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The map label for this gene is trpS [H]

Identifier: 118580108

GI number: 118580108

Start: 1814039

End: 1815019

Strand: Direct

Name: trpS [H]

Synonym: Ppro_1687

Alternate gene names: 118580108

Gene position: 1814039-1815019 (Clockwise)

Preceding gene: 118580107

Following gene: 118580109

Centisome position: 45.26

GC content: 59.12

Gene sequence:

>981_bases
ATGAAAGAGCGTGTTGTCAGCGGCATGAGGCCCACCGGGCGCCTGCACATAGGTCATTTTCATGGAGTTCTGGAAAACTG
GATCAGGATTCAGGATCAGATGGAGTGCTTCTTCTTTGTGGCGGACTGGCATTCATTGACCACGGAATACGCCGATACGG
CGGCCATCAGGGACAATATCCGCGAGATGGTGCTGGACTGGGTCGCCTTCGGACTTGACCCCGAAAAAACGGTGGTCTTC
CGCCAGAGCCTGGTCCCCCACCATGCCGAACTGAACCTGATACTCTCCATGATCACGCCGGTCTCCTGGCTGGAGCGTAA
CCCAACCTTCAAGGAGATGCTGGACAATATCCAACAGCGTGACCTCTCCACCTTCGGTTTTCTCGGTTATCCGGTGCTGA
TGGCCGCCGATATCATCCTCTACAAGGCCACCCGCGTGCCGGTTGGGCAGGACCAGTTACCCCACCTGGAGATCACCCGC
GAGATCGCTCGGCGCTTCAACCATCTTTATGGCCAGGTGTTCCCCGAACCGGCCGCCCTGCTGACCGAGACACCCAAGCT
CTTGGGGCTTGACGGCCGCAAGATGAGCAAGTCCTACAACAACTCCATCTACCTGTCGGACACGGCCGAGGAGACCGAGA
AGAAGATCAAGTCCATGATGACCGATCCGGCCCGCATGCGGCGCAGCGATGCGGGCGATCCGGAGGTGTGCGTAGCCTTT
AACCTGCACCGCATCTATGTCCCCCAGGAACAGCAGGACGAGATCGTTCCGGCCTGCCGCAACGCATCCATCGGCTGCGT
AGAGTGCAAGAAGATCCTGGCCAAATACCTGAACGAGCGCCTGGCTCCCTTCCGAGCCAAGCGGGTGGAGCTTACCCAAA
AGTCCGACTTCGTCGACAACCTCCTCCACAATGGCAGCAAACGGGCGTCCGTCATCTCCGATGCCGTCATGGCGGAGGCT
CGCGCAGCCCTGAAGCTGTGA

Upstream 100 bases:

>100_bases
TGGGAGTGACCAGCCTGATGATGCGCTGAAGCGAAAGTCGCCATTACCCATCATGCTTCCCGCTGGTCAGGGGGTATGAA
GCCATAAGGAGTCGTGATAG

Downstream 100 bases:

>100_bases
GACCGGACAATCCATGAGTTCCACCAGCGGCCAGCAGGAGGAGAACCTTCCCCTGGAGGGTTTCCAGGATGTCTACCACG
TGCGCCTGGACAAGTTCGAC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MKERVVSGMRPTGRLHIGHFHGVLENWIRIQDQMECFFFVADWHSLTTEYADTAAIRDNIREMVLDWVAFGLDPEKTVVF
RQSLVPHHAELNLILSMITPVSWLERNPTFKEMLDNIQQRDLSTFGFLGYPVLMAADIILYKATRVPVGQDQLPHLEITR
EIARRFNHLYGQVFPEPAALLTETPKLLGLDGRKMSKSYNNSIYLSDTAEETEKKIKSMMTDPARMRRSDAGDPEVCVAF
NLHRIYVPQEQQDEIVPACRNASIGCVECKKILAKYLNERLAPFRAKRVELTQKSDFVDNLLHNGSKRASVISDAVMAEA
RAALKL

Sequences:

>Translated_326_residues
MKERVVSGMRPTGRLHIGHFHGVLENWIRIQDQMECFFFVADWHSLTTEYADTAAIRDNIREMVLDWVAFGLDPEKTVVF
RQSLVPHHAELNLILSMITPVSWLERNPTFKEMLDNIQQRDLSTFGFLGYPVLMAADIILYKATRVPVGQDQLPHLEITR
EIARRFNHLYGQVFPEPAALLTETPKLLGLDGRKMSKSYNNSIYLSDTAEETEKKIKSMMTDPARMRRSDAGDPEVCVAF
NLHRIYVPQEQQDEIVPACRNASIGCVECKKILAKYLNERLAPFRAKRVELTQKSDFVDNLLHNGSKRASVISDAVMAEA
RAALKL
>Mature_326_residues
MKERVVSGMRPTGRLHIGHFHGVLENWIRIQDQMECFFFVADWHSLTTEYADTAAIRDNIREMVLDWVAFGLDPEKTVVF
RQSLVPHHAELNLILSMITPVSWLERNPTFKEMLDNIQQRDLSTFGFLGYPVLMAADIILYKATRVPVGQDQLPHLEITR
EIARRFNHLYGQVFPEPAALLTETPKLLGLDGRKMSKSYNNSIYLSDTAEETEKKIKSMMTDPARMRRSDAGDPEVCVAF
NLHRIYVPQEQQDEIVPACRNASIGCVECKKILAKYLNERLAPFRAKRVELTQKSDFVDNLLHNGSKRASVISDAVMAEA
RAALKL

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=327, Percent_Identity=33.9449541284404, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI41352700, Length=182, Percent_Identity=41.2087912087912, Blast_Score=153, Evalue=2e-37,
Organism=Escherichia coli, GI1789786, Length=228, Percent_Identity=39.0350877192982, Blast_Score=155, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI71982800, Length=331, Percent_Identity=31.7220543806647, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71982793, Length=331, Percent_Identity=31.7220543806647, Blast_Score=141, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6320474, Length=240, Percent_Identity=37.9166666666667, Blast_Score=152, Evalue=7e-38,
Organism=Drosophila melanogaster, GI24666151, Length=227, Percent_Identity=37.8854625550661, Blast_Score=148, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37229; Mature: 37229

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKERVVSGMRPTGRLHIGHFHGVLENWIRIQDQMECFFFVADWHSLTTEYADTAAIRDNI
CCCCHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHEEEEEEEHHHHHHHHHHHHHHHHHHH
REMVLDWVAFGLDPEKTVVFRQSLVPHHAELNLILSMITPVSWLERNPTFKEMLDNIQQR
HHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
DLSTFGFLGYPVLMAADIILYKATRVPVGQDQLPHLEITREIARRFNHLYGQVFPEPAAL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
LTETPKLLGLDGRKMSKSYNNSIYLSDTAEETEKKIKSMMTDPARMRRSDAGDPEVCVAF
HHCCCHHCCCCCHHHHHCCCCEEEEECCHHHHHHHHHHHHCCHHHHHHCCCCCCCEEEEE
NLHRIYVPQEQQDEIVPACRNASIGCVECKKILAKYLNERLAPFRAKRVELTQKSDFVDN
EEEEEECCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LLHNGSKRASVISDAVMAEARAALKL
HHHCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKERVVSGMRPTGRLHIGHFHGVLENWIRIQDQMECFFFVADWHSLTTEYADTAAIRDNI
CCCCHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHEEEEEEEHHHHHHHHHHHHHHHHHHH
REMVLDWVAFGLDPEKTVVFRQSLVPHHAELNLILSMITPVSWLERNPTFKEMLDNIQQR
HHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
DLSTFGFLGYPVLMAADIILYKATRVPVGQDQLPHLEITREIARRFNHLYGQVFPEPAAL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
LTETPKLLGLDGRKMSKSYNNSIYLSDTAEETEKKIKSMMTDPARMRRSDAGDPEVCVAF
HHCCCHHCCCCCHHHHHCCCCEEEEECCHHHHHHHHHHHHCCHHHHHHCCCCCCCEEEEE
NLHRIYVPQEQQDEIVPACRNASIGCVECKKILAKYLNERLAPFRAKRVELTQKSDFVDN
EEEEEECCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LLHNGSKRASVISDAVMAEARAALKL
HHHCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]