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The map label for this gene is hmeD [H]

Identifier: 118579957

GI number: 118579957

Start: 1637307

End: 1638647

Strand: Reverse

Name: hmeD [H]

Synonym: Ppro_1534

Alternate gene names: 118579957

Gene position: 1638647-1637307 (Counterclockwise)

Preceding gene: 118579958

Following gene: 118579956

Centisome position: 40.88

GC content: 64.28

Gene sequence:

>1341_bases
ATGAAGATTCCAATGCTTCTGGCCACAGCGGATGAGATGCGGAAGATCGGCATCACGCCGGTCCCCGAGGGAAAACGGGT
AAGCGCCGCTCTGCAGCTGCTGGACCAGTACCGCTCCTTCGCCCGCCAGCTGTCGGTCATGCTGGAGAGCTGCACCGGCT
GCGGCGCCTGCGCCCAGGCCTGCCACAGCTATCGGGGAACGGACGACCACCATAACATCCCGGCAGCCAGGGCCGGCCTG
ATGCGCCGGGTGTACAAACGGCACTTCACTTGGCTTGGAAAGGCGCTGGGCATAGTGGGCGGCGCTCCGCAGCTGGATGC
GCAGACCCTGGAGAGCTGGATCGACTACTTCTACCAGTGCACGGTCTGCCGCCGCTGCGCCACATTCTGCCCCCTGGGGA
TCGATACCGGCGAGATCGTACTGGCGGGACGCAACATCCTCTCCCAGTTGGGAATCGCCCCCAGCTTCATGGTCACCATC
GCCCGCAACGAACTGGGTGCCGGCAACAACACCGGCATCCCCCAGCCGGCCGTGCTGGACAGCTGCGCGTTTCTGGAGCA
GGAGTTGCGGGACGAGACCGGCCTGGATATCCCCATCCCGGTGGATAAGCCGGACTCGGATCTGCTCTATCTCCCCTCCT
CATCGGAACTGTTCAGCAACGTGGAGACCCTCATGGGTGCGGCCAAGCTGTTCCACGCCCTGGGGGTCAACTGGACTATC
TCCACCACCATGCTGGAGGCGGCCAATTACGGCTTCCTCTTCAATCTGGAGCTCATGAAGGAGTTCAACCAGCGCATGCG
CGACACCGCCGCCCGGGTCGGCGCCACCACGGTCGTGGTGGGAGAATGCGGACACGGCTGGCGGGTGGCACGCATGTGCT
CCGAGGGCGCCAATGGGCCGCTCCCCTTCAACCTGGTGAACGTGCTGGACTTCATGGCCGAGCGACTGTCAGATCTAGCG
CTGCGCAAACTTCCCCTGCGGGCCACCTTGCACGACTCGTGCAACCATGCCCGGGGCACGGGGCTGGTGGATGCACCGCG
CAGAATCATGTCGGCCTGCGTGGAGGAGTTCGTGGAGATGAGCCCAAACCGGGAGAAGAACTTCTGCTGCGGCGGCGGAT
CGGGGCTCCTGATGGAGGAGATGCTGGAGATCCGCATGAAGCTGGGCAAGATGAAGGGGGAGCAGATCAGGCGCCTGCTC
CCCCTGGATTACGTGGCGGTTGCCTGCGCCAGTTGCAAGGCCCAGTTGCCCCTGGTGCTCGGGCACTACGGCATGGAGGA
GGTCAGGAGCGGCGGGGTGATCGACCTCATGGGAAAGGCGCTGCAGTTGAACCGGTTGTGA

Upstream 100 bases:

>100_bases
CCATGCTGATGGAGGCGGCCCCCACCTTCCCCACGCCGAAGGACAAACACCCCCGCTCCCCCTTTGCCGAAAAACGCGCA
CCCGGGGAGGAGTCCCGGCA

Downstream 100 bases:

>100_bases
AAGACGACGAAAGAGAGGAAATGATGATTGATGACACCACCTTCACGCTAATGGAACTGAGCCAGAAAGGGTATTTCTGC
AGCCAGATCCTGCTGATCCT

Product: hypothetical protein

Products: NA

Alternate protein names: Hme subunit D [H]

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MKIPMLLATADEMRKIGITPVPEGKRVSAALQLLDQYRSFARQLSVMLESCTGCGACAQACHSYRGTDDHHNIPAARAGL
MRRVYKRHFTWLGKALGIVGGAPQLDAQTLESWIDYFYQCTVCRRCATFCPLGIDTGEIVLAGRNILSQLGIAPSFMVTI
ARNELGAGNNTGIPQPAVLDSCAFLEQELRDETGLDIPIPVDKPDSDLLYLPSSSELFSNVETLMGAAKLFHALGVNWTI
STTMLEAANYGFLFNLELMKEFNQRMRDTAARVGATTVVVGECGHGWRVARMCSEGANGPLPFNLVNVLDFMAERLSDLA
LRKLPLRATLHDSCNHARGTGLVDAPRRIMSACVEEFVEMSPNREKNFCCGGGSGLLMEEMLEIRMKLGKMKGEQIRRLL
PLDYVAVACASCKAQLPLVLGHYGMEEVRSGGVIDLMGKALQLNRL

Sequences:

>Translated_446_residues
MKIPMLLATADEMRKIGITPVPEGKRVSAALQLLDQYRSFARQLSVMLESCTGCGACAQACHSYRGTDDHHNIPAARAGL
MRRVYKRHFTWLGKALGIVGGAPQLDAQTLESWIDYFYQCTVCRRCATFCPLGIDTGEIVLAGRNILSQLGIAPSFMVTI
ARNELGAGNNTGIPQPAVLDSCAFLEQELRDETGLDIPIPVDKPDSDLLYLPSSSELFSNVETLMGAAKLFHALGVNWTI
STTMLEAANYGFLFNLELMKEFNQRMRDTAARVGATTVVVGECGHGWRVARMCSEGANGPLPFNLVNVLDFMAERLSDLA
LRKLPLRATLHDSCNHARGTGLVDAPRRIMSACVEEFVEMSPNREKNFCCGGGSGLLMEEMLEIRMKLGKMKGEQIRRLL
PLDYVAVACASCKAQLPLVLGHYGMEEVRSGGVIDLMGKALQLNRL
>Mature_446_residues
MKIPMLLATADEMRKIGITPVPEGKRVSAALQLLDQYRSFARQLSVMLESCTGCGACAQACHSYRGTDDHHNIPAARAGL
MRRVYKRHFTWLGKALGIVGGAPQLDAQTLESWIDYFYQCTVCRRCATFCPLGIDTGEIVLAGRNILSQLGIAPSFMVTI
ARNELGAGNNTGIPQPAVLDSCAFLEQELRDETGLDIPIPVDKPDSDLLYLPSSSELFSNVETLMGAAKLFHALGVNWTI
STTMLEAANYGFLFNLELMKEFNQRMRDTAARVGATTVVVGECGHGWRVARMCSEGANGPLPFNLVNVLDFMAERLSDLA
LRKLPLRATLHDSCNHARGTGLVDAPRRIMSACVEEFVEMSPNREKNFCCGGGSGLLMEEMLEIRMKLGKMKGEQIRRLL
PLDYVAVACASCKAQLPLVLGHYGMEEVRSGGVIDLMGKALQLNRL

Specific function: Has menaquinol-oxidizing activity. The hmeC and hmeD subunits may together mediate electron transfer from menaquinol to an unidentified electron acceptor on the cytoplasmic side of the membrane [H]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR009051 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 48836; Mature: 48836

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00551 MOLYBDOPTERIN_PROK_1 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIPMLLATADEMRKIGITPVPEGKRVSAALQLLDQYRSFARQLSVMLESCTGCGACAQA
CCCCEEEECHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
CHSYRGTDDHHNIPAARAGLMRRVYKRHFTWLGKALGIVGGAPQLDAQTLESWIDYFYQC
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
TVCRRCATFCPLGIDTGEIVLAGRNILSQLGIAPSFMVTIARNELGAGNNTGIPQPAVLD
HHHHHHHHHCCCCCCCCCEEEECHHHHHHHCCCHHHHEEEEHHHCCCCCCCCCCCHHHHH
SCAFLEQELRDETGLDIPIPVDKPDSDLLYLPSSSELFSNVETLMGAAKLFHALGVNWTI
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEE
STTMLEAANYGFLFNLELMKEFNQRMRDTAARVGATTVVVGECGHGWRVARMCSEGANGP
HHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCCCCC
LPFNLVNVLDFMAERLSDLALRKLPLRATLHDSCNHARGTGLVDAPRRIMSACVEEFVEM
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHC
SPNREKNFCCGGGSGLLMEEMLEIRMKLGKMKGEQIRRLLPLDYVAVACASCKAQLPLVL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHCCCCHHH
GHYGMEEVRSGGVIDLMGKALQLNRL
HHCCHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIPMLLATADEMRKIGITPVPEGKRVSAALQLLDQYRSFARQLSVMLESCTGCGACAQA
CCCCEEEECHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
CHSYRGTDDHHNIPAARAGLMRRVYKRHFTWLGKALGIVGGAPQLDAQTLESWIDYFYQC
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
TVCRRCATFCPLGIDTGEIVLAGRNILSQLGIAPSFMVTIARNELGAGNNTGIPQPAVLD
HHHHHHHHHCCCCCCCCCEEEECHHHHHHHCCCHHHHEEEEHHHCCCCCCCCCCCHHHHH
SCAFLEQELRDETGLDIPIPVDKPDSDLLYLPSSSELFSNVETLMGAAKLFHALGVNWTI
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEE
STTMLEAANYGFLFNLELMKEFNQRMRDTAARVGATTVVVGECGHGWRVARMCSEGANGP
HHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCCCCC
LPFNLVNVLDFMAERLSDLALRKLPLRATLHDSCNHARGTGLVDAPRRIMSACVEEFVEM
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHC
SPNREKNFCCGGGSGLLMEEMLEIRMKLGKMKGEQIRRLLPLDYVAVACASCKAQLPLVL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHCCCCHHH
GHYGMEEVRSGGVIDLMGKALQLNRL
HHCCHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA