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The map label for this gene is kefB [H]

Identifier: 118579222

GI number: 118579222

Start: 832320

End: 834317

Strand: Reverse

Name: kefB [H]

Synonym: Ppro_0784

Alternate gene names: 118579222

Gene position: 834317-832320 (Counterclockwise)

Preceding gene: 118579223

Following gene: 118579221

Centisome position: 20.82

GC content: 62.96

Gene sequence:

>1998_bases
GTGCCTTACGAGACCCTGCAAGACATCGAGATTCTCTTCGGCCTGGCACTGATAACGGTGATCCTCTTCCGTCGCCTGAT
GTTCCCCTCCATCGTCGGCTTCATGGCCACCGGCATCCTGGCCGGCCCCCACGCCCTGGGATTCATCAAAAACAGCCACC
AGGTGGAACAGATGGCCGAAATCGGCGTGGTGCTGCTCCTGTTCACCATCGGCATCGAGCTTTCCCTGAAGGAACTGATG
CGCATCAGGCATCTGGTGCTTTTGGGCGGCGGGCTGCAGGTTCTGGTCACCATCCTGGTAGTGGCAGGCGTGGCCATGCT
TGGCGGCTTCCCGGCCAACCAGTCGGTCTTCTTCGGGTTTCTGGTGGCCCTCTCCAGCACCGCCATCCTGATGAAGCTCT
TGATCGACAGCGGCCAGGCGGACACGCCCCACGGCAAAATGGCCATGGGCATCCTGATCTTCCAGGACCTGTGCATCGTA
CCGCTGATGCTGCTGACCCCGCTCCTGGCGGGCGGAGGCGACGGAGCACGGGAGATCGTGCTGATCGGCGCCAAGGCTGC
AGCCGTCGTGGTCATGGCCCATTACGGCGCCCGTTTCCTGGTGCCGTGGATATTCAAACAGGTGGTAAGGACCAGAAGCA
GGGAACTGTTCATCCTGACCATCATCTTCATCGGACTGGGCACGGCCTGGCTGACCGCCCTGGCCGGCCTCTCCCTGGCG
CTGGGGGCGTTCATCGCCGGCCTGGCCATCTCGGAATCGGAATACAGCCACCAGGCGTTGGGCGACATCATCCCCTTCCG
CGAGGCCTTCATGAGCCTCTTCTTTATCTCGGTGGGCATGCTGCTTGACCCTGCCATCCTGCTGAAGCATCCACTGCTGA
TCGCCTCGCTGGTGGCAGCCATCCTGCTTATCAAGACCCTAGTCACCAGCGGGGCTGGCATGGCCCTGGGAGTTTCCACC
CGCATCACCGTTATCACGGCGCTCTCCCTGGCCCAGATCGGCGAGTTCTCCTTCGTGCTCTCCCAGAGCGGCGTCAATCT
GGGAATCCTCACCCCGGACATGTACCAGATATTCCTAGCCGCCTCCATCGCCACCATGGGACTGACACCGGCCTGCCTCG
GATTCGCCCCAGCTGTGGCGGAGCGCATCAGCACCCTGCTCCCCCGCCGCTGGAGCCGTGGCCGGGGCGTCCTTGCCAGC
CACGACCGACCGGTAGCCATGAGCGATCACGTCATCATCGTCGGCTACGGCGTCAACGGCAGAAACCTTTCCCGGGTGCT
GAAGAGCCAGAAGATCCAGCACCTGGTCATTGAGACAAACCCTTTCACGGTCAGGAGCGAGGCCAGGAAGGGACACAAGA
TCCACTTCGGTGACGCATCAAAACCAGAGGTGCTTGAGCATGCCCATGTGGACAGGGCCCGCGTCCTGGTGGTGGCTATC
TCCGATGCCGCGGCCAGCAGGAGGGTCGCCGGTATGGCCCGGCAGATGAACCCGGCGCTGCACATCATCGTCAGGACCCG
CTATGTCCTGGAGGTAGAACCGCTGTTCAAGCTGGGGGTCAACGAGGTCGTGCCGGAAGAGTTCGAGACATCGGTGGAAA
TTTTTTCCCGGGTACTGAGGAACTATCTCGTCCCCCAACATGACGTCGACCGCTGCATCGCCGAGGTGCGCAGCGACGGC
TACGACATGCTGCGTTCCTTAAGCAGACGCCACAGCCACGCCATGGGCATCAGCGGCTATCTCTCCGGCGCCGAGATAGG
AACCTTCCGCGTGCGGGAGGGGTCGCAACTGGAGGCCCGCAGCCTGCGCGAGGGGACCATCAGGAACATGTCCGGGGCAA
CGGTGCTGGTCATCAAGCGGGGTGAGGAGGTCGTGCCCAACCCCGATCCGGTCTGGGAACTGCGCAGGGATGACCTGGTG
CTGCTTTTAGGCAGTGCGGAGCAACTGGCGGCGGCGGGCCGACTGTTCGAGCCGACTCCGCACCTGCGGCAGGCCTAG

Upstream 100 bases:

>100_bases
GCGTCCCACAAGGACGCCCCTTTCACGGCACAATCCATGATGCGACGCGGAGCAGTCGCCTGATTATTGTCCCAACACGG
TGACAGGAGCACACTCTTTC

Downstream 100 bases:

>100_bases
ACGGACAGGCTGCCCCCAGACGTGGGTGAGCGACATCGCCAACAACGCGCATGCCAGGCGACCGGGAGGCGTCTTCATGG
ACCGAACACTACTAAATACG

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: K(+)/H(+) antiporter; NEM-activatable K(+)/H(+) antiporter [H]

Number of amino acids: Translated: 665; Mature: 664

Protein sequence:

>665_residues
MPYETLQDIEILFGLALITVILFRRLMFPSIVGFMATGILAGPHALGFIKNSHQVEQMAEIGVVLLLFTIGIELSLKELM
RIRHLVLLGGGLQVLVTILVVAGVAMLGGFPANQSVFFGFLVALSSTAILMKLLIDSGQADTPHGKMAMGILIFQDLCIV
PLMLLTPLLAGGGDGAREIVLIGAKAAAVVVMAHYGARFLVPWIFKQVVRTRSRELFILTIIFIGLGTAWLTALAGLSLA
LGAFIAGLAISESEYSHQALGDIIPFREAFMSLFFISVGMLLDPAILLKHPLLIASLVAAILLIKTLVTSGAGMALGVST
RITVITALSLAQIGEFSFVLSQSGVNLGILTPDMYQIFLAASIATMGLTPACLGFAPAVAERISTLLPRRWSRGRGVLAS
HDRPVAMSDHVIIVGYGVNGRNLSRVLKSQKIQHLVIETNPFTVRSEARKGHKIHFGDASKPEVLEHAHVDRARVLVVAI
SDAAASRRVAGMARQMNPALHIIVRTRYVLEVEPLFKLGVNEVVPEEFETSVEIFSRVLRNYLVPQHDVDRCIAEVRSDG
YDMLRSLSRRHSHAMGISGYLSGAEIGTFRVREGSQLEARSLREGTIRNMSGATVLVIKRGEEVVPNPDPVWELRRDDLV
LLLGSAEQLAAAGRLFEPTPHLRQA

Sequences:

>Translated_665_residues
MPYETLQDIEILFGLALITVILFRRLMFPSIVGFMATGILAGPHALGFIKNSHQVEQMAEIGVVLLLFTIGIELSLKELM
RIRHLVLLGGGLQVLVTILVVAGVAMLGGFPANQSVFFGFLVALSSTAILMKLLIDSGQADTPHGKMAMGILIFQDLCIV
PLMLLTPLLAGGGDGAREIVLIGAKAAAVVVMAHYGARFLVPWIFKQVVRTRSRELFILTIIFIGLGTAWLTALAGLSLA
LGAFIAGLAISESEYSHQALGDIIPFREAFMSLFFISVGMLLDPAILLKHPLLIASLVAAILLIKTLVTSGAGMALGVST
RITVITALSLAQIGEFSFVLSQSGVNLGILTPDMYQIFLAASIATMGLTPACLGFAPAVAERISTLLPRRWSRGRGVLAS
HDRPVAMSDHVIIVGYGVNGRNLSRVLKSQKIQHLVIETNPFTVRSEARKGHKIHFGDASKPEVLEHAHVDRARVLVVAI
SDAAASRRVAGMARQMNPALHIIVRTRYVLEVEPLFKLGVNEVVPEEFETSVEIFSRVLRNYLVPQHDVDRCIAEVRSDG
YDMLRSLSRRHSHAMGISGYLSGAEIGTFRVREGSQLEARSLREGTIRNMSGATVLVIKRGEEVVPNPDPVWELRRDDLV
LLLGSAEQLAAAGRLFEPTPHLRQA
>Mature_664_residues
PYETLQDIEILFGLALITVILFRRLMFPSIVGFMATGILAGPHALGFIKNSHQVEQMAEIGVVLLLFTIGIELSLKELMR
IRHLVLLGGGLQVLVTILVVAGVAMLGGFPANQSVFFGFLVALSSTAILMKLLIDSGQADTPHGKMAMGILIFQDLCIVP
LMLLTPLLAGGGDGAREIVLIGAKAAAVVVMAHYGARFLVPWIFKQVVRTRSRELFILTIIFIGLGTAWLTALAGLSLAL
GAFIAGLAISESEYSHQALGDIIPFREAFMSLFFISVGMLLDPAILLKHPLLIASLVAAILLIKTLVTSGAGMALGVSTR
ITVITALSLAQIGEFSFVLSQSGVNLGILTPDMYQIFLAASIATMGLTPACLGFAPAVAERISTLLPRRWSRGRGVLASH
DRPVAMSDHVIIVGYGVNGRNLSRVLKSQKIQHLVIETNPFTVRSEARKGHKIHFGDASKPEVLEHAHVDRARVLVVAIS
DAAASRRVAGMARQMNPALHIIVRTRYVLEVEPLFKLGVNEVVPEEFETSVEIFSRVLRNYLVPQHDVDRCIAEVRSDGY
DMLRSLSRRHSHAMGISGYLSGAEIGTFRVREGSQLEARSLREGTIRNMSGATVLVIKRGEEVVPNPDPVWELRRDDLVL
LLGSAEQLAAAGRLFEPTPHLRQA

Specific function: Transport system that facilitates potassium-efflux, possibly by potassium-proton antiport [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI157388921, Length=358, Percent_Identity=28.2122905027933, Blast_Score=107, Evalue=4e-23,
Organism=Escherichia coli, GI1786685, Length=527, Percent_Identity=33.7760910815939, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1789749, Length=565, Percent_Identity=30.7964601769912, Blast_Score=235, Evalue=5e-63,
Organism=Escherichia coli, GI1786232, Length=535, Percent_Identity=31.0280373831776, Blast_Score=213, Evalue=3e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR020884
- InterPro:   IPR004771
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 72067; Mature: 71936

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYETLQDIEILFGLALITVILFRRLMFPSIVGFMATGILAGPHALGFIKNSHQVEQMAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHH
IGVVLLLFTIGIELSLKELMRIRHLVLLGGGLQVLVTILVVAGVAMLGGFPANQSVFFGF
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LVALSSTAILMKLLIDSGQADTPHGKMAMGILIFQDLCIVPLMLLTPLLAGGGDGAREIV
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
LIGAKAAAVVVMAHYGARFLVPWIFKQVVRTRSRELFILTIIFIGLGTAWLTALAGLSLA
EEECHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LGAFIAGLAISESEYSHQALGDIIPFREAFMSLFFISVGMLLDPAILLKHPLLIASLVAA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ILLIKTLVTSGAGMALGVSTRITVITALSLAQIGEFSFVLSQSGVNLGILTPDMYQIFLA
HHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCHHEEEECCCCEEEEECHHHHHHHHH
ASIATMGLTPACLGFAPAVAERISTLLPRRWSRGRGVLASHDRPVAMSDHVIIVGYGVNG
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCEEECCCCCEEECCCEEEEEECCCC
RNLSRVLKSQKIQHLVIETNPFTVRSEARKGHKIHFGDASKPEVLEHAHVDRARVLVVAI
HHHHHHHHHHCCCEEEEECCCCEEEHHCCCCCEEECCCCCCCHHHHHHCCCCEEEEEEEE
SDAAASRRVAGMARQMNPALHIIVRTRYVLEVEPLFKLGVNEVVPEEFETSVEIFSRVLR
CCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECHHHHCCCHHCCCHHHHHHHHHHHHHHH
NYLVPQHDVDRCIAEVRSDGYDMLRSLSRRHSHAMGISGYLSGAEIGTFRVREGSQLEAR
HHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHCCCCCCEEEEEECCCCCHHHH
SLREGTIRNMSGATVLVIKRGEEVVPNPDPVWELRRDDLVLLLGSAEQLAAAGRLFEPTP
HHHHCCCCCCCCCEEEEEECCCCCCCCCCCCHHCCCCCEEEEECCHHHHHHCCCCCCCCC
HLRQA
HHCCC
>Mature Secondary Structure 
PYETLQDIEILFGLALITVILFRRLMFPSIVGFMATGILAGPHALGFIKNSHQVEQMAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHH
IGVVLLLFTIGIELSLKELMRIRHLVLLGGGLQVLVTILVVAGVAMLGGFPANQSVFFGF
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LVALSSTAILMKLLIDSGQADTPHGKMAMGILIFQDLCIVPLMLLTPLLAGGGDGAREIV
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
LIGAKAAAVVVMAHYGARFLVPWIFKQVVRTRSRELFILTIIFIGLGTAWLTALAGLSLA
EEECHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LGAFIAGLAISESEYSHQALGDIIPFREAFMSLFFISVGMLLDPAILLKHPLLIASLVAA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ILLIKTLVTSGAGMALGVSTRITVITALSLAQIGEFSFVLSQSGVNLGILTPDMYQIFLA
HHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCHHEEEECCCCEEEEECHHHHHHHHH
ASIATMGLTPACLGFAPAVAERISTLLPRRWSRGRGVLASHDRPVAMSDHVIIVGYGVNG
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCEEECCCCCEEECCCEEEEEECCCC
RNLSRVLKSQKIQHLVIETNPFTVRSEARKGHKIHFGDASKPEVLEHAHVDRARVLVVAI
HHHHHHHHHHCCCEEEEECCCCEEEHHCCCCCEEECCCCCCCHHHHHHCCCCEEEEEEEE
SDAAASRRVAGMARQMNPALHIIVRTRYVLEVEPLFKLGVNEVVPEEFETSVEIFSRVLR
CCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECHHHHCCCHHCCCHHHHHHHHHHHHHHH
NYLVPQHDVDRCIAEVRSDGYDMLRSLSRRHSHAMGISGYLSGAEIGTFRVREGSQLEAR
HHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHCCCCCCEEEEEECCCCCHHHH
SLREGTIRNMSGATVLVIKRGEEVVPNPDPVWELRRDDLVLLLGSAEQLAAAGRLFEPTP
HHHHCCCCCCCCCEEEEEECCCCCCCCCCCCHHCCCCCEEEEECCHHHHHHCCCCCCCCC
HLRQA
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA