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The map label for this gene is rnr [H]

Identifier: 118579602

GI number: 118579602

Start: 1224272

End: 1226605

Strand: Reverse

Name: rnr [H]

Synonym: Ppro_1172

Alternate gene names: 118579602

Gene position: 1226605-1224272 (Counterclockwise)

Preceding gene: 118579610

Following gene: 118579599

Centisome position: 30.6

GC content: 65.9

Gene sequence:

>2334_bases
ATGCAGATTTCCAAGAAAAACATACTCGCCTTTCTCAAGCAGCAGGACGGAGCCATCCACTTCGCCGGAATCCTGCGCCA
GTTCGGCGGTCGCCACGTAAAGAACGAACTGAAACGCATGCTGGATGACATGGCCCAAGACGGCGAACTGGTCAGATTCA
GGGGCAACAGCTATGCCCTGGCAAGCGCGGCAACCAGCATCCGCGGAAAGCTCTCCAGCCACCGGGACGGCTACGGCTTC
GTCACCCCCCAGGGGGGGGGCGAGGACATTTTCATCCCCCAGCGCCACATGAGGGGCGCCATGCATGGCGACACCGTGGA
GGTGCATGCAGAACGAAGCCGCATGGGGGGGGGCAAGTTCGAAGGGCGCATCACCAGCGTAGTGGAGCGGGGGGTGAGCC
GCGTGGTGGGGCGCTACGAGGAGACCAGGCGCGGCGCCATCGTCATCCCCGAAGAGACCCGCCTCAACCTGGTCATCGCC
ATCCCGCCCAAGGGACGCGGCCTGGCCCAGGACGGCCAGCAGGTGGTGGTGGAGCTCTCCTCCTACCCCGTGGGCGGCCG
GCCGGCAGAGGGAAATGTGGTGGAGGTGCTGGGCTGGCCCGACGACCCCGAGGTGGAGGTGCAGTCGGCCATCCGACGCT
TCGACCTGCCGCACGTCTTCGCCCCCGACACCCTGGCAGAGGCCGAGGCGATCCCCGAAACCGTGCCGGCACAAGAGCTG
GCCGGGCGGGTGGATCTGCGTCCACTGGCCACCGTGACCATCGACGGCGAGACGGCCCGCGATTTCGACGACGCCGTCTC
CCTGCGACGTGAGGGGGACAATTTCCGGCTGTGGGTTTCCATCGCCGACGTGTCCCATTACGTCAGGCCGGACAGCCCCC
TGGACCGCGACGCCTACCTGCGCGGCACATCGGTCTACTTCCCCGACCGCTGCATCCCCATGCTGCCGGAGCGGCTCTCC
AACGGCATCTGTTCCCTCAACCCGGGGGTGGAGCGCCTGACCATGACCGCCGAGATGCTCTTCGACAGGGATGGCAGCAT
GCTGGAATCGTCCTTCTACCCCGGCATCATCGCAAGCGCGGCCCGGCTGACCTACACCCAGGTGAAGCGGGTCATCGTGG
ACCAAGACCGGGAGACGGCCGACAGCCTGGGGACGGTGACGCCCATGCTGCTGGAGATGAAGGAGCTGGCACTGATCCTG
ATGGGGATGCGCCGCAAACGGGGGAGCATCGACTTCGACCTGCCCGAATCGGAGGTCATCATCGGCCTGACCGGCCTGAC
CGAGGGGATCGTGCGCGCGGAGCGCACCCTGGCCCACCAGCTGATCGAGGAGTTCATGCTGGCGGCCAACGAGGCGGTGG
CCCTGTTCATTGCGGAAAAGGGCATCCCCCTGCTCTACCGCATCCACGAGAACCCGGACCCGGCCAAGCTGATCAACTTC
CAGGAGTTCGCCTTCGGCTTCGGCTACGAGTTCCCCCTGAAGGAGGAGCGGGTCAATCCGGCCGACCTGCAACGCCTTTT
GGAGAGTGCAGCAGGACGTCCCGAGGAGCGGATGATCAACTACGCCCTCTTGCGTTGCATGAAGCAGGCCCGCTATGCGG
CCGAGAACCTGCACCACTTCGGACTGGCCTCCCGCTGCTACTGCCACTTCACCTCCCCCATCCGCCGCTACCCCGACCTG
GTGGTGCACCGCATCCTTAAAGCGCTCCTGGCCCTGGCCGAAAACAGGGGGAGCAAACAGGCCGAGAAGCGGCTCTCCCT
GGCGACCCACAACCTGTCCGAGGTCGGCGAGCACACCAGTAAGCGCGAACGGGTGGCCATGGAGGCGGAACGGGACATCG
TGGAACTGAAGAAGGCGCAGTTCATGCAACAGCACCTGGGTGAGGAATTCGACGGATTCATCACCGGCGTGACCGGCTTC
GGCTTTTTCGTGGAACTGGAGGAACTGTTCGTGGAGGGGTTGGTGCACGTCTCCACCCTGGACGACGACCTCTACACCTT
CGTGGAAAACCGCCATTCCCTGGTCGGCCGCAACCGGGGGCGGGTGCTGCGCATCGGGGACAGGGCGCGGGTGCGGGTGG
CATCGGTCTCCCCGGCAACAAGGAGGATCGAGTTCGTGCTCGTGGGGCACGCATCATCCACGCCCCAGATGCCACTCACG
ACCGCAGGGGACGGGGAATTCCCACGCACCCCCATCAGGGGCAAGCGCCTGCCGGGGCAGGGCCGCGAAAGGAACGCCGA
GGGAACGAAACCCTCCCCAGCGGCCGGCAGGCGTGAGGGGCAAAAGCGGACGAAAAAGGGGGCCGTCCGCACGGGGGGCA
GGAAACGGCGCTGA

Upstream 100 bases:

>100_bases
CATATCCTGTGGGGATGAAATTGGTCGCAATATGCGGCGGAAAAGCATATCATCCCCCGAACAACGGCACAACAGAACAC
GCGCTACCCGGAAGGAATCC

Downstream 100 bases:

>100_bases
GGTCAGCCAGCCGGCACAGGGGGAGCAGCGCCTTCCCGCCCCTGGCCATCCAGCACCTCCCGCAGCTTCCTGGCCAGGGA
GCGCGGCGAGAGCGGCTTCT

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 777; Mature: 777

Protein sequence:

>777_residues
MQISKKNILAFLKQQDGAIHFAGILRQFGGRHVKNELKRMLDDMAQDGELVRFRGNSYALASAATSIRGKLSSHRDGYGF
VTPQGGGEDIFIPQRHMRGAMHGDTVEVHAERSRMGGGKFEGRITSVVERGVSRVVGRYEETRRGAIVIPEETRLNLVIA
IPPKGRGLAQDGQQVVVELSSYPVGGRPAEGNVVEVLGWPDDPEVEVQSAIRRFDLPHVFAPDTLAEAEAIPETVPAQEL
AGRVDLRPLATVTIDGETARDFDDAVSLRREGDNFRLWVSIADVSHYVRPDSPLDRDAYLRGTSVYFPDRCIPMLPERLS
NGICSLNPGVERLTMTAEMLFDRDGSMLESSFYPGIIASAARLTYTQVKRVIVDQDRETADSLGTVTPMLLEMKELALIL
MGMRRKRGSIDFDLPESEVIIGLTGLTEGIVRAERTLAHQLIEEFMLAANEAVALFIAEKGIPLLYRIHENPDPAKLINF
QEFAFGFGYEFPLKEERVNPADLQRLLESAAGRPEERMINYALLRCMKQARYAAENLHHFGLASRCYCHFTSPIRRYPDL
VVHRILKALLALAENRGSKQAEKRLSLATHNLSEVGEHTSKRERVAMEAERDIVELKKAQFMQQHLGEEFDGFITGVTGF
GFFVELEELFVEGLVHVSTLDDDLYTFVENRHSLVGRNRGRVLRIGDRARVRVASVSPATRRIEFVLVGHASSTPQMPLT
TAGDGEFPRTPIRGKRLPGQGRERNAEGTKPSPAAGRREGQKRTKKGAVRTGGRKRR

Sequences:

>Translated_777_residues
MQISKKNILAFLKQQDGAIHFAGILRQFGGRHVKNELKRMLDDMAQDGELVRFRGNSYALASAATSIRGKLSSHRDGYGF
VTPQGGGEDIFIPQRHMRGAMHGDTVEVHAERSRMGGGKFEGRITSVVERGVSRVVGRYEETRRGAIVIPEETRLNLVIA
IPPKGRGLAQDGQQVVVELSSYPVGGRPAEGNVVEVLGWPDDPEVEVQSAIRRFDLPHVFAPDTLAEAEAIPETVPAQEL
AGRVDLRPLATVTIDGETARDFDDAVSLRREGDNFRLWVSIADVSHYVRPDSPLDRDAYLRGTSVYFPDRCIPMLPERLS
NGICSLNPGVERLTMTAEMLFDRDGSMLESSFYPGIIASAARLTYTQVKRVIVDQDRETADSLGTVTPMLLEMKELALIL
MGMRRKRGSIDFDLPESEVIIGLTGLTEGIVRAERTLAHQLIEEFMLAANEAVALFIAEKGIPLLYRIHENPDPAKLINF
QEFAFGFGYEFPLKEERVNPADLQRLLESAAGRPEERMINYALLRCMKQARYAAENLHHFGLASRCYCHFTSPIRRYPDL
VVHRILKALLALAENRGSKQAEKRLSLATHNLSEVGEHTSKRERVAMEAERDIVELKKAQFMQQHLGEEFDGFITGVTGF
GFFVELEELFVEGLVHVSTLDDDLYTFVENRHSLVGRNRGRVLRIGDRARVRVASVSPATRRIEFVLVGHASSTPQMPLT
TAGDGEFPRTPIRGKRLPGQGRERNAEGTKPSPAAGRREGQKRTKKGAVRTGGRKRR
>Mature_777_residues
MQISKKNILAFLKQQDGAIHFAGILRQFGGRHVKNELKRMLDDMAQDGELVRFRGNSYALASAATSIRGKLSSHRDGYGF
VTPQGGGEDIFIPQRHMRGAMHGDTVEVHAERSRMGGGKFEGRITSVVERGVSRVVGRYEETRRGAIVIPEETRLNLVIA
IPPKGRGLAQDGQQVVVELSSYPVGGRPAEGNVVEVLGWPDDPEVEVQSAIRRFDLPHVFAPDTLAEAEAIPETVPAQEL
AGRVDLRPLATVTIDGETARDFDDAVSLRREGDNFRLWVSIADVSHYVRPDSPLDRDAYLRGTSVYFPDRCIPMLPERLS
NGICSLNPGVERLTMTAEMLFDRDGSMLESSFYPGIIASAARLTYTQVKRVIVDQDRETADSLGTVTPMLLEMKELALIL
MGMRRKRGSIDFDLPESEVIIGLTGLTEGIVRAERTLAHQLIEEFMLAANEAVALFIAEKGIPLLYRIHENPDPAKLINF
QEFAFGFGYEFPLKEERVNPADLQRLLESAAGRPEERMINYALLRCMKQARYAAENLHHFGLASRCYCHFTSPIRRYPDL
VVHRILKALLALAENRGSKQAEKRLSLATHNLSEVGEHTSKRERVAMEAERDIVELKKAQFMQQHLGEEFDGFITGVTGF
GFFVELEELFVEGLVHVSTLDDDLYTFVENRHSLVGRNRGRVLRIGDRARVRVASVSPATRRIEFVLVGHASSTPQMPLT
TAGDGEFPRTPIRGKRLPGQGRERNAEGTKPSPAAGRREGQKRTKKGAVRTGGRKRR

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=625, Percent_Identity=27.36, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI190014623, Length=625, Percent_Identity=27.36, Blast_Score=191, Evalue=3e-48,
Organism=Homo sapiens, GI134288890, Length=454, Percent_Identity=29.7356828193833, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI19115966, Length=664, Percent_Identity=26.2048192771084, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI219521928, Length=664, Percent_Identity=26.2048192771084, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI156105695, Length=220, Percent_Identity=28.1818181818182, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI156105693, Length=220, Percent_Identity=28.1818181818182, Blast_Score=78, Evalue=4e-14,
Organism=Escherichia coli, GI87082383, Length=677, Percent_Identity=42.2451994091581, Blast_Score=503, Evalue=1e-143,
Organism=Escherichia coli, GI1787542, Length=661, Percent_Identity=27.3827534039334, Blast_Score=163, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI212645896, Length=502, Percent_Identity=29.4820717131474, Blast_Score=177, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17553506, Length=509, Percent_Identity=28.6836935166994, Blast_Score=159, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6324552, Length=578, Percent_Identity=26.9896193771626, Blast_Score=158, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6320499, Length=433, Percent_Identity=24.7113163972286, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24649634, Length=616, Percent_Identity=29.3831168831169, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI19922976, Length=366, Percent_Identity=31.1475409836066, Blast_Score=151, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24654597, Length=366, Percent_Identity=31.1475409836066, Blast_Score=151, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24654592, Length=366, Percent_Identity=31.1475409836066, Blast_Score=151, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 86617; Mature: 86617

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS50126 S1 ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQISKKNILAFLKQQDGAIHFAGILRQFGGRHVKNELKRMLDDMAQDGELVRFRGNSYAL
CCCCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECCCCEEE
ASAATSIRGKLSSHRDGYGFVTPQGGGEDIFIPQRHMRGAMHGDTVEVHAERSRMGGGKF
HHHHHHHHHHHHCCCCCCEEECCCCCCCCEECCHHHHCCCCCCCEEEEEEHHHHCCCCCC
EGRITSVVERGVSRVVGRYEETRRGAIVIPEETRLNLVIAIPPKGRGLAQDGQQVVVELS
CHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCCCCCCCCCCCEEEEECC
SYPVGGRPAEGNVVEVLGWPDDPEVEVQSAIRRFDLPHVFAPDTLAEAEAIPETVPAQEL
CCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCHHHH
AGRVDLRPLATVTIDGETARDFDDAVSLRREGDNFRLWVSIADVSHYVRPDSPLDRDAYL
CCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEEEECHHHHCCCCCCCCCCCEE
RGTSVYFPDRCIPMLPERLSNGICSLNPGVERLTMTAEMLFDRDGSMLESSFYPGIIASA
CCCEEECCCCCHHHHHHHHCCCCEECCCCHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHH
ARLTYTQVKRVIVDQDRETADSLGTVTPMLLEMKELALILMGMRRKRGSIDFDLPESEVI
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
IGLTGLTEGIVRAERTLAHQLIEEFMLAANEAVALFIAEKGIPLLYRIHENPDPAKLINF
EEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEECCCCCHHHHCCH
QEFAFGFGYEFPLKEERVNPADLQRLLESAAGRPEERMINYALLRCMKQARYAAENLHHF
HHHHHHCCCCCCCHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GLASRCYCHFTSPIRRYPDLVVHRILKALLALAENRGSKQAEKRLSLATHNLSEVGEHTS
CCHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHH
KRERVAMEAERDIVELKKAQFMQQHLGEEFDGFITGVTGFGFFVELEELFVEGLVHVSTL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEHHHHHHHHHHHHHHHHHHHHHEECC
DDDLYTFVENRHSLVGRNRGRVLRIGDRARVRVASVSPATRRIEFVLVGHASSTPQMPLT
CHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCCCCEEEEEEEEECCCCCCCCCEE
TAGDGEFPRTPIRGKRLPGQGRERNAEGTKPSPAAGRREGQKRTKKGAVRTGGRKRR
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MQISKKNILAFLKQQDGAIHFAGILRQFGGRHVKNELKRMLDDMAQDGELVRFRGNSYAL
CCCCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECCCCEEE
ASAATSIRGKLSSHRDGYGFVTPQGGGEDIFIPQRHMRGAMHGDTVEVHAERSRMGGGKF
HHHHHHHHHHHHCCCCCCEEECCCCCCCCEECCHHHHCCCCCCCEEEEEEHHHHCCCCCC
EGRITSVVERGVSRVVGRYEETRRGAIVIPEETRLNLVIAIPPKGRGLAQDGQQVVVELS
CHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCCCCCCCCCCCEEEEECC
SYPVGGRPAEGNVVEVLGWPDDPEVEVQSAIRRFDLPHVFAPDTLAEAEAIPETVPAQEL
CCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCHHHH
AGRVDLRPLATVTIDGETARDFDDAVSLRREGDNFRLWVSIADVSHYVRPDSPLDRDAYL
CCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEEEECHHHHCCCCCCCCCCCEE
RGTSVYFPDRCIPMLPERLSNGICSLNPGVERLTMTAEMLFDRDGSMLESSFYPGIIASA
CCCEEECCCCCHHHHHHHHCCCCEECCCCHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHH
ARLTYTQVKRVIVDQDRETADSLGTVTPMLLEMKELALILMGMRRKRGSIDFDLPESEVI
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
IGLTGLTEGIVRAERTLAHQLIEEFMLAANEAVALFIAEKGIPLLYRIHENPDPAKLINF
EEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEECCCCCHHHHCCH
QEFAFGFGYEFPLKEERVNPADLQRLLESAAGRPEERMINYALLRCMKQARYAAENLHHF
HHHHHHCCCCCCCHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GLASRCYCHFTSPIRRYPDLVVHRILKALLALAENRGSKQAEKRLSLATHNLSEVGEHTS
CCHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHH
KRERVAMEAERDIVELKKAQFMQQHLGEEFDGFITGVTGFGFFVELEELFVEGLVHVSTL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEHHHHHHHHHHHHHHHHHHHHHEECC
DDDLYTFVENRHSLVGRNRGRVLRIGDRARVRVASVSPATRRIEFVLVGHASSTPQMPLT
CHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCCCCEEEEEEEEECCCCCCCCCEE
TAGDGEFPRTPIRGKRLPGQGRERNAEGTKPSPAAGRREGQKRTKKGAVRTGGRKRR
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]