Click here to switch to the map view.

The map label for this gene is manA [H]

Identifier: 118480308

GI number: 118480308

Start: 5024784

End: 5025731

Strand: Reverse

Name: manA [H]

Synonym: BALH_4769

Alternate gene names: 118480308

Gene position: 5025731-5024784 (Counterclockwise)

Preceding gene: 118480309

Following gene: 118480307

Centisome position: 95.6

GC content: 35.02

Gene sequence:

>948_bases
TTGTATAAAGAACCATTATTTTTTCAACCAGTATTACAGGAGCGGATTTGGGGAGGAGAATCTTTAAAAGAATTTAATTA
TGAGTTACCTTCACAAACTACTGGTGAATGCTGGGGAATTTCTGCTCATTTAAATGGACCGAGTATCGTAAAGAGCGGTA
AATATAAAGGTTTAACATTGAGGCAACTATGGGATGAACATAGAGCATTATTCGGGAACTATCAAGCTGAGCAGTTCCCT
TTATTAACTAAAATCCTAGATGCAAAAAAAGACTTATCTGTACAAGTACATCCGAATGATGAATTTGCTAACATATATGA
GCGTGGTGAATTAGGGAAGACAGAGTGCTGGTATATTATTGATTGTAAGGAAGATGCAGAAATAGTATATGGTCATACTG
CTCAAACCAGAGAAGAATTTAAGGAAATGGTTGAGCAGGGGAACTGGGATCGATTACTTCAGCGTAAAAAAATCCAGCCG
GGTGAATTTTTTTACGTACCAAGCGGAACTATCCATGCGCTATGTGAAGGTACATTAGTATTGGAAACACAGCAAAGTTC
AGATACGACGTATCGTGTGTATGATTATGATCGTGTTGATGGTGATGGAAATAAGCGAGAATTACATGTTGAAAAATCAA
TTGCTGTATCGATGATTCCGCATCAGGATTATCAAGTTTATCCTGAAATAAAAAAAGAGAATGGCGCCGTTGTTACTAAA
TATGTACAAGAAAAGTATTTTTCAGTTAATAAATGGGAAATTGAAATGGAAGCATCTTTTCAACAGAATAAACCATTCCA
ATTAGCTAGTGTAATTGAAGGTGAAGCAACTTTAAGAACTGTAAACGGAGAATTTCTTATAAAAAAAGGAGATCACTTTA
TTCTTCCTGATGGAATTGAAAGTTTTGTTTTAAAAGGAAATGTGACTTTAATTGTTTCTCATCCATAG

Upstream 100 bases:

>100_bases
AAGATATTGTCCGGATTTATATGCAATGGAACGAGATAGAGGAAGCTTGTTATTTAAAAAGTAAAAATTAGTAGTAAGTG
CAACTAGAGGTGGAGTCATT

Downstream 100 bases:

>100_bases
AATAGGTCAAATTAATTTTGTGATTTCACTTTATCATTTATTAGTATTGCTATAATATAATGAAGAGGTCTTAGCATTTT
ATTTGTAATTATAAGCAAAG

Product: mannose-6-phosphate isomerase

Products: NA

Alternate protein names: Phosphohexomutase; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MYKEPLFFQPVLQERIWGGESLKEFNYELPSQTTGECWGISAHLNGPSIVKSGKYKGLTLRQLWDEHRALFGNYQAEQFP
LLTKILDAKKDLSVQVHPNDEFANIYERGELGKTECWYIIDCKEDAEIVYGHTAQTREEFKEMVEQGNWDRLLQRKKIQP
GEFFYVPSGTIHALCEGTLVLETQQSSDTTYRVYDYDRVDGDGNKRELHVEKSIAVSMIPHQDYQVYPEIKKENGAVVTK
YVQEKYFSVNKWEIEMEASFQQNKPFQLASVIEGEATLRTVNGEFLIKKGDHFILPDGIESFVLKGNVTLIVSHP

Sequences:

>Translated_315_residues
MYKEPLFFQPVLQERIWGGESLKEFNYELPSQTTGECWGISAHLNGPSIVKSGKYKGLTLRQLWDEHRALFGNYQAEQFP
LLTKILDAKKDLSVQVHPNDEFANIYERGELGKTECWYIIDCKEDAEIVYGHTAQTREEFKEMVEQGNWDRLLQRKKIQP
GEFFYVPSGTIHALCEGTLVLETQQSSDTTYRVYDYDRVDGDGNKRELHVEKSIAVSMIPHQDYQVYPEIKKENGAVVTK
YVQEKYFSVNKWEIEMEASFQQNKPFQLASVIEGEATLRTVNGEFLIKKGDHFILPDGIESFVLKGNVTLIVSHP
>Mature_315_residues
MYKEPLFFQPVLQERIWGGESLKEFNYELPSQTTGECWGISAHLNGPSIVKSGKYKGLTLRQLWDEHRALFGNYQAEQFP
LLTKILDAKKDLSVQVHPNDEFANIYERGELGKTECWYIIDCKEDAEIVYGHTAQTREEFKEMVEQGNWDRLLQRKKIQP
GEFFYVPSGTIHALCEGTLVLETQQSSDTTYRVYDYDRVDGDGNKRELHVEKSIAVSMIPHQDYQVYPEIKKENGAVVTK
YVQEKYFSVNKWEIEMEASFQQNKPFQLASVIEGEATLRTVNGEFLIKKGDHFILPDGIESFVLKGNVTLIVSHP

Specific function: Unknown

COG id: COG1482

COG function: function code G; Phosphomannose isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR001250
- InterPro:   IPR014628
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01238 PMI_typeI [H]

EC number: =5.3.1.8 [H]

Molecular weight: Translated: 36330; Mature: 36330

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKEPLFFQPVLQERIWGGESLKEFNYELPSQTTGECWGISAHLNGPSIVKSGKYKGLTL
CCCCCCCHHHHHHHHHCCCCCHHHCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCCHH
RQLWDEHRALFGNYQAEQFPLLTKILDAKKDLSVQVHPNDEFANIYERGELGKTECWYII
HHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHCCCCCCCEEEEEE
DCKEDAEIVYGHTAQTREEFKEMVEQGNWDRLLQRKKIQPGEFFYVPSGTIHALCEGTLV
ECCCCCEEEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEECCCCEEEEECCEEE
LETQQSSDTTYRVYDYDRVDGDGNKRELHVEKSIAVSMIPHQDYQVYPEIKKENGAVVTK
EEECCCCCCEEEEEEEEEECCCCCCEEEEEECCEEEEECCCCCCEECCCEECCCCCEEEH
YVQEKYFSVNKWEIEMEASFQQNKPFQLASVIEGEATLRTVNGEFLIKKGDHFILPDGIE
HHHHHHCCCEEEEEEEEECCCCCCCEEEEHHHCCCEEEEEECCEEEEECCCEEEECCCHH
SFVLKGNVTLIVSHP
HEEEECCEEEEEECC
>Mature Secondary Structure
MYKEPLFFQPVLQERIWGGESLKEFNYELPSQTTGECWGISAHLNGPSIVKSGKYKGLTL
CCCCCCCHHHHHHHHHCCCCCHHHCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCCHH
RQLWDEHRALFGNYQAEQFPLLTKILDAKKDLSVQVHPNDEFANIYERGELGKTECWYII
HHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHCCCCCCCEEEEEE
DCKEDAEIVYGHTAQTREEFKEMVEQGNWDRLLQRKKIQPGEFFYVPSGTIHALCEGTLV
ECCCCCEEEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEECCCCEEEEECCEEE
LETQQSSDTTYRVYDYDRVDGDGNKRELHVEKSIAVSMIPHQDYQVYPEIKKENGAVVTK
EEECCCCCCEEEEEEEEEECCCCCCEEEEEECCEEEEECCCCCCEECCCEECCCCCEEEH
YVQEKYFSVNKWEIEMEASFQQNKPFQLASVIEGEATLRTVNGEFLIKKGDHFILPDGIE
HHHHHHCCCEEEEEEEEECCCCCCCEEEEHHHCCCEEEEEECCEEEEECCCEEEECCCHH
SFVLKGNVTLIVSHP
HEEEECCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]