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The map label for this gene is yiaY [H]

Identifier: 118579324

GI number: 118579324

Start: 933970

End: 935133

Strand: Direct

Name: yiaY [H]

Synonym: Ppro_0887

Alternate gene names: 118579324

Gene position: 933970-935133 (Clockwise)

Preceding gene: 118579322

Following gene: 118579325

Centisome position: 23.3

GC content: 56.44

Gene sequence:

>1164_bases
ATGGCATTAGCAGATCAGACTTTCGGCTTTTTCATCCCCACCGTAACGCTGTTGGGTGTAGGTTGTTCGAAAGAAACCGG
TGAGCAGGCAAAAGCGCTGGGCGCAACGAAACTGCTGATCGTTACAGACGCCGGCCTGAACAAAATGGGCGTGGCCGACA
CGATCAAGGGCTATGTTGAAGCAGTAGGTCTCCAGGCTGTTATTTATGACGGCGCCGAGCCCAACCCGACCGATAAAAAC
GTTGCTGACGGCATTAAAGTCTATCAGGACAACAAGTGCGACGGCCTGATCACCCTTGGTGGCGGCAGCTCCCACGACTG
CGGTAAAGGTATCGGCCTTGTTGTTGCCGGCGGCGGCAACATCCGTGACTACGAAGGCGTTAACAAGTCATCCAAGCGTC
TTCCCCCGTTCCTGGCAATCAACACCACCGCTGGTACCGCCAGCGAAATGACCCGTTTCTGCATCATCACCAACACCGAT
ACCCACGTCAAAATGGCTATCGTTGACTGGCGTGTAACTCCGAACATCGCCATCGACGATCCCCTGCTGATGGTTGGTAT
GCCTCCGAAGCTGACCGCTGCTACCGGTATGGACGCACTGACCCACGCCGTTGAAGCCTATGTTTCCATCATTGCCAACC
CGATCACCGACGCGTGCGCCATCAAGGCCATCGAACTGATCGCCAAGAATCTGAGCGTGGCTGTTGCCAACGGCGAAGAC
CTGGTTGCCCGTGACGCCATGGCATATGCCGAATATCTGGCCGGTATGGCATTCAACAACGCCAGCCTCGGCTATGTTCA
CTCCATGGCTCACCAGTTGGGCGGTTTCTACAACCTGCCCCACGGCGTCTGCAACGCCATCCTGCTGCCCGTCGTCAGCC
AGTTCAACCTGATCGCCTGCCCGCAGCGTTTTGCTGACATCGCCGTTGCTCTCGGCGAAAACATCTGTGGTCTCTCCACC
ATCGAAGCCGGCCAGAAAGCCATCGACAGGATCAAGTCCCTGTCCGCTTCCATCGGCATCCCCGCCAACCTGACCGAGCT
GGGCGTGAAAGAAGCCGACCTGAAGATCATGTCCGAAAACGCCAAGAAAGATGCTTGCCAGCTGACCAACCCGCGTAAAG
CCACGTTGGACGAAGTCATTGCCATCTTCAAGTCTGCTCTGTAA

Upstream 100 bases:

>100_bases
AGCTTTGATTTGTTTGTGACGAAAAGAGGCTTGCCAGAATTGTCTGGCAAATAAGATCAGGGTGGCGACACTCTGTACAC
CACACAAGGAGGAAGTACAC

Downstream 100 bases:

>100_bases
TACTCATTTTTCTCTCTGTTAAGGAGGGAACGGCTGGAAGTGATGGGCAGTGTCATAACGCACTGCCCATCACTGTAAAA
GGATTCCTGCATAACAAAAA

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MALADQTFGFFIPTVTLLGVGCSKETGEQAKALGATKLLIVTDAGLNKMGVADTIKGYVEAVGLQAVIYDGAEPNPTDKN
VADGIKVYQDNKCDGLITLGGGSSHDCGKGIGLVVAGGGNIRDYEGVNKSSKRLPPFLAINTTAGTASEMTRFCIITNTD
THVKMAIVDWRVTPNIAIDDPLLMVGMPPKLTAATGMDALTHAVEAYVSIIANPITDACAIKAIELIAKNLSVAVANGED
LVARDAMAYAEYLAGMAFNNASLGYVHSMAHQLGGFYNLPHGVCNAILLPVVSQFNLIACPQRFADIAVALGENICGLST
IEAGQKAIDRIKSLSASIGIPANLTELGVKEADLKIMSENAKKDACQLTNPRKATLDEVIAIFKSAL

Sequences:

>Translated_387_residues
MALADQTFGFFIPTVTLLGVGCSKETGEQAKALGATKLLIVTDAGLNKMGVADTIKGYVEAVGLQAVIYDGAEPNPTDKN
VADGIKVYQDNKCDGLITLGGGSSHDCGKGIGLVVAGGGNIRDYEGVNKSSKRLPPFLAINTTAGTASEMTRFCIITNTD
THVKMAIVDWRVTPNIAIDDPLLMVGMPPKLTAATGMDALTHAVEAYVSIIANPITDACAIKAIELIAKNLSVAVANGED
LVARDAMAYAEYLAGMAFNNASLGYVHSMAHQLGGFYNLPHGVCNAILLPVVSQFNLIACPQRFADIAVALGENICGLST
IEAGQKAIDRIKSLSASIGIPANLTELGVKEADLKIMSENAKKDACQLTNPRKATLDEVIAIFKSAL
>Mature_386_residues
ALADQTFGFFIPTVTLLGVGCSKETGEQAKALGATKLLIVTDAGLNKMGVADTIKGYVEAVGLQAVIYDGAEPNPTDKNV
ADGIKVYQDNKCDGLITLGGGSSHDCGKGIGLVVAGGGNIRDYEGVNKSSKRLPPFLAINTTAGTASEMTRFCIITNTDT
HVKMAIVDWRVTPNIAIDDPLLMVGMPPKLTAATGMDALTHAVEAYVSIIANPITDACAIKAIELIAKNLSVAVANGEDL
VARDAMAYAEYLAGMAFNNASLGYVHSMAHQLGGFYNLPHGVCNAILLPVVSQFNLIACPQRFADIAVALGENICGLSTI
EAGQKAIDRIKSLSASIGIPANLTELGVKEADLKIMSENAKKDACQLTNPRKATLDEVIAIFKSAL

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=408, Percent_Identity=26.4705882352941, Blast_Score=134, Evalue=2e-31,
Organism=Escherichia coli, GI48994951, Length=378, Percent_Identity=56.6137566137566, Blast_Score=444, Evalue=1e-126,
Organism=Escherichia coli, GI1789163, Length=373, Percent_Identity=41.8230563002681, Blast_Score=278, Evalue=5e-76,
Organism=Escherichia coli, GI87082107, Length=378, Percent_Identity=35.4497354497354, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1787493, Length=381, Percent_Identity=33.5958005249344, Blast_Score=197, Evalue=9e-52,
Organism=Escherichia coli, GI1789386, Length=388, Percent_Identity=24.2268041237113, Blast_Score=85, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17537053, Length=412, Percent_Identity=23.7864077669903, Blast_Score=122, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6321181, Length=381, Percent_Identity=50.9186351706037, Blast_Score=388, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24657991, Length=409, Percent_Identity=26.6503667481663, Blast_Score=139, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 40484; Mature: 40353

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALADQTFGFFIPTVTLLGVGCSKETGEQAKALGATKLLIVTDAGLNKMGVADTIKGYVE
CCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHH
AVGLQAVIYDGAEPNPTDKNVADGIKVYQDNKCDGLITLGGGSSHDCGKGIGLVVAGGGN
HHCCEEEEECCCCCCCCCCCHHCCCEEEECCCCCEEEEECCCCCCCCCCCCEEEEECCCC
IRDYEGVNKSSKRLPPFLAINTTAGTASEMTRFCIITNTDTHVKMAIVDWRVTPNIAIDD
CCCCCCCCCCHHCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEEEEECCCCEECC
PLLMVGMPPKLTAATGMDALTHAVEAYVSIIANPITDACAIKAIELIAKNLSVAVANGED
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCH
LVARDAMAYAEYLAGMAFNNASLGYVHSMAHQLGGFYNLPHGVCNAILLPVVSQFNLIAC
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEC
PQRFADIAVALGENICGLSTIEAGQKAIDRIKSLSASIGIPANLTELGVKEADLKIMSEN
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHEECCC
AKKDACQLTNPRKATLDEVIAIFKSAL
CCHHHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALADQTFGFFIPTVTLLGVGCSKETGEQAKALGATKLLIVTDAGLNKMGVADTIKGYVE
CCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHH
AVGLQAVIYDGAEPNPTDKNVADGIKVYQDNKCDGLITLGGGSSHDCGKGIGLVVAGGGN
HHCCEEEEECCCCCCCCCCCHHCCCEEEECCCCCEEEEECCCCCCCCCCCCEEEEECCCC
IRDYEGVNKSSKRLPPFLAINTTAGTASEMTRFCIITNTDTHVKMAIVDWRVTPNIAIDD
CCCCCCCCCCHHCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEEEEECCCCEECC
PLLMVGMPPKLTAATGMDALTHAVEAYVSIIANPITDACAIKAIELIAKNLSVAVANGED
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCH
LVARDAMAYAEYLAGMAFNNASLGYVHSMAHQLGGFYNLPHGVCNAILLPVVSQFNLIAC
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEC
PQRFADIAVALGENICGLSTIEAGQKAIDRIKSLSASIGIPANLTELGVKEADLKIMSEN
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHEECCC
AKKDACQLTNPRKATLDEVIAIFKSAL
CCHHHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]