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The map label for this gene is rsbU [H]

Identifier: 118580045

GI number: 118580045

Start: 1737294

End: 1739621

Strand: Reverse

Name: rsbU [H]

Synonym: Ppro_1622

Alternate gene names: 118580045

Gene position: 1739621-1737294 (Counterclockwise)

Preceding gene: 118580065

Following gene: 118580044

Centisome position: 43.4

GC content: 60.65

Gene sequence:

>2328_bases
ATGCCCCGCCCCCTCCACCGTTGGCCCCTTCTCGAAGCCGCCCCATCCCCCCCCTCTCCTTCCCTGCATCAATCGCCAGG
ACAACGGGCAGGCGCCCTGATACTCCTTGTGGCCGTCATCATGATGATCGCCCTGCCCTGCGCCGCCTCGGCACAGGAGA
CTCAGCACAGGCAGGTGCTGGTGCTGCACTCGTACCACAAGGGCTTCAAATGGACCGACGACATCAGCCAGGGCATAGCA
TCCAGCCTGAACGAACAGGGGATCAAGACCAGGATCCACTACGAGTATATGGATACCAAGCGAGTGTCCGGTCCCCGCTA
TACCGGGTTGCTGCGCGAGACCTACCGCCTGAAATTCAGCGCCATGAAATTCCGGGTGATCATCGCATCGGACAACGACG
CCTTCGACTTTCTGCTCTCCTACCGCGACGACCTGTTTCCCGGAACGCCGGTGGTATTCTGCGGGGTCAATGACTTCGAG
CCGTCCCAATTGCACGGCACGCGGCTCTTCACCGGTGTCAACGAGTCGGCCGACCTGGCAGCCACCTTCGACCTGGCCCT
GAGACTCCACCCCTCGGTCAGGAGAATTGTCGTCATCAACGACACCACGACCACCGGTCGCATCATGCATCGCAAGATCG
TATCCCTGATCCCCTCCCTCCGCAGACGCGTGGAGCTGACCTTTCTGGAAGCCGTGACCATCCCCGAGATCAGGGAAGAA
TTGGCAAAGCTTGAGAGCGACAGCCTGGTGTTCTTTACCCTCTTCTTTCAGGACAGCAAAGGACGGTTTCTGGAGTATGA
CGAGGCCATCTCGCTGCTCGCGCCCCTTTGCCCAGTCCCCATCTACGGAGTATGGGATTTCTACCTGGGCAACGGCATCG
TGGGGGGCATGCTGACCAGCGGCTTTTCCCAGGGGAAGGCAGCCGCAAGAATCGCGGGGCGCATCCTGGAGGGTGAAGCT
CCCCAGCGCATCCCGGTGGTGATGAAGAGCCCCAACAGCTTCATGTTCGACTACCAGCAACTGTCCAGGTTCCACATTCC
CCGATCCGCCCTGCCGAAGGGCAGCATTATCATCAACAGTCCCGCCTCCCGCTACTCCGTGCCGCGCAGCGTCTTCTGGG
GTGCGGTTGCCGCCCTGGTCGGTTCGGCCCTGATCATCCTGTTTCTGACCTACAACACCATACGACGCATGAGGGCCGAG
GAACGCAGCCGGCGCCTGGCGGCAATCGTCGACTCATCCGATGACGCAATCATCGGCAAGACGCCGGACGGCGTCATTAC
CAGCTGGAACAGGGGCGCCGCGAACAAGTTCGGCTATGGAGAGGAAGAGATGCTCGGCAAGTCAGTCACCCTTCTGGTTC
CTCCCGAACAGCGGGACAACGTGCTTCGCGTCCACGAGAAGATCCGCCGCGGCGAGCATGTGGAACATTTTGAAACCGTA
CACATGAGAAAGAATGGCGAACGAATCCACATGTCCCTCACCTTCTCGCCGGTGACCGACAGCCAGGGGCGGGTCATCGC
CGTCTCCACCATCGGGCGCGACATCTCCGAGCGTAAGAGAGCCGAACAGCTGCTGCTGGAAAACGCTCTGATCAATAGGG
AACTGGAAATTGCCCAGCAGATCCAGCAGTCCTTTCTGCAGGAGTGTCCCCAGGAACTACCCGGACTGCTCATGGCATGC
CGCTGCGAACCAGCCGCCAAGGTGGGGGGTGACTACTACGACCTGTTCACCCCCCGGGAGGGGCTGGTGGATTGCGTCAT
CGCCGACATCACCGGCCACAGCGTCGGTTCGGCCCTGCTGATGACAGAAACCCGCAGCGTCCTCCAGGCCGAGGTAACCC
CCGGACGCACACCGGGACAACTGCTGGCCGAGGTGAACAACCTGCTGTACAACGACCTGTCACGTGCGGAGATGCAGTTG
AGTATGTTCTATGCGCGCATCGACACGCCCAACCAGAGGCTCTCCTACGCCAACGCGGGACACTGCCGTCCGCTCCTGTA
CCATTCCCGTGGCAAATCGGTGCAGGAACTTGATGCCGACGGCCTGATCCTGGGAATCAGGCGGGGTGTCTGCTTTGAAG
AAGCCAGCATCGAGGTGGAAGCAGGGGATGTGCTGCTACTGTACACGGACGGTGTCATTGAAGCGGAACGAGATCGGGGA
GAGTTCTTCGGCAGCGACCGACTGAGCCGACTGCTCACGGAGCAGCATGAACGGCATCCGCGGGAGATTATCGATAAAAT
CCTGGCCGAGGTGACCCGTTTTACCAGGACCAGGGTACGAGCCGATGACATCGCCCTGTTCGTGGTCACATTCACCCCGG
ATGCCTGA

Upstream 100 bases:

>100_bases
ACGCTGCTTCCAGCCACCATCCGCTCCCCGCGAGCCGCCGCGAGTACATTGCGTACGTTCTCGTACCTGTCGCGATTCCA
CATTCACAGGAGAGGATCAC

Downstream 100 bases:

>100_bases
CCAGTGTATCGGCCGTTCCTCTCGTAGCAGAGACGTTCGCGGCGTGCCCGTTCAACGTCTGCAGCGCTCCCCTCCCCTTT
TCTGGGCGTTCTATTCGGGG

Product: putative PAS/PAC sensor protein

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 775; Mature: 774

Protein sequence:

>775_residues
MPRPLHRWPLLEAAPSPPSPSLHQSPGQRAGALILLVAVIMMIALPCAASAQETQHRQVLVLHSYHKGFKWTDDISQGIA
SSLNEQGIKTRIHYEYMDTKRVSGPRYTGLLRETYRLKFSAMKFRVIIASDNDAFDFLLSYRDDLFPGTPVVFCGVNDFE
PSQLHGTRLFTGVNESADLAATFDLALRLHPSVRRIVVINDTTTTGRIMHRKIVSLIPSLRRRVELTFLEAVTIPEIREE
LAKLESDSLVFFTLFFQDSKGRFLEYDEAISLLAPLCPVPIYGVWDFYLGNGIVGGMLTSGFSQGKAAARIAGRILEGEA
PQRIPVVMKSPNSFMFDYQQLSRFHIPRSALPKGSIIINSPASRYSVPRSVFWGAVAALVGSALIILFLTYNTIRRMRAE
ERSRRLAAIVDSSDDAIIGKTPDGVITSWNRGAANKFGYGEEEMLGKSVTLLVPPEQRDNVLRVHEKIRRGEHVEHFETV
HMRKNGERIHMSLTFSPVTDSQGRVIAVSTIGRDISERKRAEQLLLENALINRELEIAQQIQQSFLQECPQELPGLLMAC
RCEPAAKVGGDYYDLFTPREGLVDCVIADITGHSVGSALLMTETRSVLQAEVTPGRTPGQLLAEVNNLLYNDLSRAEMQL
SMFYARIDTPNQRLSYANAGHCRPLLYHSRGKSVQELDADGLILGIRRGVCFEEASIEVEAGDVLLLYTDGVIEAERDRG
EFFGSDRLSRLLTEQHERHPREIIDKILAEVTRFTRTRVRADDIALFVVTFTPDA

Sequences:

>Translated_775_residues
MPRPLHRWPLLEAAPSPPSPSLHQSPGQRAGALILLVAVIMMIALPCAASAQETQHRQVLVLHSYHKGFKWTDDISQGIA
SSLNEQGIKTRIHYEYMDTKRVSGPRYTGLLRETYRLKFSAMKFRVIIASDNDAFDFLLSYRDDLFPGTPVVFCGVNDFE
PSQLHGTRLFTGVNESADLAATFDLALRLHPSVRRIVVINDTTTTGRIMHRKIVSLIPSLRRRVELTFLEAVTIPEIREE
LAKLESDSLVFFTLFFQDSKGRFLEYDEAISLLAPLCPVPIYGVWDFYLGNGIVGGMLTSGFSQGKAAARIAGRILEGEA
PQRIPVVMKSPNSFMFDYQQLSRFHIPRSALPKGSIIINSPASRYSVPRSVFWGAVAALVGSALIILFLTYNTIRRMRAE
ERSRRLAAIVDSSDDAIIGKTPDGVITSWNRGAANKFGYGEEEMLGKSVTLLVPPEQRDNVLRVHEKIRRGEHVEHFETV
HMRKNGERIHMSLTFSPVTDSQGRVIAVSTIGRDISERKRAEQLLLENALINRELEIAQQIQQSFLQECPQELPGLLMAC
RCEPAAKVGGDYYDLFTPREGLVDCVIADITGHSVGSALLMTETRSVLQAEVTPGRTPGQLLAEVNNLLYNDLSRAEMQL
SMFYARIDTPNQRLSYANAGHCRPLLYHSRGKSVQELDADGLILGIRRGVCFEEASIEVEAGDVLLLYTDGVIEAERDRG
EFFGSDRLSRLLTEQHERHPREIIDKILAEVTRFTRTRVRADDIALFVVTFTPDA
>Mature_774_residues
PRPLHRWPLLEAAPSPPSPSLHQSPGQRAGALILLVAVIMMIALPCAASAQETQHRQVLVLHSYHKGFKWTDDISQGIAS
SLNEQGIKTRIHYEYMDTKRVSGPRYTGLLRETYRLKFSAMKFRVIIASDNDAFDFLLSYRDDLFPGTPVVFCGVNDFEP
SQLHGTRLFTGVNESADLAATFDLALRLHPSVRRIVVINDTTTTGRIMHRKIVSLIPSLRRRVELTFLEAVTIPEIREEL
AKLESDSLVFFTLFFQDSKGRFLEYDEAISLLAPLCPVPIYGVWDFYLGNGIVGGMLTSGFSQGKAAARIAGRILEGEAP
QRIPVVMKSPNSFMFDYQQLSRFHIPRSALPKGSIIINSPASRYSVPRSVFWGAVAALVGSALIILFLTYNTIRRMRAEE
RSRRLAAIVDSSDDAIIGKTPDGVITSWNRGAANKFGYGEEEMLGKSVTLLVPPEQRDNVLRVHEKIRRGEHVEHFETVH
MRKNGERIHMSLTFSPVTDSQGRVIAVSTIGRDISERKRAEQLLLENALINRELEIAQQIQQSFLQECPQELPGLLMACR
CEPAAKVGGDYYDLFTPREGLVDCVIADITGHSVGSALLMTETRSVLQAEVTPGRTPGQLLAEVNNLLYNDLSRAEMQLS
MFYARIDTPNQRLSYANAGHCRPLLYHSRGKSVQELDADGLILGIRRGVCFEEASIEVEAGDVLLLYTDGVIEAERDRGE
FFGSDRLSRLLTEQHERHPREIIDKILAEVTRFTRTRVRADDIALFVVTFTPDA

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 86748; Mature: 86617

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50112 PAS ; PS50113 PAC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPLHRWPLLEAAPSPPSPSLHQSPGQRAGALILLVAVIMMIALPCAASAQETQHRQVL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
VLHSYHKGFKWTDDISQGIASSLNEQGIKTRIHYEYMDTKRVSGPRYTGLLRETYRLKFS
EEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHEEE
AMKFRVIIASDNDAFDFLLSYRDDLFPGTPVVFCGVNDFEPSQLHGTRLFTGVNESADLA
EEEEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCE
ATFDLALRLHPSVRRIVVINDTTTTGRIMHRKIVSLIPSLRRRVELTFLEAVTIPEIREE
EEEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHEEHHHHHCCCHHHHHH
LAKLESDSLVFFTLFFQDSKGRFLEYDEAISLLAPLCPVPIYGVWDFYLGNGIVGGMLTS
HHHCCCCCEEEEEEEEECCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHC
GFSQGKAAARIAGRILEGEAPQRIPVVMKSPNSFMFDYQQLSRFHIPRSALPKGSIIINS
CCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEHHHHHHHCCCHHCCCCCCEEECC
PASRYSVPRSVFWGAVAALVGSALIILFLTYNTIRRMRAEERSRRLAAIVDSSDDAIIGK
CHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCEEEEC
TPDGVITSWNRGAANKFGYGEEEMLGKSVTLLVPPEQRDNVLRVHEKIRRGEHVEHFETV
CCCCCEECCCCCCCCCCCCCHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHH
HMRKNGERIHMSLTFSPVTDSQGRVIAVSTIGRDISERKRAEQLLLENALINRELEIAQQ
HEECCCCEEEEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
IQQSFLQECPQELPGLLMACRCEPAAKVGGDYYDLFTPREGLVDCVIADITGHSVGSALL
HHHHHHHHHHHHHHHHHEECCCCCHHHCCCCEEECCCCCCHHHEEEEEECCCCCCCCCHH
MTETRSVLQAEVTPGRTPGQLLAEVNNLLYNDLSRAEMQLSMFYARIDTPNQRLSYANAG
HHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHCCCCCCC
HCRPLLYHSRGKSVQELDADGLILGIRRGVCFEEASIEVEAGDVLLLYTDGVIEAERDRG
CCCEEEEECCCCCHHHCCCCCEEEEECCCCEEECCCEEEECCCEEEEEECCCEEECCCCC
EFFGSDRLSRLLTEQHERHPREIIDKILAEVTRFTRTRVRADDIALFVVTFTPDA
HHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCC
>Mature Secondary Structure 
PRPLHRWPLLEAAPSPPSPSLHQSPGQRAGALILLVAVIMMIALPCAASAQETQHRQVL
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
VLHSYHKGFKWTDDISQGIASSLNEQGIKTRIHYEYMDTKRVSGPRYTGLLRETYRLKFS
EEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHEEE
AMKFRVIIASDNDAFDFLLSYRDDLFPGTPVVFCGVNDFEPSQLHGTRLFTGVNESADLA
EEEEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCE
ATFDLALRLHPSVRRIVVINDTTTTGRIMHRKIVSLIPSLRRRVELTFLEAVTIPEIREE
EEEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHEEHHHHHCCCHHHHHH
LAKLESDSLVFFTLFFQDSKGRFLEYDEAISLLAPLCPVPIYGVWDFYLGNGIVGGMLTS
HHHCCCCCEEEEEEEEECCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHC
GFSQGKAAARIAGRILEGEAPQRIPVVMKSPNSFMFDYQQLSRFHIPRSALPKGSIIINS
CCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEHHHHHHHCCCHHCCCCCCEEECC
PASRYSVPRSVFWGAVAALVGSALIILFLTYNTIRRMRAEERSRRLAAIVDSSDDAIIGK
CHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCEEEEC
TPDGVITSWNRGAANKFGYGEEEMLGKSVTLLVPPEQRDNVLRVHEKIRRGEHVEHFETV
CCCCCEECCCCCCCCCCCCCHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHH
HMRKNGERIHMSLTFSPVTDSQGRVIAVSTIGRDISERKRAEQLLLENALINRELEIAQQ
HEECCCCEEEEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
IQQSFLQECPQELPGLLMACRCEPAAKVGGDYYDLFTPREGLVDCVIADITGHSVGSALL
HHHHHHHHHHHHHHHHHEECCCCCHHHCCCCEEECCCCCCHHHEEEEEECCCCCCCCCHH
MTETRSVLQAEVTPGRTPGQLLAEVNNLLYNDLSRAEMQLSMFYARIDTPNQRLSYANAG
HHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHCCCCCCC
HCRPLLYHSRGKSVQELDADGLILGIRRGVCFEEASIEVEAGDVLLLYTDGVIEAERDRG
CCCEEEEECCCCCHHHCCCCCEEEEECCCCEEECCCEEEECCCEEEEEECCCEEECCCCC
EFFGSDRLSRLLTEQHERHPREIIDKILAEVTRFTRTRVRADDIALFVVTFTPDA
HHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]