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The map label for this gene is 118578481

Identifier: 118578481

GI number: 118578481

Start: 38130

End: 39629

Strand: Direct

Name: 118578481

Synonym: Ppro_0033

Alternate gene names: NA

Gene position: 38130-39629 (Clockwise)

Preceding gene: 118578471

Following gene: 118578482

Centisome position: 0.95

GC content: 61.2

Gene sequence:

>1500_bases
ATGGATAAGATCATCGACATAACCGAACTTGCCCTGCGGGATGCTCACCAGAGCCTCATCGCCACCCGTCTTGGTATCGA
GGACATGACCGGCATCTGTGAAGAGCTTGACAACGCCGGGTACTGGTCAATCGAATGCTGGGGTGGAGCCACCTTCGACT
CCTGCATCCGCTACCTGAACGAGGATCCGTGGGAGCGTCTGCGCACCTTCAAGAAGCTGATGCCCAAGACCAAGCTTCAG
ATGCTGCTTCGCGGCCAGAACCTGCTTGGCTACCGCCACTACCAGGACGAAGTGGTTGAGCGTTTCGTGGACAAGTCGGC
CGAGAACGGCATGGACGTGTACCGCATCTTCGACGCCCTGAACGACCTGCGCAACCTTGAGACCTCCATCAAGGCGGTCA
AGAAAGCCGGCAAGCACGCCCAGGGCACCATCAGCTACACGGTCAGCCCGATCCACACCACCGCCCTGTTCGTGGACCAG
GCCAAGCGCCTGCAGGACATGGGCGTTGACTCCATCTGCATCAAGGACATGGCCGCCCTGATCAAGCCGCAGCCGGCCTA
TGACCTGGTCAAGGGGATCAAGGAAGCCTGCCCCGGCCTGCGCGTCCAGCTGCATGCCCACTCCACCACCGGCGTCACCC
TGGTCAGCCTGATGAAAGCCATCGAAGCCGGCGTGGACTGCGTGGACACCGCCGTCAGCTCCATGAGCTTGGGACCTGGC
CACAACCCCACCGAGAGCCTGATCGAAATGCTGGAAGGCACCGGCTACACCACCAAAGTTGACCTGGACCGGGTCCTCAA
GGCCAAACTGTACTTCTCCAAGACCCTTGGCCGCTACAAGCAGTTCCTCTCCGCCGTCACCGGCGTCGAGACCGAAATCT
TCAAGAGCCAGATCCCGGGCGGCATGCTCTCCAACCTGGAAAGCCAGCTCAACCAGCAGGGCGCCGGCGACCGCCTCACC
GAAGTTCTGGAAGAAGTACCGCGCGTTCGCAAGGACACCGGCTATGTACCGCTGGTCACCCCCAGCAGCCAGATCGTCGG
CACCCAGGCCGTCCTCAACGTCCTGATGGGCAAATACAAGGTCCTCACCGGCGAATTCGCCGACATCATGCTCGGCTACT
ACGGCGCCAGCCCCGGCGACAAGAACATGGAAATCGTTGCCAAGGCCCAGGATCATGCCAAGAAAGAGCCGATCACCTGC
CGCCCCGCCGACCTGCTCGATCCTGAATGGGCAAAACTGAGAGCTGAAGCAGAAGCACTGGAAGGCAACGACGGTAGCGA
CGAAGACGTGCTCACCTACGCCATGTTCCCCCAGGTAGCCGCCAAATTCTTCGCCACCCGCGCAGAAGGCCCGATGAACC
TGGGCAAGGACCCGGAAGAAGGCGCCGTCGACGCAGCCACCGCTGCCGAGCACCAGGGCAAGATCACCGGCCCGATCACC
TATGCCGTCACCCTGGAAGGGCAGAAACACAAGGTAGTCGTCGCCCCGTACAAAAAGTAA

Upstream 100 bases:

>100_bases
AATGGCTGGATAAAATAGCTTGACTAATTGGTTTGATTATGTTTTTTACCCAAGGTAGCAATTTAGCACCACTATTTTCA
TTGGGGAGACAGGAAACTAC

Downstream 100 bases:

>100_bases
CCTGACCACGTAATCGCTTACTTCTACATTGTAATTTCAATACAAGTGAGGAACCATGGCAATCACAATAGAGGATAGAA
TCCAGGAACTCAACGACAAG

Product: oxaloacetate decarboxylase

Products: NA

Alternate protein names: Transcarboxylase 5S subunit [H]

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MDKIIDITELALRDAHQSLIATRLGIEDMTGICEELDNAGYWSIECWGGATFDSCIRYLNEDPWERLRTFKKLMPKTKLQ
MLLRGQNLLGYRHYQDEVVERFVDKSAENGMDVYRIFDALNDLRNLETSIKAVKKAGKHAQGTISYTVSPIHTTALFVDQ
AKRLQDMGVDSICIKDMAALIKPQPAYDLVKGIKEACPGLRVQLHAHSTTGVTLVSLMKAIEAGVDCVDTAVSSMSLGPG
HNPTESLIEMLEGTGYTTKVDLDRVLKAKLYFSKTLGRYKQFLSAVTGVETEIFKSQIPGGMLSNLESQLNQQGAGDRLT
EVLEEVPRVRKDTGYVPLVTPSSQIVGTQAVLNVLMGKYKVLTGEFADIMLGYYGASPGDKNMEIVAKAQDHAKKEPITC
RPADLLDPEWAKLRAEAEALEGNDGSDEDVLTYAMFPQVAAKFFATRAEGPMNLGKDPEEGAVDAATAAEHQGKITGPIT
YAVTLEGQKHKVVVAPYKK

Sequences:

>Translated_499_residues
MDKIIDITELALRDAHQSLIATRLGIEDMTGICEELDNAGYWSIECWGGATFDSCIRYLNEDPWERLRTFKKLMPKTKLQ
MLLRGQNLLGYRHYQDEVVERFVDKSAENGMDVYRIFDALNDLRNLETSIKAVKKAGKHAQGTISYTVSPIHTTALFVDQ
AKRLQDMGVDSICIKDMAALIKPQPAYDLVKGIKEACPGLRVQLHAHSTTGVTLVSLMKAIEAGVDCVDTAVSSMSLGPG
HNPTESLIEMLEGTGYTTKVDLDRVLKAKLYFSKTLGRYKQFLSAVTGVETEIFKSQIPGGMLSNLESQLNQQGAGDRLT
EVLEEVPRVRKDTGYVPLVTPSSQIVGTQAVLNVLMGKYKVLTGEFADIMLGYYGASPGDKNMEIVAKAQDHAKKEPITC
RPADLLDPEWAKLRAEAEALEGNDGSDEDVLTYAMFPQVAAKFFATRAEGPMNLGKDPEEGAVDAATAAEHQGKITGPIT
YAVTLEGQKHKVVVAPYKK
>Mature_499_residues
MDKIIDITELALRDAHQSLIATRLGIEDMTGICEELDNAGYWSIECWGGATFDSCIRYLNEDPWERLRTFKKLMPKTKLQ
MLLRGQNLLGYRHYQDEVVERFVDKSAENGMDVYRIFDALNDLRNLETSIKAVKKAGKHAQGTISYTVSPIHTTALFVDQ
AKRLQDMGVDSICIKDMAALIKPQPAYDLVKGIKEACPGLRVQLHAHSTTGVTLVSLMKAIEAGVDCVDTAVSSMSLGPG
HNPTESLIEMLEGTGYTTKVDLDRVLKAKLYFSKTLGRYKQFLSAVTGVETEIFKSQIPGGMLSNLESQLNQQGAGDRLT
EVLEEVPRVRKDTGYVPLVTPSSQIVGTQAVLNVLMGKYKVLTGEFADIMLGYYGASPGDKNMEIVAKAQDHAKKEPITC
RPADLLDPEWAKLRAEAEALEGNDGSDEDVLTYAMFPQVAAKFFATRAEGPMNLGKDPEEGAVDAATAAEHQGKITGPIT
YAVTLEGQKHKVVVAPYKK

Specific function: The 5S subunit specifically catalyzes the transfer of the carboxyl group from biotin of the 1.3S subunit to pyruvate to form oxaloacetate and 1.3S biotin [H]

COG id: COG5016

COG function: function code C; Pyruvate/oxaloacetate carboxyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=458, Percent_Identity=33.1877729257642, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI106049295, Length=458, Percent_Identity=33.1877729257642, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI106049292, Length=458, Percent_Identity=33.1877729257642, Blast_Score=239, Evalue=4e-63,
Organism=Caenorhabditis elegans, GI17562816, Length=469, Percent_Identity=34.3283582089552, Blast_Score=251, Evalue=5e-67,
Organism=Saccharomyces cerevisiae, GI6319695, Length=457, Percent_Identity=33.2603938730853, Blast_Score=247, Evalue=3e-66,
Organism=Saccharomyces cerevisiae, GI6321376, Length=457, Percent_Identity=32.8227571115974, Blast_Score=246, Evalue=5e-66,
Organism=Drosophila melanogaster, GI24652212, Length=467, Percent_Identity=33.6188436830835, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24652210, Length=467, Percent_Identity=33.6188436830835, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24652214, Length=467, Percent_Identity=33.6188436830835, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI19921944, Length=467, Percent_Identity=33.6188436830835, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24652216, Length=467, Percent_Identity=33.6188436830835, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI281363050, Length=467, Percent_Identity=33.6188436830835, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24652224, Length=467, Percent_Identity=33.6188436830835, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24652222, Length=467, Percent_Identity=33.6188436830835, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24652220, Length=467, Percent_Identity=33.6188436830835, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24652218, Length=467, Percent_Identity=33.6188436830835, Blast_Score=234, Evalue=1e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR003379
- InterPro:   IPR000891 [H]

Pfam domain/function: PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =2.1.3.1 [H]

Molecular weight: Translated: 54812; Mature: 54812

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS50991 PYR_CT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIIDITELALRDAHQSLIATRLGIEDMTGICEELDNAGYWSIECWGGATFDSCIRYLN
CCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHC
EDPWERLRTFKKLMPKTKLQMLLRGQNLLGYRHYQDEVVERFVDKSAENGMDVYRIFDAL
CCHHHHHHHHHHHCCHHHHHHHHHCCHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
NDLRNLETSIKAVKKAGKHAQGTISYTVSPIHTTALFVDQAKRLQDMGVDSICIKDMAAL
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IKPQPAYDLVKGIKEACPGLRVQLHAHSTTGVTLVSLMKAIEAGVDCVDTAVSSMSLGPG
HCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCC
HNPTESLIEMLEGTGYTTKVDLDRVLKAKLYFSKTLGRYKQFLSAVTGVETEIFKSQIPG
CCCHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC
GMLSNLESQLNQQGAGDRLTEVLEEVPRVRKDTGYVPLVTPSSQIVGTQAVLNVLMGKYK
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHH
VLTGEFADIMLGYYGASPGDKNMEIVAKAQDHAKKEPITCRPADLLDPEWAKLRAEAEAL
HHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
EGNDGSDEDVLTYAMFPQVAAKFFATRAEGPMNLGKDPEEGAVDAATAAEHQGKITGPIT
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEE
YAVTLEGQKHKVVVAPYKK
EEEEECCCCCEEEECCCCC
>Mature Secondary Structure
MDKIIDITELALRDAHQSLIATRLGIEDMTGICEELDNAGYWSIECWGGATFDSCIRYLN
CCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHC
EDPWERLRTFKKLMPKTKLQMLLRGQNLLGYRHYQDEVVERFVDKSAENGMDVYRIFDAL
CCHHHHHHHHHHHCCHHHHHHHHHCCHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
NDLRNLETSIKAVKKAGKHAQGTISYTVSPIHTTALFVDQAKRLQDMGVDSICIKDMAAL
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IKPQPAYDLVKGIKEACPGLRVQLHAHSTTGVTLVSLMKAIEAGVDCVDTAVSSMSLGPG
HCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCC
HNPTESLIEMLEGTGYTTKVDLDRVLKAKLYFSKTLGRYKQFLSAVTGVETEIFKSQIPG
CCCHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC
GMLSNLESQLNQQGAGDRLTEVLEEVPRVRKDTGYVPLVTPSSQIVGTQAVLNVLMGKYK
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHH
VLTGEFADIMLGYYGASPGDKNMEIVAKAQDHAKKEPITCRPADLLDPEWAKLRAEAEAL
HHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
EGNDGSDEDVLTYAMFPQVAAKFFATRAEGPMNLGKDPEEGAVDAATAAEHQGKITGPIT
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEE
YAVTLEGQKHKVVVAPYKK
EEEEECCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8365490 [H]