| Definition | Pelobacter propionicus DSM 2379 chromosome, complete genome. |
|---|---|
| Accession | NC_008609 |
| Length | 4,008,000 |
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The map label for this gene is gyrB [H]
Identifier: 118578453
GI number: 118578453
Start: 3803
End: 6211
Strand: Direct
Name: gyrB [H]
Synonym: Ppro_0004
Alternate gene names: 118578453
Gene position: 3803-6211 (Clockwise)
Preceding gene: 118578452
Following gene: 118578454
Centisome position: 0.09
GC content: 59.32
Gene sequence:
>2409_bases ATGAGTGAACACAACAACGTGACACAGAGCAACGTTGAAGAGTACAGTGCCGATAACATCAAGGTACTGGAGGGTCTGGC CGCGGTGCGCAAGCGCCCCGCCATGTACATCGGCTCCACCTCCGGTGCGGGCCTGCACCACCTGGTGTACGAGATAGTGG ACAACTCCATCGACGAGGCCCTGGCTGGTCATTGCGACAACATCAGTGTCACCATCAATGTGGACGGCTCCGTAACCGTC ATCGACAACGGCCGCGGCATACCGACGGATATGCATCCCACCGAAGGGAGGTCGGCTGCCGAGGTCGTCCTGACCGTACT GCACGCCGGCGGCAAGTTCGATAATGATTCCTACAAGGTTTCCGGCGGTCTGCACGGCGTCGGCGTCTCGGTTGTCAACG CGCTTTCAAAATGGCTGGAACTGGAGATCAAGCGTGATGGCAAGATATTCCGCCAATCCTACCGCCGTGGCGATCCGGTT GCTCCCCTGGCCGAGACCGGCGCAACCAGGAAGCGGGGCACCAAAGTCACCTTCATGCCCGATGAGGAGATTTTCGAGAC CACCGAGTTCTCCTTTGACGTTCTCTCCCAGCGCCTGCGCGAACTGGCCTTTCTCAACGCCGGCGTGCGCATCGGCATCA GCGACATGCGGGTGGACAACAAGTCCCACGAGTTCTACTACGAGGGGGGGATCAACTCCTTCGTCGAGTACCTGAATCGC AACAAGATCGCCGTGCATCCCAAGCCGATCTACTTCCGGGGAGAGAAGGGGGGGGTGGAGACCGAGGTCTCCATGCAGTA CAACGACTCCTTCGACGAGAAAATCTTCTCCTTTGCCAACAACATCAATACCCACGAGGGGGGCACCCATCTGGTCGGCT TCAAGGCTGCCCTGACCCGCACCATGAACGCCTATGCGGCGGCCAACAATCTGCTCAAGAAGGAAAAGGTCTCCATCTCC GGTGACGACCTGCGCGAGGGGCTGACCTGCGTCATCTCGGTCAAAATCCCCCAGCCCCAGTTCGAGGGACAGACCAAGAC CAAACTGGGCAACTCGGAGGTCAAGGGATATGTGGAATCCATGATCAACGAGAAGCTGGCCCAGTTCCTGGAGGAGAATC CCCAGGTGGCCAAGCGCATCCTGGAGAAATCCATCGAGGCAGCCCGGGCAAGGGAGGCTGCCCGCAGGGCCCGCGAGACG GTGCGACGCAAGGGCGCCCTGGACCTGGGAGGGCTGCCGGGCAAACTGGCCGACTGCCAGGAGAAGAACCCCGAACATTG CGAACTGTACCTGGTGGAGGGTGACTCCGCCGGCGGCTCGGCCAAACAGGGGCGCGACCGCAAGTTCCAGGCCATCCTGC CGCTGAAGGGCAAGATCCTCAACGTGGAGAAGTCCCGTTTCGACAAGATGATCTCCTCCCAGGAGATCCGCACCCTGATC ACCGCCCTGGGCACCGGCATCGGCAAGGATGATTTCGATATCTCCAAGCTGCGCTACGGCCGGATCATCGTCATGACCGA CGCCGACGTGGACGGCTCCCACATCCTGACCCTGCTCTTAACCTTCTTCTACCGCAACATGAACGAGCTGATCCAGCGCG GCCATCTGTACATTGCCCAGCCGCCGCTCTACAAGGTCAAGCGGGGCAAGAAGGAGATGTACCTGAGGAACGAAGCGGCC CTGCAGAACTTCCTGCTGGAGGAGGGGGCCGAGGACCTGGTTCTCAGGCTGGAGAAGGGGGACCGGAAATACCTGGGAAA ACAGATCATCCCGGTGATCCGCCAGTTCATCGACAACCGGGCCATCTTCGACAAGGTGGTCAAAAAGGGAATTTCCCAGG AGTTGCTCTCCATCATCGTCCGCAGTAACGTGCCGGCTGGCCTGGAAGAGCTTTCCCAGGTAGAGCCGTATCTGGAGGCC ATGAAGGAACTGGCCGAAAACGGGGAGTACCAGGTGGAGGAGGAGCGGATCATCTTCTACATCGGCAATATCCGCGCCAT CATCGACCATCAGATCCTGGGCGTTCTGGCCAGCCACGAGTACGAACTGCTGGTGGAAAATCACCGCCGGGTGGTGGAAA CCATGGCCGACGGCCGTGCCTACATCGAGCAGGAAGCGGGTGGGAAGGTGCTGCTTGAAACATCCAACCATGAGGAATTA CTGGTATATTTTCTTGAAAACGCCAAGAAGGGTCTGGGCATCCAGCGCTACAAAGGTCTGGGCGAGATGAACCCGGACCA GCTCTGGGAGACCACCATGAATCCGGAGAACAGGGTGCTCTTGCAGGTCAAGATCGAGGATGCCGTGGAATCGGACGAGA TCTTCACCATCCTGATGGGCGACCAGGTGGACCCGCGCCGCGAATTCATTGAGACCAACGCGCTGAACGTGGTCAACCTG GACATCTAA
Upstream 100 bases:
>100_bases ACAACCACGCAACGGTCCCCGGTTCTGCTGGGCGCCGCGGCACACTGCGCCGTATTCCACGTGGAGCACGGCAATCTGAC GTTTGAGGGAAATGAAAAGC
Downstream 100 bases:
>100_bases TCTTCCGTATCGAGCGATAAACGAGGTTGTAATGATTAACACTCCGCAGAACAAGATAGCCGTCAACATCGAAGACGAGA TGAAACGTTCCTACATGGAC
Product: DNA gyrase subunit B
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 802; Mature: 801
Protein sequence:
>802_residues MSEHNNVTQSNVEEYSADNIKVLEGLAAVRKRPAMYIGSTSGAGLHHLVYEIVDNSIDEALAGHCDNISVTINVDGSVTV IDNGRGIPTDMHPTEGRSAAEVVLTVLHAGGKFDNDSYKVSGGLHGVGVSVVNALSKWLELEIKRDGKIFRQSYRRGDPV APLAETGATRKRGTKVTFMPDEEIFETTEFSFDVLSQRLRELAFLNAGVRIGISDMRVDNKSHEFYYEGGINSFVEYLNR NKIAVHPKPIYFRGEKGGVETEVSMQYNDSFDEKIFSFANNINTHEGGTHLVGFKAALTRTMNAYAAANNLLKKEKVSIS GDDLREGLTCVISVKIPQPQFEGQTKTKLGNSEVKGYVESMINEKLAQFLEENPQVAKRILEKSIEAARAREAARRARET VRRKGALDLGGLPGKLADCQEKNPEHCELYLVEGDSAGGSAKQGRDRKFQAILPLKGKILNVEKSRFDKMISSQEIRTLI TALGTGIGKDDFDISKLRYGRIIVMTDADVDGSHILTLLLTFFYRNMNELIQRGHLYIAQPPLYKVKRGKKEMYLRNEAA LQNFLLEEGAEDLVLRLEKGDRKYLGKQIIPVIRQFIDNRAIFDKVVKKGISQELLSIIVRSNVPAGLEELSQVEPYLEA MKELAENGEYQVEEERIIFYIGNIRAIIDHQILGVLASHEYELLVENHRRVVETMADGRAYIEQEAGGKVLLETSNHEEL LVYFLENAKKGLGIQRYKGLGEMNPDQLWETTMNPENRVLLQVKIEDAVESDEIFTILMGDQVDPRREFIETNALNVVNL DI
Sequences:
>Translated_802_residues MSEHNNVTQSNVEEYSADNIKVLEGLAAVRKRPAMYIGSTSGAGLHHLVYEIVDNSIDEALAGHCDNISVTINVDGSVTV IDNGRGIPTDMHPTEGRSAAEVVLTVLHAGGKFDNDSYKVSGGLHGVGVSVVNALSKWLELEIKRDGKIFRQSYRRGDPV APLAETGATRKRGTKVTFMPDEEIFETTEFSFDVLSQRLRELAFLNAGVRIGISDMRVDNKSHEFYYEGGINSFVEYLNR NKIAVHPKPIYFRGEKGGVETEVSMQYNDSFDEKIFSFANNINTHEGGTHLVGFKAALTRTMNAYAAANNLLKKEKVSIS GDDLREGLTCVISVKIPQPQFEGQTKTKLGNSEVKGYVESMINEKLAQFLEENPQVAKRILEKSIEAARAREAARRARET VRRKGALDLGGLPGKLADCQEKNPEHCELYLVEGDSAGGSAKQGRDRKFQAILPLKGKILNVEKSRFDKMISSQEIRTLI TALGTGIGKDDFDISKLRYGRIIVMTDADVDGSHILTLLLTFFYRNMNELIQRGHLYIAQPPLYKVKRGKKEMYLRNEAA LQNFLLEEGAEDLVLRLEKGDRKYLGKQIIPVIRQFIDNRAIFDKVVKKGISQELLSIIVRSNVPAGLEELSQVEPYLEA MKELAENGEYQVEEERIIFYIGNIRAIIDHQILGVLASHEYELLVENHRRVVETMADGRAYIEQEAGGKVLLETSNHEEL LVYFLENAKKGLGIQRYKGLGEMNPDQLWETTMNPENRVLLQVKIEDAVESDEIFTILMGDQVDPRREFIETNALNVVNL DI >Mature_801_residues SEHNNVTQSNVEEYSADNIKVLEGLAAVRKRPAMYIGSTSGAGLHHLVYEIVDNSIDEALAGHCDNISVTINVDGSVTVI DNGRGIPTDMHPTEGRSAAEVVLTVLHAGGKFDNDSYKVSGGLHGVGVSVVNALSKWLELEIKRDGKIFRQSYRRGDPVA PLAETGATRKRGTKVTFMPDEEIFETTEFSFDVLSQRLRELAFLNAGVRIGISDMRVDNKSHEFYYEGGINSFVEYLNRN KIAVHPKPIYFRGEKGGVETEVSMQYNDSFDEKIFSFANNINTHEGGTHLVGFKAALTRTMNAYAAANNLLKKEKVSISG DDLREGLTCVISVKIPQPQFEGQTKTKLGNSEVKGYVESMINEKLAQFLEENPQVAKRILEKSIEAARAREAARRARETV RRKGALDLGGLPGKLADCQEKNPEHCELYLVEGDSAGGSAKQGRDRKFQAILPLKGKILNVEKSRFDKMISSQEIRTLIT ALGTGIGKDDFDISKLRYGRIIVMTDADVDGSHILTLLLTFFYRNMNELIQRGHLYIAQPPLYKVKRGKKEMYLRNEAAL QNFLLEEGAEDLVLRLEKGDRKYLGKQIIPVIRQFIDNRAIFDKVVKKGISQELLSIIVRSNVPAGLEELSQVEPYLEAM KELAENGEYQVEEERIIFYIGNIRAIIDHQILGVLASHEYELLVENHRRVVETMADGRAYIEQEAGGKVLLETSNHEELL VYFLENAKKGLGIQRYKGLGEMNPDQLWETTMNPENRVLLQVKIEDAVESDEIFTILMGDQVDPRREFIETNALNVVNLD I
Specific function: DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings [H]
COG id: COG0187
COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 Toprim domain [H]
Homologues:
Organism=Homo sapiens, GI19913406, Length=577, Percent_Identity=25.6499133448873, Blast_Score=139, Evalue=1e-32, Organism=Homo sapiens, GI19913408, Length=531, Percent_Identity=25.8003766478343, Blast_Score=132, Evalue=1e-30, Organism=Escherichia coli, GI48994957, Length=801, Percent_Identity=53.9325842696629, Blast_Score=815, Evalue=0.0, Organism=Escherichia coli, GI1789408, Length=552, Percent_Identity=41.304347826087, Blast_Score=420, Evalue=1e-118, Organism=Caenorhabditis elegans, GI212645845, Length=505, Percent_Identity=27.7227722772277, Blast_Score=150, Evalue=2e-36, Organism=Caenorhabditis elegans, GI17535065, Length=550, Percent_Identity=26.9090909090909, Blast_Score=148, Evalue=1e-35, Organism=Caenorhabditis elegans, GI212645657, Length=158, Percent_Identity=35.4430379746835, Blast_Score=80, Evalue=4e-15, Organism=Saccharomyces cerevisiae, GI6324241, Length=645, Percent_Identity=25.4263565891473, Blast_Score=127, Evalue=9e-30, Organism=Drosophila melanogaster, GI17136538, Length=534, Percent_Identity=26.7790262172285, Blast_Score=150, Evalue=4e-36,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR011557 - InterPro: IPR020568 - InterPro: IPR014721 - InterPro: IPR001241 - InterPro: IPR013759 - InterPro: IPR002288 - InterPro: IPR013506 - InterPro: IPR013760 - InterPro: IPR018522 - InterPro: IPR006171 [H]
Pfam domain/function: PF00204 DNA_gyraseB; PF00986 DNA_gyraseB_C; PF02518 HATPase_c; PF01751 Toprim [H]
EC number: =5.99.1.3 [H]
Molecular weight: Translated: 89857; Mature: 89725
Theoretical pI: Translated: 5.71; Mature: 5.71
Prosite motif: PS00177 TOPOISOMERASE_II
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSEHNNVTQSNVEEYSADNIKVLEGLAAVRKRPAMYIGSTSGAGLHHLVYEIVDNSIDEA CCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCHHHHH LAGHCDNISVTINVDGSVTVIDNGRGIPTDMHPTEGRSAAEVVLTVLHAGGKFDNDSYKV HHCCCCCEEEEEEECCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEE SGGLHGVGVSVVNALSKWLELEIKRDGKIFRQSYRRGDPVAPLAETGATRKRGTKVTFMP CCCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHCCCCCCCHHHCCCCCCCCCEEEECC DEEIFETTEFSFDVLSQRLRELAFLNAGVRIGISDMRVDNKSHEFYYEGGINSFVEYLNR CHHHHHHHCCCHHHHHHHHHHHHHHCCCCEECCHHEEECCCCCCEEEECCHHHHHHHHCC NKIAVHPKPIYFRGEKGGVETEVSMQYNDSFDEKIFSFANNINTHEGGTHLVGFKAALTR CCEEECCCCEEEECCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCEEEEHHHHHHH TMNAYAAANNLLKKEKVSISGDDLREGLTCVISVKIPQPQFEGQTKTKLGNSEVKGYVES HHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEEECCCCCCCCCHHHCCCCHHHHHHHHH MINEKLAQFLEENPQVAKRILEKSIEAARAREAARRARETVRRKGALDLGGLPGKLADCQ HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH EKNPEHCELYLVEGDSAGGSAKQGRDRKFQAILPLKGKILNVEKSRFDKMISSQEIRTLI CCCCCCEEEEEEECCCCCCCCCCCCCCCEEEECCCCCEEEECHHHHHHHHHHHHHHHHHH TALGTGIGKDDFDISKLRYGRIIVMTDADVDGSHILTLLLTFFYRNMNELIQRGHLYIAQ HHHHCCCCCCCCCHHHEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEC PPLYKVKRGKKEMYLRNEAALQNFLLEEGAEDLVLRLEKGDRKYLGKQIIPVIRQFIDNR CCCHHHHCCCHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCHHHHHHHHHHHHHHHHCCH AIFDKVVKKGISQELLSIIVRSNVPAGLEELSQVEPYLEAMKELAENGEYQVEEERIIFY HHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEE IGNIRAIIDHQILGVLASHEYELLVENHRRVVETMADGRAYIEQEAGGKVLLETSNHEEL ECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEECCCCCCE LVYFLENAKKGLGIQRYKGLGEMNPDQLWETTMNPENRVLLQVKIEDAVESDEIFTILMG EHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHCCCCCCEEEEEEEECCCCCCCCEEEEEEC DQVDPRREFIETNALNVVNLDI CCCCHHHHHHHCCCCEEEEECC >Mature Secondary Structure SEHNNVTQSNVEEYSADNIKVLEGLAAVRKRPAMYIGSTSGAGLHHLVYEIVDNSIDEA CCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCHHHHH LAGHCDNISVTINVDGSVTVIDNGRGIPTDMHPTEGRSAAEVVLTVLHAGGKFDNDSYKV HHCCCCCEEEEEEECCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEE SGGLHGVGVSVVNALSKWLELEIKRDGKIFRQSYRRGDPVAPLAETGATRKRGTKVTFMP CCCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHCCCCCCCHHHCCCCCCCCCEEEECC DEEIFETTEFSFDVLSQRLRELAFLNAGVRIGISDMRVDNKSHEFYYEGGINSFVEYLNR CHHHHHHHCCCHHHHHHHHHHHHHHCCCCEECCHHEEECCCCCCEEEECCHHHHHHHHCC NKIAVHPKPIYFRGEKGGVETEVSMQYNDSFDEKIFSFANNINTHEGGTHLVGFKAALTR CCEEECCCCEEEECCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCEEEEHHHHHHH TMNAYAAANNLLKKEKVSISGDDLREGLTCVISVKIPQPQFEGQTKTKLGNSEVKGYVES HHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEEECCCCCCCCCHHHCCCCHHHHHHHHH MINEKLAQFLEENPQVAKRILEKSIEAARAREAARRARETVRRKGALDLGGLPGKLADCQ HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH EKNPEHCELYLVEGDSAGGSAKQGRDRKFQAILPLKGKILNVEKSRFDKMISSQEIRTLI CCCCCCEEEEEEECCCCCCCCCCCCCCCEEEECCCCCEEEECHHHHHHHHHHHHHHHHHH TALGTGIGKDDFDISKLRYGRIIVMTDADVDGSHILTLLLTFFYRNMNELIQRGHLYIAQ HHHHCCCCCCCCCHHHEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEC PPLYKVKRGKKEMYLRNEAALQNFLLEEGAEDLVLRLEKGDRKYLGKQIIPVIRQFIDNR CCCHHHHCCCHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCHHHHHHHHHHHHHHHHCCH AIFDKVVKKGISQELLSIIVRSNVPAGLEELSQVEPYLEAMKELAENGEYQVEEERIIFY HHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEE IGNIRAIIDHQILGVLASHEYELLVENHRRVVETMADGRAYIEQEAGGKVLLETSNHEEL ECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEECCCCCCE LVYFLENAKKGLGIQRYKGLGEMNPDQLWETTMNPENRVLLQVKIEDAVESDEIFTILMG EHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHCCCCCCEEEEEEEECCCCCCCCEEEEEEC DQVDPRREFIETNALNVVNLDI CCCCHHHHHHHCCCCEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12620739; 9464408 [H]