| Definition | Pelobacter propionicus DSM 2379 chromosome, complete genome. |
|---|---|
| Accession | NC_008609 |
| Length | 4,008,000 |
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The map label for this gene is gyrA [H]
Identifier: 118578454
GI number: 118578454
Start: 6243
End: 8774
Strand: Direct
Name: gyrA [H]
Synonym: Ppro_0005
Alternate gene names: 118578454
Gene position: 6243-8774 (Clockwise)
Preceding gene: 118578453
Following gene: 118578455
Centisome position: 0.16
GC content: 60.7
Gene sequence:
>2532_bases ATGATTAACACTCCGCAGAACAAGATAGCCGTCAACATCGAAGACGAGATGAAACGTTCCTACATGGACTACGCCATGTC GGTCATCATCGGCCGCGCCCTGCCGGACGTGCGGGACGGACTCAAGCCGGTGCACCGGCGCTGTCTGTACGCCATGTACG ACATGAGCAACGACTGGAACAAGCCGTACAAGAAATCGGCCCGTGTGGTCGGTGACGTGATCGGTAAGTACCACCCCCAC GGCGACACTGCGGCCTACGATACCATCGTGCGCATGGCCCAGGACTTCTCCCTGCGCTATACCCTGGTGGATGGCCAGGG TAACTTCGGCTCCATCGACGGCGACCGGCCGGCGGCCATGCGCTACACCGAGATCCGCCTGCGCCAGCTATCCCACGAGC TTCTGGCCGATCTGGACAAGGAAACCGTGGGCATGGCCCCCAACTACAACGACGAGTTGCTGGAGCCGACGGTCCTCCCC TCAAAGTTCCCCAACCTGCTGATCAACGGCTCCACCGGCATTGCCGTGGGCATGGCCACCAACATCCCGCCCCACAACCT GGGCGAGGTGATCGACGGCATCATCGCCGTGATCAACAACCCCGATCTGGCCCATGAAGAGCTTTTGGCCCTGATACCGG GTCCCGACTTCCCCACCGGCGCCACCATCTACGGCCGCCAGGGGATCCGGGACGCCTACACCACCGGTCGCGGCATCATC CAGATCCGCGCCAAGGCCCACATCGAGGCGGCCAAGAAGTCTGAACGCCAGTCCATCATCGTAACCGAACTCCCCTACCA GGTTAACAAGGCCCGGCTGATAGAGAAGATCGCCGAACTGGTCAAGGAGAAGAAGATCGAGGGAATCGCCGAGATCCGCG ACGAGTCGGACCGGGAAGGGATGCGCATCGTCGTCGAGGTGAAACGGGACGATAATCCCGAGGTGCTGCTCAATCTGCTC TACAAGCTGACCCAGATGCAAACCTCCTTCGGCATCATCCTGCTGGCCATCGTACACAACCGTCCGCGCATCCTCTCGCT GAGGGAGATGATTGACTGTTTCATCGAGCACCGTGCCGAGGTGGTCACCCGCCGCACCAACTTCGAGCTGAAAAAGGCAC TGGCCCGGGCCCACATCCTGGAAGGCCTGAAGATAGCCCTGGACTGGCTGGACGCGGTGATCGAGCTGATCCGCTCCTCC AAGACCCCGCCTGAGGCCAAACAAGGGCTGATGGAAGGGGCCTTCGCCGACGCCGAATTCCTGGCGCGCCTGGAGCTCCC CCGTCCCGTAGGCTACGATGATGGCGTGCATCTGAGCGAGATCCAGGCCCAGGCCATCCTGGAGATGCGCCTGCAGCGCC TGACCGGCCTGGAGCGGGACAAGATCCTCTCCGAGTACGAGGAGATCATGAAACTGATCGCCCGCCTGCGGGAGATTCTG GCCTCGGATCGGGAGATCTTCAACATCATCATCTCTGAACTTACCGAAATAAGGGATAAATTTGGCGACATTCGCCGCTC TGAGATATCCGATACCACCCCGGACATATCCCTGGAAGACACCATCATGGATGAGGAGATGGTGGTTACCATCTCCCACA CCGGCTACATCAAGCGCAGCGCCGTTGATCTGTACCGTTCCCAGCGCCGCGGCGGCAAGGGCAAGACCGGCATGAAGACC AGGGAAGAGGATTTCGTCGAACAGCTCTTCATCGCCTCCACCAAGGACTACCTGCTCTGCTTCACCGATGCCGGCCGTAT GTACTGGCTCAAGGTCTACGAGATCCCGGAGGGGAACCGCACCACCAAGGGCAAGGCGGTGGTCAACCTGGTCAATGTGG GCATGGAGGAGAAAATCACCACCATCCTGCCGGTGAAGGAGTTCAGCGAGCATACCTTCCTGTTCATGGCCACCCGCAAC GGGGTGGTCAAGAAGACTCCGCTTATCGAATATTCCAACGTGCGCAGCGGCGGCATCATCGCCGTCAACCTGGACGACGG GGACAAGCTGATCGGCGTTGCCCTGACCGATGGCACCAAGGACGTCTTCCTGGCTTCGAGGAACGGCAAGGCCATCCGCT TCAGCGAGCAGGACGTGCGTTCCATGGGGCGCGTCACCCGCGGCGTGCGCGGCATGAACCTGAATGAGGACGATCATGTC ATCGGCATGGAGATCGTGCACAACGACGTGGTCGGCTCCACCATCTTCACGGTCTGCGAGAACGGTTACGGCAAGCGCAC CGACCTGGACGAGTATCGCGACCAGAGCCGCGGCGGCAAGGGGATCATAACCATCAAGACCAATGCCAGGAACGGCAGCG TGGTCAACGTCATGCAGGTATCAAACGACAACGACCTGATGGTGATCACCGACAATGGCAAGATCCTGCGCGTGCCTGTC TCCGGCTTCTCGGTCATCGGGCGCAACACCCAGGGGGTGCGCCTGATCACCACCGAGGAGAAGGAGAAGGTGGTGGCCGT TGCCCGCCTGGCCGAGAAGGAAGAGGACGACGAAAACGAGGGAACCGAGTAG
Upstream 100 bases:
>100_bases GACCAGGTGGACCCGCGCCGCGAATTCATTGAGACCAACGCGCTGAACGTGGTCAACCTGGACATCTAATCTTCCGTATC GAGCGATAAACGAGGTTGTA
Downstream 100 bases:
>100_bases GGGCGCCGTCCACGGCGACCGTGACTCAAACCATGCCCAGTCCCATGAACAGTACCAATGCCATGAGTAGACTTATTTCC ATCGATACCTCCCTGCGGGA
Product: DNA gyrase subunit A
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 843; Mature: 843
Protein sequence:
>843_residues MINTPQNKIAVNIEDEMKRSYMDYAMSVIIGRALPDVRDGLKPVHRRCLYAMYDMSNDWNKPYKKSARVVGDVIGKYHPH GDTAAYDTIVRMAQDFSLRYTLVDGQGNFGSIDGDRPAAMRYTEIRLRQLSHELLADLDKETVGMAPNYNDELLEPTVLP SKFPNLLINGSTGIAVGMATNIPPHNLGEVIDGIIAVINNPDLAHEELLALIPGPDFPTGATIYGRQGIRDAYTTGRGII QIRAKAHIEAAKKSERQSIIVTELPYQVNKARLIEKIAELVKEKKIEGIAEIRDESDREGMRIVVEVKRDDNPEVLLNLL YKLTQMQTSFGIILLAIVHNRPRILSLREMIDCFIEHRAEVVTRRTNFELKKALARAHILEGLKIALDWLDAVIELIRSS KTPPEAKQGLMEGAFADAEFLARLELPRPVGYDDGVHLSEIQAQAILEMRLQRLTGLERDKILSEYEEIMKLIARLREIL ASDREIFNIIISELTEIRDKFGDIRRSEISDTTPDISLEDTIMDEEMVVTISHTGYIKRSAVDLYRSQRRGGKGKTGMKT REEDFVEQLFIASTKDYLLCFTDAGRMYWLKVYEIPEGNRTTKGKAVVNLVNVGMEEKITTILPVKEFSEHTFLFMATRN GVVKKTPLIEYSNVRSGGIIAVNLDDGDKLIGVALTDGTKDVFLASRNGKAIRFSEQDVRSMGRVTRGVRGMNLNEDDHV IGMEIVHNDVVGSTIFTVCENGYGKRTDLDEYRDQSRGGKGIITIKTNARNGSVVNVMQVSNDNDLMVITDNGKILRVPV SGFSVIGRNTQGVRLITTEEKEKVVAVARLAEKEEDDENEGTE
Sequences:
>Translated_843_residues MINTPQNKIAVNIEDEMKRSYMDYAMSVIIGRALPDVRDGLKPVHRRCLYAMYDMSNDWNKPYKKSARVVGDVIGKYHPH GDTAAYDTIVRMAQDFSLRYTLVDGQGNFGSIDGDRPAAMRYTEIRLRQLSHELLADLDKETVGMAPNYNDELLEPTVLP SKFPNLLINGSTGIAVGMATNIPPHNLGEVIDGIIAVINNPDLAHEELLALIPGPDFPTGATIYGRQGIRDAYTTGRGII QIRAKAHIEAAKKSERQSIIVTELPYQVNKARLIEKIAELVKEKKIEGIAEIRDESDREGMRIVVEVKRDDNPEVLLNLL YKLTQMQTSFGIILLAIVHNRPRILSLREMIDCFIEHRAEVVTRRTNFELKKALARAHILEGLKIALDWLDAVIELIRSS KTPPEAKQGLMEGAFADAEFLARLELPRPVGYDDGVHLSEIQAQAILEMRLQRLTGLERDKILSEYEEIMKLIARLREIL ASDREIFNIIISELTEIRDKFGDIRRSEISDTTPDISLEDTIMDEEMVVTISHTGYIKRSAVDLYRSQRRGGKGKTGMKT REEDFVEQLFIASTKDYLLCFTDAGRMYWLKVYEIPEGNRTTKGKAVVNLVNVGMEEKITTILPVKEFSEHTFLFMATRN GVVKKTPLIEYSNVRSGGIIAVNLDDGDKLIGVALTDGTKDVFLASRNGKAIRFSEQDVRSMGRVTRGVRGMNLNEDDHV IGMEIVHNDVVGSTIFTVCENGYGKRTDLDEYRDQSRGGKGIITIKTNARNGSVVNVMQVSNDNDLMVITDNGKILRVPV SGFSVIGRNTQGVRLITTEEKEKVVAVARLAEKEEDDENEGTE >Mature_843_residues MINTPQNKIAVNIEDEMKRSYMDYAMSVIIGRALPDVRDGLKPVHRRCLYAMYDMSNDWNKPYKKSARVVGDVIGKYHPH GDTAAYDTIVRMAQDFSLRYTLVDGQGNFGSIDGDRPAAMRYTEIRLRQLSHELLADLDKETVGMAPNYNDELLEPTVLP SKFPNLLINGSTGIAVGMATNIPPHNLGEVIDGIIAVINNPDLAHEELLALIPGPDFPTGATIYGRQGIRDAYTTGRGII QIRAKAHIEAAKKSERQSIIVTELPYQVNKARLIEKIAELVKEKKIEGIAEIRDESDREGMRIVVEVKRDDNPEVLLNLL YKLTQMQTSFGIILLAIVHNRPRILSLREMIDCFIEHRAEVVTRRTNFELKKALARAHILEGLKIALDWLDAVIELIRSS KTPPEAKQGLMEGAFADAEFLARLELPRPVGYDDGVHLSEIQAQAILEMRLQRLTGLERDKILSEYEEIMKLIARLREIL ASDREIFNIIISELTEIRDKFGDIRRSEISDTTPDISLEDTIMDEEMVVTISHTGYIKRSAVDLYRSQRRGGKGKTGMKT REEDFVEQLFIASTKDYLLCFTDAGRMYWLKVYEIPEGNRTTKGKAVVNLVNVGMEEKITTILPVKEFSEHTFLFMATRN GVVKKTPLIEYSNVRSGGIIAVNLDDGDKLIGVALTDGTKDVFLASRNGKAIRFSEQDVRSMGRVTRGVRGMNLNEDDHV IGMEIVHNDVVGSTIFTVCENGYGKRTDLDEYRDQSRGGKGIITIKTNARNGSVVNVMQVSNDNDLMVITDNGKILRVPV SGFSVIGRNTQGVRLITTEEKEKVVAVARLAEKEEDDENEGTE
Specific function: DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings [H]
COG id: COG0188
COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the topoisomerase gyrA/parC subunit family [H]
Homologues:
Organism=Homo sapiens, GI19913406, Length=190, Percent_Identity=30, Blast_Score=71, Evalue=4e-12, Organism=Homo sapiens, GI19913408, Length=313, Percent_Identity=24.9201277955272, Blast_Score=70, Evalue=7e-12, Organism=Escherichia coli, GI1788562, Length=840, Percent_Identity=56.7857142857143, Blast_Score=941, Evalue=0.0, Organism=Escherichia coli, GI1789396, Length=528, Percent_Identity=40.719696969697, Blast_Score=374, Evalue=1e-104, Organism=Caenorhabditis elegans, GI17535065, Length=274, Percent_Identity=30.2919708029197, Blast_Score=78, Evalue=2e-14, Organism=Caenorhabditis elegans, GI212645657, Length=273, Percent_Identity=30.03663003663, Blast_Score=77, Evalue=4e-14, Organism=Caenorhabditis elegans, GI212645845, Length=327, Percent_Identity=26.2996941896024, Blast_Score=71, Evalue=3e-12, Organism=Saccharomyces cerevisiae, GI6324241, Length=176, Percent_Identity=30.1136363636364, Blast_Score=75, Evalue=5e-14,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR020899 - InterPro: IPR005743 - InterPro: IPR006691 - InterPro: IPR002205 - InterPro: IPR013758 - InterPro: IPR013757 - InterPro: IPR013760 [H]
Pfam domain/function: PF03989 DNA_gyraseA_C; PF00521 DNA_topoisoIV [H]
EC number: =5.99.1.3 [H]
Molecular weight: Translated: 94608; Mature: 94608
Theoretical pI: Translated: 5.66; Mature: 5.66
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 3.7 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 3.2 %Met (Mature Protein) 3.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MINTPQNKIAVNIEDEMKRSYMDYAMSVIIGRALPDVRDGLKPVHRRCLYAMYDMSNDWN CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC KPYKKSARVVGDVIGKYHPHGDTAAYDTIVRMAQDFSLRYTLVDGQGNFGSIDGDRPAAM CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCCHH RYTEIRLRQLSHELLADLDKETVGMAPNYNDELLEPTVLPSKFPNLLINGSTGIAVGMAT HHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEC NIPPHNLGEVIDGIIAVINNPDLAHEELLALIPGPDFPTGATIYGRQGIRDAYTTGRGII CCCCCHHHHHHHHHHHHCCCCCCCHHHHHEEECCCCCCCCCEEECCCCCHHHHHCCCCEE QIRAKAHIEAAKKSERQSIIVTELPYQVNKARLIEKIAELVKEKKIEGIAEIRDESDREG EEEEHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC MRIVVEVKRDDNPEVLLNLLYKLTQMQTSFGIILLAIVHNRPRILSLREMIDCFIEHRAE CEEEEEEECCCCHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCEEHHHHHHHHHHHHHHH VVTRRTNFELKKALARAHILEGLKIALDWLDAVIELIRSSKTPPEAKQGLMEGAFADAEF HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHH LARLELPRPVGYDDGVHLSEIQAQAILEMRLQRLTGLERDKILSEYEEIMKLIARLREIL HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH ASDREIFNIIISELTEIRDKFGDIRRSEISDTTPDISLEDTIMDEEMVVTISHTGYIKRS HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCEEEEEEECCCCHHHH AVDLYRSQRRGGKGKTGMKTREEDFVEQLFIASTKDYLLCFTDAGRMYWLKVYEIPEGNR HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEECCCCCC TTKGKAVVNLVNVGMEEKITTILPVKEFSEHTFLFMATRNGVVKKTPLIEYSNVRSGGII CCCCHHHHHHHHCCCHHHHHEEECHHHCCCCEEEEEEECCCCEECCCCEEECCCCCCCEE AVNLDDGDKLIGVALTDGTKDVFLASRNGKAIRFSEQDVRSMGRVTRGVRGMNLNEDDHV EEEECCCCEEEEEEEECCCCEEEEEECCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCE IGMEIVHNDVVGSTIFTVCENGYGKRTDLDEYRDQSRGGKGIITIKTNARNGSVVNVMQV EEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCEEEEEEE SNDNDLMVITDNGKILRVPVSGFSVIGRNTQGVRLITTEEKEKVVAVARLAEKEEDDENE CCCCCEEEEECCCEEEEEECCCEEEECCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCC GTE CCC >Mature Secondary Structure MINTPQNKIAVNIEDEMKRSYMDYAMSVIIGRALPDVRDGLKPVHRRCLYAMYDMSNDWN CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC KPYKKSARVVGDVIGKYHPHGDTAAYDTIVRMAQDFSLRYTLVDGQGNFGSIDGDRPAAM CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCCHH RYTEIRLRQLSHELLADLDKETVGMAPNYNDELLEPTVLPSKFPNLLINGSTGIAVGMAT HHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEC NIPPHNLGEVIDGIIAVINNPDLAHEELLALIPGPDFPTGATIYGRQGIRDAYTTGRGII CCCCCHHHHHHHHHHHHCCCCCCCHHHHHEEECCCCCCCCCEEECCCCCHHHHHCCCCEE QIRAKAHIEAAKKSERQSIIVTELPYQVNKARLIEKIAELVKEKKIEGIAEIRDESDREG EEEEHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC MRIVVEVKRDDNPEVLLNLLYKLTQMQTSFGIILLAIVHNRPRILSLREMIDCFIEHRAE CEEEEEEECCCCHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCEEHHHHHHHHHHHHHHH VVTRRTNFELKKALARAHILEGLKIALDWLDAVIELIRSSKTPPEAKQGLMEGAFADAEF HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHH LARLELPRPVGYDDGVHLSEIQAQAILEMRLQRLTGLERDKILSEYEEIMKLIARLREIL HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH ASDREIFNIIISELTEIRDKFGDIRRSEISDTTPDISLEDTIMDEEMVVTISHTGYIKRS HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCEEEEEEECCCCHHHH AVDLYRSQRRGGKGKTGMKTREEDFVEQLFIASTKDYLLCFTDAGRMYWLKVYEIPEGNR HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEECCCCCC TTKGKAVVNLVNVGMEEKITTILPVKEFSEHTFLFMATRNGVVKKTPLIEYSNVRSGGII CCCCHHHHHHHHCCCHHHHHEEECHHHCCCCEEEEEEECCCCEECCCCEEECCCCCCCEE AVNLDDGDKLIGVALTDGTKDVFLASRNGKAIRFSEQDVRSMGRVTRGVRGMNLNEDDHV EEEECCCCEEEEEEEECCCCEEEEEECCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCE IGMEIVHNDVVGSTIFTVCENGYGKRTDLDEYRDQSRGGKGIITIKTNARNGSVVNVMQV EEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCEEEEEEE SNDNDLMVITDNGKILRVPVSGFSVIGRNTQGVRLITTEEKEKVVAVARLAEKEEDDENE CCCCCEEEEECCCEEEEEECCCEEEECCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCC GTE CCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11677609; 8849216 [H]