Click here to switch to the map view.

The map label for this gene is pyrD [H]

Identifier: 118479105

GI number: 118479105

Start: 3731512

End: 3732441

Strand: Reverse

Name: pyrD [H]

Synonym: BALH_3514

Alternate gene names: 118479105

Gene position: 3732441-3731512 (Counterclockwise)

Preceding gene: 118479106

Following gene: 118479104

Centisome position: 71.0

GC content: 40.43

Gene sequence:

>930_bases
ATGAACAGATTGCAAGTTGAATTACCAGGATTATCATTAAAAAATCCAATTATACCGGCATCTGGATGCTTTGGATTTGG
TCGTGAATATGCACAGTTTTACGATTTAAGTGTACTAGGATCAATCATGATTAAAGCGACAACAGAACAACCACGCTATG
GAAATCCTACGCCTCGTGTTGCTGAAACACCGGGCGGCATGTTAAATGCAATCGGACTTCAAAACCCAGGATTAGAAAAA
GTAATGAATTCTGAATTACCATGGTTAGAACAATTTGATCTTCCAATCATTGCGAACGTTGCAGGCTCACAAGCTGAAGA
TTACGTAGCGGTTGCAAAGGAAATTTCTAAAGCGCCTAATGTTCATGCACTAGAATTAAACATTTCTTGTCCAAACGTAA
AAACAGGTGGTATCGCCTTTGGTACAAATCCTGAAATTGCTGCTGATTTAACGAAGCGAGTAAAAGAGGTTTCTGAAGTA
CCTGTATACGTGAAGTTGTCACCGAACGTGGCAAACATTGTAGAAATTGCAAAAGCGATTGCAAATGCAGGTGCAGATGG
TTTAACGATGATTAATACATTGCTTGGTATGCGTCTAGATTTAAAAACAGCTAAACCAATTTTAGCAAACCGTACAGGCG
GATTATCAGGTCCTGCGATTAAGCCAGTAGCAATTCGTATGGTACATGAAGTAAGCCAAGCGGTTAACATTCCAATTATC
GGAATGGGTGGTATTGAAACAGCGGAAGATGTAATCGAATTCTTCTACGCTGGCGCAAGCGCAGTTGCAGTAGGTACAGC
GAACTTTATCGATCCGTTCGTATGTCCGACAATTATTGAAGAGTTACCAGCATTACTAGATGAATTAGGATTTGATCACA
TTTCGGAATGCCAAGGAAGGAGCTGGAAGCAAACATGTCACAGTCGTTAA

Upstream 100 bases:

>100_bases
GTTTCGCATGTGTATGCCACTTACAAGAAGATCCAAGTGGACATTCTTACAAGAAGGTGTGTAGCGACGGACCAGTATTT
CCAATCGGGGAGGTTGTACT

Downstream 100 bases:

>100_bases
TCGTTGCACTAGATTTCCCAGGGAAACAAGATGTAGAACAATTCTTGCGCCACTTTGAAGGGGAAGAGTTATTTGTCAAA
GTTGGTATGGAGTTATTTTA

Product: dihydroorotate dehydrogenase 1B

Products: NA

Alternate protein names: DHOdehase; DHOD; DHODase; Dihydroorotate oxidase [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MNRLQVELPGLSLKNPIIPASGCFGFGREYAQFYDLSVLGSIMIKATTEQPRYGNPTPRVAETPGGMLNAIGLQNPGLEK
VMNSELPWLEQFDLPIIANVAGSQAEDYVAVAKEISKAPNVHALELNISCPNVKTGGIAFGTNPEIAADLTKRVKEVSEV
PVYVKLSPNVANIVEIAKAIANAGADGLTMINTLLGMRLDLKTAKPILANRTGGLSGPAIKPVAIRMVHEVSQAVNIPII
GMGGIETAEDVIEFFYAGASAVAVGTANFIDPFVCPTIIEELPALLDELGFDHISECQGRSWKQTCHSR

Sequences:

>Translated_309_residues
MNRLQVELPGLSLKNPIIPASGCFGFGREYAQFYDLSVLGSIMIKATTEQPRYGNPTPRVAETPGGMLNAIGLQNPGLEK
VMNSELPWLEQFDLPIIANVAGSQAEDYVAVAKEISKAPNVHALELNISCPNVKTGGIAFGTNPEIAADLTKRVKEVSEV
PVYVKLSPNVANIVEIAKAIANAGADGLTMINTLLGMRLDLKTAKPILANRTGGLSGPAIKPVAIRMVHEVSQAVNIPII
GMGGIETAEDVIEFFYAGASAVAVGTANFIDPFVCPTIIEELPALLDELGFDHISECQGRSWKQTCHSR
>Mature_309_residues
MNRLQVELPGLSLKNPIIPASGCFGFGREYAQFYDLSVLGSIMIKATTEQPRYGNPTPRVAETPGGMLNAIGLQNPGLEK
VMNSELPWLEQFDLPIIANVAGSQAEDYVAVAKEISKAPNVHALELNISCPNVKTGGIAFGTNPEIAADLTKRVKEVSEV
PVYVKLSPNVANIVEIAKAIANAGADGLTMINTLLGMRLDLKTAKPILANRTGGLSGPAIKPVAIRMVHEVSQAVNIPII
GMGGIETAEDVIEFFYAGASAVAVGTANFIDPFVCPTIIEELPALLDELGFDHISECQGRSWKQTCHSR

Specific function: Unknown

COG id: COG0167

COG function: function code F; Dihydroorotate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=344, Percent_Identity=30.2325581395349, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI45006951, Length=327, Percent_Identity=29.6636085626911, Blast_Score=106, Evalue=3e-23,
Organism=Escherichia coli, GI87082059, Length=317, Percent_Identity=28.7066246056782, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787177, Length=295, Percent_Identity=27.7966101694915, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71984108, Length=210, Percent_Identity=34.2857142857143, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17509475, Length=327, Percent_Identity=28.4403669724771, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322633, Length=305, Percent_Identity=27.5409836065574, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24640763, Length=222, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI18858217, Length=222, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI281361352, Length=324, Percent_Identity=29.320987654321, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI17137316, Length=324, Percent_Identity=29.320987654321, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005720
- InterPro:   IPR012135
- InterPro:   IPR001295 [H]

Pfam domain/function: PF01180 DHO_dh [H]

EC number: =1.3.3.1 [H]

Molecular weight: Translated: 32932; Mature: 32932

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00911 DHODEHASE_1 ; PS00912 DHODEHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLQVELPGLSLKNPIIPASGCFGFGREYAQFYDLSVLGSIMIKATTEQPRYGNPTPRV
CCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCC
AETPGGMLNAIGLQNPGLEKVMNSELPWLEQFDLPIIANVAGSQAEDYVAVAKEISKAPN
CCCCCCCEEECCCCCCCHHHHHCCCCCCHHHCCCCEEECCCCCCHHHHHHHHHHHHCCCC
VHALELNISCPNVKTGGIAFGTNPEIAADLTKRVKEVSEVPVYVKLSPNVANIVEIAKAI
EEEEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHH
ANAGADGLTMINTLLGMRLDLKTAKPILANRTGGLSGPAIKPVAIRMVHEVSQAVNIPII
HHCCCCHHHHHHHHHCCEECCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEE
GMGGIETAEDVIEFFYAGASAVAVGTANFIDPFVCPTIIEELPALLDELGFDHISECQGR
ECCCCCHHHHHHHHHHCCCHHEEECCHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCC
SWKQTCHSR
CHHHHHCCC
>Mature Secondary Structure
MNRLQVELPGLSLKNPIIPASGCFGFGREYAQFYDLSVLGSIMIKATTEQPRYGNPTPRV
CCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCC
AETPGGMLNAIGLQNPGLEKVMNSELPWLEQFDLPIIANVAGSQAEDYVAVAKEISKAPN
CCCCCCCEEECCCCCCCHHHHHCCCCCCHHHCCCCEEECCCCCCHHHHHHHHHHHHCCCC
VHALELNISCPNVKTGGIAFGTNPEIAADLTKRVKEVSEVPVYVKLSPNVANIVEIAKAI
EEEEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHH
ANAGADGLTMINTLLGMRLDLKTAKPILANRTGGLSGPAIKPVAIRMVHEVSQAVNIPII
HHCCCCHHHHHHHHHCCEECCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEE
GMGGIETAEDVIEFFYAGASAVAVGTANFIDPFVCPTIIEELPALLDELGFDHISECQGR
ECCCCCHHHHHHHHHHCCCHHEEECCHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCC
SWKQTCHSR
CHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA