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The map label for this gene is pheA [H]

Identifier: 118579773

GI number: 118579773

Start: 1426911

End: 1427990

Strand: Direct

Name: pheA [H]

Synonym: Ppro_1345

Alternate gene names: 118579773

Gene position: 1426911-1427990 (Clockwise)

Preceding gene: 118579771

Following gene: 118579774

Centisome position: 35.6

GC content: 58.98

Gene sequence:

>1080_bases
TTGCAGCAGAATACTCCGACAATTGAACAGCTTCGCGCCAGGATCGATGGTATCGACGACCAGATCGTGGCGCTCCTCAA
CGAACGTTCGCGGGTGGTCCTGGAGGTCGGTCGGCTCAAGTCCGGCAGCAACATGGATTTTCATGTGCCGGGGCGTGAAC
GCCAGATCTACGAGCGCCTGCTGAACGTAAACCCGGGGCCGTTCCCTAACGATGCCCTGCGCAGCGTCTACCGCGAGATC
ATCTCTGCCAGCCTCTCCCTCGAGTCGCCCATGAAAGTGGCTTTTCTTGGTCCCAAGGCGACCTTCAGCCATCTGGCGAC
TATGCAGCAATTCGGCCTTTCCGCCGAGTTGGTGCCACTCAAATCCATACCAGCTGTTTTCGAAGAGGTTGAAAAGGAAA
AGGCGCTCTACGGCGTGGTGCCGGTGGAGAACTCCACCGAGGGGGTCATCTCTCACACCCTGGACATGTTCGTGGACAGC
GGGCTCAAGATCACCGCCGAGATCCTGCTGGAGGTCCATCACGACCTCTTGTCGCGCACCGGTCGGTTGGAGGATGTCAA
GAAGGTCTACTCCCACGTTCAGCCCATAGCCCAGTGCCGCCAGTGGCTGGAGGATAACCTGCCCGGCATACCGGTGGTTG
ATGTGGCTTCCACCGCCGTGGCCGCCCAGATCGTCAGCGAAGACTACTCGGCCGCCGCCATCGCCAGCGAACTGGCGGCA
ACGCTCTACGACCTCAAGGTCGTCAGGAGCAGGATCGAGGACCAGGTCAACAACTTCACCCGATTTCTGGTTGTCAGCCG
CAAGGGGTGCGAACGCTCCGGAAACGATAAGACCTCGGTCCTCTTTTCGGTCAAGGACGAGCCGGGGATTCTCTTCCGCA
TGCTGGAACCCTTTGCCAAGCGCGGCATCAACCTCTCCAAGATCGAATCGCGCCCCTTCAAAAAGAAGGCCTGGGAGTAC
ATCTTTTTTCTCGACCTGTTCGGCCACTCATCCGATCCCCAGGTTGCGGAAGCGCTGGAAGAACTGCGGTTGTGCTGCCA
GTTCCTGAAAATCCTCGGGTCGTACCCGCGGTCAATGTAA

Upstream 100 bases:

>100_bases
GCCCCCGCCGGGCTGGATTCAAAATGGGTTGCTTTTTGGGTGGCAATGCACTACATTTATCCACCCGATTCAATTCCAAC
CTTGCGCCAGGCGGCCCCCA

Downstream 100 bases:

>100_bases
GGGGGCGACGCGGCATGTCCTGTATTATTGAGCGGCTGGCAATAGTCGGCGTGGGACTGATCGGCGGCTCCTTCGCACGC
GCGCTGCGCCAGGCCGGGGC

Product: chorismate mutase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MQQNTPTIEQLRARIDGIDDQIVALLNERSRVVLEVGRLKSGSNMDFHVPGRERQIYERLLNVNPGPFPNDALRSVYREI
ISASLSLESPMKVAFLGPKATFSHLATMQQFGLSAELVPLKSIPAVFEEVEKEKALYGVVPVENSTEGVISHTLDMFVDS
GLKITAEILLEVHHDLLSRTGRLEDVKKVYSHVQPIAQCRQWLEDNLPGIPVVDVASTAVAAQIVSEDYSAAAIASELAA
TLYDLKVVRSRIEDQVNNFTRFLVVSRKGCERSGNDKTSVLFSVKDEPGILFRMLEPFAKRGINLSKIESRPFKKKAWEY
IFFLDLFGHSSDPQVAEALEELRLCCQFLKILGSYPRSM

Sequences:

>Translated_359_residues
MQQNTPTIEQLRARIDGIDDQIVALLNERSRVVLEVGRLKSGSNMDFHVPGRERQIYERLLNVNPGPFPNDALRSVYREI
ISASLSLESPMKVAFLGPKATFSHLATMQQFGLSAELVPLKSIPAVFEEVEKEKALYGVVPVENSTEGVISHTLDMFVDS
GLKITAEILLEVHHDLLSRTGRLEDVKKVYSHVQPIAQCRQWLEDNLPGIPVVDVASTAVAAQIVSEDYSAAAIASELAA
TLYDLKVVRSRIEDQVNNFTRFLVVSRKGCERSGNDKTSVLFSVKDEPGILFRMLEPFAKRGINLSKIESRPFKKKAWEY
IFFLDLFGHSSDPQVAEALEELRLCCQFLKILGSYPRSM
>Mature_359_residues
MQQNTPTIEQLRARIDGIDDQIVALLNERSRVVLEVGRLKSGSNMDFHVPGRERQIYERLLNVNPGPFPNDALRSVYREI
ISASLSLESPMKVAFLGPKATFSHLATMQQFGLSAELVPLKSIPAVFEEVEKEKALYGVVPVENSTEGVISHTLDMFVDS
GLKITAEILLEVHHDLLSRTGRLEDVKKVYSHVQPIAQCRQWLEDNLPGIPVVDVASTAVAAQIVSEDYSAAAIASELAA
TLYDLKVVRSRIEDQVNNFTRFLVVSRKGCERSGNDKTSVLFSVKDEPGILFRMLEPFAKRGINLSKIESRPFKKKAWEY
IFFLDLFGHSSDPQVAEALEELRLCCQFLKILGSYPRSM

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=369, Percent_Identity=32.2493224932249, Blast_Score=174, Evalue=7e-45,
Organism=Saccharomyces cerevisiae, GI6324013, Length=336, Percent_Identity=27.9761904761905, Blast_Score=119, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 40206; Mature: 40206

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00857 PREPHENATE_DEHYDR_1 ; PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQNTPTIEQLRARIDGIDDQIVALLNERSRVVLEVGRLKSGSNMDFHVPGRERQIYERL
CCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCEEHHHHCCCCCCCCEEECCCHHHHHHHHH
LNVNPGPFPNDALRSVYREIISASLSLESPMKVAFLGPKATFSHLATMQQFGLSAELVPL
HCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEECCH
KSIPAVFEEVEKEKALYGVVPVENSTEGVISHTLDMFVDSGLKITAEILLEVHHDLLSRT
HHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
GRLEDVKKVYSHVQPIAQCRQWLEDNLPGIPVVDVASTAVAAQIVSEDYSAAAIASELAA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
TLYDLKVVRSRIEDQVNNFTRFLVVSRKGCERSGNDKTSVLFSVKDEPGILFRMLEPFAK
HHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHH
RGINLSKIESRPFKKKAWEYIFFLDLFGHSSDPQVAEALEELRLCCQFLKILGSYPRSM
CCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQQNTPTIEQLRARIDGIDDQIVALLNERSRVVLEVGRLKSGSNMDFHVPGRERQIYERL
CCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCEEHHHHCCCCCCCCEEECCCHHHHHHHHH
LNVNPGPFPNDALRSVYREIISASLSLESPMKVAFLGPKATFSHLATMQQFGLSAELVPL
HCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEECCH
KSIPAVFEEVEKEKALYGVVPVENSTEGVISHTLDMFVDSGLKITAEILLEVHHDLLSRT
HHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
GRLEDVKKVYSHVQPIAQCRQWLEDNLPGIPVVDVASTAVAAQIVSEDYSAAAIASELAA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
TLYDLKVVRSRIEDQVNNFTRFLVVSRKGCERSGNDKTSVLFSVKDEPGILFRMLEPFAK
HHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHH
RGINLSKIESRPFKKKAWEYIFFLDLFGHSSDPQVAEALEELRLCCQFLKILGSYPRSM
CCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]