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The map label for this gene is xdhB [H]

Identifier: 118579868

GI number: 118579868

Start: 1544607

End: 1545449

Strand: Reverse

Name: xdhB [H]

Synonym: Ppro_1444

Alternate gene names: 118579868

Gene position: 1545449-1544607 (Counterclockwise)

Preceding gene: 118579869

Following gene: 118579865

Centisome position: 38.56

GC content: 66.43

Gene sequence:

>843_bases
ATGGTAGGAGCATTCAGACCACAGACCCTGCAGCAGGCGCTGGACATTCGGGGCAGCCGCATGACGACCCTCTTTGCCGG
CGGCAGCGACCTGATGGTCAGGCACCGCAGCTGGAGCGGCATCCCCCCTGCCCTGCCCGCTCCGGCGCTGATGATCGGCC
ATATTGAGGAGTTGCGGAACATCAGTGCCGATGGTGACACGCTCCGCATCGGCGCCTGCGCCACCCTGGGGGAGATACTC
GGCCATCCCGCCGTCCCGGACTACGTCAGGCTCCCCTTAAGCCGCATGGCCTCCCCATCCATCCGCGCCATCGCCACCCT
GGGGGGCAATATCGCCAACGCCTCGCCGGCCGGCGACAGCCTGCCCATGCTCTACGCCCTGGACGCCCGCCTGGAGCTGC
GATCATGCTCCCACACGGAAGAGGTGGATGTGGCAGACTTCATCGGCGGGCCGGGCAGGACGATACTTGAGGACGACCAG
ATCCTCACCCGCATCCATATCCCCCTGGCACAGTTCACCCACCTGCTGTTCGAAAAGGTGGCCGGCCGCCGCGCCAACAG
CATTGCCAAGCTCTCCCTGTATGTCGTGGCCAGGATAAGCGGCCCCAGGGTTGAGGAGGTACGGGTTGCCTTCGGTGCGG
TGGCTCCCACCGTGGTCAGGAACCGGGAGGCCGAGGCCCTGTTGGCCAGGACAGAGGCGGCACACCTACCCGGGCGAGTG
GAACAGGTGAAGGCCTGCTACGCCCCCCTGATCACCCCTATCGACGACCAGCGCTCCACCCGGGAGTACCGCAGAGACGT
GGCCCTGGGGCTTTTGGAGCGGTTTCTGCTGGGGCTCCGTTAG

Upstream 100 bases:

>100_bases
AACAGGTGCGGGAGGGGTTGACGGGGAATCTCTGCCGCTGCACCGGGTATAACATGATCGTGGATGGAATCATGCTGGCG
GCACAAGAGGGGGACGGATT

Downstream 100 bases:

>100_bases
TCGTCACCCCCCCTCTTTCAAATTGGAGAGCACTTCTCGGCCCCCGCCCCACCCCTCCCCTGCAACCGGGAGAGCGGCAC
CAACAGAATCATAGCCAGCA

Product: molybdopterin dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MVGAFRPQTLQQALDIRGSRMTTLFAGGSDLMVRHRSWSGIPPALPAPALMIGHIEELRNISADGDTLRIGACATLGEIL
GHPAVPDYVRLPLSRMASPSIRAIATLGGNIANASPAGDSLPMLYALDARLELRSCSHTEEVDVADFIGGPGRTILEDDQ
ILTRIHIPLAQFTHLLFEKVAGRRANSIAKLSLYVVARISGPRVEEVRVAFGAVAPTVVRNREAEALLARTEAAHLPGRV
EQVKACYAPLITPIDDQRSTREYRRDVALGLLERFLLGLR

Sequences:

>Translated_280_residues
MVGAFRPQTLQQALDIRGSRMTTLFAGGSDLMVRHRSWSGIPPALPAPALMIGHIEELRNISADGDTLRIGACATLGEIL
GHPAVPDYVRLPLSRMASPSIRAIATLGGNIANASPAGDSLPMLYALDARLELRSCSHTEEVDVADFIGGPGRTILEDDQ
ILTRIHIPLAQFTHLLFEKVAGRRANSIAKLSLYVVARISGPRVEEVRVAFGAVAPTVVRNREAEALLARTEAAHLPGRV
EQVKACYAPLITPIDDQRSTREYRRDVALGLLERFLLGLR
>Mature_280_residues
MVGAFRPQTLQQALDIRGSRMTTLFAGGSDLMVRHRSWSGIPPALPAPALMIGHIEELRNISADGDTLRIGACATLGEIL
GHPAVPDYVRLPLSRMASPSIRAIATLGGNIANASPAGDSLPMLYALDARLELRSCSHTEEVDVADFIGGPGRTILEDDQ
ILTRIHIPLAQFTHLLFEKVAGRRANSIAKLSLYVVARISGPRVEEVRVAFGAVAPTVVRNREAEALLARTEAAHLPGRV
EQVKACYAPLITPIDDQRSTREYRRDVALGLLERFLLGLR

Specific function: Presumed to be a dehydrogenase, but possibly an oxidase. Participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism) [H]

COG id: COG4630

COG function: function code F; Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789231, Length=271, Percent_Identity=28.7822878228782, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005107
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR002346 [H]

Pfam domain/function: PF03450 CO_deh_flav_C; PF00941 FAD_binding_5 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 30361; Mature: 30361

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGAFRPQTLQQALDIRGSRMTTLFAGGSDLMVRHRSWSGIPPALPAPALMIGHIEELRN
CCCCCCHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHC
ISADGDTLRIGACATLGEILGHPAVPDYVRLPLSRMASPSIRAIATLGGNIANASPAGDS
CCCCCCEEEEHHHHHHHHHHCCCCCCHHHHCCHHHHCCCCHHHHHHHCCCCCCCCCCCCC
LPMLYALDARLELRSCSHTEEVDVADFIGGPGRTILEDDQILTRIHIPLAQFTHLLFEKV
CCEEEEECCHHHHHCCCCCCCCCHHHHCCCCCCCEECCCHHHHHHHCCHHHHHHHHHHHH
AGRRANSIAKLSLYVVARISGPRVEEVRVAFGAVAPTVVRNREAEALLARTEAAHLPGRV
HCCCCCHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHH
EQVKACYAPLITPIDDQRSTREYRRDVALGLLERFLLGLR
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVGAFRPQTLQQALDIRGSRMTTLFAGGSDLMVRHRSWSGIPPALPAPALMIGHIEELRN
CCCCCCHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHC
ISADGDTLRIGACATLGEILGHPAVPDYVRLPLSRMASPSIRAIATLGGNIANASPAGDS
CCCCCCEEEEHHHHHHHHHHCCCCCCHHHHCCHHHHCCCCHHHHHHHCCCCCCCCCCCCC
LPMLYALDARLELRSCSHTEEVDVADFIGGPGRTILEDDQILTRIHIPLAQFTHLLFEKV
CCEEEEECCHHHHHCCCCCCCCCHHHHCCCCCCCEECCCHHHHHHHCCHHHHHHHHHHHH
AGRRANSIAKLSLYVVARISGPRVEEVRVAFGAVAPTVVRNREAEALLARTEAAHLPGRV
HCCCCCHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHH
EQVKACYAPLITPIDDQRSTREYRRDVALGLLERFLLGLR
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]