Click here to switch to the map view.

The map label for this gene is dinB [H]

Identifier: 118578634

GI number: 118578634

Start: 191641

End: 192873

Strand: Reverse

Name: dinB [H]

Synonym: Ppro_0190

Alternate gene names: 118578634

Gene position: 192873-191641 (Counterclockwise)

Preceding gene: 118578635

Following gene: 118578633

Centisome position: 4.81

GC content: 54.58

Gene sequence:

>1233_bases
ATGGGCAGCCGGGTTGTCATGCATCTCGACATGAACAGTTTTTTCGCCTCCGTCGAGCAGTCCGCCAACCCTGACCTCAA
GGGGAAGCCGGTTGTTGTCACCGGTTCACAGCAGAGAACCGTGATCCTCACCGCCTCCTACGAGGCCCGGAAATTCGGGA
TCAAGACCGGCATGATGCTGCACGAGGCCAGAAGGCTGTGCCGTGACGTCATCATGGTACCGGCGGATAACCGGAAATAT
ATCCATACATCAGCACAGATCATGAAAATGATGCTGGACTACACCCCTCTGGTCGAGGTTTTTTCGATTGACGAGGCGTT
CATGGATGTCACCCATTCCATGTCGCTGTTCACTAGCGCCGAGAATATCGCCTATCTTCTCAAGGCCCGCATCCGGCACC
AATTTGATATTACCTGTTCCATCGGCATTGCCCCGAATAAACTCCTCGCGAAACTTGCTTCGGAAATGAAAAAACCAGAC
GGTTTGACAGTTATCGCACCGGAAAACGTCAGCCGGGTGCTGGAGACCATGCCGATCAAGGAGCTTTGCGGCATCGGTAA
GAAGATGGAGCGGCATCTCAACATGATGGGAATCTATACGTGTGGTGAGTTGGGGCGTTGTGATGAAGGGCGTCTGACCA
GGAAATTCGGCATTGTCGGCAGCCGGCTGAAGCAGATGGGGCTTGGCATCGACAACTCACCGGTCATACCGGCTGAAGAC
GCCGATGCGGTGAAGTCGGTTGGGCATTCCATGACACTTAAAAAGGATATCAGCAGTCGGAGCGAGATTCTGCGATATCT
GTTGCAGCTCTCGGAGATGGTAGGGAGGCGGGCCCGCCGCTACGGAGTGGCAGGGAAAACGGTCCACCTGACCATCCGCT
ACGCTGACTTCAGTACCTTCGGCAAGCAGGGCACCCTGTCTCAGCACGTCAACCAGAGCGATGAGATCTACCAGGGCGTC
GTGAAGATCCTGGATAGCATCGAACTGGAACAGCCTGTACGCCTGCTGGGGGTAAGGATCACCAACCTCTGTTACCAGCG
CGAACAGTTGCCCCTTTTCGAAGACGAGCGCCGGAAGGCTTTTATGGTCAACGCCATGGATACGGTCAATGACAAGTTCG
GCGATTTTACCGTGACGTTCGGAAGTCTTTTGGGCAACAATGATGAGAAGGGTTCACACGTAATCTCGCCGGCTTGGAAG
CCGGAGGGAATCAGGAACGTGCAAGTGAGGTAA

Upstream 100 bases:

>100_bases
CACTCCTGCATTTCGCCGTGACTGACGGGGATGCTCTCTATGACCTGGTCTACAATACGTTGGACCAGAGCTGGCTCCTG
AACGGCATCGAGGTGACGTG

Downstream 100 bases:

>100_bases
GCCATGTGCGGTCGTCTGGTCATTGATCTGTCACCGGAAATGATCACTGAGATTTACGGGATCATCAGGGACATCGAGCG
CGAACTAAATCCGAGATATA

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MGSRVVMHLDMNSFFASVEQSANPDLKGKPVVVTGSQQRTVILTASYEARKFGIKTGMMLHEARRLCRDVIMVPADNRKY
IHTSAQIMKMMLDYTPLVEVFSIDEAFMDVTHSMSLFTSAENIAYLLKARIRHQFDITCSIGIAPNKLLAKLASEMKKPD
GLTVIAPENVSRVLETMPIKELCGIGKKMERHLNMMGIYTCGELGRCDEGRLTRKFGIVGSRLKQMGLGIDNSPVIPAED
ADAVKSVGHSMTLKKDISSRSEILRYLLQLSEMVGRRARRYGVAGKTVHLTIRYADFSTFGKQGTLSQHVNQSDEIYQGV
VKILDSIELEQPVRLLGVRITNLCYQREQLPLFEDERRKAFMVNAMDTVNDKFGDFTVTFGSLLGNNDEKGSHVISPAWK
PEGIRNVQVR

Sequences:

>Translated_410_residues
MGSRVVMHLDMNSFFASVEQSANPDLKGKPVVVTGSQQRTVILTASYEARKFGIKTGMMLHEARRLCRDVIMVPADNRKY
IHTSAQIMKMMLDYTPLVEVFSIDEAFMDVTHSMSLFTSAENIAYLLKARIRHQFDITCSIGIAPNKLLAKLASEMKKPD
GLTVIAPENVSRVLETMPIKELCGIGKKMERHLNMMGIYTCGELGRCDEGRLTRKFGIVGSRLKQMGLGIDNSPVIPAED
ADAVKSVGHSMTLKKDISSRSEILRYLLQLSEMVGRRARRYGVAGKTVHLTIRYADFSTFGKQGTLSQHVNQSDEIYQGV
VKILDSIELEQPVRLLGVRITNLCYQREQLPLFEDERRKAFMVNAMDTVNDKFGDFTVTFGSLLGNNDEKGSHVISPAWK
PEGIRNVQVR
>Mature_409_residues
GSRVVMHLDMNSFFASVEQSANPDLKGKPVVVTGSQQRTVILTASYEARKFGIKTGMMLHEARRLCRDVIMVPADNRKYI
HTSAQIMKMMLDYTPLVEVFSIDEAFMDVTHSMSLFTSAENIAYLLKARIRHQFDITCSIGIAPNKLLAKLASEMKKPDG
LTVIAPENVSRVLETMPIKELCGIGKKMERHLNMMGIYTCGELGRCDEGRLTRKFGIVGSRLKQMGLGIDNSPVIPAEDA
DAVKSVGHSMTLKKDISSRSEILRYLLQLSEMVGRRARRYGVAGKTVHLTIRYADFSTFGKQGTLSQHVNQSDEIYQGVV
KILDSIELEQPVRLLGVRITNLCYQREQLPLFEDERRKAFMVNAMDTVNDKFGDFTVTFGSLLGNNDEKGSHVISPAWKP
EGIRNVQVR

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=408, Percent_Identity=27.4509803921569, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI7706681, Length=409, Percent_Identity=27.3838630806846, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI154350220, Length=352, Percent_Identity=28.6931818181818, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI7705344, Length=112, Percent_Identity=37.5, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI5729982, Length=120, Percent_Identity=37.5, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1786425, Length=355, Percent_Identity=35.4929577464789, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1787432, Length=392, Percent_Identity=25.765306122449, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI193205700, Length=423, Percent_Identity=26.0047281323877, Blast_Score=121, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI115534089, Length=392, Percent_Identity=27.0408163265306, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17537959, Length=311, Percent_Identity=26.6881028938907, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI193205702, Length=363, Percent_Identity=24.2424242424242, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355641, Length=316, Percent_Identity=29.1139240506329, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24644984, Length=316, Percent_Identity=29.1139240506329, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI19923006, Length=342, Percent_Identity=26.0233918128655, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24668444, Length=121, Percent_Identity=30.5785123966942, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 45956; Mature: 45825

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS50173 UMUC ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSRVVMHLDMNSFFASVEQSANPDLKGKPVVVTGSQQRTVILTASYEARKFGIKTGMML
CCCEEEEEECHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEEECCHHHHHCCHHHHHH
HEARRLCRDVIMVPADNRKYIHTSAQIMKMMLDYTPLVEVFSIDEAFMDVTHSMSLFTSA
HHHHHHHHHHEECCCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ENIAYLLKARIRHQFDITCSIGIAPNKLLAKLASEMKKPDGLTVIAPENVSRVLETMPIK
HHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHCCHH
ELCGIGKKMERHLNMMGIYTCGELGRCDEGRLTRKFGIVGSRLKQMGLGIDNSPVIPAED
HHHCCHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
ADAVKSVGHSMTLKKDISSRSEILRYLLQLSEMVGRRARRYGVAGKTVHLTIRYADFSTF
HHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECHHHC
GKQGTLSQHVNQSDEIYQGVVKILDSIELEQPVRLLGVRITNLCYQREQLPLFEDERRKA
CCCCCHHHHCCCHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCE
FMVNAMDTVNDKFGDFTVTFGSLLGNNDEKGSHVISPAWKPEGIRNVQVR
EEEEHHHHHCCCCCCEEEEEHHHHCCCCCCCCEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
GSRVVMHLDMNSFFASVEQSANPDLKGKPVVVTGSQQRTVILTASYEARKFGIKTGMML
CCEEEEEECHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEEECCHHHHHCCHHHHHH
HEARRLCRDVIMVPADNRKYIHTSAQIMKMMLDYTPLVEVFSIDEAFMDVTHSMSLFTSA
HHHHHHHHHHEECCCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ENIAYLLKARIRHQFDITCSIGIAPNKLLAKLASEMKKPDGLTVIAPENVSRVLETMPIK
HHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHCCHH
ELCGIGKKMERHLNMMGIYTCGELGRCDEGRLTRKFGIVGSRLKQMGLGIDNSPVIPAED
HHHCCHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
ADAVKSVGHSMTLKKDISSRSEILRYLLQLSEMVGRRARRYGVAGKTVHLTIRYADFSTF
HHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECHHHC
GKQGTLSQHVNQSDEIYQGVVKILDSIELEQPVRLLGVRITNLCYQREQLPLFEDERRKA
CCCCCHHHHCCCHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCE
FMVNAMDTVNDKFGDFTVTFGSLLGNNDEKGSHVISPAWKPEGIRNVQVR
EEEEHHHHHCCCCCCEEEEEHHHHCCCCCCCCEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA