| Definition | Bacillus thuringiensis str. Al Hakam chromosome, complete genome. |
|---|---|
| Accession | NC_008600 |
| Length | 5,257,091 |
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The map label for this gene is comEC [H]
Identifier: 118479491
GI number: 118479491
Start: 4125480
End: 4127801
Strand: Reverse
Name: comEC [H]
Synonym: BALH_3913
Alternate gene names: 118479491
Gene position: 4127801-4125480 (Counterclockwise)
Preceding gene: 118479492
Following gene: 118479490
Centisome position: 78.52
GC content: 36.39
Gene sequence:
>2322_bases TTGCAAGGACAATGGGGCTACGTTGCAATCTCATTTATAATAGGGATTGCAATCGCCTTCTCCTCTTCAGTTGTATTGCT GACTTGTTGTCTCGTTCTATATGTTTTCTTTTGTTTGTATCGTACTTCGCGTAAAACCTTCCTTTATTGTATGATAGTGT GTTTTAGTGGCGCTATGTACACCACGTATGTTCAAGGGCAAAATAAGCCTCTGGGAGAGTCCTACGAAGCTACAAGAGGA GTGATATATAATACACCTCTTATTAACGGGGATCGCCTATCATTTCAAGTTGAAGATCAGAATAAAAATATAGTGCAGTT AAGTTACAAAATGAAATCAGCCTCGGAAAAGAAACAAATGCGACAATTACATGCAGGAGTGTCATGTATATTTGATGGCG AGAGGAAAGAACCACAAATAGCTCGGAATTTTCATGGGTTTAATTATCGTGATTATTTATATAAGCAAAATATTCATTTC ATATTGGAAGCTACATATATTTCTGAATGCCGTAAAACATCGTTGTCACTTGTGCAATGGATTCTTCTTTTGAGGCAGCA AGCAATCTTAGGAGTTACAGAAATGTTTCCAGAGCAATCAGGCGCTTTTATGAACGCGTTACTATTTGGTGATAGACAAC AAATGACATTTGAAGTTGAAGAGCAATATCAACAATTCGGTCTTGTGCATTTGTTGGCGATTTCAGGATCGCATATCGTA TTGTTAATGGTGATTGTGTATTTTATTTTGCTAAGAAGTGGTGTGACAAGGGAGATAGCAACAGTATGTCTTATCTTCTT CATTCCTATATATATGATTTTAGCAGGAGCGTCACCGTCTGTTATAAGAGCTTCTATAACAGGAGTTTTAATGTTAATTG CTTTTATGTGTTCTATTCGTTTATCTAGCTTAGATGCTTTAAGTATAACAGCTATATGTATGCTTATATTTGATCCATAT CTCGTGTTTAATATTGGCTTTCAGTTTTCTTTCGTTGGGAGTTTTGCTTTACTTTTATCTGCCCCGCTCTTACTAGAGAG TGGTAATGGAGTAATTAGAAATTCTATTTATATTTCTCTTATTTCACAGCTCGTTAGTACTCCGATTTTGTTATATCACT TCGGTTATTATTCTCCATATAGTATTTTTCTAAATATCCTTTACGTTCCGTTTTTATCTCTCATTGTATTGCCGTGTAGT ATTATTATTTTGATATGTTTGCCGATCATCCCGTTTCTTGCAAAAAGCTTTGCGAATGTACTATCAATAGGTTTGAATCT TTCTAATGATTTTTTAAGTTATTGTGAAAGTTTACCATTTACCCGTCTTAATTTCGGGCAAACACCTATACTTCTGGTAG CCTTATATTGCGTGAGTATTATTAGTGTATTGATGGTTTGGGAAAGGCGAATATCTAAGGGAATGGTGTTTATATTTGCG GGCATATTTCTTTTCATTAGTACAGGTCATTATGTATATCCGTATTTTCGAGAAAGTGGGAGTGTTACATTTCTTGATGT TGGCCAGGGGGATGCAATATTAATTCGCCTCCCGTATGATCAAGAGATTTACCTTATTGACACTGGTGGAACAATTCGTT TAAACAAGGAAGAATGGCAACGGAAAAAACATGAATTTTCTGTTGGAAATGATATTTTGATCCCTTATTTACAAAAGGAA GGTATTAAAAAAATTGATAAATTAATCGTAACGCATGGAGATGCAGATCATATCGGTGCTGCACAAGAATTATTATCAAA TATAACCGTAAAAGAAGTTGTATTTGGTCGAAAGGAACAAGAGGCAATATTAGAAAAAGCAGTAAAGAAACAGGCGTTAG AAAAGGAAGTGAAAATAAGTGAAGTGGGGGAAGGAGAGAGTTGGCGCGTAAATGAAGCGGAATTTTTTGTGCTAGCACCA ACAGGGAAAGAAAGAAGTGAAAATAACGCTTCAATTGTACTGTGGGCAAAATTAGGAGGGATAACGTGGCTGTTTACAGG TGATTTAGAAGAAGAAGGAGAGAAGGGTTTAGTAGCTACATATCCAGATTTACGGGCGGATGTTTTAAAGGTTGCTCATC ATGGAAGTAATACGTCATCTATAACGCCTTTTTTGAGCGCCGTACAGCCTAATATAGCGATTATTTCTGTCGGTGAACGG AATAGGTATGGGCACCCTCATAAGGAAGTTATAGAGCGTTTTGAGAAGATGGGGATTGAAATATGGCGCACGGATAAGCA AGGTGCTATTTCCTATGTTTTTAAAGAGGAACGCGGAACGTTTCGTAGCAAAATCACATATGATGAAACACGGAATAGAT AA
Upstream 100 bases:
>100_bases AAGAACTATTTGCATCTTTAGAAAAAGAGAACTTATCAATGGAAGAATTACAGCATGTATTCACGAAAGCAAAAATGATG CTATAAGGAGTGAGTATGAG
Downstream 100 bases:
>100_bases AAAAAAGACTGCTAGTAAGCAGCAGTCTTTAAGAACCGATAAATTTAATAACAGTTGCAATGATGAAAAGTGTTGCGAAA AAACCAAATGAGACGATAAA
Product: DNA internalization-related competence protein
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 773; Mature: 773
Protein sequence:
>773_residues MQGQWGYVAISFIIGIAIAFSSSVVLLTCCLVLYVFFCLYRTSRKTFLYCMIVCFSGAMYTTYVQGQNKPLGESYEATRG VIYNTPLINGDRLSFQVEDQNKNIVQLSYKMKSASEKKQMRQLHAGVSCIFDGERKEPQIARNFHGFNYRDYLYKQNIHF ILEATYISECRKTSLSLVQWILLLRQQAILGVTEMFPEQSGAFMNALLFGDRQQMTFEVEEQYQQFGLVHLLAISGSHIV LLMVIVYFILLRSGVTREIATVCLIFFIPIYMILAGASPSVIRASITGVLMLIAFMCSIRLSSLDALSITAICMLIFDPY LVFNIGFQFSFVGSFALLLSAPLLLESGNGVIRNSIYISLISQLVSTPILLYHFGYYSPYSIFLNILYVPFLSLIVLPCS IIILICLPIIPFLAKSFANVLSIGLNLSNDFLSYCESLPFTRLNFGQTPILLVALYCVSIISVLMVWERRISKGMVFIFA GIFLFISTGHYVYPYFRESGSVTFLDVGQGDAILIRLPYDQEIYLIDTGGTIRLNKEEWQRKKHEFSVGNDILIPYLQKE GIKKIDKLIVTHGDADHIGAAQELLSNITVKEVVFGRKEQEAILEKAVKKQALEKEVKISEVGEGESWRVNEAEFFVLAP TGKERSENNASIVLWAKLGGITWLFTGDLEEEGEKGLVATYPDLRADVLKVAHHGSNTSSITPFLSAVQPNIAIISVGER NRYGHPHKEVIERFEKMGIEIWRTDKQGAISYVFKEERGTFRSKITYDETRNR
Sequences:
>Translated_773_residues MQGQWGYVAISFIIGIAIAFSSSVVLLTCCLVLYVFFCLYRTSRKTFLYCMIVCFSGAMYTTYVQGQNKPLGESYEATRG VIYNTPLINGDRLSFQVEDQNKNIVQLSYKMKSASEKKQMRQLHAGVSCIFDGERKEPQIARNFHGFNYRDYLYKQNIHF ILEATYISECRKTSLSLVQWILLLRQQAILGVTEMFPEQSGAFMNALLFGDRQQMTFEVEEQYQQFGLVHLLAISGSHIV LLMVIVYFILLRSGVTREIATVCLIFFIPIYMILAGASPSVIRASITGVLMLIAFMCSIRLSSLDALSITAICMLIFDPY LVFNIGFQFSFVGSFALLLSAPLLLESGNGVIRNSIYISLISQLVSTPILLYHFGYYSPYSIFLNILYVPFLSLIVLPCS IIILICLPIIPFLAKSFANVLSIGLNLSNDFLSYCESLPFTRLNFGQTPILLVALYCVSIISVLMVWERRISKGMVFIFA GIFLFISTGHYVYPYFRESGSVTFLDVGQGDAILIRLPYDQEIYLIDTGGTIRLNKEEWQRKKHEFSVGNDILIPYLQKE GIKKIDKLIVTHGDADHIGAAQELLSNITVKEVVFGRKEQEAILEKAVKKQALEKEVKISEVGEGESWRVNEAEFFVLAP TGKERSENNASIVLWAKLGGITWLFTGDLEEEGEKGLVATYPDLRADVLKVAHHGSNTSSITPFLSAVQPNIAIISVGER NRYGHPHKEVIERFEKMGIEIWRTDKQGAISYVFKEERGTFRSKITYDETRNR >Mature_773_residues MQGQWGYVAISFIIGIAIAFSSSVVLLTCCLVLYVFFCLYRTSRKTFLYCMIVCFSGAMYTTYVQGQNKPLGESYEATRG VIYNTPLINGDRLSFQVEDQNKNIVQLSYKMKSASEKKQMRQLHAGVSCIFDGERKEPQIARNFHGFNYRDYLYKQNIHF ILEATYISECRKTSLSLVQWILLLRQQAILGVTEMFPEQSGAFMNALLFGDRQQMTFEVEEQYQQFGLVHLLAISGSHIV LLMVIVYFILLRSGVTREIATVCLIFFIPIYMILAGASPSVIRASITGVLMLIAFMCSIRLSSLDALSITAICMLIFDPY LVFNIGFQFSFVGSFALLLSAPLLLESGNGVIRNSIYISLISQLVSTPILLYHFGYYSPYSIFLNILYVPFLSLIVLPCS IIILICLPIIPFLAKSFANVLSIGLNLSNDFLSYCESLPFTRLNFGQTPILLVALYCVSIISVLMVWERRISKGMVFIFA GIFLFISTGHYVYPYFRESGSVTFLDVGQGDAILIRLPYDQEIYLIDTGGTIRLNKEEWQRKKHEFSVGNDILIPYLQKE GIKKIDKLIVTHGDADHIGAAQELLSNITVKEVVFGRKEQEAILEKAVKKQALEKEVKISEVGEGESWRVNEAEFFVLAP TGKERSENNASIVLWAKLGGITWLFTGDLEEEGEKGLVATYPDLRADVLKVAHHGSNTSSITPFLSAVQPNIAIISVGER NRYGHPHKEVIERFEKMGIEIWRTDKQGAISYVFKEERGTFRSKITYDETRNR
Specific function: The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding [H]
COG id: COG2333
COG function: function code R; Predicted hydrolase (metallo-beta-lactamase superfamily)
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: To H.influenzae REC2, N.gonorrhoeae ComA and E.coli YcaI [H]
Homologues:
Organism=Escherichia coli, GI87081801, Length=601, Percent_Identity=22.4625623960067, Blast_Score=100, Evalue=4e-22,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001279 - InterPro: IPR004477 - InterPro: IPR004797 [H]
Pfam domain/function: PF03772 Competence; PF00753 Lactamase_B [H]
EC number: NA
Molecular weight: Translated: 87369; Mature: 87369
Theoretical pI: Translated: 7.47; Mature: 7.47
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.8 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 1.8 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQGQWGYVAISFIIGIAIAFSSSVVLLTCCLVLYVFFCLYRTSRKTFLYCMIVCFSGAMY CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEE TTYVQGQNKPLGESYEATRGVIYNTPLINGDRLSFQVEDQNKNIVQLSYKMKSASEKKQM EEEEECCCCCCCCCHHHHCCEEEECCEECCCEEEEEEECCCCCEEEEEEHHHHHHHHHHH RQLHAGVSCIFDGERKEPQIARNFHGFNYRDYLYKQNIHFILEATYISECRKTSLSLVQW HHHHCCCEEEECCCCCCCHHHHHCCCCCHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHH ILLLRQQAILGVTEMFPEQSGAFMNALLFGDRQQMTFEVEEQYQQFGLVHLLAISGSHIV HHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHEEEHHHHHHHHHCHHEEEEECCCHHH LLMVIVYFILLRSGVTREIATVCLIFFIPIYMILAGASPSVIRASITGVLMLIAFMCSIR HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH LSSLDALSITAICMLIFDPYLVFNIGFQFSFVGSFALLLSAPLLLESGNGVIRNSIYISL HHCCCHHHHHHHHHHHHCCHHEEEECCHHHHHHHHHHHHHCCCEEECCCCEEHHHHHHHH ISQLVSTPILLYHFGYYSPYSIFLNILYVPFLSLIVLPCSIIILICLPIIPFLAKSFANV HHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LSIGLNLSNDFLSYCESLPFTRLNFGQTPILLVALYCVSIISVLMVWERRISKGMVFIFA HHHCCCCCHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH GIFLFISTGHYVYPYFRESGSVTFLDVGQGDAILIRLPYDQEIYLIDTGGTIRLNKEEWQ HHHHHHHCCCEEEEEEECCCCEEEEEECCCCEEEEEECCCCEEEEEECCCEEEECHHHHH RKKHEFSVGNDILIPYLQKEGIKKIDKLIVTHGDADHIGAAQELLSNITVKEVVFGRKEQ HHHHCCCCCCCEEEHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCHHHHHHCCCHH EAILEKAVKKQALEKEVKISEVGEGESWRVNEAEFFVLAPTGKERSENNASIVLWAKLGG HHHHHHHHHHHHHHHHCCHHCCCCCCCEEECCCEEEEECCCCCCCCCCCCEEEEEEEECC ITWLFTGDLEEEGEKGLVATYPDLRADVLKVAHHGSNTSSITPFLSAVQPNIAIISVGER EEEEEECCCHHCCCCCEEEECCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEECCC NRYGHPHKEVIERFEKMGIEIWRTDKQGAISYVFKEERGTFRSKITYDETRNR CCCCCCHHHHHHHHHHCCCEEEECCCCCCEEEEEECCCCCHHHCEECHHCCCC >Mature Secondary Structure MQGQWGYVAISFIIGIAIAFSSSVVLLTCCLVLYVFFCLYRTSRKTFLYCMIVCFSGAMY CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEE TTYVQGQNKPLGESYEATRGVIYNTPLINGDRLSFQVEDQNKNIVQLSYKMKSASEKKQM EEEEECCCCCCCCCHHHHCCEEEECCEECCCEEEEEEECCCCCEEEEEEHHHHHHHHHHH RQLHAGVSCIFDGERKEPQIARNFHGFNYRDYLYKQNIHFILEATYISECRKTSLSLVQW HHHHCCCEEEECCCCCCCHHHHHCCCCCHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHH ILLLRQQAILGVTEMFPEQSGAFMNALLFGDRQQMTFEVEEQYQQFGLVHLLAISGSHIV HHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHEEEHHHHHHHHHCHHEEEEECCCHHH LLMVIVYFILLRSGVTREIATVCLIFFIPIYMILAGASPSVIRASITGVLMLIAFMCSIR HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH LSSLDALSITAICMLIFDPYLVFNIGFQFSFVGSFALLLSAPLLLESGNGVIRNSIYISL HHCCCHHHHHHHHHHHHCCHHEEEECCHHHHHHHHHHHHHCCCEEECCCCEEHHHHHHHH ISQLVSTPILLYHFGYYSPYSIFLNILYVPFLSLIVLPCSIIILICLPIIPFLAKSFANV HHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LSIGLNLSNDFLSYCESLPFTRLNFGQTPILLVALYCVSIISVLMVWERRISKGMVFIFA HHHCCCCCHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH GIFLFISTGHYVYPYFRESGSVTFLDVGQGDAILIRLPYDQEIYLIDTGGTIRLNKEEWQ HHHHHHHCCCEEEEEEECCCCEEEEEECCCCEEEEEECCCCEEEEEECCCEEEECHHHHH RKKHEFSVGNDILIPYLQKEGIKKIDKLIVTHGDADHIGAAQELLSNITVKEVVFGRKEQ HHHHCCCCCCCEEEHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCHHHHHHCCCHH EAILEKAVKKQALEKEVKISEVGEGESWRVNEAEFFVLAPTGKERSENNASIVLWAKLGG HHHHHHHHHHHHHHHHCCHHCCCCCCCEEECCCEEEEECCCCCCCCCCCCEEEEEEEECC ITWLFTGDLEEEGEKGLVATYPDLRADVLKVAHHGSNTSSITPFLSAVQPNIAIISVGER EEEEEECCCHHCCCCCEEEECCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEECCC NRYGHPHKEVIERFEKMGIEIWRTDKQGAISYVFKEERGTFRSKITYDETRNR CCCCCCHHHHHHHHHHCCCEEEECCCCCCEEEEEECCCCCHHHCEECHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 7968523; 8969508; 9384377 [H]