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The map label for this gene is cirA [H]

Identifier: 118579785

GI number: 118579785

Start: 1439524

End: 1441404

Strand: Direct

Name: cirA [H]

Synonym: Ppro_1358

Alternate gene names: 118579785

Gene position: 1439524-1441404 (Clockwise)

Preceding gene: 118579779

Following gene: 118579786

Centisome position: 35.92

GC content: 55.93

Gene sequence:

>1881_bases
ATGAATTTCATTAAACCGCCACATATTTTGAATTCCACACTATTTTCCCTTCTTCTGCTGTTTGGGGTGGCGCTTCCCTG
TGCTCGGGCTGAGAAGGCGGAGGATACCAGTGCGCTGTTCAGTGCTTGGCAGGAATCTTCATCCTCCAGCGCCACCCGCT
CCCCCAAGCCGCTCTCCCTGACAGCCGAAAATACGACAATAATCACCCAAAAGGAGATCGAGTCCCTCAACGCCCATACC
CTGGCCGACGTTCTGGCCACAATACCGGGCATCCAGACTCAAAATTATGGCGCAGCTGGTGGCCTTACAAGCGCCAGCAT
CCAGAGTGCGAGAAATTATCACGCGTTGGTGATGGTCGATGGGATCCCTCTAAACAACTTGAGTGAAAACTTCTCCGATG
TGGCCATGGTCCCGGCGCGGATCATCGAGCGGATCGAGGTTGTCAAGGGGGCGGCTTCCTCGGCCTGGGGACAGGCGCTG
GGCGGGGTGATCAACGTTATCACCAAAACGCCGGATCAGAGAAAGATTGGCGGTGTTGCAACCTCCTCCTATGGCGAGGG
GGCGACGGCCGACAGCAGCATTGAACTGAGCGGAACAGTTGACCGCCTGGGCTACTATTTCTCCGGCGGGTATCTGGGAT
TCAAGAATATCCCTCAACATATCACCACCGATTCCAATAACGTCTATGCCAAGCTGACCTACGATCTTTCGGACCAGGGA
CAGGTGTGGGGTACGTTCAGCCACAGTCATGGCAACCGCACCAATCTGTATATTCCCCGCTCCGACTGGGACCTGAGGGA
AGAACAGAAAACCACCTATATCTACGCCTCCCTCGGCATGCGGCGCAAACTGAGCGACAGCCTGGAGCTGGAAATCAGCG
GACGCCACGCCTACCGCAACTTTGATACCGTTGACACCAACATCAGCGACGGTTTGCCCTGGTCCTGGTCATCCCAGCCC
CGCCTGTTGACCAAGGAAAGGGTCTACGGCGCCAGCGCCAAGCTTATCTGGAGAGAGAGTAACAACCTGCTGGTTGTGGG
GGGAGATTTCGAGCATGTCAAGCTCTCCGCAAACGGGACTTATGACTATCCGCTCACGCCCGTTTCCCGTTCGGAAGACC
GCTGGGGTTTTTTCCTGAACGATACGTACACTATTGGCGACCTGGCAGTGACCGTCGGCGCCCGTTTCGACCGCCCCAAG
ACCACATCCGACCAGTTCAGCCCCTCCCTGGGCGTCACCTACAAACTGAGTGAAACCACCCTGCTGCGCGGCTACACGGC
GCGCGGCTACAGCCTCTGGGCGTTGACATTTGACGACACGCCGGCGGAAAAGGTCTGGACATCCCAAATTGGGATCGAAA
CTACTGCTGTCCCGTATCTGTGGCAGAAATTGACTCTCTTCCGCAACCAGATGTGGAGTTTTACGACTTGGAATGATAGC
GCCGGCATATACGAGTCGGACCGTCGTATGGCGTTGGGAGTGGAATATGAGATTCGCACCACGCCCGTTTTCAATACCTC
CATTGGAGCCGGTTACACCTTTACGGATACGGAGTTGTCAAAAAACCATGACTACGAGTCAGGAGTTCCCCGTCATACCG
TGCAGGTGTCGTTGCGCTACGATGACAAGACCTTTCGCGGTGTCCTGACCGGACGCCACATCTTCTGGAACACGCAACCA
AGTTCCGAACCGCTCTATAACGGTGACTATGGCGGTATGATCTGGGACCTGCACCTGGGCGCCACGTTGGTGAAGCGTGA
GGAGCGGTCGCTGGAAGTGTTCTTCTCCGGTCGCAATCTCTTCGACGGATCACAAACACCAAGTAATTATTGCGTCTATC
CCGGCCGCTGGTTCGAGGGTGGAGTGAGGGTACGGTTTTGA

Upstream 100 bases:

>100_bases
GACACGGGCATCACCCCCTTTCAATAAAATGTTTGTGTTCGTTCATACAGTCTGGACAAACGGCTTTTGAATCTGATATG
GTGCTGATTCGAACTATGCC

Downstream 100 bases:

>100_bases
GAATACTCATCGCTCTCATACTCGCCCTGGCGACCCTGCTCCCCTGCCTGGCCCAGGCCTACGACGTGCTGCTCTTGGTC
AGCCGCCGCGACCAGGCCTC

Product: TonB-dependent receptor, plug

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 626; Mature: 626

Protein sequence:

>626_residues
MNFIKPPHILNSTLFSLLLLFGVALPCARAEKAEDTSALFSAWQESSSSSATRSPKPLSLTAENTTIITQKEIESLNAHT
LADVLATIPGIQTQNYGAAGGLTSASIQSARNYHALVMVDGIPLNNLSENFSDVAMVPARIIERIEVVKGAASSAWGQAL
GGVINVITKTPDQRKIGGVATSSYGEGATADSSIELSGTVDRLGYYFSGGYLGFKNIPQHITTDSNNVYAKLTYDLSDQG
QVWGTFSHSHGNRTNLYIPRSDWDLREEQKTTYIYASLGMRRKLSDSLELEISGRHAYRNFDTVDTNISDGLPWSWSSQP
RLLTKERVYGASAKLIWRESNNLLVVGGDFEHVKLSANGTYDYPLTPVSRSEDRWGFFLNDTYTIGDLAVTVGARFDRPK
TTSDQFSPSLGVTYKLSETTLLRGYTARGYSLWALTFDDTPAEKVWTSQIGIETTAVPYLWQKLTLFRNQMWSFTTWNDS
AGIYESDRRMALGVEYEIRTTPVFNTSIGAGYTFTDTELSKNHDYESGVPRHTVQVSLRYDDKTFRGVLTGRHIFWNTQP
SSEPLYNGDYGGMIWDLHLGATLVKREERSLEVFFSGRNLFDGSQTPSNYCVYPGRWFEGGVRVRF

Sequences:

>Translated_626_residues
MNFIKPPHILNSTLFSLLLLFGVALPCARAEKAEDTSALFSAWQESSSSSATRSPKPLSLTAENTTIITQKEIESLNAHT
LADVLATIPGIQTQNYGAAGGLTSASIQSARNYHALVMVDGIPLNNLSENFSDVAMVPARIIERIEVVKGAASSAWGQAL
GGVINVITKTPDQRKIGGVATSSYGEGATADSSIELSGTVDRLGYYFSGGYLGFKNIPQHITTDSNNVYAKLTYDLSDQG
QVWGTFSHSHGNRTNLYIPRSDWDLREEQKTTYIYASLGMRRKLSDSLELEISGRHAYRNFDTVDTNISDGLPWSWSSQP
RLLTKERVYGASAKLIWRESNNLLVVGGDFEHVKLSANGTYDYPLTPVSRSEDRWGFFLNDTYTIGDLAVTVGARFDRPK
TTSDQFSPSLGVTYKLSETTLLRGYTARGYSLWALTFDDTPAEKVWTSQIGIETTAVPYLWQKLTLFRNQMWSFTTWNDS
AGIYESDRRMALGVEYEIRTTPVFNTSIGAGYTFTDTELSKNHDYESGVPRHTVQVSLRYDDKTFRGVLTGRHIFWNTQP
SSEPLYNGDYGGMIWDLHLGATLVKREERSLEVFFSGRNLFDGSQTPSNYCVYPGRWFEGGVRVRF
>Mature_626_residues
MNFIKPPHILNSTLFSLLLLFGVALPCARAEKAEDTSALFSAWQESSSSSATRSPKPLSLTAENTTIITQKEIESLNAHT
LADVLATIPGIQTQNYGAAGGLTSASIQSARNYHALVMVDGIPLNNLSENFSDVAMVPARIIERIEVVKGAASSAWGQAL
GGVINVITKTPDQRKIGGVATSSYGEGATADSSIELSGTVDRLGYYFSGGYLGFKNIPQHITTDSNNVYAKLTYDLSDQG
QVWGTFSHSHGNRTNLYIPRSDWDLREEQKTTYIYASLGMRRKLSDSLELEISGRHAYRNFDTVDTNISDGLPWSWSSQP
RLLTKERVYGASAKLIWRESNNLLVVGGDFEHVKLSANGTYDYPLTPVSRSEDRWGFFLNDTYTIGDLAVTVGARFDRPK
TTSDQFSPSLGVTYKLSETTLLRGYTARGYSLWALTFDDTPAEKVWTSQIGIETTAVPYLWQKLTLFRNQMWSFTTWNDS
AGIYESDRRMALGVEYEIRTTPVFNTSIGAGYTFTDTELSKNHDYESGVPRHTVQVSLRYDDKTFRGVLTGRHIFWNTQP
SSEPLYNGDYGGMIWDLHLGATLVKREERSLEVFFSGRNLFDGSQTPSNYCVYPGRWFEGGVRVRF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=426, Percent_Identity=26.2910798122066, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1790405, Length=236, Percent_Identity=29.2372881355932, Blast_Score=87, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 69696; Mature: 69696

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFIKPPHILNSTLFSLLLLFGVALPCARAEKAEDTSALFSAWQESSSSSATRSPKPLSL
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEE
TAENTTIITQKEIESLNAHTLADVLATIPGIQTQNYGAAGGLTSASIQSARNYHALVMVD
EECCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEEEC
GIPLNNLSENFSDVAMVPARIIERIEVVKGAASSAWGQALGGVINVITKTPDQRKIGGVA
CCCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHCCCEE
TSSYGEGATADSSIELSGTVDRLGYYFSGGYLGFKNIPQHITTDSNNVYAKLTYDLSDQG
ECCCCCCCCCCCCEEECCCHHHCCEEEECCEECCCCCCCCEECCCCCEEEEEEEEECCCC
QVWGTFSHSHGNRTNLYIPRSDWDLREEQKTTYIYASLGMRRKLSDSLELEISGRHAYRN
CEEEEEECCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCEEECC
FDTVDTNISDGLPWSWSSQPRLLTKERVYGASAKLIWRESNNLLVVGGDFEHVKLSANGT
CCCCCCCCCCCCCCCCCCCCCEEEHHHHCCCCEEEEEEECCCEEEECCCCEEEEEECCCE
YDYPLTPVSRSEDRWGFFLNDTYTIGDLAVTVGARFDRPKTTSDQFSPSLGVTYKLSETT
ECCCCCCCCCCCCCCEEEECCEEEECEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCE
LLRGYTARGYSLWALTFDDTPAEKVWTSQIGIETTAVPYLWQKLTLFRNQMWSFTTWNDS
EEEEEECCCEEEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEECCC
AGIYESDRRMALGVEYEIRTTPVFNTSIGAGYTFTDTELSKNHDYESGVPRHTVQVSLRY
CCCEECCCEEEEEEEEEEEECCEEECCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEEE
DDKTFRGVLTGRHIFWNTQPSSEPLYNGDYGGMIWDLHLGATLVKREERSLEVFFSGRNL
CCCCEEEEEECCEEEECCCCCCCCCCCCCCCCEEEEEECCCEEECCCCCCEEEEECCCCC
FDGSQTPSNYCVYPGRWFEGGVRVRF
CCCCCCCCCEEEECCCCCCCCEEEEC
>Mature Secondary Structure
MNFIKPPHILNSTLFSLLLLFGVALPCARAEKAEDTSALFSAWQESSSSSATRSPKPLSL
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEE
TAENTTIITQKEIESLNAHTLADVLATIPGIQTQNYGAAGGLTSASIQSARNYHALVMVD
EECCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEEEC
GIPLNNLSENFSDVAMVPARIIERIEVVKGAASSAWGQALGGVINVITKTPDQRKIGGVA
CCCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHCCCEE
TSSYGEGATADSSIELSGTVDRLGYYFSGGYLGFKNIPQHITTDSNNVYAKLTYDLSDQG
ECCCCCCCCCCCCEEECCCHHHCCEEEECCEECCCCCCCCEECCCCCEEEEEEEEECCCC
QVWGTFSHSHGNRTNLYIPRSDWDLREEQKTTYIYASLGMRRKLSDSLELEISGRHAYRN
CEEEEEECCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCEEECC
FDTVDTNISDGLPWSWSSQPRLLTKERVYGASAKLIWRESNNLLVVGGDFEHVKLSANGT
CCCCCCCCCCCCCCCCCCCCCEEEHHHHCCCCEEEEEEECCCEEEECCCCEEEEEECCCE
YDYPLTPVSRSEDRWGFFLNDTYTIGDLAVTVGARFDRPKTTSDQFSPSLGVTYKLSETT
ECCCCCCCCCCCCCCEEEECCEEEECEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCE
LLRGYTARGYSLWALTFDDTPAEKVWTSQIGIETTAVPYLWQKLTLFRNQMWSFTTWNDS
EEEEEECCCEEEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEECCC
AGIYESDRRMALGVEYEIRTTPVFNTSIGAGYTFTDTELSKNHDYESGVPRHTVQVSLRY
CCCEECCCEEEEEEEEEEEECCEEECCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEEE
DDKTFRGVLTGRHIFWNTQPSSEPLYNGDYGGMIWDLHLGATLVKREERSLEVFFSGRNL
CCCCEEEEEECCEEEECCCCCCCCCCCCCCCCEEEEEECCCEEECCCCCCEEEEECCCCC
FDGSQTPSNYCVYPGRWFEGGVRVRF
CCCCCCCCCEEEECCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]