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The map label for this gene is ddc [H]

Identifier: 118579368

GI number: 118579368

Start: 980635

End: 982338

Strand: Direct

Name: ddc [H]

Synonym: Ppro_0931

Alternate gene names: 118579368

Gene position: 980635-982338 (Clockwise)

Preceding gene: 118579367

Following gene: 118579371

Centisome position: 24.47

GC content: 63.97

Gene sequence:

>1704_bases
ATGCCGAAAAAACGTGACGCAGCCCGCGCCAACCTGGAAACCCTGTACCGGATCTTCACCGTACCCGAGGCGCCCGATTC
GACCCTGGGCGCCATCGACCAGGCGATTGCCGACGATGTAATCGGTTTTTTGCAGACCCATATCGTTGCCGTGGAGCACG
ACCTGGAAGAGATCGAGGCCTACTACTCCTCCCCTGTCATCCCGGAAGAGCCGACCTATGTCTCCGAATATACGGAATTC
GTCAAACGGAACCTGGTGGCCCAGTCGGTGCATACCGCCGCCCCCGGCTTTGTGGGCCACATGACCTCGGCGCTCCCCTA
CTTCATGCTTCCCCTGGCGCGGCTGATGACCGCCCTCAACCAGAACCTGGTCAAGGTGGAGACCTCCAAGGCCTTTACCC
CCATGGAACGGCAGGTTCTGGCCATGCTCCACCGCCTGGTCTATCGCCGGCCGGACGACTTCTATCCCCCCTGGATTCAC
AACAGCCAGCATGCCTTGGGCGCTTTCTGTTCCGGCGGCACCATTGCCAACGTTACGGCGCTCTGGGTGGCGCGCAACCG
CCTCTTCGCCCCCAGCAGGACCTTTGGCGGCATTGCCCGGGAAGGGCTGTTCCGCGCCCTGAAACATCACGGCTGCGACG
GGATCGCCGTGCTCGTCTCCGAGCGGGGACACTACTCCTTCGGCAAGGCCACCGACCTGCTGGGCTTCGGCCGGGACAAC
CTGATCAAGGTGAAGACCGACGGCCATAACCGCATCGACCTGAAGCTGCTCAGGGAAGAGTACCGGCGTCTGCGGGACCG
CAACATCCTTCCGCTGGCGCTGGTGGGCATTGCCGGGACCACCGAAACCGGCAACGTGGACCCGCTGGAGGCCATGGCGG
ATTTCGCCCAGGAGATCGGCTGTCATTTTCACGTGGATGCCGCCTGGGGCGGACCGACCCTCTTTTCCGACCGTTACCGC
TCCCTGCTGGCCGGCATAGAGCGGGCCGATTCGGTGACCATCGACGGCCACAAGCAGCTGTATGTGCCCATGGGGGCGGG
GATGGTGGTGTTCAAGGACCCGACTGCCCAGTCGGCCATAGAGCACCACGCCAACTACATCCTGCGCCGCGGTTCCAAGG
ACCTGGGCAGCCACACCCTGGAGGGGTCGCGGCCCGGGATGGCCATGCTGGTTCATGCCGGTTTTTGCATCATCGGTCGC
AAGGGGTACGAGCTGCTCATCGACAGGGGGATCGAGCGGGCGCGGACCTTTGCCGAGATGGTCCGCAGCCATCCCGATTT
CGAGCTGACCAGCGAGCCGGAGCTGAACATCCTTACCTACCGCTTCAGTCCGGCCAAGGTTCAGCAGGCCCTGGCGCGAG
CAACGGATGAACAGCGCCCCTACATCAACGCGCTCCTGGACCAGGTTAACCAGCAGCTGCAGAAGCACCAGCGGGAAGCG
GGCAAGACCTTCGTCTCCCGAACCCGTCTCTGCGTGGGGCCTCGCCAGGAGGAGTTCACCGTGCTGCGGGCCGTGCTGGC
CAACCCGCTGACCACCGATGAGATCATGGAGGCGATTCTGGCCGAACAGTGCGAGATCGCGCGCACGCCTGAGATTCAGG
CGCTGCTCAGGCAGATAGAGCGGCGCTGTGCAGGTGGGGAGCGGGACGAGCCGCTCCAACTCCAGGACTACCCCGGTGAG
TTGGACGAGCTGGACGAGTCGTAG

Upstream 100 bases:

>100_bases
CCAAACTGGAGCGGGAACCGGATTCCCGCGGGACCGGCGCACAGCCATAGAGATTGGCACTGTTCGTTGCCCCAAGCCTG
CGCAAGAAAGTGAATCCATA

Downstream 100 bases:

>100_bases
GGGAAGCGCAGAGGGTGGGTGCCGGCACATACCGAAAGCTAATTTTCAGCTGGGCTGAATTCAACGCTCCCCCCTTTTCA
AAAGGGTGACTTTGCACGGC

Product: pyridoxal-dependent decarboxylase

Products: NA

Alternate protein names: DABA decarboxylase; DABA-DC [H]

Number of amino acids: Translated: 567; Mature: 566

Protein sequence:

>567_residues
MPKKRDAARANLETLYRIFTVPEAPDSTLGAIDQAIADDVIGFLQTHIVAVEHDLEEIEAYYSSPVIPEEPTYVSEYTEF
VKRNLVAQSVHTAAPGFVGHMTSALPYFMLPLARLMTALNQNLVKVETSKAFTPMERQVLAMLHRLVYRRPDDFYPPWIH
NSQHALGAFCSGGTIANVTALWVARNRLFAPSRTFGGIAREGLFRALKHHGCDGIAVLVSERGHYSFGKATDLLGFGRDN
LIKVKTDGHNRIDLKLLREEYRRLRDRNILPLALVGIAGTTETGNVDPLEAMADFAQEIGCHFHVDAAWGGPTLFSDRYR
SLLAGIERADSVTIDGHKQLYVPMGAGMVVFKDPTAQSAIEHHANYILRRGSKDLGSHTLEGSRPGMAMLVHAGFCIIGR
KGYELLIDRGIERARTFAEMVRSHPDFELTSEPELNILTYRFSPAKVQQALARATDEQRPYINALLDQVNQQLQKHQREA
GKTFVSRTRLCVGPRQEEFTVLRAVLANPLTTDEIMEAILAEQCEIARTPEIQALLRQIERRCAGGERDEPLQLQDYPGE
LDELDES

Sequences:

>Translated_567_residues
MPKKRDAARANLETLYRIFTVPEAPDSTLGAIDQAIADDVIGFLQTHIVAVEHDLEEIEAYYSSPVIPEEPTYVSEYTEF
VKRNLVAQSVHTAAPGFVGHMTSALPYFMLPLARLMTALNQNLVKVETSKAFTPMERQVLAMLHRLVYRRPDDFYPPWIH
NSQHALGAFCSGGTIANVTALWVARNRLFAPSRTFGGIAREGLFRALKHHGCDGIAVLVSERGHYSFGKATDLLGFGRDN
LIKVKTDGHNRIDLKLLREEYRRLRDRNILPLALVGIAGTTETGNVDPLEAMADFAQEIGCHFHVDAAWGGPTLFSDRYR
SLLAGIERADSVTIDGHKQLYVPMGAGMVVFKDPTAQSAIEHHANYILRRGSKDLGSHTLEGSRPGMAMLVHAGFCIIGR
KGYELLIDRGIERARTFAEMVRSHPDFELTSEPELNILTYRFSPAKVQQALARATDEQRPYINALLDQVNQQLQKHQREA
GKTFVSRTRLCVGPRQEEFTVLRAVLANPLTTDEIMEAILAEQCEIARTPEIQALLRQIERRCAGGERDEPLQLQDYPGE
LDELDES
>Mature_566_residues
PKKRDAARANLETLYRIFTVPEAPDSTLGAIDQAIADDVIGFLQTHIVAVEHDLEEIEAYYSSPVIPEEPTYVSEYTEFV
KRNLVAQSVHTAAPGFVGHMTSALPYFMLPLARLMTALNQNLVKVETSKAFTPMERQVLAMLHRLVYRRPDDFYPPWIHN
SQHALGAFCSGGTIANVTALWVARNRLFAPSRTFGGIAREGLFRALKHHGCDGIAVLVSERGHYSFGKATDLLGFGRDNL
IKVKTDGHNRIDLKLLREEYRRLRDRNILPLALVGIAGTTETGNVDPLEAMADFAQEIGCHFHVDAAWGGPTLFSDRYRS
LLAGIERADSVTIDGHKQLYVPMGAGMVVFKDPTAQSAIEHHANYILRRGSKDLGSHTLEGSRPGMAMLVHAGFCIIGRK
GYELLIDRGIERARTFAEMVRSHPDFELTSEPELNILTYRFSPAKVQQALARATDEQRPYINALLDQVNQQLQKHQREAG
KTFVSRTRLCVGPRQEEFTVLRAVLANPLTTDEIMEAILAEQCEIARTPEIQALLRQIERRCAGGERDEPLQLQDYPGEL
DELDES

Specific function: Catalyzes The Production Of Gaba. [C]

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

Organism=Homo sapiens, GI197383062, Length=448, Percent_Identity=26.5625, Blast_Score=156, Evalue=5e-38,
Organism=Homo sapiens, GI58331246, Length=448, Percent_Identity=26.1160714285714, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI194294551, Length=447, Percent_Identity=27.2930648769575, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI197276620, Length=504, Percent_Identity=23.6111111111111, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI4503875, Length=504, Percent_Identity=23.6111111111111, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI4503281, Length=412, Percent_Identity=22.3300970873786, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI132814448, Length=412, Percent_Identity=22.3300970873786, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI92110055, Length=513, Percent_Identity=21.4424951267057, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17555682, Length=475, Percent_Identity=25.2631578947368, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71993062, Length=452, Percent_Identity=25.6637168141593, Blast_Score=141, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71993058, Length=397, Percent_Identity=27.2040302267003, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI17136594, Length=369, Percent_Identity=30.3523035230352, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24657193, Length=395, Percent_Identity=25.3164556962025, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24657185, Length=395, Percent_Identity=25.3164556962025, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24657188, Length=395, Percent_Identity=25.3164556962025, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI21356415, Length=495, Percent_Identity=23.4343434343434, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24652373, Length=232, Percent_Identity=28.448275862069, Blast_Score=73, Evalue=6e-13,

Paralogues:

None

Copy number: 3820 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR021115 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.86 [H]

Molecular weight: Translated: 63407; Mature: 63276

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKKRDAARANLETLYRIFTVPEAPDSTLGAIDQAIADDVIGFLQTHIVAVEHDLEEIEA
CCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YYSSPVIPEEPTYVSEYTEFVKRNLVAQSVHTAAPGFVGHMTSALPYFMLPLARLMTALN
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC
QNLVKVETSKAFTPMERQVLAMLHRLVYRRPDDFYPPWIHNSQHALGAFCSGGTIANVTA
CCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHH
LWVARNRLFAPSRTFGGIAREGLFRALKHHGCDGIAVLVSERGHYSFGKATDLLGFGRDN
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHCCCCC
LIKVKTDGHNRIDLKLLREEYRRLRDRNILPLALVGIAGTTETGNVDPLEAMADFAQEIG
EEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCC
CHFHVDAAWGGPTLFSDRYRSLLAGIERADSVTIDGHKQLYVPMGAGMVVFKDPTAQSAI
CEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCEEEEECCCHHHHH
EHHANYILRRGSKDLGSHTLEGSRPGMAMLVHAGFCIIGRKGYELLIDRGIERARTFAEM
HHHHHHHHHCCCHHHCCCCCCCCCCCHHHHEECCEEEECCCCHHHHHHHHHHHHHHHHHH
VRSHPDFELTSEPELNILTYRFSPAKVQQALARATDEQRPYINALLDQVNQQLQKHQREA
HHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
GKTFVSRTRLCVGPRQEEFTVLRAVLANPLTTDEIMEAILAEQCEIARTPEIQALLRQIE
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
RRCAGGERDEPLQLQDYPGELDELDES
HHHCCCCCCCCCCCCCCCCCHHCCCCC
>Mature Secondary Structure 
PKKRDAARANLETLYRIFTVPEAPDSTLGAIDQAIADDVIGFLQTHIVAVEHDLEEIEA
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YYSSPVIPEEPTYVSEYTEFVKRNLVAQSVHTAAPGFVGHMTSALPYFMLPLARLMTALN
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC
QNLVKVETSKAFTPMERQVLAMLHRLVYRRPDDFYPPWIHNSQHALGAFCSGGTIANVTA
CCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHH
LWVARNRLFAPSRTFGGIAREGLFRALKHHGCDGIAVLVSERGHYSFGKATDLLGFGRDN
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHCCCCC
LIKVKTDGHNRIDLKLLREEYRRLRDRNILPLALVGIAGTTETGNVDPLEAMADFAQEIG
EEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCC
CHFHVDAAWGGPTLFSDRYRSLLAGIERADSVTIDGHKQLYVPMGAGMVVFKDPTAQSAI
CEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCEEEEECCCHHHHH
EHHANYILRRGSKDLGSHTLEGSRPGMAMLVHAGFCIIGRKGYELLIDRGIERARTFAEM
HHHHHHHHHCCCHHHCCCCCCCCCCCHHHHEECCEEEECCCCHHHHHHHHHHHHHHHHHH
VRSHPDFELTSEPELNILTYRFSPAKVQQALARATDEQRPYINALLDQVNQQLQKHQREA
HHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
GKTFVSRTRLCVGPRQEEFTVLRAVLANPLTTDEIMEAILAEQCEIARTPEIQALLRQIE
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
RRCAGGERDEPLQLQDYPGELDELDES
HHHCCCCCCCCCCCCCCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9514614 [H]