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The map label for this gene is cat1 [H]

Identifier: 118578728

GI number: 118578728

Start: 282988

End: 284583

Strand: Reverse

Name: cat1 [H]

Synonym: Ppro_0286

Alternate gene names: 118578728

Gene position: 284583-282988 (Counterclockwise)

Preceding gene: 118578729

Following gene: 118578724

Centisome position: 7.1

GC content: 60.84

Gene sequence:

>1596_bases
ATGTCTGAGTACGGCACGCTGCAGGACCGTGTACGCTGCAAGTCCCTTTTGAGCAAGCTTGTTCCGGTTGAGGAGACCTT
CCAGTACTTGAAGGACGGCATGAATCTCGGCTGGTCCGGATTTACCCCGGCCGGTTATCCCAAGGCGATCCCCATCGCGT
TCGCGGACCACGTGGAGAAGAACAATCTCCAGGGCAAGATGAGATTCAACCTGTTCATCGGCGCCTCGGTCGGAGCTGAG
ACCGAAGACCGCTGGGCATCCCTCAACATGATCGACCGCCGCTGGCCGTACCAGACCGGCAAGAACATCGCCGCCGGCAT
CAACGAAGGCCGCATCCGCATGGGCGACAAGCATCTCTCCATGTTCGCCCAGGACCTGGGCTACGGCTTCTACACCAAGG
ACTCCCCCACCGGCAGGCTTGACCTGGCCCTGATCGAAGTCAGCGCCATCACCGAAGAGGGTGGCCTGATCCTGGGCACA
TCCTGCGGCGCCGTTCCCGAAATCCTGATGATGGCCGACAAGATCATCCTGGAAGTCAACACCGCCATGCCCTCCCTGGA
AGGGATCCACGACATCGTGGTCAACAAGAATCCCCCCAACCGGGAAGTACTCAACATCACCAAGGCCAACTCCCGCATCG
GCACCACCTATGTTCCCTGCGACCTGAGCAAAGTTGTCGCCATCGTCGAATCCAAACACCCTGACAAGGGTCGCGCCTTC
GCCGACTCGGACGAGTCCTCCGATGCCATCGCCGCTCACCTGATGGATTTCTTCAGCAACGAAGTCAAAATGGGTCGCCT
GCCCAAGAACCTGCTGCCGATCCAGTCGGGTGTCGGTTCCATCGCCAACGCCGTCGTGGGCGGCCTGGCCAAGGGCCCCT
TCTACAACCTGAGCGTGTACACCGAAGTGCTCCAGGACTCCATGCTCGACCTGTTCGACTCCGGCCGTCTCGACTGCGCC
TCCTCCTGCTCCCTGTCCCTGTCGGAGAAGGAAGGCTTCCCGCGCTTCCTGGCCAACATGGACAAGTATTTCGACAAGAT
CACGCTGCGTCCGCTCTCCATCGCCAACCATCCGGAGCCGATCCGTCGTCTGGGCGTCATTGCCATGAACACCCCGATCG
AGATCGACATCTACTGCCACGCCAACTCCACCCTGGTGGGCGGTACCCGCATGATCAACGGCATCGGCGGTTCCGGCGAC
TTCCTGCGCAACGGCTTCCTGAAGATCATGCACACCCCGTCGTCACGTCCCTCCAAGACCGACCCGACCGGCATCACCTG
CGTGGTTCCGCACTGCCCGCACATCGACCACACCGAGCACGACCTGGACTGCGTGGTCACCGAGCAGGGTCTGGCCGACT
GCCGTGGCCTGGCTCCCAAGGATCGCGCCAAGCTGATCATTGAGAAGTGCGCCCACCCTGATTACAAGCCAATCCTGACC
GAGTACCTGGAGATCGCCACCGCCGACTGCTTCAAGCGCAAGGTGGGTCACCAGCCTCAGCTGTGGGACCGCGCCTTCAA
GATGCAGCTTAACCTGGCCCAGAACGGCACCATGAAGATCAAGAACTGGGACATGAAGATCGACCTCTGCGAATAG

Upstream 100 bases:

>100_bases
CAACCACCTAATATAGCTCGCTTTTTCTCTATATTGCCCATTACCATCGTTCAGTACGGCATCTGTCCCTGGACACATAA
CATTCATCAGGAGGAAGAAA

Downstream 100 bases:

>100_bases
TCGTTATTTTTCGCGACCAGCACGAAGAAGCCCTGCCGGGAAACCGGCGGGGCTTCTTTCGTTCAGGGGCGGGATTTCGC
CCCGCAGACAGCGGCACAGA

Product: acetyl-CoA hydrolase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MSEYGTLQDRVRCKSLLSKLVPVEETFQYLKDGMNLGWSGFTPAGYPKAIPIAFADHVEKNNLQGKMRFNLFIGASVGAE
TEDRWASLNMIDRRWPYQTGKNIAAGINEGRIRMGDKHLSMFAQDLGYGFYTKDSPTGRLDLALIEVSAITEEGGLILGT
SCGAVPEILMMADKIILEVNTAMPSLEGIHDIVVNKNPPNREVLNITKANSRIGTTYVPCDLSKVVAIVESKHPDKGRAF
ADSDESSDAIAAHLMDFFSNEVKMGRLPKNLLPIQSGVGSIANAVVGGLAKGPFYNLSVYTEVLQDSMLDLFDSGRLDCA
SSCSLSLSEKEGFPRFLANMDKYFDKITLRPLSIANHPEPIRRLGVIAMNTPIEIDIYCHANSTLVGGTRMINGIGGSGD
FLRNGFLKIMHTPSSRPSKTDPTGITCVVPHCPHIDHTEHDLDCVVTEQGLADCRGLAPKDRAKLIIEKCAHPDYKPILT
EYLEIATADCFKRKVGHQPQLWDRAFKMQLNLAQNGTMKIKNWDMKIDLCE

Sequences:

>Translated_531_residues
MSEYGTLQDRVRCKSLLSKLVPVEETFQYLKDGMNLGWSGFTPAGYPKAIPIAFADHVEKNNLQGKMRFNLFIGASVGAE
TEDRWASLNMIDRRWPYQTGKNIAAGINEGRIRMGDKHLSMFAQDLGYGFYTKDSPTGRLDLALIEVSAITEEGGLILGT
SCGAVPEILMMADKIILEVNTAMPSLEGIHDIVVNKNPPNREVLNITKANSRIGTTYVPCDLSKVVAIVESKHPDKGRAF
ADSDESSDAIAAHLMDFFSNEVKMGRLPKNLLPIQSGVGSIANAVVGGLAKGPFYNLSVYTEVLQDSMLDLFDSGRLDCA
SSCSLSLSEKEGFPRFLANMDKYFDKITLRPLSIANHPEPIRRLGVIAMNTPIEIDIYCHANSTLVGGTRMINGIGGSGD
FLRNGFLKIMHTPSSRPSKTDPTGITCVVPHCPHIDHTEHDLDCVVTEQGLADCRGLAPKDRAKLIIEKCAHPDYKPILT
EYLEIATADCFKRKVGHQPQLWDRAFKMQLNLAQNGTMKIKNWDMKIDLCE
>Mature_530_residues
SEYGTLQDRVRCKSLLSKLVPVEETFQYLKDGMNLGWSGFTPAGYPKAIPIAFADHVEKNNLQGKMRFNLFIGASVGAET
EDRWASLNMIDRRWPYQTGKNIAAGINEGRIRMGDKHLSMFAQDLGYGFYTKDSPTGRLDLALIEVSAITEEGGLILGTS
CGAVPEILMMADKIILEVNTAMPSLEGIHDIVVNKNPPNREVLNITKANSRIGTTYVPCDLSKVVAIVESKHPDKGRAFA
DSDESSDAIAAHLMDFFSNEVKMGRLPKNLLPIQSGVGSIANAVVGGLAKGPFYNLSVYTEVLQDSMLDLFDSGRLDCAS
SCSLSLSEKEGFPRFLANMDKYFDKITLRPLSIANHPEPIRRLGVIAMNTPIEIDIYCHANSTLVGGTRMINGIGGSGDF
LRNGFLKIMHTPSSRPSKTDPTGITCVVPHCPHIDHTEHDLDCVVTEQGLADCRGLAPKDRAKLIIEKCAHPDYKPILTE
YLEIATADCFKRKVGHQPQLWDRAFKMQLNLAQNGTMKIKNWDMKIDLCE

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=498, Percent_Identity=39.7590361445783, Blast_Score=357, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6319456, Length=525, Percent_Identity=55.2380952380952, Blast_Score=585, Evalue=1e-168,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 58526; Mature: 58395

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEYGTLQDRVRCKSLLSKLVPVEETFQYLKDGMNLGWSGFTPAGYPKAIPIAFADHVEK
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHC
NNLQGKMRFNLFIGASVGAETEDRWASLNMIDRRWPYQTGKNIAAGINEGRIRMGDKHLS
CCCCEEEEEEEEEECCCCCCCHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCEEECHHHHH
MFAQDLGYGFYTKDSPTGRLDLALIEVSAITEEGGLILGTSCGAVPEILMMADKIILEVN
HHHHHHCCCEEECCCCCCCEEEEEEEEEEEECCCCEEEECCCCHHHHHHHHHHHHEEEEC
TAMPSLEGIHDIVVNKNPPNREVLNITKANSRIGTTYVPCDLSKVVAIVESKHPDKGRAF
CCCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCEEECCCHHHHHHHHHCCCCCCCCCC
ADSDESSDAIAAHLMDFFSNEVKMGRLPKNLLPIQSGVGSIANAVVGGLAKGPFYNLSVY
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHH
TEVLQDSMLDLFDSGRLDCASSCSLSLSEKEGFPRFLANMDKYFDKITLRPLSIANHPEP
HHHHHHHHHHHHCCCCCCCCCCCCEEEHHHCCCHHHHHHHHHHHHHEECCEEECCCCCHH
IRRLGVIAMNTPIEIDIYCHANSTLVGGTRMINGIGGSGDFLRNGFLKIMHTPSSRPSKT
HHHHCEEEECCCEEEEEEEECCCEEECCHHEEECCCCCCHHHHCCCEEEEECCCCCCCCC
DPTGITCVVPHCPHIDHTEHDLDCVVTEQGLADCRGLAPKDRAKLIIEKCAHPDYKPILT
CCCCEEEEECCCCCCCCCCCCCEEEEECCCHHHHHCCCCCHHHHHHHHHHCCCCCHHHHH
EYLEIATADCFKRKVGHQPQLWDRAFKMQLNLAQNGTMKIKNWDMKIDLCE
HHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCEEEEEECCEEEEECC
>Mature Secondary Structure 
SEYGTLQDRVRCKSLLSKLVPVEETFQYLKDGMNLGWSGFTPAGYPKAIPIAFADHVEK
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHC
NNLQGKMRFNLFIGASVGAETEDRWASLNMIDRRWPYQTGKNIAAGINEGRIRMGDKHLS
CCCCEEEEEEEEEECCCCCCCHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCEEECHHHHH
MFAQDLGYGFYTKDSPTGRLDLALIEVSAITEEGGLILGTSCGAVPEILMMADKIILEVN
HHHHHHCCCEEECCCCCCCEEEEEEEEEEEECCCCEEEECCCCHHHHHHHHHHHHEEEEC
TAMPSLEGIHDIVVNKNPPNREVLNITKANSRIGTTYVPCDLSKVVAIVESKHPDKGRAF
CCCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCEEECCCHHHHHHHHHCCCCCCCCCC
ADSDESSDAIAAHLMDFFSNEVKMGRLPKNLLPIQSGVGSIANAVVGGLAKGPFYNLSVY
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHH
TEVLQDSMLDLFDSGRLDCASSCSLSLSEKEGFPRFLANMDKYFDKITLRPLSIANHPEP
HHHHHHHHHHHHCCCCCCCCCCCCEEEHHHCCCHHHHHHHHHHHHHEECCEEECCCCCHH
IRRLGVIAMNTPIEIDIYCHANSTLVGGTRMINGIGGSGDFLRNGFLKIMHTPSSRPSKT
HHHHCEEEECCCEEEEEEEECCCEEECCHHEEECCCCCCHHHHCCCEEEEECCCCCCCCC
DPTGITCVVPHCPHIDHTEHDLDCVVTEQGLADCRGLAPKDRAKLIIEKCAHPDYKPILT
CCCCEEEEECCCCCCCCCCCCCEEEEECCCHHHHHCCCCCHHHHHHHHHHCCCCCHHHHH
EYLEIATADCFKRKVGHQPQLWDRAFKMQLNLAQNGTMKIKNWDMKIDLCE
HHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCEEEEEECCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]