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The map label for this gene is rpoC

Identifier: 118579113

GI number: 118579113

Start: 713485

End: 717714

Strand: Direct

Name: rpoC

Synonym: Ppro_0674

Alternate gene names: 118579113

Gene position: 713485-717714 (Clockwise)

Preceding gene: 118579112

Following gene: 118579114

Centisome position: 17.8

GC content: 55.86

Gene sequence:

>4230_bases
GTGGAAGACTACTTCAGCTTCTTTGATAAACCCAAAGATCCGCTCCATTTTTCAGCAATTCGGATTTCCGTTTCCTCGCC
GGAAAAGATCCGTGAGCGGTCCCACGGCGAAGTAAAAAAGCCAGAGACCATAAATTACCGGACGTTCAAGCCGGAACGGG
ATGGCCTGTTCTGCGCAAAAATATTTGGCCCGACCAAAGACTACGAGTGCAATTGCGGCAAATACAAGCGCATGAAGCAC
CGCGGTATTATCTGTGAAAAGTGCGGCGTCGAGGTTATTCCGTCCAAGGTCCGTCGCGAGCGACTCGGACATATCGACCT
TGCCACACCGGTCGCTCATATCTGGTTCCTCAAGTCGCTGCCGTCGCGCATCGGCAACCTGCTTGACATCACCCTCAAGG
ATCTGGAAAAGGTCCTCTACTTTGAGGCCTTCGTTATCAGCGATCCCAAGAACAGTCCGCTCCAATTCTGCGAGGTGATG
TCTGAGGACAAATTTCTCAAGGCTCAGCAGGAATATGGCTACGATGCCTTTTCAGGCGGCATGGGTGCCGAGGCCATCCG
CGAGTGTCTGAAAGCCATCGATCTGGACGAACTCTCCGGTCAGTTGCGCACCGAGATGATGGAGTCCACCAGCGAGGCCA
AGCGCAAGAAAACTGCCAAGCGCCTGAAGGTGCTGGAGGCATTCAAGTCTTCGGGAAACAAACCAGAATGGATGATCCTG
GAATGTATCCCGGTCCTGCCGCCCGAGTTGCGCCCCCTGGTGCCCCTGGACGGTGGTCGCTTTGCAACATCAGACCTCAA
CGATCTGTACCGCCGAGTTATCAATCGCAACAACCGTCTGAAGCGATTGGTGGAGCTTCAGGCGCCTGAGGTTATCATCC
GCAATGAAAAGCGCATGCTGCAGGAGGCCGTGGATGCTCTGTTCGACAACGGCCGCCGCGGCAGGGCGATCGCGGGTCCC
AACAAGCGGCCGCTGAAATCCCTCTCCGACATGCTCAAGGGAAAATCCGGCCGTTTCCGTCAGAACCTGCTGGGAAAGCG
CGTCGATTATTCCGGACGTTCAGTTATCGTTGTCGGCCCGGAACTGAAGTTGCACCAGTGCGGTCTTCCCAAGAAAATGG
CCCTGGAACTGTTCAAGCCTTTCATCTACAACAAGCTTGAGGAGCGCGGCTACGTCACCACTATCAAGAGCGCTAAGAAG
ATGGTGGAGAAGGAGCGCCCCGAGGTGTGGGACGTGCTGGAGGAGGTTATCAGGGAGCACCCGGTCATGCTCAACCGCGC
TCCCACACTGCACCGCCTCGGCATCCAGGCCTTTGAGCCGGTATTGATCGAGGGCAAGGCTATCCAGCTTCACCCGCTGG
TCTGTACCGCATTCAACGCCGACTTCGACGGCGACCAGATGGCGGTACATCTCCCGCTTTCCGTGGAGAGCCAGGTGGAA
GCTCGCGTCCTGATGATGTCCACCAATAATATCCTCTCGCCGGCCCACGGCAAGCCGATCATCGTGCCTTCCCAGGACAT
GGTTCTGGGAGCCTACTACATGACTCGTGACAGGCGCTTCGAGCGCGTGATAGACGAGACGACCGGCAAGGAGAAGATCG
ATGCGGAAAGCGGTCTGCCGATCTACCGCAAGGTAAAGGGCACCGGCAAGGTCTTTTCCGGTCCAGACGAGGTTCGCATC
GCCTTTGACGCCGGTGAGGTCGACATGCAGGCCACCGTCAAGGTGCGCATGAAGAATCTGGTCAGCGACGAAAAACCGCA
GATGATCGACACCACTGTGGGGCGCGTTATTCTCAAGGAGATACTGCCGGATTCGGTACCGTTTAGCGCCGTAAACAAGG
TCATGAACAAGAAGGAACTCTCCAATCTCGTTGATACCTGTTACCGCATGGCGGACAACAAGGAGACGGTCATTCTTGCC
GACAAGCTGAAAGACATCGGCTTCCGTTACGCCAACCTGGCAGGGATTTCCATCTGTCTCGACGACATGGTCATCCCGGA
GGGCAAAACCGAGATTCTCACCAAGGCTGAGGACGAGGTTAAGGAAATTCAGAACCAGTATACCGAAGGTCTGATTACCG
ATGGCGAACGCTACAACAAGGTCATCGACATCTGGGCTAAAGCTACCGAGGATATTGCCAAGGAGATGCTTGATAACCTT
TCCAAGGAAAAATTCTTCGTCGAAGGGGTAGGCGTTTCTGAGGAGGCCTCGTTCAACGCCATTCATATGATGGCTGATTC
AGGAGCGAGGGGTTCGCACCAGCAGATTCGTCAGCTGGCCGGCATGCGCGGCCTTATGGCTAAGCCGTCGGGCGAGATTA
TTGAAACGCCGATTACCGCCAACTTCCGTGAAGGATTGACGGTGCTGCAGTACTTCATCTCAACCCATGGTGCACGAAAG
GGTCTGGCTGACACAGCCCTCAAAACGGCAAACTCCGGATACCTGACCCGTCGTCTGGTGGACGTTGCTCAGGATGCCAT
CATTGCTGAGGAAGATTGCGGCACGCTCGATGGCCTGGTTGTGTCGTCCCTCACCGAGGGGGGCGAGGTTATCGAGCATA
TCGGAGACCGCATTCTCGGCCGCGTGGCTCTGGATGACATCCTCGACCCGATTACCGGAGACGTACTTGTTGCTGCTAAC
GAGGATATCGATGAGAACCTGGTCAAGCGCATCGAGGATGCAGGACTTGAGAAGGTCAAGATCCGCTCCGTGCTTACCTG
TCAGAGTCGGCGCGGCATCTGCTCCAAATGCTACGGTCGAGACCTGGCGCGCGGTCACAGCGTCAATATGGGTGAGGCCG
TGGGAGTCATTGCGGCGCAGTCCATCGGCGAACCGGGAACGCAGCTTACCATGCGTACATTCCACATCGGCGGTACCGCG
TCCCGTCGCGCCGAGCAGACTTCGCTGGAATCTCGTACTGACGGTATTCTCAAGTTTATCAACCTGAACACGGTTATTAA
TGCCGAGGGACATCATATCGTCATGAACCGCAACGGGGAAATCGCCGTTGTGGATGAAACCGGCCGTGAACGTGAAAAAT
ATCTTGTCCTCTATGGAGCGAAAATTAAGATCGCTCCGGGGGGCGCGGTCACCCAGGGGGGCATCCTGGCCGAATGGGAT
CCCTATACCATGCCGATTCTTACCGAGTTCAGCGGTAAGGTGAAATTCGGTGACATAGTTGAGGGTGTGACCATGGAGGA
GCAGCTCGACGAAGTCACCGGCCTGTCCCGCAAGGTCATCATCGAATCGAAGGACAGCGACAAGCGCCCGCGCATTGCCA
TCAAAGGCATGGGCGGCGACTCAGCCGATGCGGTCACCGGTACCATCGGGCGCTACTTCCTCCCCGTCGGCGCAAACATC
ACGGTGCAGGACGATAGCGTCATTAGCGCCGGTGACATCATCGCCAAGATTCCCCGGGAAACGACCAAGACCAAGGACAT
TACCGGTGGTCTTCCGCGAGTGGCCGAGTTGTTCGAGGCTCGCAAGCCGAAGGACTTTGCCGTTATTTCGGAAATTGACG
GACGTGTTTCCTATGGTAAGGATGCAAAGGGGAAGCGCAAAGTCATTGTCACGCCTGAGATGGGCGAACCGAAGGAATAC
CTGATTCCAAAGGGGAAGCACATCAGCGTGCACGAGGGTGACCATGTCCGTGCCGGGGAGCCGTTGATGGATGGCTCATC
CAACCCCCATGATATCCTGCGCGTATTGGGCGTCAAGGAACTTGCCAAGTATCTGGTGGATGAGGTTCAGGAGGTGTACC
GCCTGCAGGGGGTTAAGATTAACGACAAGCATATCGAAGTAATCGTTCGCCAGATGCTGCGGCGTGTTCGCATCAAGGAT
GTGGGCGATACATCACTGCTGGTTGACGATCAGGTGGAGCGCTGGGTTTTCGAGACTGAGAACCAGAAAGTAATGAATGA
GGGCAAGCGTCCCGCCATAGCAGAACCGCTACTACTCGGCATTACCAAGGCGTCTCTTTCCACAGAATCGTTTATTTCCG
CAGCCTCGTTTCAGGAGACGACCAAGGTGCTTACGCAGGCGGCTATCGAGGGTAAAGTGGACTATCTGAGGGGCTTGAAG
GAAAATGTCATTATGGGGCGGTTGATCCCCGCTGGTACGGGGCTTTCAAGCTACCGGAACATCCGCATGCTTACGGAAGC
CAGTGAACCGGTTGCGCAGGCTGCTGAAAGTGAGGATGTTCCCGATGTGAGTCAGCAGGAAGCAGCATAG

Upstream 100 bases:

>100_bases
GTATTTCGCGTGCGAGAAGGATTCGCGCATACCGCAGACCAGCACTGTCCGCCACGCACGGCGTGACGCGCAGCTTCAGA
TATATACGGAGGAGAGCAAC

Downstream 100 bases:

>100_bases
AGATGTTTGATGAGCGCCGATGGGTAGGGTCTCCCCATCGGCGCGTGTGTTGCCCTGACTCACAAGTTTATCGGTTATTT
GTACCAACCGAATGGATGCA

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1409; Mature: 1409

Protein sequence:

>1409_residues
MEDYFSFFDKPKDPLHFSAIRISVSSPEKIRERSHGEVKKPETINYRTFKPERDGLFCAKIFGPTKDYECNCGKYKRMKH
RGIICEKCGVEVIPSKVRRERLGHIDLATPVAHIWFLKSLPSRIGNLLDITLKDLEKVLYFEAFVISDPKNSPLQFCEVM
SEDKFLKAQQEYGYDAFSGGMGAEAIRECLKAIDLDELSGQLRTEMMESTSEAKRKKTAKRLKVLEAFKSSGNKPEWMIL
ECIPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLVELQAPEVIIRNEKRMLQEAVDALFDNGRRGRAIAGP
NKRPLKSLSDMLKGKSGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKKMALELFKPFIYNKLEERGYVTTIKSAKK
MVEKERPEVWDVLEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCTAFNADFDGDQMAVHLPLSVESQVE
ARVLMMSTNNILSPAHGKPIIVPSQDMVLGAYYMTRDRRFERVIDETTGKEKIDAESGLPIYRKVKGTGKVFSGPDEVRI
AFDAGEVDMQATVKVRMKNLVSDEKPQMIDTTVGRVILKEILPDSVPFSAVNKVMNKKELSNLVDTCYRMADNKETVILA
DKLKDIGFRYANLAGISICLDDMVIPEGKTEILTKAEDEVKEIQNQYTEGLITDGERYNKVIDIWAKATEDIAKEMLDNL
SKEKFFVEGVGVSEEASFNAIHMMADSGARGSHQQIRQLAGMRGLMAKPSGEIIETPITANFREGLTVLQYFISTHGARK
GLADTALKTANSGYLTRRLVDVAQDAIIAEEDCGTLDGLVVSSLTEGGEVIEHIGDRILGRVALDDILDPITGDVLVAAN
EDIDENLVKRIEDAGLEKVKIRSVLTCQSRRGICSKCYGRDLARGHSVNMGEAVGVIAAQSIGEPGTQLTMRTFHIGGTA
SRRAEQTSLESRTDGILKFINLNTVINAEGHHIVMNRNGEIAVVDETGREREKYLVLYGAKIKIAPGGAVTQGGILAEWD
PYTMPILTEFSGKVKFGDIVEGVTMEEQLDEVTGLSRKVIIESKDSDKRPRIAIKGMGGDSADAVTGTIGRYFLPVGANI
TVQDDSVISAGDIIAKIPRETTKTKDITGGLPRVAELFEARKPKDFAVISEIDGRVSYGKDAKGKRKVIVTPEMGEPKEY
LIPKGKHISVHEGDHVRAGEPLMDGSSNPHDILRVLGVKELAKYLVDEVQEVYRLQGVKINDKHIEVIVRQMLRRVRIKD
VGDTSLLVDDQVERWVFETENQKVMNEGKRPAIAEPLLLGITKASLSTESFISAASFQETTKVLTQAAIEGKVDYLRGLK
ENVIMGRLIPAGTGLSSYRNIRMLTEASEPVAQAAESEDVPDVSQQEAA

Sequences:

>Translated_1409_residues
MEDYFSFFDKPKDPLHFSAIRISVSSPEKIRERSHGEVKKPETINYRTFKPERDGLFCAKIFGPTKDYECNCGKYKRMKH
RGIICEKCGVEVIPSKVRRERLGHIDLATPVAHIWFLKSLPSRIGNLLDITLKDLEKVLYFEAFVISDPKNSPLQFCEVM
SEDKFLKAQQEYGYDAFSGGMGAEAIRECLKAIDLDELSGQLRTEMMESTSEAKRKKTAKRLKVLEAFKSSGNKPEWMIL
ECIPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLVELQAPEVIIRNEKRMLQEAVDALFDNGRRGRAIAGP
NKRPLKSLSDMLKGKSGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKKMALELFKPFIYNKLEERGYVTTIKSAKK
MVEKERPEVWDVLEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCTAFNADFDGDQMAVHLPLSVESQVE
ARVLMMSTNNILSPAHGKPIIVPSQDMVLGAYYMTRDRRFERVIDETTGKEKIDAESGLPIYRKVKGTGKVFSGPDEVRI
AFDAGEVDMQATVKVRMKNLVSDEKPQMIDTTVGRVILKEILPDSVPFSAVNKVMNKKELSNLVDTCYRMADNKETVILA
DKLKDIGFRYANLAGISICLDDMVIPEGKTEILTKAEDEVKEIQNQYTEGLITDGERYNKVIDIWAKATEDIAKEMLDNL
SKEKFFVEGVGVSEEASFNAIHMMADSGARGSHQQIRQLAGMRGLMAKPSGEIIETPITANFREGLTVLQYFISTHGARK
GLADTALKTANSGYLTRRLVDVAQDAIIAEEDCGTLDGLVVSSLTEGGEVIEHIGDRILGRVALDDILDPITGDVLVAAN
EDIDENLVKRIEDAGLEKVKIRSVLTCQSRRGICSKCYGRDLARGHSVNMGEAVGVIAAQSIGEPGTQLTMRTFHIGGTA
SRRAEQTSLESRTDGILKFINLNTVINAEGHHIVMNRNGEIAVVDETGREREKYLVLYGAKIKIAPGGAVTQGGILAEWD
PYTMPILTEFSGKVKFGDIVEGVTMEEQLDEVTGLSRKVIIESKDSDKRPRIAIKGMGGDSADAVTGTIGRYFLPVGANI
TVQDDSVISAGDIIAKIPRETTKTKDITGGLPRVAELFEARKPKDFAVISEIDGRVSYGKDAKGKRKVIVTPEMGEPKEY
LIPKGKHISVHEGDHVRAGEPLMDGSSNPHDILRVLGVKELAKYLVDEVQEVYRLQGVKINDKHIEVIVRQMLRRVRIKD
VGDTSLLVDDQVERWVFETENQKVMNEGKRPAIAEPLLLGITKASLSTESFISAASFQETTKVLTQAAIEGKVDYLRGLK
ENVIMGRLIPAGTGLSSYRNIRMLTEASEPVAQAAESEDVPDVSQQEAA
>Mature_1409_residues
MEDYFSFFDKPKDPLHFSAIRISVSSPEKIRERSHGEVKKPETINYRTFKPERDGLFCAKIFGPTKDYECNCGKYKRMKH
RGIICEKCGVEVIPSKVRRERLGHIDLATPVAHIWFLKSLPSRIGNLLDITLKDLEKVLYFEAFVISDPKNSPLQFCEVM
SEDKFLKAQQEYGYDAFSGGMGAEAIRECLKAIDLDELSGQLRTEMMESTSEAKRKKTAKRLKVLEAFKSSGNKPEWMIL
ECIPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLVELQAPEVIIRNEKRMLQEAVDALFDNGRRGRAIAGP
NKRPLKSLSDMLKGKSGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKKMALELFKPFIYNKLEERGYVTTIKSAKK
MVEKERPEVWDVLEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCTAFNADFDGDQMAVHLPLSVESQVE
ARVLMMSTNNILSPAHGKPIIVPSQDMVLGAYYMTRDRRFERVIDETTGKEKIDAESGLPIYRKVKGTGKVFSGPDEVRI
AFDAGEVDMQATVKVRMKNLVSDEKPQMIDTTVGRVILKEILPDSVPFSAVNKVMNKKELSNLVDTCYRMADNKETVILA
DKLKDIGFRYANLAGISICLDDMVIPEGKTEILTKAEDEVKEIQNQYTEGLITDGERYNKVIDIWAKATEDIAKEMLDNL
SKEKFFVEGVGVSEEASFNAIHMMADSGARGSHQQIRQLAGMRGLMAKPSGEIIETPITANFREGLTVLQYFISTHGARK
GLADTALKTANSGYLTRRLVDVAQDAIIAEEDCGTLDGLVVSSLTEGGEVIEHIGDRILGRVALDDILDPITGDVLVAAN
EDIDENLVKRIEDAGLEKVKIRSVLTCQSRRGICSKCYGRDLARGHSVNMGEAVGVIAAQSIGEPGTQLTMRTFHIGGTA
SRRAEQTSLESRTDGILKFINLNTVINAEGHHIVMNRNGEIAVVDETGREREKYLVLYGAKIKIAPGGAVTQGGILAEWD
PYTMPILTEFSGKVKFGDIVEGVTMEEQLDEVTGLSRKVIIESKDSDKRPRIAIKGMGGDSADAVTGTIGRYFLPVGANI
TVQDDSVISAGDIIAKIPRETTKTKDITGGLPRVAELFEARKPKDFAVISEIDGRVSYGKDAKGKRKVIVTPEMGEPKEY
LIPKGKHISVHEGDHVRAGEPLMDGSSNPHDILRVLGVKELAKYLVDEVQEVYRLQGVKINDKHIEVIVRQMLRRVRIKD
VGDTSLLVDDQVERWVFETENQKVMNEGKRPAIAEPLLLGITKASLSTESFISAASFQETTKVLTQAAIEGKVDYLRGLK
ENVIMGRLIPAGTGLSSYRNIRMLTEASEPVAQAAESEDVPDVSQQEAA

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI4505939, Length=488, Percent_Identity=28.2786885245902, Blast_Score=157, Evalue=8e-38,
Organism=Homo sapiens, GI39725938, Length=740, Percent_Identity=27.2972972972973, Blast_Score=157, Evalue=1e-37,
Organism=Homo sapiens, GI103471997, Length=774, Percent_Identity=25.3229974160207, Blast_Score=126, Evalue=2e-28,
Organism=Escherichia coli, GI2367335, Length=1422, Percent_Identity=59.563994374121, Blast_Score=1695, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145495, Length=868, Percent_Identity=26.7281105990783, Blast_Score=181, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI71987878, Length=569, Percent_Identity=26.3620386643234, Blast_Score=157, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6324690, Length=599, Percent_Identity=27.0450751252087, Blast_Score=164, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6320061, Length=555, Percent_Identity=27.7477477477477, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI17530899, Length=856, Percent_Identity=26.7523364485981, Blast_Score=178, Evalue=3e-44,
Organism=Drosophila melanogaster, GI281360912, Length=516, Percent_Identity=27.3255813953488, Blast_Score=133, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17647875, Length=688, Percent_Identity=23.546511627907, Blast_Score=120, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_PELPD (A1ALT5)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_900363.1
- ProteinModelPortal:   A1ALT5
- STRING:   A1ALT5
- GeneID:   4571913
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_0674
- eggNOG:   COG0086
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- PhylomeDB:   A1ALT5
- ProtClustDB:   PRK00566
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 156572; Mature: 156572

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDYFSFFDKPKDPLHFSAIRISVSSPEKIRERSHGEVKKPETINYRTFKPERDGLFCAK
CCCHHHHHCCCCCCCEEEEEEEECCCCHHHHHCCCCCCCCCCCCCEEECCCCCCCEEEEE
IFGPTKDYECNCGKYKRMKHRGIICEKCGVEVIPSKVRRERLGHIDLATPVAHIWFLKSL
ECCCCCCCCCCCCHHHHHHHCCCCHHHCCCHHCCHHHHHHHCCCCCHHHHHHHHHHHHHH
PSRIGNLLDITLKDLEKVLYFEAFVISDPKNSPLQFCEVMSEDKFLKAQQEYGYDAFSGG
HHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCCHHHHHHHHCCCCHHCCC
MGAEAIRECLKAIDLDELSGQLRTEMMESTSEAKRKKTAKRLKVLEAFKSSGNKPEWMIL
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
ECIPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLVELQAPEVIIRNEKRML
EEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCEECCHHHHH
QEAVDALFDNGRRGRAIAGPNKRPLKSLSDMLKGKSGRFRQNLLGKRVDYSGRSVIVVGP
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCEEEEECC
ELKLHQCGLPKKMALELFKPFIYNKLEERGYVTTIKSAKKMVEKERPEVWDVLEEVIREH
CCEEHHCCCCHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHC
PVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCTAFNADFDGDQMAVHLPLSVESQVE
CEEECCCCCHHHHCHHHCCCEEECCCEEEEEEEEEEEECCCCCCCCEEEEECCCCCCCCC
ARVLMMSTNNILSPAHGKPIIVPSQDMVLGAYYMTRDRRFERVIDETTGKEKIDAESGLP
EEEEEEECCCCCCCCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
IYRKVKGTGKVFSGPDEVRIAFDAGEVDMQATVKVRMKNLVSDEKPQMIDTTVGRVILKE
EEEEECCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
ILPDSVPFSAVNKVMNKKELSNLVDTCYRMADNKETVILADKLKDIGFRYANLAGISICL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCCHHHHHHHHEEEE
DDMVIPEGKTEILTKAEDEVKEIQNQYTEGLITDGERYNKVIDIWAKATEDIAKEMLDNL
CCEECCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
SKEKFFVEGVGVSEEASFNAIHMMADSGARGSHQQIRQLAGMRGLMAKPSGEIIETPITA
CCCEEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCC
NFREGLTVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDAIIAEEDCGTLDGLV
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCCCCHHHHH
VSSLTEGGEVIEHIGDRILGRVALDDILDPITGDVLVAANEDIDENLVKRIEDAGLEKVK
HHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEE
IRSVLTCQSRRGICSKCYGRDLARGHSVNMGEAVGVIAAQSIGEPGTQLTMRTFHIGGTA
HHHHHHHHHCCCHHHHHHCCHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEECCCC
SRRAEQTSLESRTDGILKFINLNTVINAEGHHIVMNRNGEIAVVDETGREREKYLVLYGA
HHHHHHHHHHHHHHHHEEEEEECEEEECCCCEEEEECCCCEEEEECCCCCCCCEEEEEEE
KIKIAPGGAVTQGGILAEWDPYTMPILTEFSGKVKFGDIVEGVTMEEQLDEVTGLSRKVI
EEEECCCCCCCCCCEEECCCCCCCCCEECCCCCEEECHHHCCCCHHHHHHHHHCCCEEEE
IESKDSDKRPRIAIKGMGGDSADAVTGTIGRYFLPVGANITVQDDSVISAGDIIAKIPRE
EECCCCCCCCEEEEEECCCCCCHHHHHHHHHEEEECCCEEEECCCCCCCCCHHHHHCCCC
TTKTKDITGGLPRVAELFEARKPKDFAVISEIDGRVSYGKDAKGKRKVIVTPEMGEPKEY
CCCCCCCCCCCHHHHHHHHCCCCCCEEEHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHH
LIPKGKHISVHEGDHVRAGEPLMDGSSNPHDILRVLGVKELAKYLVDEVQEVYRLQGVKI
CCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
NDKHIEVIVRQMLRRVRIKDVGDTSLLVDDQVERWVFETENQKVMNEGKRPAIAEPLLLG
CHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHE
ITKASLSTESFISAASFQETTKVLTQAAIEGKVDYLRGLKENVIMGRLIPAGTGLSSYRN
EHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHEEEEECCCCCHHHHCC
IRMLTEASEPVAQAAESEDVPDVSQQEAA
EEEEHHCCCHHHHHHCCCCCCCCHHHCCC
>Mature Secondary Structure
MEDYFSFFDKPKDPLHFSAIRISVSSPEKIRERSHGEVKKPETINYRTFKPERDGLFCAK
CCCHHHHHCCCCCCCEEEEEEEECCCCHHHHHCCCCCCCCCCCCCEEECCCCCCCEEEEE
IFGPTKDYECNCGKYKRMKHRGIICEKCGVEVIPSKVRRERLGHIDLATPVAHIWFLKSL
ECCCCCCCCCCCCHHHHHHHCCCCHHHCCCHHCCHHHHHHHCCCCCHHHHHHHHHHHHHH
PSRIGNLLDITLKDLEKVLYFEAFVISDPKNSPLQFCEVMSEDKFLKAQQEYGYDAFSGG
HHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCCHHHHHHHHCCCCHHCCC
MGAEAIRECLKAIDLDELSGQLRTEMMESTSEAKRKKTAKRLKVLEAFKSSGNKPEWMIL
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
ECIPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLVELQAPEVIIRNEKRML
EEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCEECCHHHHH
QEAVDALFDNGRRGRAIAGPNKRPLKSLSDMLKGKSGRFRQNLLGKRVDYSGRSVIVVGP
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCEEEEECC
ELKLHQCGLPKKMALELFKPFIYNKLEERGYVTTIKSAKKMVEKERPEVWDVLEEVIREH
CCEEHHCCCCHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHC
PVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCTAFNADFDGDQMAVHLPLSVESQVE
CEEECCCCCHHHHCHHHCCCEEECCCEEEEEEEEEEEECCCCCCCCEEEEECCCCCCCCC
ARVLMMSTNNILSPAHGKPIIVPSQDMVLGAYYMTRDRRFERVIDETTGKEKIDAESGLP
EEEEEEECCCCCCCCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
IYRKVKGTGKVFSGPDEVRIAFDAGEVDMQATVKVRMKNLVSDEKPQMIDTTVGRVILKE
EEEEECCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
ILPDSVPFSAVNKVMNKKELSNLVDTCYRMADNKETVILADKLKDIGFRYANLAGISICL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCCHHHHHHHHEEEE
DDMVIPEGKTEILTKAEDEVKEIQNQYTEGLITDGERYNKVIDIWAKATEDIAKEMLDNL
CCEECCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
SKEKFFVEGVGVSEEASFNAIHMMADSGARGSHQQIRQLAGMRGLMAKPSGEIIETPITA
CCCEEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCC
NFREGLTVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDAIIAEEDCGTLDGLV
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCCCCHHHHH
VSSLTEGGEVIEHIGDRILGRVALDDILDPITGDVLVAANEDIDENLVKRIEDAGLEKVK
HHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEE
IRSVLTCQSRRGICSKCYGRDLARGHSVNMGEAVGVIAAQSIGEPGTQLTMRTFHIGGTA
HHHHHHHHHCCCHHHHHHCCHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEECCCC
SRRAEQTSLESRTDGILKFINLNTVINAEGHHIVMNRNGEIAVVDETGREREKYLVLYGA
HHHHHHHHHHHHHHHHEEEEEECEEEECCCCEEEEECCCCEEEEECCCCCCCCEEEEEEE
KIKIAPGGAVTQGGILAEWDPYTMPILTEFSGKVKFGDIVEGVTMEEQLDEVTGLSRKVI
EEEECCCCCCCCCCEEECCCCCCCCCEECCCCCEEECHHHCCCCHHHHHHHHHCCCEEEE
IESKDSDKRPRIAIKGMGGDSADAVTGTIGRYFLPVGANITVQDDSVISAGDIIAKIPRE
EECCCCCCCCEEEEEECCCCCCHHHHHHHHHEEEECCCEEEECCCCCCCCCHHHHHCCCC
TTKTKDITGGLPRVAELFEARKPKDFAVISEIDGRVSYGKDAKGKRKVIVTPEMGEPKEY
CCCCCCCCCCCHHHHHHHHCCCCCCEEEHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHH
LIPKGKHISVHEGDHVRAGEPLMDGSSNPHDILRVLGVKELAKYLVDEVQEVYRLQGVKI
CCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
NDKHIEVIVRQMLRRVRIKDVGDTSLLVDDQVERWVFETENQKVMNEGKRPAIAEPLLLG
CHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHE
ITKASLSTESFISAASFQETTKVLTQAAIEGKVDYLRGLKENVIMGRLIPAGTGLSSYRN
EHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHEEEEECCCCCHHHHCC
IRMLTEASEPVAQAAESEDVPDVSQQEAA
EEEEHHCCCHHHHHHCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA