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The map label for this gene is stc [H]

Identifier: 118579322

GI number: 118579322

Start: 930226

End: 932211

Strand: Direct

Name: stc [H]

Synonym: Ppro_0885

Alternate gene names: 118579322

Gene position: 930226-932211 (Clockwise)

Preceding gene: 118579317

Following gene: 118579324

Centisome position: 23.21

GC content: 54.83

Gene sequence:

>1986_bases
ATGCAAGATAATCATACGATCCCGCAGACCCTAACGGTTCTTGAGCAGACATGGAACCGCTATGTCCAGAATGAAGTGAT
TGAGATTCATCGAATCCGGCCGGAGGTGGCAAACTCCTGGCAACGCTGCCGAAACTACAAGGTCAATCCCTATGACATTG
GTGACCAGGCGGTAAATCAGCTGGAACTCAGGGAACGTCTCCACCGTAATCACCATCTGGTAAAGATCGCGCGTTCTGCC
ATGGAAAACCTGTATACCTTTGTTCGGGGGTCTGGTTTTGAAATCGTCCTGTCGGACCAGCATGCCTACCTGCTGGAGGT
TGTGGGGGATCGTGACATAATCAGCAAGGGGACCAAGGTTCAGCTCTGTCCCGGCGGCAACTGGCATGAGTCGTCCAAGG
GAACCAACGCCATCGGGACCGCTCTCATGGAGAAACAGCCGGTTCAGATCCTGGCCTGGGAACACTTCTGTCGGCCGAAT
CATTTTCTGACCTGCTCCGCTGCCCCCATTTTTGATCCTGAAGGGGAGATTGTGGGGGTTCTCAATATCTCCGGAGATTA
CCGTTATGCCAATGCCCATACCCTCGGCATGGTTGTGGCAGCGGTAAATGCCATCGAAAAACAGCTTTGTCTTCATAAGG
TCACCAGTAAACTCTACATCTCCTACAAATACTCCCAGACCCTTTTGGAATCCATTTCGGACGGTATCGTCTCCGTGAAC
AACAGCGGCATCATTGCCGAGATGAACTCCAGCGGTGGCAAAATATTCGGCATCAATCACCAGGCGGCCAAGGGCAAGCA
TATCAACACCGTCATGCGCCAGCAGGCGCCAATTCTGTCGCTGCTTGCCACCGGTGAGGGGTATCGGGATAGGGAAATTC
TGCTGGAGAACCAGGGGAAGAAGGTGTTTAGTTCTGCTACCCTGCTGCTGGATGATTCCGGCAACACCATCGGTGCCGTT
GCCGTCCTGCGCCAGGCGCGGGACGCGCTGAAGTCCCGCCGCGCCCAGCATTCCTCGTTGCCCCGCTACTCCTTTGACGA
CATTATCGGAGAGAGCCCCGCCATCAGCGAGGCCAAGGAATGGGCACGGATCGCGGCAAACAGTGGTTCGACCATTCTGC
TCAGCGGTGAGAGCGGTACCGGCAAGGAGTTGTTTGCCCAGTCAATTCACAATGTCAGCTCTTTCAGGAACGGCCCTTTT
ATTGCCATCAACTGCGCCGCTATCCCGGAAGCCCTTGTTGAAAGTGAGCTGTTCGGCTATGCGGAGGGAACTTTCACCGG
TGCCAAAAAAGGCGGTAGCCCGGGTAAATTCGAGAGTGCCGACCGTGGTACGCTCTTTCTCGACGAGATAGGCGATATGC
CGCTTACTGTTCAGGCCAAGGTGTTGAGGGTTATCCAGGAAAAGAAGATCTCCCGCGTTGGTTCCAGCGAAGAGCGCCAG
GTGGAGATTCGCATCATCGCCTCGACCCATAAGAATCTGCGGACAGAGGTGCTAAACGGTAATTTTCGGGAAGACCTCTT
CTACAGGCTCAATGTCCTGGTCGTCCAGGTTCCGCCTTTGCGTGACAGGGGCGGGGATATCCCCTTGGTCGCCTGCCATC
TGGTGGAGAAGATCTCCGCAAGGATGGGCAAACAGCGGATCGTTGGGGAAGATGCTTTCTGGGGAAAGCTTGCCTCTCAT
AACTGGCCCGGTAATGTTCGTGAACTGGAAAATGCCATCGAGCAGGCTGTCGTCAGGTCGGATGACTCCGGGGTCCTGTT
GGCTCGTCATCTGACGTTTGATGTCGTTGAGTCCGTCGCACCCACGGGGGGGAGGGCAGAGATCGTTTCTCTCACTGAAA
TGGAAAAGCAGGCCATAACTGCTGCGCTTCATCTCTATGATGGCAATATCCAGAAGGCTGCTTCGAAACTCGGTATCGGG
CGTAACACCCTGTACCGCAAAATCAGGGAGTACGGCATCGCACATGCCGGTTCCCAAGTCCATTGA

Upstream 100 bases:

>100_bases
TTATGAAGAGAAGCTGCAACGGAAGAGGTTGGCTGTGTCTGGTAGTGTCGCGTTTCGTTGTATGGCTGCAAAGGCCTCTG
TGCCACCTGGTGAATGAACT

Downstream 100 bases:

>100_bases
TCCTGGTCCTGATCTAAAAGGGGGAGTCTTTCGGCTCCCCCTTTTAGATCAGATACATCACACAACTCTTGTCCTCCGCA
TAATCTCACCTCTGTTTTTC

Product: Fis family GAF modulated sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MQDNHTIPQTLTVLEQTWNRYVQNEVIEIHRIRPEVANSWQRCRNYKVNPYDIGDQAVNQLELRERLHRNHHLVKIARSA
MENLYTFVRGSGFEIVLSDQHAYLLEVVGDRDIISKGTKVQLCPGGNWHESSKGTNAIGTALMEKQPVQILAWEHFCRPN
HFLTCSAAPIFDPEGEIVGVLNISGDYRYANAHTLGMVVAAVNAIEKQLCLHKVTSKLYISYKYSQTLLESISDGIVSVN
NSGIIAEMNSSGGKIFGINHQAAKGKHINTVMRQQAPILSLLATGEGYRDREILLENQGKKVFSSATLLLDDSGNTIGAV
AVLRQARDALKSRRAQHSSLPRYSFDDIIGESPAISEAKEWARIAANSGSTILLSGESGTGKELFAQSIHNVSSFRNGPF
IAINCAAIPEALVESELFGYAEGTFTGAKKGGSPGKFESADRGTLFLDEIGDMPLTVQAKVLRVIQEKKISRVGSSEERQ
VEIRIIASTHKNLRTEVLNGNFREDLFYRLNVLVVQVPPLRDRGGDIPLVACHLVEKISARMGKQRIVGEDAFWGKLASH
NWPGNVRELENAIEQAVVRSDDSGVLLARHLTFDVVESVAPTGGRAEIVSLTEMEKQAITAALHLYDGNIQKAASKLGIG
RNTLYRKIREYGIAHAGSQVH

Sequences:

>Translated_661_residues
MQDNHTIPQTLTVLEQTWNRYVQNEVIEIHRIRPEVANSWQRCRNYKVNPYDIGDQAVNQLELRERLHRNHHLVKIARSA
MENLYTFVRGSGFEIVLSDQHAYLLEVVGDRDIISKGTKVQLCPGGNWHESSKGTNAIGTALMEKQPVQILAWEHFCRPN
HFLTCSAAPIFDPEGEIVGVLNISGDYRYANAHTLGMVVAAVNAIEKQLCLHKVTSKLYISYKYSQTLLESISDGIVSVN
NSGIIAEMNSSGGKIFGINHQAAKGKHINTVMRQQAPILSLLATGEGYRDREILLENQGKKVFSSATLLLDDSGNTIGAV
AVLRQARDALKSRRAQHSSLPRYSFDDIIGESPAISEAKEWARIAANSGSTILLSGESGTGKELFAQSIHNVSSFRNGPF
IAINCAAIPEALVESELFGYAEGTFTGAKKGGSPGKFESADRGTLFLDEIGDMPLTVQAKVLRVIQEKKISRVGSSEERQ
VEIRIIASTHKNLRTEVLNGNFREDLFYRLNVLVVQVPPLRDRGGDIPLVACHLVEKISARMGKQRIVGEDAFWGKLASH
NWPGNVRELENAIEQAVVRSDDSGVLLARHLTFDVVESVAPTGGRAEIVSLTEMEKQAITAALHLYDGNIQKAASKLGIG
RNTLYRKIREYGIAHAGSQVH
>Mature_661_residues
MQDNHTIPQTLTVLEQTWNRYVQNEVIEIHRIRPEVANSWQRCRNYKVNPYDIGDQAVNQLELRERLHRNHHLVKIARSA
MENLYTFVRGSGFEIVLSDQHAYLLEVVGDRDIISKGTKVQLCPGGNWHESSKGTNAIGTALMEKQPVQILAWEHFCRPN
HFLTCSAAPIFDPEGEIVGVLNISGDYRYANAHTLGMVVAAVNAIEKQLCLHKVTSKLYISYKYSQTLLESISDGIVSVN
NSGIIAEMNSSGGKIFGINHQAAKGKHINTVMRQQAPILSLLATGEGYRDREILLENQGKKVFSSATLLLDDSGNTIGAV
AVLRQARDALKSRRAQHSSLPRYSFDDIIGESPAISEAKEWARIAANSGSTILLSGESGTGKELFAQSIHNVSSFRNGPF
IAINCAAIPEALVESELFGYAEGTFTGAKKGGSPGKFESADRGTLFLDEIGDMPLTVQAKVLRVIQEKKISRVGSSEERQ
VEIRIIASTHKNLRTEVLNGNFREDLFYRLNVLVVQVPPLRDRGGDIPLVACHLVEKISARMGKQRIVGEDAFWGKLASH
NWPGNVRELENAIEQAVVRSDDSGVLLARHLTFDVVESVAPTGGRAEIVSLTEMEKQAITAALHLYDGNIQKAASKLGIG
RNTLYRKIREYGIAHAGSQVH

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=342, Percent_Identity=43.2748538011696, Blast_Score=256, Evalue=3e-69,
Organism=Escherichia coli, GI1790437, Length=302, Percent_Identity=44.7019867549669, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI1789233, Length=324, Percent_Identity=45.3703703703704, Blast_Score=249, Evalue=6e-67,
Organism=Escherichia coli, GI87082117, Length=323, Percent_Identity=43.6532507739938, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1789087, Length=313, Percent_Identity=43.1309904153355, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI1790299, Length=332, Percent_Identity=42.1686746987952, Blast_Score=237, Evalue=2e-63,
Organism=Escherichia coli, GI1788905, Length=303, Percent_Identity=42.9042904290429, Blast_Score=234, Evalue=9e-63,
Organism=Escherichia coli, GI87082152, Length=317, Percent_Identity=42.2712933753943, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1786524, Length=361, Percent_Identity=38.5041551246537, Blast_Score=233, Evalue=3e-62,
Organism=Escherichia coli, GI87081858, Length=630, Percent_Identity=26.5079365079365, Blast_Score=228, Evalue=1e-60,
Organism=Escherichia coli, GI1787583, Length=356, Percent_Identity=35.6741573033708, Blast_Score=195, Evalue=8e-51,
Organism=Escherichia coli, GI87081872, Length=308, Percent_Identity=38.6363636363636, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI1789828, Length=243, Percent_Identity=34.5679012345679, Blast_Score=123, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 72910; Mature: 72910

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDNHTIPQTLTVLEQTWNRYVQNEVIEIHRIRPEVANSWQRCRNYKVNPYDIGDQAVNQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHH
LELRERLHRNHHLVKIARSAMENLYTFVRGSGFEIVLSDQHAYLLEVVGDRDIISKGTKV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEECCCHHHCCCCEE
QLCPGGNWHESSKGTNAIGTALMEKQPVQILAWEHFCRPNHFLTCSAAPIFDPEGEIVGV
EECCCCCCCCCCCCCHHHHHHHHCCCCCEEEEHHHHCCCCCEEEECCCCCCCCCCCEEEE
LNISGDYRYANAHTLGMVVAAVNAIEKQLCLHKVTSKLYISYKYSQTLLESISDGIVSVN
EEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHCCCEEEEC
NSGIIAEMNSSGGKIFGINHQAAKGKHINTVMRQQAPILSLLATGEGYRDREILLENQGK
CCCEEEEECCCCCEEEEECCCCCCCCHHHHHHHHCCCHHHHHHCCCCCCCCCCEEECCCC
KVFSSATLLLDDSGNTIGAVAVLRQARDALKSRRAQHSSLPRYSFDDIIGESPAISEAKE
EEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHH
WARIAANSGSTILLSGESGTGKELFAQSIHNVSSFRNGPFIAINCAAIPEALVESELFGY
HHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHCC
AEGTFTGAKKGGSPGKFESADRGTLFLDEIGDMPLTVQAKVLRVIQEKKISRVGSSEERQ
CCCCCCCCCCCCCCCCCCCCCCCEEEHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCCCCE
VEIRIIASTHKNLRTEVLNGNFREDLFYRLNVLVVQVPPLRDRGGDIPLVACHLVEKISA
EEEEEEECCCHHHHHHHHCCCHHHHHHEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHH
RMGKQRIVGEDAFWGKLASHNWPGNVRELENAIEQAVVRSDDSGVLLARHLTFDVVESVA
HHCCHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHC
PTGGRAEIVSLTEMEKQAITAALHLYDGNIQKAASKLGIGRNTLYRKIREYGIAHAGSQV
CCCCCEEEEEHHHHHHHHHHHHHEEECCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCC
H
C
>Mature Secondary Structure
MQDNHTIPQTLTVLEQTWNRYVQNEVIEIHRIRPEVANSWQRCRNYKVNPYDIGDQAVNQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHH
LELRERLHRNHHLVKIARSAMENLYTFVRGSGFEIVLSDQHAYLLEVVGDRDIISKGTKV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEECCCHHHCCCCEE
QLCPGGNWHESSKGTNAIGTALMEKQPVQILAWEHFCRPNHFLTCSAAPIFDPEGEIVGV
EECCCCCCCCCCCCCHHHHHHHHCCCCCEEEEHHHHCCCCCEEEECCCCCCCCCCCEEEE
LNISGDYRYANAHTLGMVVAAVNAIEKQLCLHKVTSKLYISYKYSQTLLESISDGIVSVN
EEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHCCCEEEEC
NSGIIAEMNSSGGKIFGINHQAAKGKHINTVMRQQAPILSLLATGEGYRDREILLENQGK
CCCEEEEECCCCCEEEEECCCCCCCCHHHHHHHHCCCHHHHHHCCCCCCCCCCEEECCCC
KVFSSATLLLDDSGNTIGAVAVLRQARDALKSRRAQHSSLPRYSFDDIIGESPAISEAKE
EEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHH
WARIAANSGSTILLSGESGTGKELFAQSIHNVSSFRNGPFIAINCAAIPEALVESELFGY
HHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHCC
AEGTFTGAKKGGSPGKFESADRGTLFLDEIGDMPLTVQAKVLRVIQEKKISRVGSSEERQ
CCCCCCCCCCCCCCCCCCCCCCCEEEHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCCCCE
VEIRIIASTHKNLRTEVLNGNFREDLFYRLNVLVVQVPPLRDRGGDIPLVACHLVEKISA
EEEEEEECCCHHHHHHHHCCCHHHHHHEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHH
RMGKQRIVGEDAFWGKLASHNWPGNVRELENAIEQAVVRSDDSGVLLARHLTFDVVESVA
HHCCHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHC
PTGGRAEIVSLTEMEKQAITAALHLYDGNIQKAASKLGIGRNTLYRKIREYGIAHAGSQV
CCCCCEEEEEHHHHHHHHHHHHHEEECCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCC
H
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA