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The map label for this gene is bioD [H]

Identifier: 118579606

GI number: 118579606

Start: 1228884

End: 1229615

Strand: Direct

Name: bioD [H]

Synonym: Ppro_1176

Alternate gene names: 118579606

Gene position: 1228884-1229615 (Clockwise)

Preceding gene: 118579605

Following gene: 118579607

Centisome position: 30.66

GC content: 66.39

Gene sequence:

>732_bases
ATGAGCAGGGGGATCTTCATAACCGGGACCGATACCGGTGTGGGCAAGACCATCGTGGCAGCCACCCTGGCCCGGCTGTT
GCGCATGAGGGGGGTCGATGTGGGGGTGATGAAGCCAGCCACCAGCGGCTGCCGTGAGGAACAGGGGCGCCTGGTGTCTG
ATGACGCCCTGCTGCTCTGCCGGGCCGCTGCCTGCGAGTGCGACGGAGACGTGGCTCCCTATCTGTTACGTGAGCCGCTG
GCGCCGTCTGAGGCGGCCCGCATCGACGGAGTGCGCATCGAGGCTGACCGGATCAGGGCCTGCTATGACCGCATCGCAGC
ACGGCACGATTTCGTGATCGTCGAGGGGGCCGGCGGGCTGATGGTGCCGCTGGCGGATCAGCTGCTGGCCACGGACCTGA
TCAAGCTGCTGGGGCTTCCGCTGGTGGTGGTGGCACGGCCGAACCTGGGGACCGTCAACCATACGCTCTTGACCTGCTTC
AGCGCGCATAAGCTGGGGCTGACTGTTGTCGGGGTGTTTGTTAATAACTTCCCCCAATCTCCGGATCTGGCAGAGCAGGG
GGCGCCGGGGCAGATCCAGGCCCTGTGCGGAGCGCCGCTCCTGGGGGTCTGGCCCCATCGTGACGAGCACGACCAGTTCC
TGGCGGTGGAACAGCTGGCCTTCTGGCTGAACGAACAGCCGGGAACCGGTGACCTGCTGCGAAAGCTGGGGGTGGGGCAG
GCGACTGCCTGA

Upstream 100 bases:

>100_bases
GCGGCATGATGACCGGTAATTACCTGACCACCCTGGGGCGGAAGCCGGAACAGGACCACCAGATGCTGGCTGATCTGGGC
ATGGGCGTGGGAGGGTGTTC

Downstream 100 bases:

>100_bases
AGGGCTGCCAGGGAACGCTATTTTTGGGGGGATGCTGAAATAATGACCGAGCAGGAACTTCTCGATTTCGACAGGGCGCA
CATTTGGCACCCCTATACCT

Product: dethiobiotin synthase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MSRGIFITGTDTGVGKTIVAATLARLLRMRGVDVGVMKPATSGCREEQGRLVSDDALLLCRAAACECDGDVAPYLLREPL
APSEAARIDGVRIEADRIRACYDRIAARHDFVIVEGAGGLMVPLADQLLATDLIKLLGLPLVVVARPNLGTVNHTLLTCF
SAHKLGLTVVGVFVNNFPQSPDLAEQGAPGQIQALCGAPLLGVWPHRDEHDQFLAVEQLAFWLNEQPGTGDLLRKLGVGQ
ATA

Sequences:

>Translated_243_residues
MSRGIFITGTDTGVGKTIVAATLARLLRMRGVDVGVMKPATSGCREEQGRLVSDDALLLCRAAACECDGDVAPYLLREPL
APSEAARIDGVRIEADRIRACYDRIAARHDFVIVEGAGGLMVPLADQLLATDLIKLLGLPLVVVARPNLGTVNHTLLTCF
SAHKLGLTVVGVFVNNFPQSPDLAEQGAPGQIQALCGAPLLGVWPHRDEHDQFLAVEQLAFWLNEQPGTGDLLRKLGVGQ
ATA
>Mature_242_residues
SRGIFITGTDTGVGKTIVAATLARLLRMRGVDVGVMKPATSGCREEQGRLVSDDALLLCRAAACECDGDVAPYLLREPLA
PSEAARIDGVRIEADRIRACYDRIAARHDFVIVEGAGGLMVPLADQLLATDLIKLLGLPLVVVARPNLGTVNHTLLTCFS
AHKLGLTVVGVFVNNFPQSPDLAEQGAPGQIQALCGAPLLGVWPHRDEHDQFLAVEQLAFWLNEQPGTGDLLRKLGVGQA
TA

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=214, Percent_Identity=33.1775700934579, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI87081944, Length=218, Percent_Identity=30.7339449541284, Blast_Score=76, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324385, Length=202, Percent_Identity=33.1683168316832, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 25836; Mature: 25705

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRGIFITGTDTGVGKTIVAATLARLLRMRGVDVGVMKPATSGCREEQGRLVSDDALLLC
CCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHCCCEECCCHHHHH
RAAACECDGDVAPYLLREPLAPSEAARIDGVRIEADRIRACYDRIAARHDFVIVEGAGGL
HHHHCCCCCCCCHHHHHCCCCCCCHHHCCCEEECHHHHHHHHHHHHCCCCEEEEECCCCE
MVPLADQLLATDLIKLLGLPLVVVARPNLGTVNHTLLTCFSAHKLGLTVVGVFVNNFPQS
EHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCHHHEEHHHHCCCCC
PDLAEQGAPGQIQALCGAPLLGVWPHRDEHDQFLAVEQLAFWLNEQPGTGDLLRKLGVGQ
CCHHHCCCCCCCHHHHCCCEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCC
ATA
CCC
>Mature Secondary Structure 
SRGIFITGTDTGVGKTIVAATLARLLRMRGVDVGVMKPATSGCREEQGRLVSDDALLLC
CCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHCCCEECCCHHHHH
RAAACECDGDVAPYLLREPLAPSEAARIDGVRIEADRIRACYDRIAARHDFVIVEGAGGL
HHHHCCCCCCCCHHHHHCCCCCCCHHHCCCEEECHHHHHHHHHHHHCCCCEEEEECCCCE
MVPLADQLLATDLIKLLGLPLVVVARPNLGTVNHTLLTCFSAHKLGLTVVGVFVNNFPQS
EHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCHHHEEHHHHCCCCC
PDLAEQGAPGQIQALCGAPLLGVWPHRDEHDQFLAVEQLAFWLNEQPGTGDLLRKLGVGQ
CCHHHCCCCCCCHHHHCCCEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCC
ATA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA