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The map label for this gene is coaX

Identifier: 118579094

GI number: 118579094

Start: 693272

End: 694036

Strand: Direct

Name: coaX

Synonym: Ppro_0655

Alternate gene names: 118579094

Gene position: 693272-694036 (Clockwise)

Preceding gene: 118579093

Following gene: 118579095

Centisome position: 17.3

GC content: 62.22

Gene sequence:

>765_bases
ATGCTTCTGGTAATAGACGTCGGCAACAGCAATATCGTTCTGGGTATCTGCGACGGGACGCAGCTGGTCCGCAACTGGCG
GATCTCCACCGACAAATCGCGCACGTCGGACGAGTACGGGGTTCTGCTGCACAGCCTGTTTGCCTCGGCCGGACTGGGTT
TCGATACCGTCGATGCCGCCATCATCTCCTCCGTCGTGCCGCCGCTCACCGGCGTGATGGAGGCCATCTGCCGGGATTTC
TTTCACCTGACCCCCTTCGTGGTGGGGCCGGGCATCAAGACCGGCATGCCCATCCTGTACGACAACCCCCGCGAGGTGGG
GGCGGACCGCATCGTCAACGCGGTGGCCGGCTACGAGAAGCACAAATGCTCGCTGGTGATCGTCGATTTCGGCACGGCGA
CCACCTTCGACTATGTCAATGCCAGGGGTGAGTACTGCGGCGGCGCCATTGCCCCGGGACTGGCCATCTCCCTGGAGGCG
CTGTTCCAGCGAGCCAGCAAACTGCCGCGGGTGGACATCGCCCGGCCGCCCCAGATCATTGCCCGCAACACGGTAAACTC
AATGCAGGCCGGCATATTCTACGGCTATGTGGGGCTGGTAGACGAGATCGTCAACCGCATCGTGGCCGAGAGCAAAGACA
CTCCCCGGGTGATCGCCACCGGCGGCCTGGCCAAGCTGATTGCCCCCGAATCCCGCACCATCGTCGAGGTTGATGACTTT
CTGACCCTGGACGGGTTGAAAATACTGTACGAGAGGAACCGCTAA

Upstream 100 bases:

>100_bases
GGCATGTTCGCCGGCATTGATGGTTCCGGCGCCCTGCTGGTGAGCGGGGCGGATGGGGCGATCAGTAAAATTCTCAGTGG
AGACGTGAGGGTACTTTGAC

Downstream 100 bases:

>100_bases
GGATTACATAGAGCGACGTGCGTCGTGATGAATGAAGACGGTTGCGATGGCATGCCGTTCCAGTAGTGGAAACGTTGGTG
TACCGATTTTATTTCATTCC

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MLLVIDVGNSNIVLGICDGTQLVRNWRISTDKSRTSDEYGVLLHSLFASAGLGFDTVDAAIISSVVPPLTGVMEAICRDF
FHLTPFVVGPGIKTGMPILYDNPREVGADRIVNAVAGYEKHKCSLVIVDFGTATTFDYVNARGEYCGGAIAPGLAISLEA
LFQRASKLPRVDIARPPQIIARNTVNSMQAGIFYGYVGLVDEIVNRIVAESKDTPRVIATGGLAKLIAPESRTIVEVDDF
LTLDGLKILYERNR

Sequences:

>Translated_254_residues
MLLVIDVGNSNIVLGICDGTQLVRNWRISTDKSRTSDEYGVLLHSLFASAGLGFDTVDAAIISSVVPPLTGVMEAICRDF
FHLTPFVVGPGIKTGMPILYDNPREVGADRIVNAVAGYEKHKCSLVIVDFGTATTFDYVNARGEYCGGAIAPGLAISLEA
LFQRASKLPRVDIARPPQIIARNTVNSMQAGIFYGYVGLVDEIVNRIVAESKDTPRVIATGGLAKLIAPESRTIVEVDDF
LTLDGLKILYERNR
>Mature_254_residues
MLLVIDVGNSNIVLGICDGTQLVRNWRISTDKSRTSDEYGVLLHSLFASAGLGFDTVDAAIISSVVPPLTGVMEAICRDF
FHLTPFVVGPGIKTGMPILYDNPREVGADRIVNAVAGYEKHKCSLVIVDFGTATTFDYVNARGEYCGGAIAPGLAISLEA
LFQRASKLPRVDIARPPQIIARNTVNSMQAGIFYGYVGLVDEIVNRIVAESKDTPRVIATGGLAKLIAPESRTIVEVDDF
LTLDGLKILYERNR

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_PELPD (A1ALR6)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_900344.1
- ProteinModelPortal:   A1ALR6
- SMR:   A1ALR6
- STRING:   A1ALR6
- GeneID:   4571832
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_0655
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- ProtClustDB:   PRK13321
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 27445; Mature: 27445

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: ACT_SITE 109-109 BINDING 100-100 BINDING 132-132 BINDING 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLVIDVGNSNIVLGICDGTQLVRNWRISTDKSRTSDEYGVLLHSLFASAGLGFDTVDAA
CEEEEEECCCEEEEEEECCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
IISSVVPPLTGVMEAICRDFFHLTPFVVGPGIKTGMPILYDNPREVGADRIVNAVAGYEK
HHHHHCCHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCC
HKCSLVIVDFGTATTFDYVNARGEYCGGAIAPGLAISLEALFQRASKLPRVDIARPPQII
CCEEEEEEECCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHH
ARNTVNSMQAGIFYGYVGLVDEIVNRIVAESKDTPRVIATGGLAKLIAPESRTIVEVDDF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHCCCCCCEEEEECCE
LTLDGLKILYERNR
EECCCEEEEEECCC
>Mature Secondary Structure
MLLVIDVGNSNIVLGICDGTQLVRNWRISTDKSRTSDEYGVLLHSLFASAGLGFDTVDAA
CEEEEEECCCEEEEEEECCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
IISSVVPPLTGVMEAICRDFFHLTPFVVGPGIKTGMPILYDNPREVGADRIVNAVAGYEK
HHHHHCCHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCC
HKCSLVIVDFGTATTFDYVNARGEYCGGAIAPGLAISLEALFQRASKLPRVDIARPPQII
CCEEEEEEECCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHH
ARNTVNSMQAGIFYGYVGLVDEIVNRIVAESKDTPRVIATGGLAKLIAPESRTIVEVDDF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHCCCCCCEEEEECCE
LTLDGLKILYERNR
EECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA