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The map label for this gene is aroF [H]

Identifier: 118579266

GI number: 118579266

Start: 876602

End: 877714

Strand: Direct

Name: aroF [H]

Synonym: Ppro_0829

Alternate gene names: 118579266

Gene position: 876602-877714 (Clockwise)

Preceding gene: 118579265

Following gene: 118579269

Centisome position: 21.87

GC content: 61.73

Gene sequence:

>1113_bases
GTGAACATCAAAAAACTAATCATACATGATCGGAAGCCGGTCATCGGTCCGGACGACCTGAGACGCAGATTTCCTCTTTC
AGGAGAAGACGTCGCGCGTGTGGCCCATTTCCGGAAGCAGGTGGCCGACATCCTGAACGGCGTCGACGGGCGGCTGCTGG
CGGTGGTCGGCCCCTGCTCGATTCATGACACCAGGGCGGCTCTTGACTATGCTGAGCGCCTGGCCGGCCTGGCAGGGGAA
CTGGAGGACCGGCTGCTGCCGGTGATGCGGGTGTATCTGGAAAAACCGCGTACCGCTACGGGCTGGAAAGGGCTGCTCAA
CGACCCGGACCTGGACGGATCGTGCCGGATATCCAAGGGGCTCGTGATTGCCCGCGACCTGCTCCGTTCCATTACCGGTC
TGGGCCTTCCCGTGGCCTGCGAGATACTCAGCCCGTTTACCCCCCTCTATCTGGGTGATCTGATCAGCTGGGGGGCGATC
GGCGCACGCACGACCGAATCGCAGATTCACCGGGAAATGGCGAGCGGGCTTCCCTTTCCGGTCGGCTTCAAGAACGGCAC
CGACGGCAACCTGCGGATCGCCGTTGACGCCGTCCGTGCCGCCCGGTACCCGCACCGCTTCCTGAGTGTCGATAAGAACG
GGCGCTACACCAGCGTCATGGCCGGCGGCAACGCCGATGCTCACGTGATTCTTCGCGGCGGCAACGGCCGCTCCAATTAT
TTTCCCGAGGACATTCGCAAGGTAGAGGAGATGCTGGACAAGGCCGGTCTCACTCAGGCAATCGCGGTAGATTGCAGTCA
TGCAAACTCCGGCGGCGACCACCAGCGCCAGCAGGAGGGGCTGGTCACTGTCTGCCGGCAGCTCGCCGACGGCAACAGTT
CGATTCGCTGCATAATGCTTGAGAGTTTTCTGGAAGCCGGCAATCAGCCGATTCCCACGGACCTGTCGCAGCTCAGATAC
GGTGTTTCTGTTACCGACAAGTGCATCGACTGGACCACCACCGAGTACCTTCTGCGCTACGTCCATCGGACAATGGCCTG
TCGAGGTGTCGGCATGGCACAGACCGATCTCGAACGGGCGCACAACGGCGATATCAGATGCGCGGCCATGTAG

Upstream 100 bases:

>100_bases
ACCTCGCCGTTTTCAAGGCATGGGTCGGAACATGGGTCGTGAAGCGGTGGCCTGACGTTACCAAGGACGAGTTGAACGGC
ATCAGGGTGAAATACTGATT

Downstream 100 bases:

>100_bases
CCGATTGCTGTCGCTTTGATCGATGGCGCCGCTCTTGAGGCAATATCCCGTCAGCCTGAATCTCCGTGTATGTTTCCCCC
CGAGAAGACGTCTTGGTGGT

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MNIKKLIIHDRKPVIGPDDLRRRFPLSGEDVARVAHFRKQVADILNGVDGRLLAVVGPCSIHDTRAALDYAERLAGLAGE
LEDRLLPVMRVYLEKPRTATGWKGLLNDPDLDGSCRISKGLVIARDLLRSITGLGLPVACEILSPFTPLYLGDLISWGAI
GARTTESQIHREMASGLPFPVGFKNGTDGNLRIAVDAVRAARYPHRFLSVDKNGRYTSVMAGGNADAHVILRGGNGRSNY
FPEDIRKVEEMLDKAGLTQAIAVDCSHANSGGDHQRQQEGLVTVCRQLADGNSSIRCIMLESFLEAGNQPIPTDLSQLRY
GVSVTDKCIDWTTTEYLLRYVHRTMACRGVGMAQTDLERAHNGDIRCAAM

Sequences:

>Translated_370_residues
MNIKKLIIHDRKPVIGPDDLRRRFPLSGEDVARVAHFRKQVADILNGVDGRLLAVVGPCSIHDTRAALDYAERLAGLAGE
LEDRLLPVMRVYLEKPRTATGWKGLLNDPDLDGSCRISKGLVIARDLLRSITGLGLPVACEILSPFTPLYLGDLISWGAI
GARTTESQIHREMASGLPFPVGFKNGTDGNLRIAVDAVRAARYPHRFLSVDKNGRYTSVMAGGNADAHVILRGGNGRSNY
FPEDIRKVEEMLDKAGLTQAIAVDCSHANSGGDHQRQQEGLVTVCRQLADGNSSIRCIMLESFLEAGNQPIPTDLSQLRY
GVSVTDKCIDWTTTEYLLRYVHRTMACRGVGMAQTDLERAHNGDIRCAAM
>Mature_370_residues
MNIKKLIIHDRKPVIGPDDLRRRFPLSGEDVARVAHFRKQVADILNGVDGRLLAVVGPCSIHDTRAALDYAERLAGLAGE
LEDRLLPVMRVYLEKPRTATGWKGLLNDPDLDGSCRISKGLVIARDLLRSITGLGLPVACEILSPFTPLYLGDLISWGAI
GARTTESQIHREMASGLPFPVGFKNGTDGNLRIAVDAVRAARYPHRFLSVDKNGRYTSVMAGGNADAHVILRGGNGRSNY
FPEDIRKVEEMLDKAGLTQAIAVDCSHANSGGDHQRQQEGLVTVCRQLADGNSSIRCIMLESFLEAGNQPIPTDLSQLRY
GVSVTDKCIDWTTTEYLLRYVHRTMACRGVGMAQTDLERAHNGDIRCAAM

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=338, Percent_Identity=52.0710059171598, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI1786969, Length=343, Percent_Identity=51.0204081632653, Blast_Score=330, Evalue=7e-92,
Organism=Escherichia coli, GI1787996, Length=327, Percent_Identity=50.1529051987768, Blast_Score=321, Evalue=4e-89,
Organism=Saccharomyces cerevisiae, GI6320240, Length=335, Percent_Identity=48.0597014925373, Blast_Score=317, Evalue=2e-87,
Organism=Saccharomyces cerevisiae, GI6319726, Length=328, Percent_Identity=47.5609756097561, Blast_Score=306, Evalue=5e-84,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 40527; Mature: 40527

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKKLIIHDRKPVIGPDDLRRRFPLSGEDVARVAHFRKQVADILNGVDGRLLAVVGPCS
CCCCEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
IHDTRAALDYAERLAGLAGELEDRLLPVMRVYLEKPRTATGWKGLLNDPDLDGSCRISKG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHCC
LVIARDLLRSITGLGLPVACEILSPFTPLYLGDLISWGAIGARTTESQIHREMASGLPFP
HHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCC
VGFKNGTDGNLRIAVDAVRAARYPHRFLSVDKNGRYTSVMAGGNADAHVILRGGNGRSNY
CCCCCCCCCCEEEEEEHHHHHHCCHHHEEECCCCCEEEEEECCCCCEEEEEECCCCCCCC
FPEDIRKVEEMLDKAGLTQAIAVDCSHANSGGDHQRQQEGLVTVCRQLADGNSSIRCIML
CHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEE
ESFLEAGNQPIPTDLSQLRYGVSVTDKCIDWTTTEYLLRYVHRTMACRGVGMAQTDLERA
HHHHHCCCCCCCCCHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
HNGDIRCAAM
CCCCEEEEEC
>Mature Secondary Structure
MNIKKLIIHDRKPVIGPDDLRRRFPLSGEDVARVAHFRKQVADILNGVDGRLLAVVGPCS
CCCCEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
IHDTRAALDYAERLAGLAGELEDRLLPVMRVYLEKPRTATGWKGLLNDPDLDGSCRISKG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHCC
LVIARDLLRSITGLGLPVACEILSPFTPLYLGDLISWGAIGARTTESQIHREMASGLPFP
HHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCC
VGFKNGTDGNLRIAVDAVRAARYPHRFLSVDKNGRYTSVMAGGNADAHVILRGGNGRSNY
CCCCCCCCCCEEEEEEHHHHHHCCHHHEEECCCCCEEEEEECCCCCEEEEEECCCCCCCC
FPEDIRKVEEMLDKAGLTQAIAVDCSHANSGGDHQRQQEGLVTVCRQLADGNSSIRCIML
CHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEE
ESFLEAGNQPIPTDLSQLRYGVSVTDKCIDWTTTEYLLRYVHRTMACRGVGMAQTDLERA
HHHHHCCCCCCCCCHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
HNGDIRCAAM
CCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]