| Definition | Pelobacter propionicus DSM 2379 chromosome, complete genome. |
|---|---|
| Accession | NC_008609 |
| Length | 4,008,000 |
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The map label for this gene is acnB [H]
Identifier: 118580113
GI number: 118580113
Start: 1817961
End: 1820495
Strand: Direct
Name: acnB [H]
Synonym: Ppro_1692
Alternate gene names: 118580113
Gene position: 1817961-1820495 (Clockwise)
Preceding gene: 118580112
Following gene: 118580114
Centisome position: 45.36
GC content: 64.58
Gene sequence:
>2535_bases ATGATCCAAGAGTACCTGCACCACGAGCAGGAACGGGCCCGGCAGGGCATACCGCCACTCCCGCTGTCGGCTGAGCAGAC CGCCCGGCTCTGTGCCCTGCTGACAGCCCCGCCGTCTGGTCGGGAAGAGTTCCTGCTGACCCTGCTTGAAAGACGCGTTC CCCCCGGCGTTGACCCGGCCGCCAAGGTCAAGGCCGGTTTCCTGACCAATATTGTCTCCGGCGCTCTACAATCTCCGTTG CTCACTCCGTTTGACGCCATCCGCATTCTGGGCGGCATGCTGGGTGGGTACAATGTGGCGCCCCTGGTGGCCGCCCTTTC CGATCCAGAACTTGTCGGCGAAGCTGCCGATCAGTTGAGCCGCATCACCCTGGTCCATGGAGCCTTCGACCAGGTGGCTG CCTTGGTCAGGGAGGGGAACCAGGCAGCTTCCCGGGTGATGCGTTCCTGGGCCGAGGGGGAATGGTTCACCCGCCGCGCG CCTCTCCCCGCAACCATCAGGCTCAAGGTCTACCGGGTGCAAGGGGAAATTAACACGGACGATTTTTCCCCGGCCGGCGA CGCCTGGAGTCGTCCCGACATTCCGCTACATGCCCTGGTCATGGGCAGGCGCCGCTTCCCCGACGGTCTGGCCACCATGG CCGCCTTCCGTGAAGAGGGATGCCGGATAGCCTTCGTAGGGGACGTGATAGGCACCGGGTCTTCCCGAAAATCGGCCTGC AACAGCCTGCTCTGGGCCATCGGCGAGGATATCCCCGGCGTGCCCAACAAGAGGGGAGGGGGCGTGATCATCGGCGGCGT CATCGCACCGATTTTCTTCAACACCGCCCAGGATTCCGGCGCCCTGCCGATCAGGGCAGAGGTCGGGGCGCTCTCCACCG GTGACCTCATCGTGGTGGACACCGTCCGGGGGATCATCTCCGATGAACAGGGAGCGAACGTTCTCTCCCGCTTCAGCCTT GCCCCCGCGACCCTGGCGGACGAATTCCGGGCCGGAGGCCGCATCCCGCTGATTATCGGCCGTGCCCTGACCGACAGGGC CCGTTCCTTCCTTGGTCTGCCCGGCTCCACGCTCTTCACCCTGCCGGACAATCCGGTGCCCGAACCGGGGCAGGGGTTTA CCCTGGCCCAGAAGATGGTCGGCGCCGCCTGCGGCGTCGGGGGCGTCCTGCCCGGCAGTGCCTGCCAGCCGGTCATGACC ACTGTGGGGAGCCAGGACACCACCGGCCCCATGACCGCCGACGAACTAAAGGAGTTGGCCTGCTTAAGCTTCCAGGCTCC CCTGGTCATGCAGTCTTTCTGCCACACAGCCGCCTATCCCAAGCTGTCCGACCTGGCGATGCACCGCACGCTCCCCTCGT TCATCACCCAGCGTGGAGGCGTTTCCCTGCGGCCCGGCGACGGGGTTATCCACTCCTGGCTGAACCGTCTGCTGCTGCCG GACAGGGTTGGCACCGGAGGCGACTCCCACACCCGCTTCCCCCTGGGCATATCCTTTCCGGCCGGTTCCGGTCTGGTGGC TTTTGCGGCCGCCATGGGCTTCATGCCGCTGGACATGCCCGAATCGGTATTGGTGCGCTTCAGCGGCAGCCTGAACAGCG GCATCACCCTGCGTGACGCGGTAAACGCCATTCCCCTCCAGGCCATACGGGAGGGGCTTCTGACCGTGCCCAAGCAGAAC AAGGTCAACATCTTCAGCGGACGCATCCTGGAGATGGAGGGGATTTCCGACCTGAGTGTGGAGCAGGCCTTCGAGCTGAC CGATTCCGCCGCGGAGCGTTCCGCTGCCGCCGGCTGCATCCAGCTCTCGGAAGAGCGTGTCGCAGAATTCCTCCGCTCCA ATGTGGCGCTGATGAAGCGCATGGTCAATGAGGGGTATCAGGACGCTGAAAGTCTGTTGCGTCGCATCCGGGATGTTGAG CTGTGGCTGGATAATCCGCTTCTGATGCGAGCGGACAAAAATGCCAGCTACGCGGCACGGCTTCGGGTCGATCTGAGCGA GATCAGGGAGCCGATCCTGGCCTGCCCCAATGATCCCGATGATGTCAGGCTGTTGTCGGAGGTGGCCGGGACACCGATCC AGGATGTGTTCATCGGCTCCTGCATGGCCAACATCGGCCATTTTCGCGCAGCCGCCGAGATCTGGCGCGGCCAGACGTTC AATCCCCAGGTCCGCATCTGGCTCTGCCCCCCCACGCGCATGGATGAACAGCAGCTGCGTGACGAGGCCTGTTTCCAGGT ATTCGGCGCAGTCGGCGCGCGCATGGAAATGCCCGGCTGTTCGCTCTGCATGGGCAACCAAGCCCGGGTGCCGGACGGGG TGACCGTGTTTTCCACCTCCACCAGGAATTTTGACGACCGCATGGGCAATGGCGCCAGAGTGTACCTGGGGTCTGCCGAA CTGGGCGCGGTTGTCGCTCTTTTGGGGCGTTTGCCCGAACCGGACGAGTATCTGAGGCTGTACCGGGAGCGGGTGGAGCC GCAGCGGGAGAGGATCTACCGCTCCCTGCGCTTCGATGAGCGGTCGGAGCAGTAA
Upstream 100 bases:
>100_bases CAGCGGCGACGTGACCGGCGACAACCGCCAGGTGGTGGGCTACGCCGCCGTGCTGGTGGCCTGAGCCGCTCCCCCCCTTG CCTTTGTCAGGAGAACAGTG
Downstream 100 bases:
>100_bases AGAGATAGCTGGGTGCGCCTTTCCCCGTTTCCGTGGGGCTCCGCTCCGTGGTGCCGCATTATCTGGTTGACGATTCTTAT TTATGTTTTATTATCTTCAT
Product: bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase
Products: NA
Alternate protein names: Aconitase 2; 2-methylisocitrate dehydratase; Citrate hydro-lyase 2 [H]
Number of amino acids: Translated: 844; Mature: 844
Protein sequence:
>844_residues MIQEYLHHEQERARQGIPPLPLSAEQTARLCALLTAPPSGREEFLLTLLERRVPPGVDPAAKVKAGFLTNIVSGALQSPL LTPFDAIRILGGMLGGYNVAPLVAALSDPELVGEAADQLSRITLVHGAFDQVAALVREGNQAASRVMRSWAEGEWFTRRA PLPATIRLKVYRVQGEINTDDFSPAGDAWSRPDIPLHALVMGRRRFPDGLATMAAFREEGCRIAFVGDVIGTGSSRKSAC NSLLWAIGEDIPGVPNKRGGGVIIGGVIAPIFFNTAQDSGALPIRAEVGALSTGDLIVVDTVRGIISDEQGANVLSRFSL APATLADEFRAGGRIPLIIGRALTDRARSFLGLPGSTLFTLPDNPVPEPGQGFTLAQKMVGAACGVGGVLPGSACQPVMT TVGSQDTTGPMTADELKELACLSFQAPLVMQSFCHTAAYPKLSDLAMHRTLPSFITQRGGVSLRPGDGVIHSWLNRLLLP DRVGTGGDSHTRFPLGISFPAGSGLVAFAAAMGFMPLDMPESVLVRFSGSLNSGITLRDAVNAIPLQAIREGLLTVPKQN KVNIFSGRILEMEGISDLSVEQAFELTDSAAERSAAAGCIQLSEERVAEFLRSNVALMKRMVNEGYQDAESLLRRIRDVE LWLDNPLLMRADKNASYAARLRVDLSEIREPILACPNDPDDVRLLSEVAGTPIQDVFIGSCMANIGHFRAAAEIWRGQTF NPQVRIWLCPPTRMDEQQLRDEACFQVFGAVGARMEMPGCSLCMGNQARVPDGVTVFSTSTRNFDDRMGNGARVYLGSAE LGAVVALLGRLPEPDEYLRLYRERVEPQRERIYRSLRFDERSEQ
Sequences:
>Translated_844_residues MIQEYLHHEQERARQGIPPLPLSAEQTARLCALLTAPPSGREEFLLTLLERRVPPGVDPAAKVKAGFLTNIVSGALQSPL LTPFDAIRILGGMLGGYNVAPLVAALSDPELVGEAADQLSRITLVHGAFDQVAALVREGNQAASRVMRSWAEGEWFTRRA PLPATIRLKVYRVQGEINTDDFSPAGDAWSRPDIPLHALVMGRRRFPDGLATMAAFREEGCRIAFVGDVIGTGSSRKSAC NSLLWAIGEDIPGVPNKRGGGVIIGGVIAPIFFNTAQDSGALPIRAEVGALSTGDLIVVDTVRGIISDEQGANVLSRFSL APATLADEFRAGGRIPLIIGRALTDRARSFLGLPGSTLFTLPDNPVPEPGQGFTLAQKMVGAACGVGGVLPGSACQPVMT TVGSQDTTGPMTADELKELACLSFQAPLVMQSFCHTAAYPKLSDLAMHRTLPSFITQRGGVSLRPGDGVIHSWLNRLLLP DRVGTGGDSHTRFPLGISFPAGSGLVAFAAAMGFMPLDMPESVLVRFSGSLNSGITLRDAVNAIPLQAIREGLLTVPKQN KVNIFSGRILEMEGISDLSVEQAFELTDSAAERSAAAGCIQLSEERVAEFLRSNVALMKRMVNEGYQDAESLLRRIRDVE LWLDNPLLMRADKNASYAARLRVDLSEIREPILACPNDPDDVRLLSEVAGTPIQDVFIGSCMANIGHFRAAAEIWRGQTF NPQVRIWLCPPTRMDEQQLRDEACFQVFGAVGARMEMPGCSLCMGNQARVPDGVTVFSTSTRNFDDRMGNGARVYLGSAE LGAVVALLGRLPEPDEYLRLYRERVEPQRERIYRSLRFDERSEQ >Mature_844_residues MIQEYLHHEQERARQGIPPLPLSAEQTARLCALLTAPPSGREEFLLTLLERRVPPGVDPAAKVKAGFLTNIVSGALQSPL LTPFDAIRILGGMLGGYNVAPLVAALSDPELVGEAADQLSRITLVHGAFDQVAALVREGNQAASRVMRSWAEGEWFTRRA PLPATIRLKVYRVQGEINTDDFSPAGDAWSRPDIPLHALVMGRRRFPDGLATMAAFREEGCRIAFVGDVIGTGSSRKSAC NSLLWAIGEDIPGVPNKRGGGVIIGGVIAPIFFNTAQDSGALPIRAEVGALSTGDLIVVDTVRGIISDEQGANVLSRFSL APATLADEFRAGGRIPLIIGRALTDRARSFLGLPGSTLFTLPDNPVPEPGQGFTLAQKMVGAACGVGGVLPGSACQPVMT TVGSQDTTGPMTADELKELACLSFQAPLVMQSFCHTAAYPKLSDLAMHRTLPSFITQRGGVSLRPGDGVIHSWLNRLLLP DRVGTGGDSHTRFPLGISFPAGSGLVAFAAAMGFMPLDMPESVLVRFSGSLNSGITLRDAVNAIPLQAIREGLLTVPKQN KVNIFSGRILEMEGISDLSVEQAFELTDSAAERSAAAGCIQLSEERVAEFLRSNVALMKRMVNEGYQDAESLLRRIRDVE LWLDNPLLMRADKNASYAARLRVDLSEIREPILACPNDPDDVRLLSEVAGTPIQDVFIGSCMANIGHFRAAAEIWRGQTF NPQVRIWLCPPTRMDEQQLRDEACFQVFGAVGARMEMPGCSLCMGNQARVPDGVTVFSTSTRNFDDRMGNGARVYLGSAE LGAVVALLGRLPEPDEYLRLYRERVEPQRERIYRSLRFDERSEQ
Specific function: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate as well as the dehydration of 2-methylisocitrate to cis-2-methylaconitate [H]
COG id: COG1049
COG function: function code C; Aconitase B
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aconitase/IPM isomerase family [H]
Homologues:
Organism=Escherichia coli, GI2367097, Length=853, Percent_Identity=59.4372801875733, Blast_Score=971, Evalue=0.0, Organism=Escherichia coli, GI1786259, Length=369, Percent_Identity=26.8292682926829, Blast_Score=79, Evalue=1e-15,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015931 - InterPro: IPR015937 - InterPro: IPR001030 - InterPro: IPR015928 - InterPro: IPR018136 - InterPro: IPR004406 - InterPro: IPR015930 - InterPro: IPR015933 - InterPro: IPR015929 [H]
Pfam domain/function: PF00330 Aconitase; PF06434 Aconitase_2_N; PF11791 Aconitase_B_N [H]
EC number: =4.2.1.3; =4.2.1.99 [H]
Molecular weight: Translated: 91186; Mature: 91186
Theoretical pI: Translated: 5.52; Mature: 5.52
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.7 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 4.4 %Cys+Met (Translated Protein) 1.7 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 4.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIQEYLHHEQERARQGIPPLPLSAEQTARLCALLTAPPSGREEFLLTLLERRVPPGVDPA CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCCCCCHH AKVKAGFLTNIVSGALQSPLLTPFDAIRILGGMLGGYNVAPLVAALSDPELVGEAADQLS HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHH RITLVHGAFDQVAALVREGNQAASRVMRSWAEGEWFTRRAPLPATIRLKVYRVQGEINTD HHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCEEECCCCCEEEEEEEEEEECCCCCC DFSPAGDAWSRPDIPLHALVMGRRRFPDGLATMAAFREEGCRIAFVGDVIGTGSSRKSAC CCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHH NSLLWAIGEDIPGVPNKRGGGVIIGGVIAPIFFNTAQDSGALPIRAEVGALSTGDLIVVD HHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCEEEEE TVRGIISDEQGANVLSRFSLAPATLADEFRAGGRIPLIIGRALTDRARSFLGLPGSTLFT CHHHHHCCCCCHHHHHHHHCCHHHHHHHHHCCCCCEEEECHHHHHHHHHHHCCCCCEEEE LPDNPVPEPGQGFTLAQKMVGAACGVGGVLPGSACQPVMTTVGSQDTTGPMTADELKELA CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHH CLSFQAPLVMQSFCHTAAYPKLSDLAMHRTLPSFITQRGGVSLRPGDGVIHSWLNRLLLP HHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHCCC DRVGTGGDSHTRFPLGISFPAGSGLVAFAAAMGFMPLDMPESVLVRFSGSLNSGITLRDA CCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHEEECCCCCCCEEHHHH VNAIPLQAIREGLLTVPKQNKVNIFSGRILEMEGISDLSVEQAFELTDSAAERSAAAGCI HHHCCHHHHHHHHHCCCCCCCEEEECCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH QLSEERVAEFLRSNVALMKRMVNEGYQDAESLLRRIRDVELWLDNPLLMRADKNASYAAR HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEECCCEEEEECCCCCEEEE LRVDLSEIREPILACPNDPDDVRLLSEVAGTPIQDVFIGSCMANIGHFRAAAEIWRGQTF EEECHHHHHHHHEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC NPQVRIWLCPPTRMDEQQLRDEACFQVFGAVGARMEMPGCSLCMGNQARVPDGVTVFSTS CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCEEEEECC TRNFDDRMGNGARVYLGSAELGAVVALLGRLPEPDEYLRLYRERVEPQRERIYRSLRFDE CCCHHHHCCCCCEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCC RSEQ CCCC >Mature Secondary Structure MIQEYLHHEQERARQGIPPLPLSAEQTARLCALLTAPPSGREEFLLTLLERRVPPGVDPA CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCCCCCHH AKVKAGFLTNIVSGALQSPLLTPFDAIRILGGMLGGYNVAPLVAALSDPELVGEAADQLS HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHH RITLVHGAFDQVAALVREGNQAASRVMRSWAEGEWFTRRAPLPATIRLKVYRVQGEINTD HHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCEEECCCCCEEEEEEEEEEECCCCCC DFSPAGDAWSRPDIPLHALVMGRRRFPDGLATMAAFREEGCRIAFVGDVIGTGSSRKSAC CCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHH NSLLWAIGEDIPGVPNKRGGGVIIGGVIAPIFFNTAQDSGALPIRAEVGALSTGDLIVVD HHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCEEEEE TVRGIISDEQGANVLSRFSLAPATLADEFRAGGRIPLIIGRALTDRARSFLGLPGSTLFT CHHHHHCCCCCHHHHHHHHCCHHHHHHHHHCCCCCEEEECHHHHHHHHHHHCCCCCEEEE LPDNPVPEPGQGFTLAQKMVGAACGVGGVLPGSACQPVMTTVGSQDTTGPMTADELKELA CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHH CLSFQAPLVMQSFCHTAAYPKLSDLAMHRTLPSFITQRGGVSLRPGDGVIHSWLNRLLLP HHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHCCC DRVGTGGDSHTRFPLGISFPAGSGLVAFAAAMGFMPLDMPESVLVRFSGSLNSGITLRDA CCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHEEECCCCCCCEEHHHH VNAIPLQAIREGLLTVPKQNKVNIFSGRILEMEGISDLSVEQAFELTDSAAERSAAAGCI HHHCCHHHHHHHHHCCCCCCCEEEECCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH QLSEERVAEFLRSNVALMKRMVNEGYQDAESLLRRIRDVELWLDNPLLMRADKNASYAAR HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEECCCEEEEECCCCCEEEE LRVDLSEIREPILACPNDPDDVRLLSEVAGTPIQDVFIGSCMANIGHFRAAAEIWRGQTF EEECHHHHHHHHEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC NPQVRIWLCPPTRMDEQQLRDEACFQVFGAVGARMEMPGCSLCMGNQARVPDGVTVFSTS CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCEEEEECC TRNFDDRMGNGARVYLGSAELGAVVALLGRLPEPDEYLRLYRERVEPQRERIYRSLRFDE CCCHHHHCCCCCEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCC RSEQ CCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8905231 [H]