Click here to switch to the map view.

The map label for this gene is arnA [H]

Identifier: 118578503

GI number: 118578503

Start: 62697

End: 63632

Strand: Direct

Name: arnA [H]

Synonym: Ppro_0055

Alternate gene names: 118578503

Gene position: 62697-63632 (Clockwise)

Preceding gene: 118578502

Following gene: 118578504

Centisome position: 1.56

GC content: 65.06

Gene sequence:

>936_bases
GTGAGGATTGCGGTTCTGTGCAGCGGCAGCGTACTGCAACCGGTTCTGGAGGCGCTCTACAGCCAGGGGTTGCTGGCCGG
CGTGGCCGTGCCAGCGGCACCGGCAGTCGAAGATCCGAACCTGGCGCTGGAGACTGTGCTGCGTCAGGCCCGGGTATCCT
GCCTGCGGGTGGATAACGGCGACCTGACCGGGCAGATGGCTCCCTGGTTGCGCTCGCTTGCGGCGGATGCGCTCTGCTGC
ATGGGGTTTCCCCGCAAACTTCCGGCTGACCTCCTTACCATGCCGCCACTGGGCTGTTATAACTTCCATGGCGGCCCTCT
CCCCCAGTATCGCGGACCGGACCCGGTTTTCTGGCAGATCAGAAACCGGGAGGTGGCCGGTGCCATCACCGTCCACCGCA
TGACTCCCCGGATCGACTCCGGTGCCATCGCCCATGAGGCGCACCTGCCGATAGGGACGGATGATACCTATGGTCTCTGG
ATGCAGAGGCTGGGTGGAGCGCTTCCCCGGGTGATGATCGAATTCGTCCAGCAGTTGGCGATCCATGGCGCGGCAGTGCC
GTTACGGGAACAGGATCCGGAAACGGGCCGCTATTTCCCCCGCCCCACCGATGCGGACCGCACCATCGACTGGTCATGGG
GCGCATCCGCCATCGATGCCCTGGTGCGGGCCTGCAACCCGGTCTACGGCGGCGCCCTGACCACACTGCACGGGGTGCCG
GTGCGTTTGCTGGAGGTTTCTCCCCTGCCTGCCCAGGCAGGGGGGGAGAGTACCTCCGGCACGGTTGTTACGGCGGATGC
TGCGGAGGGGCTGCGCGTTGCCTGCGGTACAGGCGAATTGCTCCGGCTGGAGCTGTTGTACGGTATGGAAGGTTTTTTCA
GCGGCCCTCGTCTGGCGCGTATTTTTGGTTTGAAACCGGGGCAGCGGTTGGCATGA

Upstream 100 bases:

>100_bases
GCGACCACGCCCGCCAGGCCGTATACCTGCAACCGCGTCAGAAAGTCTTCTTCAAAGACACCCCGGTGTGGTTGGCCCCG
GACTATCGGGGGCTGTTATC

Downstream 100 bases:

>100_bases
TCACCGACACGGCGATGGCTGCTCTTTTGCAATGTTGTAGACACTATTCGTCCTAAGGTTCTTACATTCCCATGACCAAC
CAGTATCGAGTCTTTGGCCT

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: UDP-4-amino-4-deoxy-L-arabinose formyltransferase; ArnAFT; UDP-L-Ara4N formyltransferase; UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating; ArnADH; UDP-GlcUA decarboxylase; UDP-glucuronic acid dehydrogenase [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MRIAVLCSGSVLQPVLEALYSQGLLAGVAVPAAPAVEDPNLALETVLRQARVSCLRVDNGDLTGQMAPWLRSLAADALCC
MGFPRKLPADLLTMPPLGCYNFHGGPLPQYRGPDPVFWQIRNREVAGAITVHRMTPRIDSGAIAHEAHLPIGTDDTYGLW
MQRLGGALPRVMIEFVQQLAIHGAAVPLREQDPETGRYFPRPTDADRTIDWSWGASAIDALVRACNPVYGGALTTLHGVP
VRLLEVSPLPAQAGGESTSGTVVTADAAEGLRVACGTGELLRLELLYGMEGFFSGPRLARIFGLKPGQRLA

Sequences:

>Translated_311_residues
MRIAVLCSGSVLQPVLEALYSQGLLAGVAVPAAPAVEDPNLALETVLRQARVSCLRVDNGDLTGQMAPWLRSLAADALCC
MGFPRKLPADLLTMPPLGCYNFHGGPLPQYRGPDPVFWQIRNREVAGAITVHRMTPRIDSGAIAHEAHLPIGTDDTYGLW
MQRLGGALPRVMIEFVQQLAIHGAAVPLREQDPETGRYFPRPTDADRTIDWSWGASAIDALVRACNPVYGGALTTLHGVP
VRLLEVSPLPAQAGGESTSGTVVTADAAEGLRVACGTGELLRLELLYGMEGFFSGPRLARIFGLKPGQRLA
>Mature_311_residues
MRIAVLCSGSVLQPVLEALYSQGLLAGVAVPAAPAVEDPNLALETVLRQARVSCLRVDNGDLTGQMAPWLRSLAADALCC
MGFPRKLPADLLTMPPLGCYNFHGGPLPQYRGPDPVFWQIRNREVAGAITVHRMTPRIDSGAIAHEAHLPIGTDDTYGLW
MQRLGGALPRVMIEFVQQLAIHGAAVPLREQDPETGRYFPRPTDADRTIDWSWGASAIDALVRACNPVYGGALTTLHGVP
VRLLEVSPLPAQAGGESTSGTVVTADAAEGLRVACGTGELLRLELLYGMEGFFSGPRLARIFGLKPGQRLA

Specific function: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabin

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the sugar epimerase family. UDP-glucuronic acid decarboxylase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789683, Length=241, Percent_Identity=29.4605809128631, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788589, Length=242, Percent_Identity=28.099173553719, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021168
- InterPro:   IPR001509
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase; PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.13; =1.1.1.305 [H]

Molecular weight: Translated: 33262; Mature: 33262

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIAVLCSGSVLQPVLEALYSQGLLAGVAVPAAPAVEDPNLALETVLRQARVSCLRVDNG
CEEEEEECCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCC
DLTGQMAPWLRSLAADALCCMGFPRKLPADLLTMPPLGCYNFHGGPLPQYRGPDPVFWQI
CCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEE
RNREVAGAITVHRMTPRIDSGAIAHEAHLPIGTDDTYGLWMQRLGGALPRVMIEFVQQLA
CCCEEEEEEEEEEECCCCCCCCCEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHH
IHGAAVPLREQDPETGRYFPRPTDADRTIDWSWGASAIDALVRACNPVYGGALTTLHGVP
HCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCHHHHHCCCC
VRLLEVSPLPAQAGGESTSGTVVTADAAEGLRVACGTGELLRLELLYGMEGFFSGPRLAR
EEEEEECCCCCCCCCCCCCCEEEEECCCCCCEEEECCCCEEEHHHHHCHHHHCCCCCEEH
IFGLKPGQRLA
EECCCCCCCCC
>Mature Secondary Structure
MRIAVLCSGSVLQPVLEALYSQGLLAGVAVPAAPAVEDPNLALETVLRQARVSCLRVDNG
CEEEEEECCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCC
DLTGQMAPWLRSLAADALCCMGFPRKLPADLLTMPPLGCYNFHGGPLPQYRGPDPVFWQI
CCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEE
RNREVAGAITVHRMTPRIDSGAIAHEAHLPIGTDDTYGLWMQRLGGALPRVMIEFVQQLA
CCCEEEEEEEEEEECCCCCCCCCEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHH
IHGAAVPLREQDPETGRYFPRPTDADRTIDWSWGASAIDALVRACNPVYGGALTTLHGVP
HCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCHHHHHCCCC
VRLLEVSPLPAQAGGESTSGTVVTADAAEGLRVACGTGELLRLELLYGMEGFFSGPRLAR
EEEEEECCCCCCCCCCCCCCEEEEECCCCCCEEEECCCCEEEHHHHHCHHHHCCCCCEEH
IFGLKPGQRLA
EECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]