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The map label for this gene is yhdR [H]

Identifier: 118579479

GI number: 118579479

Start: 1096212

End: 1097408

Strand: Reverse

Name: yhdR [H]

Synonym: Ppro_1046

Alternate gene names: 118579479

Gene position: 1097408-1096212 (Counterclockwise)

Preceding gene: 118579484

Following gene: 118579478

Centisome position: 27.38

GC content: 64.08

Gene sequence:

>1197_bases
ATGGCCATTGCCACCAAGATCGCCAGCCACATCTCAAAATCTTCCTGGATCCGCAGGATGTTCGAGGAGGGAGAGCGCCT
GCGTCGGGAGTTCGGCGACGAGAGCGTCTACGACTTCACCCTGGGCAATCCGGATGTGGAGCCTCCCCAGGCATTCCAGG
AGGAACTGCTGGCACTGGCTCGGAATCCGCTGCCCGGCATGCACCGTTACATGAACAACGCCGGCTACCCCGAGACCCGG
GCCGCCGTTGCCGCCAAACTAGCCAGGGACTCGGGCATCGACCTGACCGCCGAGCACGTGATCATGACCTGCGGCGCTGG
CGGGGCGCTGAACGTGGTGCTCAAGACCATCCTCAACCCGGGCGAGGAGGTGATCATCCTGGCCCCCTATTTCGTGGAGT
ACAAATTCTACATCGACAACCACGGCGGCGTACCGGTGCCGGTCTGGACCGATCACCAGACGTTCCAGCTGGACATCGAA
GCCATAGAACAGGCCATAACCCTCAAGACCCGCGCCATCCTGATCTGCTCCCCCAACAACCCCACCGGCGTGATCTACCC
CGCCGAGAGCCTGGCCAGGCTGGGAGAGGTGGTGAAGAAGGTGCACAAGCGCAACGGCCACCTGATCTACGTCATCTCCG
ACGAGCCCTACGCGCGCATCGCCTATGACGGCAAGCAGGTACCCAACATCTTCCCGCTGATCGAGAGTTCCGTCATCGTC
ACCTCCCACAGCAAGGACCTGGCCCTGCCGGGAGAGCGCATCGGCTACCTGGCGGCCAACCCGCGTATGGACACGGTCAT
GCAGTTCATGGCCGGGGCGGTGTTCAGCAACCGCGTGCTCGGCTTCGTCAACGCGCCGGCGCTGATGCAGCGGCTGGTGA
CCAATCTGCAGGACGAGTCGGTGGACATCGCCGCCTACCAGGACAAACGGGACCTGCTGGTACGGGAGCTGACCGCCCTG
GGGTTCAAGATGGTCATACCGGACGGCGCCTTCTACCTCTTCCCCCAATCCCCCCTGGCCGACGACGTGGCCTTCGTCAA
GCTGGCCCAGAAGCACCATATCCTGCTGGTTCCGGGGGCCGGTTTCGGCGCGCCCGGATTCTTCAGGATCGCCTACTGCG
TGGACCGGGCGGTCATCGAGCGGAGCCTGCCGGCATGGGCCGGGCTGGCACAGGAGGCCGGGCTGAAAGCGCAGTAA

Upstream 100 bases:

>100_bases
AGGCCAGGGGGATGGAGGGGATTTTCCATTGAGTTCTCCCGGTTTCGGTGTGTATAGTGTCGGGCATCATACCAGAATAC
ATGCCTCGGAGGGAACAGCC

Downstream 100 bases:

>100_bases
AACGTGTCTGTTCGTCCGGGGCGGCGCGCGTCGTTCGCCGCCCCGGACGCCGCTATCCCGCAGCCCTGTCTCCCTCCCGG
CACCACCATCGGCACCTGTT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MAIATKIASHISKSSWIRRMFEEGERLRREFGDESVYDFTLGNPDVEPPQAFQEELLALARNPLPGMHRYMNNAGYPETR
AAVAAKLARDSGIDLTAEHVIMTCGAGGALNVVLKTILNPGEEVIILAPYFVEYKFYIDNHGGVPVPVWTDHQTFQLDIE
AIEQAITLKTRAILICSPNNPTGVIYPAESLARLGEVVKKVHKRNGHLIYVISDEPYARIAYDGKQVPNIFPLIESSVIV
TSHSKDLALPGERIGYLAANPRMDTVMQFMAGAVFSNRVLGFVNAPALMQRLVTNLQDESVDIAAYQDKRDLLVRELTAL
GFKMVIPDGAFYLFPQSPLADDVAFVKLAQKHHILLVPGAGFGAPGFFRIAYCVDRAVIERSLPAWAGLAQEAGLKAQ

Sequences:

>Translated_398_residues
MAIATKIASHISKSSWIRRMFEEGERLRREFGDESVYDFTLGNPDVEPPQAFQEELLALARNPLPGMHRYMNNAGYPETR
AAVAAKLARDSGIDLTAEHVIMTCGAGGALNVVLKTILNPGEEVIILAPYFVEYKFYIDNHGGVPVPVWTDHQTFQLDIE
AIEQAITLKTRAILICSPNNPTGVIYPAESLARLGEVVKKVHKRNGHLIYVISDEPYARIAYDGKQVPNIFPLIESSVIV
TSHSKDLALPGERIGYLAANPRMDTVMQFMAGAVFSNRVLGFVNAPALMQRLVTNLQDESVDIAAYQDKRDLLVRELTAL
GFKMVIPDGAFYLFPQSPLADDVAFVKLAQKHHILLVPGAGFGAPGFFRIAYCVDRAVIERSLPAWAGLAQEAGLKAQ
>Mature_397_residues
AIATKIASHISKSSWIRRMFEEGERLRREFGDESVYDFTLGNPDVEPPQAFQEELLALARNPLPGMHRYMNNAGYPETRA
AVAAKLARDSGIDLTAEHVIMTCGAGGALNVVLKTILNPGEEVIILAPYFVEYKFYIDNHGGVPVPVWTDHQTFQLDIEA
IEQAITLKTRAILICSPNNPTGVIYPAESLARLGEVVKKVHKRNGHLIYVISDEPYARIAYDGKQVPNIFPLIESSVIVT
SHSKDLALPGERIGYLAANPRMDTVMQFMAGAVFSNRVLGFVNAPALMQRLVTNLQDESVDIAAYQDKRDLLVRELTALG
FKMVIPDGAFYLFPQSPLADDVAFVKLAQKHHILLVPGAGFGAPGFFRIAYCVDRAVIERSLPAWAGLAQEAGLKAQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=373, Percent_Identity=26.0053619302949, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI56713256, Length=373, Percent_Identity=26.0053619302949, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI95147551, Length=328, Percent_Identity=25, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI169881279, Length=328, Percent_Identity=25, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4507369, Length=365, Percent_Identity=23.5616438356164, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1786816, Length=346, Percent_Identity=26.878612716763, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788627, Length=387, Percent_Identity=26.6149870801034, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788722, Length=384, Percent_Identity=23.4375, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790797, Length=352, Percent_Identity=25.5681818181818, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994476, Length=362, Percent_Identity=24.8618784530387, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI71994472, Length=362, Percent_Identity=24.8618784530387, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17567663, Length=314, Percent_Identity=26.4331210191083, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17567369, Length=350, Percent_Identity=24.8571428571429, Blast_Score=86, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6322401, Length=382, Percent_Identity=24.3455497382199, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28573069, Length=337, Percent_Identity=24.6290801186944, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24646114, Length=337, Percent_Identity=24.6290801186944, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI28573067, Length=337, Percent_Identity=24.6290801186944, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI28573065, Length=337, Percent_Identity=24.6290801186944, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI18859735, Length=339, Percent_Identity=23.598820058997, Blast_Score=82, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43829; Mature: 43698

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIATKIASHISKSSWIRRMFEEGERLRREFGDESVYDFTLGNPDVEPPQAFQEELLALA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
RNPLPGMHRYMNNAGYPETRAAVAAKLARDSGIDLTAEHVIMTCGAGGALNVVLKTILNP
CCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEECEEEEECCCCCHHHHHHHHHHCC
GEEVIILAPYFVEYKFYIDNHGGVPVPVWTDHQTFQLDIEAIEQAITLKTRAILICSPNN
CCCEEEEEEEEEEEEEEEECCCCCCCEEECCCCEEEEEHHHHHHHHEEEEEEEEEECCCC
PTGVIYPAESLARLGEVVKKVHKRNGHLIYVISDEPYARIAYDGKQVPNIFPLIESSVIV
CCEEEECHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCHHHHHCCEEEE
TSHSKDLALPGERIGYLAANPRMDTVMQFMAGAVFSNRVLGFVNAPALMQRLVTNLQDES
EECCCCCCCCCHHCEEEECCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHCCCCCC
VDIAAYQDKRDLLVRELTALGFKMVIPDGAFYLFPQSPLADDVAFVKLAQKHHILLVPGA
EEEEEECCHHHHHHHHHHHCCEEEEECCCEEEEECCCCCHHHHHHHHHHCCCEEEEEECC
GFGAPGFFRIAYCVDRAVIERSLPAWAGLAQEAGLKAQ
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCC
>Mature Secondary Structure 
AIATKIASHISKSSWIRRMFEEGERLRREFGDESVYDFTLGNPDVEPPQAFQEELLALA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
RNPLPGMHRYMNNAGYPETRAAVAAKLARDSGIDLTAEHVIMTCGAGGALNVVLKTILNP
CCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEECEEEEECCCCCHHHHHHHHHHCC
GEEVIILAPYFVEYKFYIDNHGGVPVPVWTDHQTFQLDIEAIEQAITLKTRAILICSPNN
CCCEEEEEEEEEEEEEEEECCCCCCCEEECCCCEEEEEHHHHHHHHEEEEEEEEEECCCC
PTGVIYPAESLARLGEVVKKVHKRNGHLIYVISDEPYARIAYDGKQVPNIFPLIESSVIV
CCEEEECHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCHHHHHCCEEEE
TSHSKDLALPGERIGYLAANPRMDTVMQFMAGAVFSNRVLGFVNAPALMQRLVTNLQDES
EECCCCCCCCCHHCEEEECCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHCCCCCC
VDIAAYQDKRDLLVRELTALGFKMVIPDGAFYLFPQSPLADDVAFVKLAQKHHILLVPGA
EEEEEECCHHHHHHHHHHHCCEEEEECCCEEEEECCCCCHHHHHHHHHHCCCEEEEEECC
GFGAPGFFRIAYCVDRAVIERSLPAWAGLAQEAGLKAQ
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]