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The map label for this gene is rpoB

Identifier: 118579112

GI number: 118579112

Start: 708886

End: 713385

Strand: Direct

Name: rpoB

Synonym: Ppro_0673

Alternate gene names: 118579112

Gene position: 708886-713385 (Clockwise)

Preceding gene: 118579111

Following gene: 118579113

Centisome position: 17.69

GC content: 55.33

Gene sequence:

>4500_bases
ATGGCTTATTCGATCGCCAACAACCACCTGCTGCGTAAAACTTTTACCAAAATCAAGAATATCATCGATATTCCCAATCT
CATTGACATACAGAAGAACTCCTACCGACGTTTCCTCCAGCAGGAGGGTGTTTCCGAATCCCGAAATAACACCGGGCTTG
AAGCCGTTTTCAGAAGCGTTTTCCCGATCAAGGATTTCAGTGAAAGCGCTTCCCTCGAATACGTCTCCTATTCGCTCAGC
AAGCCAAAATACGATGTGGTCGAGTGCCATCAGAGGGGCATGACTTTCGCCGCTCCCATGAAGGTCAAGGTTCGACTGGT
TATTTGGGATACCGGTAAAGAAAGTGGCATCAGAGCAATCAAGGATATAAAAGAGCAGGAAGTTTACTTTGGTGAAATTC
CCCTGATGACTGACAACGGGACATTTATCATCAATGGCACGGAGAGGGTTATCGTCAGTCAGTTGCACCGCTCCCCCGGC
GTTTTCTACGATCATGATAAGGGCAAGACCCACTCCAGCGGAAAGGTGCTTTACTCTGCGCGCGTGATTCCTTACCGCGG
GTCCTGGCTGGATTTTGAATTTGATCATAAAGATATACTTTATGTACGTATCGATCGCCGACGCAAGATGCCGGCTACGG
TCCTGCTGAAGGCGCTTGGATACTCGGCGGAACAGCTGCTGAACTACTATTACAAGAGCGAAGAGATTTTTCTTACCGGC
GAAACGCCTTCCAAGAGCATTGACGCGGAACTGCTGACGCTTCAGAAGGCGCTGGTTGACGTGGTCGATCCGAAGAGTGG
CGAAGTCATCGTCAAGGCCAACCGCAAGTTCACCAAGGCTTCCATCAGGAAGATGGTCGAGCACGACATTAAGGCGGTAC
CCATCACCTTTGATAGCATCATCGGGCGTTACGCTTCCAGTGACGTCATCGATCCCGCAACCGGCGAGGTGCTGCTGGAG
TGCAATGAGGAAGTGACGGCAGAAAAATTCGATGAGATTAAAGCCAAGGGGGTCGAGAGCTTCCGTCTGCTGTTCATCGA
CAATCTGCACATCACCTCATCCTTCCGCGACACACTGCTGATGGACAAGATCAGCACGAATGATGAGGCACTGATCGAAA
TCTACCGTCGACTCCGTCCGGGCGATCCTCCCACGCTGAAGAGTTCACTGGCGCTTTTCGAAAATCTGTTCTTCAACCCG
GAGCGCTACGATCTCTCCGCAGTCGGCCGCTTGAAACTCAACTTCAAACTCGGTCTCAAGGTCTGGCCGGAATGCACGGT
GCTCAATGCCCCCTGCATGTTCGGTGCTGAAGACATCGCTAGCTTCGATGAACTTTTCAGGCTCCTGCTTGCAGCTGATA
ACCGCTTTTCACAGTATGTTCTGGCGCGGCTTCCCGAGGATTTCGTTAAGGTGCTGCGCAAGCACGAACCTTCACAGCCG
GTTGCGGAAAAATTGCGTGAACAGCTGCTTAAGGAACTGAATAATCTGGTCAAGGATCCTGACTTTTATCAGAAGGAACT
GTTCACCGGCCTTGCGCTCAGCCAACAGACCGTTGCGCTGACGGAAGCCATCGAAGGGGGCGTCTTCGAGGAGAACCGTC
GTGTGATCGAGGTTCTGCGCCGCAACCGGATGATCTTTGAGGACCTCTACGCCCCTGTGGTTCTGACCAGCCCCAAGAAT
GATATTCTTGAGATCGTCCGCTATCTGATCGACTTGAAGAACGGTCGCGGTGCTATCGATGATATCGATCATCTGGGCAA
TCGCCGCGTGCGCGCCGTGGGCGAACTGCTGGAGAACCAATACCGCATCGGCCTTGTCCGCATGGAGCGGGCCATCAAGG
AACGCATGAGTCTGCAGGAGGTTGAAAACCTCATGCCGCATGACCTGATCAACTCCAAACCGGTATCTGCGGTGGTCAAG
GAGTTCTTCGGCTCGTCCCAGTTATCCCAGTTCATGGACCAGACCAACCCGCTCTCCGAGGTAACCCACAAGCGCCGTCT
CTCCGCTCTGGGACCGGGTGGCCTGACGCGCGAACGCGCCGGTTTCGAAGTTCGCGACGTTCATCCGACCCATTACGGCC
GAGTCTGTCCGATTGAAACCCCCGAGGGACCAAACATCGGACTGATCGCATCTCTTTCTACCTATGCCCGGATAAACGAT
CATGGTTTCGTGGAGACCCCCTACCGTATCGTACTGGACGGCAAGCTGACCAATGAGGTCCGTTTCTTCTCAGCCCTTGA
GGAGGAGGGGCATGCCATTGCCCAGGCCAATGCCGAGGTGGACGCAGAGGGGCGCTTTGTGAACGATTATGTTTCGGCGC
GCAAGAGCGGCGAGTTCATCCTCGTTCACCGCGACGAGATCGAGCTGATGGACGTGGCTCCCAAGCAACTGGTTTCCGTT
GCTGCCGCACTCATCCCGTTCCTTGAAAACGACGACGCCAACCGCGCGCTGATGGGCTCCAACATGCAGCGTCAGGCCGT
TCCGCTGCTGCGCGCCGATTCACCGCTGGTCGGCACCGGCATGGAGCGCATCGTGGCCAAGGACTCCGGGGTCTCCGTGA
TAGCCCGCCATAACGGCGTGGTGGAGTCGGTCGATGCCTCCCGTATCGTTGTCAAGATCGACGAGTCCGAAGTGGATGAA
ACCGGTACCGGCGTGGACATTTACAACCTGATCAAGTTCGCCCGTTCGAACCAGAACACCTGCATCAACAATAAGCCGGT
AGTCAAGGTCGGTGATGTGGTCAAGCGGCACGATGTCATCGCCGACGGTCCCTCGACCGATATGGGGGAACTTGCCCTTG
GCCAGAATATCGTTGTGGCATTCATGCCGTGGGGCGGTTACAACTTCGAGGACTCCATCCTGGTATCCGAGAAACTGGTC
AAGGATGATCGCTATACCTCCATCCACATAGAAGAGTACGAGTGCGTGGCGCGCGACACCAAGCTCGGTAAGGAAGAGAT
TACCTCCGATATTCCCAACCTGGGAGAGGAAGCTCTCAAGGACCTCGACGAATCGGGCATCATTCGCATCGGCGCCGAGG
TAAAGCCGGGTGATATCCTGGTGGGCAAGATCACTCCCAAGGGAGAAACCCAGCTTTCGCCCGAGGAGAAACTGCTGCGG
GCCATCTTCGGCGAGAAGGCCGGCGATGTGCGTGATACCTCCCTGACCGTTCCCCCCGGTGTCGAGGGGACGGTCATCGG
TGCCAAGGTGTTTTCTCGCAAGGGAGCCGACAAGGATACCCGCACGGAACTCATCGAGAAGGCCGAAGAGGAGAAACTGC
GCAAGGATGAGCAGGATGAGATCAGGATTATCCGCCAGTCTGCGGAAGGCAAGCTTCATCGTCTGCTGATCGGAAAATCT
TTGTCCGTCAAGTTGGAGGACGGCGAAGGGAACCTCATTCTGGCCAAGGGCAAGGAAATTACTGCCGAGGCCCTGAAATC
CCTTTCCATCAACGACATGGGCGCAATCTCGGTGAGCGACGATGGCCAAACCGATGACAATGTCAGCAAGGTCATCGATA
CGCTCAACCGCCAGATAGAGCTTATTCAGAGCGTGTTCGAAGACAAGATTCAGAAGCTTCGACGCGGCGATGACCTTCCT
CCCGGGGTCATCAAGATGGTCAAGGTGTACATCGCCATCAAGCGCAAACTGCAGGTGGGCGACAAGATGGCAGGTCGCCA
CGGCAATAAGGGTGTTGTATCGCGCATCCTGCCCGAAGAGGACATGCCCTACATGGAGGACGGGCGGCCGGTGGAGATCG
TCCTCAATCCCCTGGGTGTTCCCTCTCGTATGAACGTGGGCCAGATTCTTGAGACGCACCTCGGTTGGGCGGCAAAGGGG
ATCGGCTGGCGCATTGAGGAGATGCTCCAAAAACAGACATCCGCAGAGAGCCTGAAGGCGTATCTCAAAGATGTCTACGG
CGACGACGAGGTTGGAACGTTCATAGATGGCATGGACCAGGAAGAACTCATGCTGGTCTGCAGGCGTCTCCAGCGCGGTG
TATCCATGGCCTCCCCGGTTTTTGAGGGGGCTTCCGAAGACAAGATCAAGTCTATGCTCGGCAAGGCCGGATTTCACTCC
TCCGGGCAGGTTACTCTGTTTGATGGCCGTTCCGGCGACCCGTTCAAGCACAAGGTCACCGTTGGTGTTATGTACGTTCT
CAAGCTGCACCATTTGGTCGATGACAAGATCCATGCCCGTTCCATTGGCCCCTACAGCCTGGTTACCCAGCAACCACTGG
GTGGCAAGGCCCAGTTCGGCGGCCAGCGTCTGGGCGAAATGGAGGTTTGGGCCATGGAGGCGTATGGCGCGGCCTACGCC
CTGCAGGAATTCCTCACCGTCAAGTCCGATGACGTGTCCGGTCGTACGCGTATGTACGAAGCCATTGTCAAAGGCAAACA
TACGCTCGAACCGGGCTTGCCCGAATCCTTTAACGTTCTTATCAAGGAATTGCAGTCGCTCTGCCTTGATGTAGAGTTGC
TAGAAGGCGAAGACGAATAG

Upstream 100 bases:

>100_bases
TCCTGTTTGGGCGGTTGCCCAACACTCCTGCAATCAGTAACTCCAGCCGGTAATCCCTCTTCGGCCGGATGTCGTCACGA
TAATCGCCAAAGGAGAAGCT

Downstream 100 bases:

>100_bases
TATTTCGCGTGCGAGAAGGATTCGCGCATACCGCAGACCAGCACTGTCCGCCACGCACGGCGTGACGCGCAGCTTCAGAT
ATATACGGAGGAGAGCAACG

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta

Number of amino acids: Translated: 1499; Mature: 1498

Protein sequence:

>1499_residues
MAYSIANNHLLRKTFTKIKNIIDIPNLIDIQKNSYRRFLQQEGVSESRNNTGLEAVFRSVFPIKDFSESASLEYVSYSLS
KPKYDVVECHQRGMTFAAPMKVKVRLVIWDTGKESGIRAIKDIKEQEVYFGEIPLMTDNGTFIINGTERVIVSQLHRSPG
VFYDHDKGKTHSSGKVLYSARVIPYRGSWLDFEFDHKDILYVRIDRRRKMPATVLLKALGYSAEQLLNYYYKSEEIFLTG
ETPSKSIDAELLTLQKALVDVVDPKSGEVIVKANRKFTKASIRKMVEHDIKAVPITFDSIIGRYASSDVIDPATGEVLLE
CNEEVTAEKFDEIKAKGVESFRLLFIDNLHITSSFRDTLLMDKISTNDEALIEIYRRLRPGDPPTLKSSLALFENLFFNP
ERYDLSAVGRLKLNFKLGLKVWPECTVLNAPCMFGAEDIASFDELFRLLLAADNRFSQYVLARLPEDFVKVLRKHEPSQP
VAEKLREQLLKELNNLVKDPDFYQKELFTGLALSQQTVALTEAIEGGVFEENRRVIEVLRRNRMIFEDLYAPVVLTSPKN
DILEIVRYLIDLKNGRGAIDDIDHLGNRRVRAVGELLENQYRIGLVRMERAIKERMSLQEVENLMPHDLINSKPVSAVVK
EFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLIASLSTYARIND
HGFVETPYRIVLDGKLTNEVRFFSALEEEGHAIAQANAEVDAEGRFVNDYVSARKSGEFILVHRDEIELMDVAPKQLVSV
AAALIPFLENDDANRALMGSNMQRQAVPLLRADSPLVGTGMERIVAKDSGVSVIARHNGVVESVDASRIVVKIDESEVDE
TGTGVDIYNLIKFARSNQNTCINNKPVVKVGDVVKRHDVIADGPSTDMGELALGQNIVVAFMPWGGYNFEDSILVSEKLV
KDDRYTSIHIEEYECVARDTKLGKEEITSDIPNLGEEALKDLDESGIIRIGAEVKPGDILVGKITPKGETQLSPEEKLLR
AIFGEKAGDVRDTSLTVPPGVEGTVIGAKVFSRKGADKDTRTELIEKAEEEKLRKDEQDEIRIIRQSAEGKLHRLLIGKS
LSVKLEDGEGNLILAKGKEITAEALKSLSINDMGAISVSDDGQTDDNVSKVIDTLNRQIELIQSVFEDKIQKLRRGDDLP
PGVIKMVKVYIAIKRKLQVGDKMAGRHGNKGVVSRILPEEDMPYMEDGRPVEIVLNPLGVPSRMNVGQILETHLGWAAKG
IGWRIEEMLQKQTSAESLKAYLKDVYGDDEVGTFIDGMDQEELMLVCRRLQRGVSMASPVFEGASEDKIKSMLGKAGFHS
SGQVTLFDGRSGDPFKHKVTVGVMYVLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRLGEMEVWAMEAYGAAYA
LQEFLTVKSDDVSGRTRMYEAIVKGKHTLEPGLPESFNVLIKELQSLCLDVELLEGEDE

Sequences:

>Translated_1499_residues
MAYSIANNHLLRKTFTKIKNIIDIPNLIDIQKNSYRRFLQQEGVSESRNNTGLEAVFRSVFPIKDFSESASLEYVSYSLS
KPKYDVVECHQRGMTFAAPMKVKVRLVIWDTGKESGIRAIKDIKEQEVYFGEIPLMTDNGTFIINGTERVIVSQLHRSPG
VFYDHDKGKTHSSGKVLYSARVIPYRGSWLDFEFDHKDILYVRIDRRRKMPATVLLKALGYSAEQLLNYYYKSEEIFLTG
ETPSKSIDAELLTLQKALVDVVDPKSGEVIVKANRKFTKASIRKMVEHDIKAVPITFDSIIGRYASSDVIDPATGEVLLE
CNEEVTAEKFDEIKAKGVESFRLLFIDNLHITSSFRDTLLMDKISTNDEALIEIYRRLRPGDPPTLKSSLALFENLFFNP
ERYDLSAVGRLKLNFKLGLKVWPECTVLNAPCMFGAEDIASFDELFRLLLAADNRFSQYVLARLPEDFVKVLRKHEPSQP
VAEKLREQLLKELNNLVKDPDFYQKELFTGLALSQQTVALTEAIEGGVFEENRRVIEVLRRNRMIFEDLYAPVVLTSPKN
DILEIVRYLIDLKNGRGAIDDIDHLGNRRVRAVGELLENQYRIGLVRMERAIKERMSLQEVENLMPHDLINSKPVSAVVK
EFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLIASLSTYARIND
HGFVETPYRIVLDGKLTNEVRFFSALEEEGHAIAQANAEVDAEGRFVNDYVSARKSGEFILVHRDEIELMDVAPKQLVSV
AAALIPFLENDDANRALMGSNMQRQAVPLLRADSPLVGTGMERIVAKDSGVSVIARHNGVVESVDASRIVVKIDESEVDE
TGTGVDIYNLIKFARSNQNTCINNKPVVKVGDVVKRHDVIADGPSTDMGELALGQNIVVAFMPWGGYNFEDSILVSEKLV
KDDRYTSIHIEEYECVARDTKLGKEEITSDIPNLGEEALKDLDESGIIRIGAEVKPGDILVGKITPKGETQLSPEEKLLR
AIFGEKAGDVRDTSLTVPPGVEGTVIGAKVFSRKGADKDTRTELIEKAEEEKLRKDEQDEIRIIRQSAEGKLHRLLIGKS
LSVKLEDGEGNLILAKGKEITAEALKSLSINDMGAISVSDDGQTDDNVSKVIDTLNRQIELIQSVFEDKIQKLRRGDDLP
PGVIKMVKVYIAIKRKLQVGDKMAGRHGNKGVVSRILPEEDMPYMEDGRPVEIVLNPLGVPSRMNVGQILETHLGWAAKG
IGWRIEEMLQKQTSAESLKAYLKDVYGDDEVGTFIDGMDQEELMLVCRRLQRGVSMASPVFEGASEDKIKSMLGKAGFHS
SGQVTLFDGRSGDPFKHKVTVGVMYVLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRLGEMEVWAMEAYGAAYA
LQEFLTVKSDDVSGRTRMYEAIVKGKHTLEPGLPESFNVLIKELQSLCLDVELLEGEDE
>Mature_1498_residues
AYSIANNHLLRKTFTKIKNIIDIPNLIDIQKNSYRRFLQQEGVSESRNNTGLEAVFRSVFPIKDFSESASLEYVSYSLSK
PKYDVVECHQRGMTFAAPMKVKVRLVIWDTGKESGIRAIKDIKEQEVYFGEIPLMTDNGTFIINGTERVIVSQLHRSPGV
FYDHDKGKTHSSGKVLYSARVIPYRGSWLDFEFDHKDILYVRIDRRRKMPATVLLKALGYSAEQLLNYYYKSEEIFLTGE
TPSKSIDAELLTLQKALVDVVDPKSGEVIVKANRKFTKASIRKMVEHDIKAVPITFDSIIGRYASSDVIDPATGEVLLEC
NEEVTAEKFDEIKAKGVESFRLLFIDNLHITSSFRDTLLMDKISTNDEALIEIYRRLRPGDPPTLKSSLALFENLFFNPE
RYDLSAVGRLKLNFKLGLKVWPECTVLNAPCMFGAEDIASFDELFRLLLAADNRFSQYVLARLPEDFVKVLRKHEPSQPV
AEKLREQLLKELNNLVKDPDFYQKELFTGLALSQQTVALTEAIEGGVFEENRRVIEVLRRNRMIFEDLYAPVVLTSPKND
ILEIVRYLIDLKNGRGAIDDIDHLGNRRVRAVGELLENQYRIGLVRMERAIKERMSLQEVENLMPHDLINSKPVSAVVKE
FFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLIASLSTYARINDH
GFVETPYRIVLDGKLTNEVRFFSALEEEGHAIAQANAEVDAEGRFVNDYVSARKSGEFILVHRDEIELMDVAPKQLVSVA
AALIPFLENDDANRALMGSNMQRQAVPLLRADSPLVGTGMERIVAKDSGVSVIARHNGVVESVDASRIVVKIDESEVDET
GTGVDIYNLIKFARSNQNTCINNKPVVKVGDVVKRHDVIADGPSTDMGELALGQNIVVAFMPWGGYNFEDSILVSEKLVK
DDRYTSIHIEEYECVARDTKLGKEEITSDIPNLGEEALKDLDESGIIRIGAEVKPGDILVGKITPKGETQLSPEEKLLRA
IFGEKAGDVRDTSLTVPPGVEGTVIGAKVFSRKGADKDTRTELIEKAEEEKLRKDEQDEIRIIRQSAEGKLHRLLIGKSL
SVKLEDGEGNLILAKGKEITAEALKSLSINDMGAISVSDDGQTDDNVSKVIDTLNRQIELIQSVFEDKIQKLRRGDDLPP
GVIKMVKVYIAIKRKLQVGDKMAGRHGNKGVVSRILPEEDMPYMEDGRPVEIVLNPLGVPSRMNVGQILETHLGWAAKGI
GWRIEEMLQKQTSAESLKAYLKDVYGDDEVGTFIDGMDQEELMLVCRRLQRGVSMASPVFEGASEDKIKSMLGKAGFHSS
GQVTLFDGRSGDPFKHKVTVGVMYVLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRLGEMEVWAMEAYGAAYAL
QEFLTVKSDDVSGRTRMYEAIVKGKHTLEPGLPESFNVLIKELQSLCLDVELLEGEDE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family

Homologues:

Organism=Homo sapiens, GI238908505, Length=292, Percent_Identity=29.7945205479452, Blast_Score=130, Evalue=1e-29,
Organism=Homo sapiens, GI238908503, Length=292, Percent_Identity=29.7945205479452, Blast_Score=130, Evalue=1e-29,
Organism=Homo sapiens, GI4505941, Length=246, Percent_Identity=31.3008130081301, Blast_Score=124, Evalue=8e-28,
Organism=Homo sapiens, GI33469941, Length=257, Percent_Identity=30.7392996108949, Blast_Score=123, Evalue=2e-27,
Organism=Homo sapiens, GI212286172, Length=257, Percent_Identity=30.7392996108949, Blast_Score=122, Evalue=2e-27,
Organism=Escherichia coli, GI1790419, Length=986, Percent_Identity=59.8377281947262, Blast_Score=1187, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552304, Length=246, Percent_Identity=31.3008130081301, Blast_Score=123, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI25144348, Length=292, Percent_Identity=30.4794520547945, Blast_Score=122, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17506623, Length=246, Percent_Identity=30.0813008130081, Blast_Score=114, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6324781, Length=292, Percent_Identity=30.1369863013699, Blast_Score=125, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6325267, Length=247, Percent_Identity=29.9595141700405, Blast_Score=123, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6324725, Length=268, Percent_Identity=30.9701492537313, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI17647877, Length=293, Percent_Identity=29.6928327645051, Blast_Score=121, Evalue=3e-27,
Organism=Drosophila melanogaster, GI17136444, Length=246, Percent_Identity=29.6747967479675, Blast_Score=117, Evalue=4e-26,
Organism=Drosophila melanogaster, GI17136446, Length=253, Percent_Identity=30.8300395256917, Blast_Score=107, Evalue=7e-23,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): RPOB_PELPD (A1ALT4)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_900362.1
- STRING:   A1ALT4
- GeneID:   4571912
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_0673
- eggNOG:   COG0085
- HOGENOM:   HBG285547
- OMA:   FMTWEGY
- PhylomeDB:   A1ALT4
- ProtClustDB:   PRK00405
- HAMAP:   MF_01321
- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- Gene3D:   G3DSA:2.40.50.150
- PANTHER:   PTHR20856
- TIGRFAMs:   TIGR02013

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7

EC number: =2.7.7.6

Molecular weight: Translated: 167646; Mature: 167515

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYSIANNHLLRKTFTKIKNIIDIPNLIDIQKNSYRRFLQQEGVSESRNNTGLEAVFRSV
CCEECCCCHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
FPIKDFSESASLEYVSYSLSKPKYDVVECHQRGMTFAAPMKVKVRLVIWDTGKESGIRAI
CCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCEEECCCEEEEEEEEEECCCCCCHHHH
KDIKEQEVYFGEIPLMTDNGTFIINGTERVIVSQLHRSPGVFYDHDKGKTHSSGKVLYSA
HHHHHHCEEECCCEEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEE
RVIPYRGSWLDFEFDHKDILYVRIDRRRKMPATVLLKALGYSAEQLLNYYYKSEEIFLTG
EEEEECCCEEEEEECCCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHCCCEEEEEC
ETPSKSIDAELLTLQKALVDVVDPKSGEVIVKANRKFTKASIRKMVEHDIKAVPITFDSI
CCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEEEHHHH
IGRYASSDVIDPATGEVLLECNEEVTAEKFDEIKAKGVESFRLLFIDNLHITSSFRDTLL
HHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCEEEEEEEECEEEECHHHHHHH
MDKISTNDEALIEIYRRLRPGDPPTLKSSLALFENLFFNPERYDLSAVGRLKLNFKLGLK
HHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEECCE
VWPECTVLNAPCMFGAEDIASFDELFRLLLAADNRFSQYVLARLPEDFVKVLRKHEPSQP
ECCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHCCCCCH
VAEKLREQLLKELNNLVKDPDFYQKELFTGLALSQQTVALTEAIEGGVFEENRRVIEVLR
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHH
RNRMIFEDLYAPVVLTSPKNDILEIVRYLIDLKNGRGAIDDIDHLGNRRVRAVGELLENQ
HCCHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHCH
YRIGLVRMERAIKERMSLQEVENLMPHDLINSKPVSAVVKEFFGSSQLSQFMDQTNPLSE
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHCHHHHHHHHHCCCCHHH
VTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLIASLSTYARIND
HHHHHHHHHCCCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEHHHHEEECC
HGFVETPYRIVLDGKLTNEVRFFSALEEEGHAIAQANAEVDAEGRFVNDYVSARKSGEFI
CCCEECCEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHCCCCCEE
LVHRDEIELMDVAPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLLRADSPLVGTG
EEECCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHCCHHCCCCCCCCCC
MERIVAKDSGVSVIARHNGVVESVDASRIVVKIDESEVDETGTGVDIYNLIKFARSNQNT
HHHHHCCCCCCEEEEECCCCEECCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCC
CINNKPVVKVGDVVKRHDVIADGPSTDMGELALGQNIVVAFMPWGGYNFEDSILVSEKLV
CCCCCCCEEHHHHHHHCCCCCCCCCCCCHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHH
KDDRYTSIHIEEYECVARDTKLGKEEITSDIPNLGEEALKDLDESGIIRIGAEVKPGDIL
CCCCCEEEEEEHHHHHHHHHHCCHHHHHHHCCCCCHHHHHCCCCCCEEEECCCCCCCCEE
VGKITPKGETQLSPEEKLLRAIFGEKAGDVRDTSLTVPPGVEGTVIGAKVFSRKGADKDT
EEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCEEEHHHHHHCCCCCCHH
RTELIEKAEEEKLRKDEQDEIRIIRQSAEGKLHRLLIGKSLSVKLEDGEGNLILAKGKEI
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCCEEEECCCHH
TAEALKSLSINDMGAISVSDDGQTDDNVSKVIDTLNRQIELIQSVFEDKIQKLRRGDDLP
HHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PGVIKMVKVYIAIKRKLQVGDKMAGRHGNKGVVSRILPEEDMPYMEDGRPVEIVLNPLGV
HHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEEECCCC
PSRMNVGQILETHLGWAAKGIGWRIEEMLQKQTSAESLKAYLKDVYGDDEVGTFIDGMDQ
CCCCCHHHHHHHHHCHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHCCCCH
EELMLVCRRLQRGVSMASPVFEGASEDKIKSMLGKAGFHSSGQVTLFDGRSGDPFKHKVT
HHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHH
VGVMYVLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRLGEMEVWAMEAYGAAYA
HHHHHHHHHHHHHCCCHHHCCCCCHHHEECCCCCCCCCCCCCCCCCEEEEEEHHHHHHHH
LQEFLTVKSDDVSGRTRMYEAIVKGKHTLEPGLPESFNVLIKELQSLCLDVELLEGEDE
HHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCEEHEECCCCC
>Mature Secondary Structure 
AYSIANNHLLRKTFTKIKNIIDIPNLIDIQKNSYRRFLQQEGVSESRNNTGLEAVFRSV
CEECCCCHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
FPIKDFSESASLEYVSYSLSKPKYDVVECHQRGMTFAAPMKVKVRLVIWDTGKESGIRAI
CCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCEEECCCEEEEEEEEEECCCCCCHHHH
KDIKEQEVYFGEIPLMTDNGTFIINGTERVIVSQLHRSPGVFYDHDKGKTHSSGKVLYSA
HHHHHHCEEECCCEEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEE
RVIPYRGSWLDFEFDHKDILYVRIDRRRKMPATVLLKALGYSAEQLLNYYYKSEEIFLTG
EEEEECCCEEEEEECCCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHCCCEEEEEC
ETPSKSIDAELLTLQKALVDVVDPKSGEVIVKANRKFTKASIRKMVEHDIKAVPITFDSI
CCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEEEHHHH
IGRYASSDVIDPATGEVLLECNEEVTAEKFDEIKAKGVESFRLLFIDNLHITSSFRDTLL
HHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCEEEEEEEECEEEECHHHHHHH
MDKISTNDEALIEIYRRLRPGDPPTLKSSLALFENLFFNPERYDLSAVGRLKLNFKLGLK
HHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEECCE
VWPECTVLNAPCMFGAEDIASFDELFRLLLAADNRFSQYVLARLPEDFVKVLRKHEPSQP
ECCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHCCCCCH
VAEKLREQLLKELNNLVKDPDFYQKELFTGLALSQQTVALTEAIEGGVFEENRRVIEVLR
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHH
RNRMIFEDLYAPVVLTSPKNDILEIVRYLIDLKNGRGAIDDIDHLGNRRVRAVGELLENQ
HCCHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHCH
YRIGLVRMERAIKERMSLQEVENLMPHDLINSKPVSAVVKEFFGSSQLSQFMDQTNPLSE
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHCHHHHHHHHHCCCCHHH
VTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLIASLSTYARIND
HHHHHHHHHCCCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEHHHHEEECC
HGFVETPYRIVLDGKLTNEVRFFSALEEEGHAIAQANAEVDAEGRFVNDYVSARKSGEFI
CCCEECCEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHCCCCCEE
LVHRDEIELMDVAPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLLRADSPLVGTG
EEECCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHCCHHCCCCCCCCCC
MERIVAKDSGVSVIARHNGVVESVDASRIVVKIDESEVDETGTGVDIYNLIKFARSNQNT
HHHHHCCCCCCEEEEECCCCEECCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCC
CINNKPVVKVGDVVKRHDVIADGPSTDMGELALGQNIVVAFMPWGGYNFEDSILVSEKLV
CCCCCCCEEHHHHHHHCCCCCCCCCCCCHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHH
KDDRYTSIHIEEYECVARDTKLGKEEITSDIPNLGEEALKDLDESGIIRIGAEVKPGDIL
CCCCCEEEEEEHHHHHHHHHHCCHHHHHHHCCCCCHHHHHCCCCCCEEEECCCCCCCCEE
VGKITPKGETQLSPEEKLLRAIFGEKAGDVRDTSLTVPPGVEGTVIGAKVFSRKGADKDT
EEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCEEEHHHHHHCCCCCCHH
RTELIEKAEEEKLRKDEQDEIRIIRQSAEGKLHRLLIGKSLSVKLEDGEGNLILAKGKEI
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCCEEEECCCHH
TAEALKSLSINDMGAISVSDDGQTDDNVSKVIDTLNRQIELIQSVFEDKIQKLRRGDDLP
HHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PGVIKMVKVYIAIKRKLQVGDKMAGRHGNKGVVSRILPEEDMPYMEDGRPVEIVLNPLGV
HHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEEECCCC
PSRMNVGQILETHLGWAAKGIGWRIEEMLQKQTSAESLKAYLKDVYGDDEVGTFIDGMDQ
CCCCCHHHHHHHHHCHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHCCCCH
EELMLVCRRLQRGVSMASPVFEGASEDKIKSMLGKAGFHSSGQVTLFDGRSGDPFKHKVT
HHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHH
VGVMYVLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRLGEMEVWAMEAYGAAYA
HHHHHHHHHHHHHCCCHHHCCCCCHHHEECCCCCCCCCCCCCCCCCEEEEEEHHHHHHHH
LQEFLTVKSDDVSGRTRMYEAIVKGKHTLEPGLPESFNVLIKELQSLCLDVELLEGEDE
HHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCEEHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA