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The map label for this gene is cusC [C]

Identifier: 118579864

GI number: 118579864

Start: 1540252

End: 1541763

Strand: Reverse

Name: cusC [C]

Synonym: Ppro_1440

Alternate gene names: 118579864

Gene position: 1541763-1540252 (Counterclockwise)

Preceding gene: 118579865

Following gene: 118579863

Centisome position: 38.47

GC content: 62.63

Gene sequence:

>1512_bases
ATGAAGGCGAAAATGACACCGGCCCGGATACTGCGGCCGCTGTTCCTCTGCACCCTTGTCTGCTGGCTGTTTGGCGCTGC
CACGGCCTGGGCGCAGGAGGCCAGCGGAGACGCGCAAACTCCAGCCCCCACGACAGCCACACCGGGCACCGGCGCCCTGA
CTCTGGGGCAGTGCATCGATCTGGCCCTGGAAAAGAATCACTCCAGGCTGGCCTCCCGCTACGGCATCGAGATCGCCGAG
GCCCAGCACCGCCAGGCCCTGTCGGGCTACTGGCCCCAGATCAACGCCAAAGCCAACTACAGCATCATGGACGAGGATCC
CAACTTCATCTTTCCCGCAAAAACGTTCCAGATGCCGGCATCCACCATGACCGCAACAACGCCATTGGGACCGATGCCGA
TCTCCATACCGGCAAGCAGCTACAAGATACCCGAACAGAAGGTCAAGCTGATGGACAGGGAGAACTTCGTTGTCAGTCTG
AACGCCACCCTGCCGCTGTACACCGGCGGCCAGGTCAGCGCCGTTGTCCGCCAGGCCGAGCAGGGGATGAAGGCTGCCAG
GGAAGAGGCGCGCCGCAGCGACCTGCAGGTGGTCTACGACACCACCCGCTACTACTACGGCGCCGTGCTTGCCAGGGAGC
TACTCCAGATCGGCAGGGACGCCCTCACCCGCATGGAAGTGACCCTGGAGCTGACCGAGAGCCTCTACACCAAGGGATCC
GGAAAGGTCAAGAAGACCGACTATCTACGCAACAAGACCGTGGTGGAGTGGCTGCGCAGCACGATCGCGATCCTGGAGGC
CAACGAGCAGCTGGCCCGGGCAGCGCTGACCAACTCCATGGGAATGGAGTGGCAAAACCCGGTGGAACCGGCCCCCCAGG
AGCTCCCCTACCTACCGACCAGGGTCGAACTAAAGGAACTGGTCAGCAACGCCTACAGCTTCAACCCGGACTGGGCACGC
CTGGAGGCGGGCCTTGAGGCTGCCGCCGCCAAGATCGATGAGACCAAGAGCGGCCACCTACCCAAGATCGGGCTGTTCGG
CAACCTGAACCGCATCGAAAATTCCTACAGCAAGGGAATGGTGACTCCCGACAACAGGACCTCATGGGCCATCGGCATCG
GGCTGGAGCTCCCCTTGTTCAACGGCATGCGCACCACCGGCCAGGTGCGCGAGGCCCGGGCGCGCCTGGAAAAGATGAAA
CAGCAGCAGTTCCTGCTCAAGGAGGGGATCGCCCTGCAGGTGAAGCACATCTTCATCCAGCTGATGAGCAGCCAGCAGCA
GAAGGCGGCTTCCCAGGCAGCAGCCGCATCGTCCGAGGAAAACCGGGCACTGAACGAGCGCGCCTACCAGGAGGAGCTGG
TGGAGACCAAGGATGTGATCGAGGCCCAGCTGGTGGAGTCGCTGATGAAGGCCCAGTATTGCAAGGCGCTCTACGACCAC
ATCGAGGCCCGGGCAAACCTGGACTATGTGGTGGGAAAACAGGTGACGGACATCATCGGCGGCCAGAGATGA

Upstream 100 bases:

>100_bases
CAGTCGACATTTCTTCCAGCAACACGCACCTCCACAACCTGTTTGCCATCGAGATGACGGATCCCGCCAGCCAGGCTCTG
TCCCGCGAGAAGGAGTCCCC

Downstream 100 bases:

>100_bases
GCCGGGCAGGAACCGCGACCGCGTCCGGACATCCCTCCCCGGAACACCCCGACCCGGCATGTTCGGCCATGGCAACAAAG
GTGACGAAATGCGTCAGCTG

Product: outer membrane efflux protein

Products: NA

Alternate protein names: Outer Membrane Protein; Type I Secretion Outer Membrane Protein; Outer Membrane Macrolide Efflux Protein; Outer Membrane Protein-Like

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MKAKMTPARILRPLFLCTLVCWLFGAATAWAQEASGDAQTPAPTTATPGTGALTLGQCIDLALEKNHSRLASRYGIEIAE
AQHRQALSGYWPQINAKANYSIMDEDPNFIFPAKTFQMPASTMTATTPLGPMPISIPASSYKIPEQKVKLMDRENFVVSL
NATLPLYTGGQVSAVVRQAEQGMKAAREEARRSDLQVVYDTTRYYYGAVLARELLQIGRDALTRMEVTLELTESLYTKGS
GKVKKTDYLRNKTVVEWLRSTIAILEANEQLARAALTNSMGMEWQNPVEPAPQELPYLPTRVELKELVSNAYSFNPDWAR
LEAGLEAAAAKIDETKSGHLPKIGLFGNLNRIENSYSKGMVTPDNRTSWAIGIGLELPLFNGMRTTGQVREARARLEKMK
QQQFLLKEGIALQVKHIFIQLMSSQQQKAASQAAAASSEENRALNERAYQEELVETKDVIEAQLVESLMKAQYCKALYDH
IEARANLDYVVGKQVTDIIGGQR

Sequences:

>Translated_503_residues
MKAKMTPARILRPLFLCTLVCWLFGAATAWAQEASGDAQTPAPTTATPGTGALTLGQCIDLALEKNHSRLASRYGIEIAE
AQHRQALSGYWPQINAKANYSIMDEDPNFIFPAKTFQMPASTMTATTPLGPMPISIPASSYKIPEQKVKLMDRENFVVSL
NATLPLYTGGQVSAVVRQAEQGMKAAREEARRSDLQVVYDTTRYYYGAVLARELLQIGRDALTRMEVTLELTESLYTKGS
GKVKKTDYLRNKTVVEWLRSTIAILEANEQLARAALTNSMGMEWQNPVEPAPQELPYLPTRVELKELVSNAYSFNPDWAR
LEAGLEAAAAKIDETKSGHLPKIGLFGNLNRIENSYSKGMVTPDNRTSWAIGIGLELPLFNGMRTTGQVREARARLEKMK
QQQFLLKEGIALQVKHIFIQLMSSQQQKAASQAAAASSEENRALNERAYQEELVETKDVIEAQLVESLMKAQYCKALYDH
IEARANLDYVVGKQVTDIIGGQR
>Mature_503_residues
MKAKMTPARILRPLFLCTLVCWLFGAATAWAQEASGDAQTPAPTTATPGTGALTLGQCIDLALEKNHSRLASRYGIEIAE
AQHRQALSGYWPQINAKANYSIMDEDPNFIFPAKTFQMPASTMTATTPLGPMPISIPASSYKIPEQKVKLMDRENFVVSL
NATLPLYTGGQVSAVVRQAEQGMKAAREEARRSDLQVVYDTTRYYYGAVLARELLQIGRDALTRMEVTLELTESLYTKGS
GKVKKTDYLRNKTVVEWLRSTIAILEANEQLARAALTNSMGMEWQNPVEPAPQELPYLPTRVELKELVSNAYSFNPDWAR
LEAGLEAAAAKIDETKSGHLPKIGLFGNLNRIENSYSKGMVTPDNRTSWAIGIGLELPLFNGMRTTGQVREARARLEKMK
QQQFLLKEGIALQVKHIFIQLMSSQQQKAASQAAAASSEENRALNERAYQEELVETKDVIEAQLVESLMKAQYCKALYDH
IEARANLDYVVGKQVTDIIGGQR

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Attached To The Outer Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 55813; Mature: 55813

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAKMTPARILRPLFLCTLVCWLFGAATAWAQEASGDAQTPAPTTATPGTGALTLGQCID
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
LALEKNHSRLASRYGIEIAEAQHRQALSGYWPQINAKANYSIMDEDPNFIFPAKTFQMPA
HHHHCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCEEECCHHHCCCC
STMTATTPLGPMPISIPASSYKIPEQKVKLMDRENFVVSLNATLPLYTGGQVSAVVRQAE
HHHCCCCCCCCCCEECCCCCCCCCHHHHHHHCCCCEEEEEECCEEEECCCHHHHHHHHHH
QGMKAAREEARRSDLQVVYDTTRYYYGAVLARELLQIGRDALTRMEVTLELTESLYTKGS
HHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GKVKKTDYLRNKTVVEWLRSTIAILEANEQLARAALTNSMGMEWQNPVEPAPQELPYLPT
CCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
RVELKELVSNAYSFNPDWARLEAGLEAAAAKIDETKSGHLPKIGLFGNLNRIENSYSKGM
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHCCC
VTPDNRTSWAIGIGLELPLFNGMRTTGQVREARARLEKMKQQQFLLKEGIALQVKHIFIQ
CCCCCCCEEEEEECEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LMSSQQQKAASQAAAASSEENRALNERAYQEELVETKDVIEAQLVESLMKAQYCKALYDH
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEARANLDYVVGKQVTDIIGGQR
HHHHCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKAKMTPARILRPLFLCTLVCWLFGAATAWAQEASGDAQTPAPTTATPGTGALTLGQCID
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
LALEKNHSRLASRYGIEIAEAQHRQALSGYWPQINAKANYSIMDEDPNFIFPAKTFQMPA
HHHHCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCEEECCHHHCCCC
STMTATTPLGPMPISIPASSYKIPEQKVKLMDRENFVVSLNATLPLYTGGQVSAVVRQAE
HHHCCCCCCCCCCEECCCCCCCCCHHHHHHHCCCCEEEEEECCEEEECCCHHHHHHHHHH
QGMKAAREEARRSDLQVVYDTTRYYYGAVLARELLQIGRDALTRMEVTLELTESLYTKGS
HHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GKVKKTDYLRNKTVVEWLRSTIAILEANEQLARAALTNSMGMEWQNPVEPAPQELPYLPT
CCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
RVELKELVSNAYSFNPDWARLEAGLEAAAAKIDETKSGHLPKIGLFGNLNRIENSYSKGM
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHCCC
VTPDNRTSWAIGIGLELPLFNGMRTTGQVREARARLEKMKQQQFLLKEGIALQVKHIFIQ
CCCCCCCEEEEEECEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LMSSQQQKAASQAAAASSEENRALNERAYQEELVETKDVIEAQLVESLMKAQYCKALYDH
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEARANLDYVVGKQVTDIIGGQR
HHHHCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA