

Identifier: 118580147

GI number: 118580147

Start: 1856064

End: 1857410

Strand: Direct

Name: engA

Synonym: Ppro_1727

Alternate gene names: 118580147

Gene position: 1856064-1857410 (Clockwise)

Preceding gene: 118580146

Following gene: 118580148

Centisome position: 46.31

GC content: 61.77

Gene sequence:

>1347_bases
ATGAAACCTCTCGTCGCCCTGGTGGGCCGTCCCAATGTGGGCAAATCAACCCTGTTCAACCGTCTCTTGGGCCATCGCCG
CGCCATTGTGGACGATACCCCCGGCGTCACCCGTGACCGCAACTACGCCCTGATCAATCGCTTCGAGAAGCCGTTCATCC
TGATCGACACCGGCGGGTTCGAGCCGGTTACCGAAGACCGGCTGCTGCAGCAGATGCGCGAGCAGTCCAGCCTGGCCATG
GAAGAGGCCGACGTGATCATCTTCATGATGGACGCCCGCAGCGGCCTGACGCCGGCCGACGTGGAGGTGGCTAACATGCT
GCGCCGCGTCAAGAAGCCGGTCATGTACGTGGTCAACAAGGTGGATGGCGAGAAGCTGGAGAACGATTCCGCCGAGTTCT
ACTCCCTGGGGGTGGAGAACCTGTACACCATCTCTGCTGAGCACAACCGCGGCGTGTACGACCTGATGGATGACCTGCTG
GAACTGCTGCCCCTGGACAGCGGCCCCGAATCCGGCGAAGAGATCACCCGCATCGCGGTGGTCGGGCGCCCCAACGTGGG
CAAATCATCCCTGGTCAACCGCCTGTTGGGGTTCGAGCGGGTGGTGGCCAATCCCACTGCCGGCACGACCCGCGATTCCG
TCGACACGCTGTTCATGTGCAACAAGAAGCCGTACCTGCTGATCGACACCGCCGGCATCCGCCGCAAGGGGAAGACCACC
GAGAAACTGGAGAAGTACAGCGTGGTGGATGCCCTGCGCAGCATCGAGCGGGCCGATGTGGTGCTGGTGGTGCTGGACGC
CACCCAGGGGGTGACGGAGCAGGACGAGCGCATCGCCGGATACGTGCACGAGGCGGGCAGGGCGTGTGTGTTCGTGCTCA
ACAAGTGGGACGCCATCGAAAAGGACAACAGCACCTTCGGCCTGTACGTGGACAAGGTCAGGACCGGTTTTAAGTACCTG
GCCTATGCGCCCATCGTCTTTGTTTCGGCCATGACCGGCCAGCGCACCGCCAAGGTCATGGAATCGGTGGACGAGGTCAT
GGAGCAGTTCAGCCGCAGGGTGACCACCTCCGACCTGAACCGCGTCTTCTCCGAAGCCACCAGTTCCCACCATGCGCCGC
TGGCCCATGGCCGGCGGGTAAAGTTCTATTTCGCCACCCAGGTAACCACCCGCCCTCCCTGCTTCGTCGTCTTCACCAAT
CAGCCTGACAGCATCCACTTCTCCTACGAGCGCTACCTGATCAACCAGTTCAGAGAGGCCTTCGGTTTCAACGGCACCCC
CTTGAGGATCATTTTCAGGGGGAGGGAGAAAAACAGCCCCTCACGCAGGCCTGTTAAGGATTCATAA

Upstream 100 bases:

>100_bases
CTGGAGCGAGCGCACCTCGAAACTGAGAGAGTTCGGCTACGAGTAGGGAACTGCTTGAGATCGGCGGCCATTTAAGAGTT
CAACCCCTGGAAGGAAACAC

Downstream 100 bases:

>100_bases
GACTTTACTTGCCCGATTCGATGGGATATATTTTCGGCATTTATCTTCTCAATCACACGTGAAACGGGGCAGCGGGGCAT
GAGTCTTGTCGGAAACCTGG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MKPLVALVGRPNVGKSTLFNRLLGHRRAIVDDTPGVTRDRNYALINRFEKPFILIDTGGFEPVTEDRLLQQMREQSSLAM
EEADVIIFMMDARSGLTPADVEVANMLRRVKKPVMYVVNKVDGEKLENDSAEFYSLGVENLYTISAEHNRGVYDLMDDLL
ELLPLDSGPESGEEITRIAVVGRPNVGKSSLVNRLLGFERVVANPTAGTTRDSVDTLFMCNKKPYLLIDTAGIRRKGKTT
EKLEKYSVVDALRSIERADVVLVVLDATQGVTEQDERIAGYVHEAGRACVFVLNKWDAIEKDNSTFGLYVDKVRTGFKYL
AYAPIVFVSAMTGQRTAKVMESVDEVMEQFSRRVTTSDLNRVFSEATSSHHAPLAHGRRVKFYFATQVTTRPPCFVVFTN
QPDSIHFSYERYLINQFREAFGFNGTPLRIIFRGREKNSPSRRPVKDS

Sequences:

>Translated_448_residues
MKPLVALVGRPNVGKSTLFNRLLGHRRAIVDDTPGVTRDRNYALINRFEKPFILIDTGGFEPVTEDRLLQQMREQSSLAM
EEADVIIFMMDARSGLTPADVEVANMLRRVKKPVMYVVNKVDGEKLENDSAEFYSLGVENLYTISAEHNRGVYDLMDDLL
ELLPLDSGPESGEEITRIAVVGRPNVGKSSLVNRLLGFERVVANPTAGTTRDSVDTLFMCNKKPYLLIDTAGIRRKGKTT
EKLEKYSVVDALRSIERADVVLVVLDATQGVTEQDERIAGYVHEAGRACVFVLNKWDAIEKDNSTFGLYVDKVRTGFKYL
AYAPIVFVSAMTGQRTAKVMESVDEVMEQFSRRVTTSDLNRVFSEATSSHHAPLAHGRRVKFYFATQVTTRPPCFVVFTN
QPDSIHFSYERYLINQFREAFGFNGTPLRIIFRGREKNSPSRRPVKDS
>Mature_448_residues
MKPLVALVGRPNVGKSTLFNRLLGHRRAIVDDTPGVTRDRNYALINRFEKPFILIDTGGFEPVTEDRLLQQMREQSSLAM
EEADVIIFMMDARSGLTPADVEVANMLRRVKKPVMYVVNKVDGEKLENDSAEFYSLGVENLYTISAEHNRGVYDLMDDLL
ELLPLDSGPESGEEITRIAVVGRPNVGKSSLVNRLLGFERVVANPTAGTTRDSVDTLFMCNKKPYLLIDTAGIRRKGKTT
EKLEKYSVVDALRSIERADVVLVVLDATQGVTEQDERIAGYVHEAGRACVFVLNKWDAIEKDNSTFGLYVDKVRTGFKYL
AYAPIVFVSAMTGQRTAKVMESVDEVMEQFSRRVTTSDLNRVFSEATSSHHAPLAHGRRVKFYFATQVTTRPPCFVVFTN
QPDSIHFSYERYLINQFREAFGFNGTPLRIIFRGREKNSPSRRPVKDS

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=471, Percent_Identity=42.4628450106157, Blast_Score=356, Evalue=1e-99,
Organism=Escherichia coli, GI1788919, Length=119, Percent_Identity=36.1344537815126, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI2367268, Length=95, Percent_Identity=38.9473684210526, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17507259, Length=120, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=179, Percent_Identity=30.1675977653631, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_PELPD (A1APR9)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_901397.1
- ProteinModelPortal:   A1APR9
- SMR:   A1APR9
- STRING:   A1APR9
- GeneID:   4572828
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_1727
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   KCEKAFD
- PhylomeDB:   A1APR9
- ProtClustDB:   PRK00093
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 50482; Mature: 50482

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLVALVGRPNVGKSTLFNRLLGHRRAIVDDTPGVTRDRNYALINRFEKPFILIDTGGF
CCCCEEECCCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHCCCCCEEEEECCCC
EPVTEDRLLQQMREQSSLAMEEADVIIFMMDARSGLTPADVEVANMLRRVKKPVMYVVNK
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VDGEKLENDSAEFYSLGVENLYTISAEHNRGVYDLMDDLLELLPLDSGPESGEEITRIAV
CCCCCCCCCCHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
VGRPNVGKSSLVNRLLGFERVVANPTAGTTRDSVDTLFMCNKKPYLLIDTAGIRRKGKTT
ECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCH
EKLEKYSVVDALRSIERADVVLVVLDATQGVTEQDERIAGYVHEAGRACVFVLNKWDAIE
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCC
KDNSTFGLYVDKVRTGFKYLAYAPIVFVSAMTGQRTAKVMESVDEVMEQFSRRVTTSDLN
CCCCEEEEEHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
RVFSEATSSHHAPLAHGRRVKFYFATQVTTRPPCFVVFTNQPDSIHFSYERYLINQFREA
HHHHHHHCCCCCCCCCCCEEEEEEEEEECCCCCEEEEECCCCCCEEEHHHHHHHHHHHHH
FGFNGTPLRIIFRGREKNSPSRRPVKDS
HCCCCCCEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MKPLVALVGRPNVGKSTLFNRLLGHRRAIVDDTPGVTRDRNYALINRFEKPFILIDTGGF
CCCCEEECCCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHCCCCCEEEEECCCC
EPVTEDRLLQQMREQSSLAMEEADVIIFMMDARSGLTPADVEVANMLRRVKKPVMYVVNK
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VDGEKLENDSAEFYSLGVENLYTISAEHNRGVYDLMDDLLELLPLDSGPESGEEITRIAV
CCCCCCCCCCHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
VGRPNVGKSSLVNRLLGFERVVANPTAGTTRDSVDTLFMCNKKPYLLIDTAGIRRKGKTT
ECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCH
EKLEKYSVVDALRSIERADVVLVVLDATQGVTEQDERIAGYVHEAGRACVFVLNKWDAIE
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCC
KDNSTFGLYVDKVRTGFKYLAYAPIVFVSAMTGQRTAKVMESVDEVMEQFSRRVTTSDLN
CCCCEEEEEHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
RVFSEATSSHHAPLAHGRRVKFYFATQVTTRPPCFVVFTNQPDSIHFSYERYLINQFREA
HHHHHHHCCCCCCCCCCCEEEEEEEEEECCCCCEEEEECCCCCCEEEHHHHHHHHHHHHH
FGFNGTPLRIIFRGREKNSPSRRPVKDS
HCCCCCCEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA