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The map label for this gene is htpG

Identifier: 118579799

GI number: 118579799

Start: 1459940

End: 1461877

Strand: Reverse

Name: htpG

Synonym: Ppro_1375

Alternate gene names: 118579799

Gene position: 1461877-1459940 (Counterclockwise)

Preceding gene: 118579800

Following gene: 118579798

Centisome position: 36.47

GC content: 59.6

Gene sequence:

>1938_bases
ATGTCCAAAACCACCAAACAGTTCCAGACCGAGGTTAAACAGCTGCTCGACCTGGTGATCCATTCGCTCTACTCCAACCG
CGACATCTTCCTGCGCGAGCTGATCTCAAATTCATCCGACGCCATCGACAAGATCCGCTTCGAAGCCCACTCCAACGAGG
AGCTTCTGGAGGGGAACAGCGACTGGAAGATCAAGCTGATCCCGGACAAGGACGCCGGCACCCTGACCATCCTTGATAAC
GGCATCGGCATGACCATGGCAGAGGTGGAGGAGAACATCGGCACCATCGCCCGCTCCGGAACCAAGGCCTTCATGCAGGC
GCTCAAAGACAAGTCCGCCACGGACAATCCCGAGTTGATCGGCCAGTTCGGGGTCGGCTTCTACGCCTCGTTCATGGTGG
CCGACCGGGTCATCCTGGAGACCCGCAAGGGGGGCACTGCCAGCGATGGCTGCCGCTGGGAATCCATCGGCGATGGCAGC
TACACCATCGAGGAGTGCAGCCTCGATCGGCGCGGCACGGAGATCGTCCTGCACTTAAAAGATGAGTTCAAGGAGTATCT
GGAGGAGTGGAAGATCCGCTCCATCGTCAAGAAGTACTCCGACTACATCCAGTATCCGGTGGTCATGGACATCACCCGCA
CCGAAACGCCCAAGGGGGTGGACGGCGAGGAGATCGAAGGGGCCGGCACCATCGAGAAGACCGTGGAAGAGACCTTGAAC
TCCATGAAGGCCATCTGGGCCCGCCCCAAGAGCGAGGTCACGGAGGAGGAATACCAGGAGTTCTACAAGCATATCTCCCA
CGACTTCGAAAACCCCTTCAACACCATCCACTTCTCGGCCGAGGGGATCAGCGAGTTCAAGGCCCTGATCTACCTCCCCG
CCAAGAAACCCTTCGACCTGTTCATGGCCGACCGCAAGAAGGGGCTGCAGCTGTACGTGAAGCGGGTCTTCATCACCGAC
CGCTGCGAAGAGCTGCTGCCCGACTACCTGCGCTTCGTCAAGGGGGTGGTGGACTCCAGCGACCTGCCGCTGAACGTCTC
CCGCGAGATCCTGCAGGAGGACGTACAGATCAAGCGCATCCAGAAGAGCCTGGTGGGCAAGATCCTCTCCACCCTGGCCG
AGGTCAAGGAGAAGAACTTCGACGAGTACGTGAACTTCTGGAAGGAGTTCGGCCCGGTGCTCAAGGAGGGACTGCACTTC
GACTACGCCAACAAGGAGAAGTTGCAGGAACTGGCGCTGTTCGAAAGCACCGCCACCGAGGCGGGGAGCTTCACCAGCCT
CAAGGAATACGTGGAGCGCATGCCCGAAGCCCAGCAGGAGATCTACTTCATCACCGGCGACAGCCGCGCCACCCTGAAAA
TCTCGCCCCATCTGGAGGCCTTCAAGGCCAAGGGATACGAGGTGCTCTTCCTGACCGATCCGGTTGACGAATGGGTGGTT
CAGGCCCTGACCGAGTACAAGGAGAAGAAGCTCAAGGCCGTTGACCGCGGCGACGTGGACCTGGACAGCGAGGAAGAGAA
GAAGGAGAAGGAAACCAAACAGGAAGAGGCCCGCAAGGAGTACGGCGACCTGATCTCCTTCATCAAGAGCCACCTGGAGG
ACAGGGTCAAGGACGCCCGCCTCTCCAAGCGCCTGACCGACAGCGCCTGCTGCCTGGTGGCCGACGAGTACGGCATCAAC
GCCAACATGGAGCGGATCCTGAAAGCCATGAACCAGCCGGTTCCCGACTCAAAGCGGGTGCTGGAGTTGAACCCGGATCA
CCCGATCATGAAGATCATGACCGAGATCTTCAGGGAGAACAAGGAGGATGCCCGCCTGACTGACTACGCCGACCTGCTCT
ACGATCAGGCCCTGCTGACGGAAGGCTCCCCCATCAAGGACCCCTTACGCTTCACCCGCCTGGTGAGTGAGCTGATGGTC
AAGGCCGCAACGAAATAG

Upstream 100 bases:

>100_bases
ACAGCGGATGACTTTCCGCGTGCCCCCCCTTGAAAAATAACCACCCGCTTATTATGTTGTAGCGTGCCATTTCCATTCGT
TTAAAGGAGAATCACGAGTC

Downstream 100 bases:

>100_bases
TCATTCAGAACCAGATCCCGGCTTCCAAGAGCCCGTGGCCCCGCGCCACGGGCTTTTTTCTGTTGTTTTTCACTAGTTGC
GCCCGGGTCGCGGAAAGGTT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 645; Mature: 644

Protein sequence:

>645_residues
MSKTTKQFQTEVKQLLDLVIHSLYSNRDIFLRELISNSSDAIDKIRFEAHSNEELLEGNSDWKIKLIPDKDAGTLTILDN
GIGMTMAEVEENIGTIARSGTKAFMQALKDKSATDNPELIGQFGVGFYASFMVADRVILETRKGGTASDGCRWESIGDGS
YTIEECSLDRRGTEIVLHLKDEFKEYLEEWKIRSIVKKYSDYIQYPVVMDITRTETPKGVDGEEIEGAGTIEKTVEETLN
SMKAIWARPKSEVTEEEYQEFYKHISHDFENPFNTIHFSAEGISEFKALIYLPAKKPFDLFMADRKKGLQLYVKRVFITD
RCEELLPDYLRFVKGVVDSSDLPLNVSREILQEDVQIKRIQKSLVGKILSTLAEVKEKNFDEYVNFWKEFGPVLKEGLHF
DYANKEKLQELALFESTATEAGSFTSLKEYVERMPEAQQEIYFITGDSRATLKISPHLEAFKAKGYEVLFLTDPVDEWVV
QALTEYKEKKLKAVDRGDVDLDSEEEKKEKETKQEEARKEYGDLISFIKSHLEDRVKDARLSKRLTDSACCLVADEYGIN
ANMERILKAMNQPVPDSKRVLELNPDHPIMKIMTEIFRENKEDARLTDYADLLYDQALLTEGSPIKDPLRFTRLVSELMV
KAATK

Sequences:

>Translated_645_residues
MSKTTKQFQTEVKQLLDLVIHSLYSNRDIFLRELISNSSDAIDKIRFEAHSNEELLEGNSDWKIKLIPDKDAGTLTILDN
GIGMTMAEVEENIGTIARSGTKAFMQALKDKSATDNPELIGQFGVGFYASFMVADRVILETRKGGTASDGCRWESIGDGS
YTIEECSLDRRGTEIVLHLKDEFKEYLEEWKIRSIVKKYSDYIQYPVVMDITRTETPKGVDGEEIEGAGTIEKTVEETLN
SMKAIWARPKSEVTEEEYQEFYKHISHDFENPFNTIHFSAEGISEFKALIYLPAKKPFDLFMADRKKGLQLYVKRVFITD
RCEELLPDYLRFVKGVVDSSDLPLNVSREILQEDVQIKRIQKSLVGKILSTLAEVKEKNFDEYVNFWKEFGPVLKEGLHF
DYANKEKLQELALFESTATEAGSFTSLKEYVERMPEAQQEIYFITGDSRATLKISPHLEAFKAKGYEVLFLTDPVDEWVV
QALTEYKEKKLKAVDRGDVDLDSEEEKKEKETKQEEARKEYGDLISFIKSHLEDRVKDARLSKRLTDSACCLVADEYGIN
ANMERILKAMNQPVPDSKRVLELNPDHPIMKIMTEIFRENKEDARLTDYADLLYDQALLTEGSPIKDPLRFTRLVSELMV
KAATK
>Mature_644_residues
SKTTKQFQTEVKQLLDLVIHSLYSNRDIFLRELISNSSDAIDKIRFEAHSNEELLEGNSDWKIKLIPDKDAGTLTILDNG
IGMTMAEVEENIGTIARSGTKAFMQALKDKSATDNPELIGQFGVGFYASFMVADRVILETRKGGTASDGCRWESIGDGSY
TIEECSLDRRGTEIVLHLKDEFKEYLEEWKIRSIVKKYSDYIQYPVVMDITRTETPKGVDGEEIEGAGTIEKTVEETLNS
MKAIWARPKSEVTEEEYQEFYKHISHDFENPFNTIHFSAEGISEFKALIYLPAKKPFDLFMADRKKGLQLYVKRVFITDR
CEELLPDYLRFVKGVVDSSDLPLNVSREILQEDVQIKRIQKSLVGKILSTLAEVKEKNFDEYVNFWKEFGPVLKEGLHFD
YANKEKLQELALFESTATEAGSFTSLKEYVERMPEAQQEIYFITGDSRATLKISPHLEAFKAKGYEVLFLTDPVDEWVVQ
ALTEYKEKKLKAVDRGDVDLDSEEEKKEKETKQEEARKEYGDLISFIKSHLEDRVKDARLSKRLTDSACCLVADEYGINA
NMERILKAMNQPVPDSKRVLELNPDHPIMKIMTEIFRENKEDARLTDYADLLYDQALLTEGSPIKDPLRFTRLVSELMVK
AATK

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI154146191, Length=676, Percent_Identity=40.5325443786982, Blast_Score=462, Evalue=1e-130,
Organism=Homo sapiens, GI20149594, Length=672, Percent_Identity=39.5833333333333, Blast_Score=462, Evalue=1e-130,
Organism=Homo sapiens, GI153792590, Length=676, Percent_Identity=40.5325443786982, Blast_Score=459, Evalue=1e-129,
Organism=Homo sapiens, GI4507677, Length=662, Percent_Identity=39.1238670694864, Blast_Score=441, Evalue=1e-123,
Organism=Homo sapiens, GI155722983, Length=650, Percent_Identity=33.8461538461538, Blast_Score=376, Evalue=1e-104,
Organism=Escherichia coli, GI1786679, Length=638, Percent_Identity=45.7680250783699, Blast_Score=569, Evalue=1e-163,
Organism=Caenorhabditis elegans, GI17559162, Length=658, Percent_Identity=42.4012158054711, Blast_Score=489, Evalue=1e-138,
Organism=Caenorhabditis elegans, GI17542208, Length=658, Percent_Identity=39.8176291793313, Blast_Score=432, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI115535205, Length=657, Percent_Identity=35.1598173515982, Blast_Score=347, Evalue=2e-95,
Organism=Caenorhabditis elegans, GI115535167, Length=438, Percent_Identity=38.1278538812785, Blast_Score=276, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6323840, Length=684, Percent_Identity=40.0584795321637, Blast_Score=462, Evalue=1e-131,
Organism=Saccharomyces cerevisiae, GI6325016, Length=688, Percent_Identity=40.406976744186, Blast_Score=457, Evalue=1e-129,
Organism=Drosophila melanogaster, GI17647529, Length=672, Percent_Identity=40.7738095238095, Blast_Score=498, Evalue=1e-141,
Organism=Drosophila melanogaster, GI21357739, Length=674, Percent_Identity=37.9821958456973, Blast_Score=422, Evalue=1e-118,
Organism=Drosophila melanogaster, GI24586016, Length=660, Percent_Identity=34.6969696969697, Blast_Score=377, Evalue=1e-104,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_PELPD (A1ANS1)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_901049.1
- ProteinModelPortal:   A1ANS1
- STRING:   A1ANS1
- GeneID:   4574521
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_1375
- eggNOG:   COG0326
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- PhylomeDB:   A1ANS1
- ProtClustDB:   PRK05218
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 73944; Mature: 73813

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTTKQFQTEVKQLLDLVIHSLYSNRDIFLRELISNSSDAIDKIRFEAHSNEELLEGNS
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCCHHHHCCCC
DWKIKLIPDKDAGTLTILDNGIGMTMAEVEENIGTIARSGTKAFMQALKDKSATDNPELI
CCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHH
GQFGVGFYASFMVADRVILETRKGGTASDGCRWESIGDGSYTIEECSLDRRGTEIVLHLK
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCHHHHCCCCCCCEEEEEEH
DEFKEYLEEWKIRSIVKKYSDYIQYPVVMDITRTETPKGVDGEEIEGAGTIEKTVEETLN
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
SMKAIWARPKSEVTEEEYQEFYKHISHDFENPFNTIHFSAEGISEFKALIYLPAKKPFDL
HHHHHHCCCHHHCCHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHEEEECCCCCHHH
FMADRKKGLQLYVKRVFITDRCEELLPDYLRFVKGVVDSSDLPLNVSREILQEDVQIKRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
QKSLVGKILSTLAEVKEKNFDEYVNFWKEFGPVLKEGLHFDYANKEKLQELALFESTATE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
AGSFTSLKEYVERMPEAQQEIYFITGDSRATLKISPHLEAFKAKGYEVLFLTDPVDEWVV
CCCHHHHHHHHHHCCCHHHCEEEEECCCEEEEEECCCHHHHHCCCEEEEEEECCHHHHHH
QALTEYKEKKLKAVDRGDVDLDSEEEKKEKETKQEEARKEYGDLISFIKSHLEDRVKDAR
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSKRLTDSACCLVADEYGINANMERILKAMNQPVPDSKRVLELNPDHPIMKIMTEIFREN
HHHHHCCCHHEEEECCCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHCC
KEDARLTDYADLLYDQALLTEGSPIKDPLRFTRLVSELMVKAATK
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKTTKQFQTEVKQLLDLVIHSLYSNRDIFLRELISNSSDAIDKIRFEAHSNEELLEGNS
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCCHHHHCCCC
DWKIKLIPDKDAGTLTILDNGIGMTMAEVEENIGTIARSGTKAFMQALKDKSATDNPELI
CCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHH
GQFGVGFYASFMVADRVILETRKGGTASDGCRWESIGDGSYTIEECSLDRRGTEIVLHLK
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCHHHHCCCCCCCEEEEEEH
DEFKEYLEEWKIRSIVKKYSDYIQYPVVMDITRTETPKGVDGEEIEGAGTIEKTVEETLN
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
SMKAIWARPKSEVTEEEYQEFYKHISHDFENPFNTIHFSAEGISEFKALIYLPAKKPFDL
HHHHHHCCCHHHCCHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHEEEECCCCCHHH
FMADRKKGLQLYVKRVFITDRCEELLPDYLRFVKGVVDSSDLPLNVSREILQEDVQIKRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
QKSLVGKILSTLAEVKEKNFDEYVNFWKEFGPVLKEGLHFDYANKEKLQELALFESTATE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
AGSFTSLKEYVERMPEAQQEIYFITGDSRATLKISPHLEAFKAKGYEVLFLTDPVDEWVV
CCCHHHHHHHHHHCCCHHHCEEEEECCCEEEEEECCCHHHHHCCCEEEEEEECCHHHHHH
QALTEYKEKKLKAVDRGDVDLDSEEEKKEKETKQEEARKEYGDLISFIKSHLEDRVKDAR
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSKRLTDSACCLVADEYGINANMERILKAMNQPVPDSKRVLELNPDHPIMKIMTEIFREN
HHHHHCCCHHEEEECCCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHCC
KEDARLTDYADLLYDQALLTEGSPIKDPLRFTRLVSELMVKAATK
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA