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The map label for this gene is pyrF [H]

Identifier: 118479104

GI number: 118479104

Start: 3730811

End: 3731554

Strand: Reverse

Name: pyrF [H]

Synonym: BALH_3513

Alternate gene names: 118479104

Gene position: 3731554-3730811 (Counterclockwise)

Preceding gene: 118479105

Following gene: 118479103

Centisome position: 70.98

GC content: 40.99

Gene sequence:

>744_bases
ATGCCAAGGAAGGAGCTGGAAGCAAACATGTCACAGTCGTTAATCGTTGCACTAGATTTCCCAGGGAAACAAGATGTAGA
ACAATTCTTGCGCCACTTTGAAGGGGAAGAGTTATTTGTCAAAGTTGGTATGGAGTTATTTTACAAAGAAGGCCCTGCGA
TTATTACGTACTTAAAAGAAAAAGGACATAAAATCTTTCTAGATTTAAAACTTCATGATATTCCGAACACAGTAAAAAGC
GCTATGCGTAGCCTAGCTAGTCTAGATGTAGATATGGTAAATGTTCATGCTGCTGGGGGAAGCAGTATGATGAAAGCTGC
GATTGAGGGATTAGAGGAAGGTAAGCAAGAAGGAAAAGAGAGACCGATTTGTATTGCAGTTACACAACTAACCAGCACTT
CGGAAGCTATGATGAAAAAAGAGATCGGCATTGAGAAAACGTTAGAAGAAGCGGTTGCTCATTATGCAAAACTAACGAAA
GAAAGTGGACTTGATGGCGTTGTTTGCTCAACACTTGAAGTTCCAAAATTACGTGAAGTATGCGGAAATGAATTTGTAAC
AGTAACACCGGGGATTCGTCTTGCAAGCGATGATGTAAATGACCAGGTGCGCGTAGCAACACCGAAACGTGCGAGGGAAC
TTGGCTCAAGCTATATCGTAGTTGGACGTAGTATTACAAAAGCAGAAAATCCGCTTGAAGCGTATAAAACAGTAAAACAA
CAGTGGGAAGGTGTAACAGTATGA

Upstream 100 bases:

>100_bases
CAGTAGGTACAGCGAACTTTATCGATCCGTTCGTATGTCCGACAATTATTGAAGAGTTACCAGCATTACTAGATGAATTA
GGATTTGATCACATTTCGGA

Downstream 100 bases:

>100_bases
AAAAAGAAATAGCATCGCATTTATTAGAAATTGGAGCAGTATTTTTACAACCAAATGATCCATTCACATGGTCTTCAGGT
ATGAAATCACCAATTTATTG

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MPRKELEANMSQSLIVALDFPGKQDVEQFLRHFEGEELFVKVGMELFYKEGPAIITYLKEKGHKIFLDLKLHDIPNTVKS
AMRSLASLDVDMVNVHAAGGSSMMKAAIEGLEEGKQEGKERPICIAVTQLTSTSEAMMKKEIGIEKTLEEAVAHYAKLTK
ESGLDGVVCSTLEVPKLREVCGNEFVTVTPGIRLASDDVNDQVRVATPKRARELGSSYIVVGRSITKAENPLEAYKTVKQ
QWEGVTV

Sequences:

>Translated_247_residues
MPRKELEANMSQSLIVALDFPGKQDVEQFLRHFEGEELFVKVGMELFYKEGPAIITYLKEKGHKIFLDLKLHDIPNTVKS
AMRSLASLDVDMVNVHAAGGSSMMKAAIEGLEEGKQEGKERPICIAVTQLTSTSEAMMKKEIGIEKTLEEAVAHYAKLTK
ESGLDGVVCSTLEVPKLREVCGNEFVTVTPGIRLASDDVNDQVRVATPKRARELGSSYIVVGRSITKAENPLEAYKTVKQ
QWEGVTV
>Mature_246_residues
PRKELEANMSQSLIVALDFPGKQDVEQFLRHFEGEELFVKVGMELFYKEGPAIITYLKEKGHKIFLDLKLHDIPNTVKSA
MRSLASLDVDMVNVHAAGGSSMMKAAIEGLEEGKQEGKERPICIAVTQLTSTSEAMMKKEIGIEKTLEEAVAHYAKLTKE
SGLDGVVCSTLEVPKLREVCGNEFVTVTPGIRLASDDVNDQVRVATPKRARELGSSYIVVGRSITKAENPLEAYKTVKQQ
WEGVTV

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787537, Length=226, Percent_Identity=41.5929203539823, Blast_Score=169, Evalue=2e-43,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR018089
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 27268; Mature: 27137

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00156 OMPDECASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRKELEANMSQSLIVALDFPGKQDVEQFLRHFEGEELFVKVGMELFYKEGPAIITYLKE
CCHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCEEEEEEHH
KGHKIFLDLKLHDIPNTVKSAMRSLASLDVDMVNVHAAGGSSMMKAAIEGLEEGKQEGKE
CCCEEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCC
RPICIAVTQLTSTSEAMMKKEIGIEKTLEEAVAHYAKLTKESGLDGVVCSTLEVPKLREV
CCEEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHH
CGNEFVTVTPGIRLASDDVNDQVRVATPKRARELGSSYIVVGRSITKAENPLEAYKTVKQ
HCCCEEEECCCCEEECCCCCCCEEEECCHHHHHCCCCEEEECCCHHHCCCHHHHHHHHHH
QWEGVTV
HCCCCCC
>Mature Secondary Structure 
PRKELEANMSQSLIVALDFPGKQDVEQFLRHFEGEELFVKVGMELFYKEGPAIITYLKE
CHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCEEEEEEHH
KGHKIFLDLKLHDIPNTVKSAMRSLASLDVDMVNVHAAGGSSMMKAAIEGLEEGKQEGKE
CCCEEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCC
RPICIAVTQLTSTSEAMMKKEIGIEKTLEEAVAHYAKLTKESGLDGVVCSTLEVPKLREV
CCEEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHH
CGNEFVTVTPGIRLASDDVNDQVRVATPKRARELGSSYIVVGRSITKAENPLEAYKTVKQ
HCCCEEEECCCCEEECCCCCCCEEEECCHHHHHCCCCEEEECCCHHHCCCHHHHHHHHHH
QWEGVTV
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA