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The map label for this gene is mhqO [H]

Identifier: 118478880

GI number: 118478880

Start: 3474818

End: 3475765

Strand: Reverse

Name: mhqO [H]

Synonym: BALH_3279

Alternate gene names: 118478880

Gene position: 3475765-3474818 (Counterclockwise)

Preceding gene: 118478881

Following gene: 118478879

Centisome position: 66.12

GC content: 37.97

Gene sequence:

>948_bases
GTGGAGAAAATGGAAAAGAAAACAATGGGAATTCATCACATTACAGCAATCGTAGGACATCCACAAGAAAATGTAGATTT
TTATGCTGGTGTATTAGGGTTACGTTTAGTGAAACAAACAGTGAATTTTGATGATCCAGGTACGTACCATCTTTATTTCG
GTAATGAAGCAGGGAAGCCAGGAACAATCATTACGTTTTTCCCATGGGCAGGTGCTCGTCAAGGAATTATTGGTGACGGT
CAAGTAGGAATCACTTCTTATGTTGTACCAAAAGGGGCAATGAAATTTTGGGAAAATAGATTAGAAAAATTCGATGTTTC
GTATACAAAAATGACTCGATTTGGAGAGCAGTATTTAGAATTTGATGATCCACATGGTTTGCATATAGAATTAGTAGAAA
GAGAAGAAGGCGAATTAAATAATTGGAGCTTTGGGGAAGTTACGCCAGAAGTAGCAATTAAAGGATTTGGTGGTGCTGTT
CTTTTATCAGCGCACCCTCAAAAAACTGCTGAATTGTTAGAGCACGTTATGGGTCTTGAGAAAATTGGGGAAGAGGGCGA
ATTTGTTCGATTCCGTTCTTCTGCTGATATTGGAAATATTATTGATTTGAAATTATCGACAATTGGACGTGGCCAGATGG
GTGTTGGTACAGTCCATCATATTGCTTGGAGAGCGAGTGATGATGCTGATCAGTTAGACTGGAAAGAGCACGTATCCCGT
TTTGGATACCACGTAACTCCTGTACAAGACCGAAATTATTTTAACGCGATTTATTTTAGAGAACACGGTGAAATTTTATT
TGAAATTGCAACAGATCCTCCTGGTTTCGCTCATGATGAATCGTTAGAGACGATGGGTGAGGAATTAAAGTTACCGGAAC
AATATGAACAACATAGAAAACAGATTGAACAAACACTTTTACCATTTGAAGTGAGAAATTTAGATTAA

Upstream 100 bases:

>100_bases
TCGAGATGAAATTATCATGACGGATTTTACTTTCTAGTATGGACAAAATGAATAATGAATTTTAATGTAAAAAATTTTTT
CATAATGAATTAAAAAAGGA

Downstream 100 bases:

>100_bases
AGTGATTGAAAGGGGAAAAGGATTATGATGAAACATGTTTTTCAAAAAGGAAAAGATACGTCAAAACCAGTATTGCTATT
ACTTCATGGTACAGGAGGTA

Product: glyoxalase/bleomycin resistance protein

Products: glutathione; methylglyoxal

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MEKMEKKTMGIHHITAIVGHPQENVDFYAGVLGLRLVKQTVNFDDPGTYHLYFGNEAGKPGTIITFFPWAGARQGIIGDG
QVGITSYVVPKGAMKFWENRLEKFDVSYTKMTRFGEQYLEFDDPHGLHIELVEREEGELNNWSFGEVTPEVAIKGFGGAV
LLSAHPQKTAELLEHVMGLEKIGEEGEFVRFRSSADIGNIIDLKLSTIGRGQMGVGTVHHIAWRASDDADQLDWKEHVSR
FGYHVTPVQDRNYFNAIYFREHGEILFEIATDPPGFAHDESLETMGEELKLPEQYEQHRKQIEQTLLPFEVRNLD

Sequences:

>Translated_315_residues
MEKMEKKTMGIHHITAIVGHPQENVDFYAGVLGLRLVKQTVNFDDPGTYHLYFGNEAGKPGTIITFFPWAGARQGIIGDG
QVGITSYVVPKGAMKFWENRLEKFDVSYTKMTRFGEQYLEFDDPHGLHIELVEREEGELNNWSFGEVTPEVAIKGFGGAV
LLSAHPQKTAELLEHVMGLEKIGEEGEFVRFRSSADIGNIIDLKLSTIGRGQMGVGTVHHIAWRASDDADQLDWKEHVSR
FGYHVTPVQDRNYFNAIYFREHGEILFEIATDPPGFAHDESLETMGEELKLPEQYEQHRKQIEQTLLPFEVRNLD
>Mature_315_residues
MEKMEKKTMGIHHITAIVGHPQENVDFYAGVLGLRLVKQTVNFDDPGTYHLYFGNEAGKPGTIITFFPWAGARQGIIGDG
QVGITSYVVPKGAMKFWENRLEKFDVSYTKMTRFGEQYLEFDDPHGLHIELVEREEGELNNWSFGEVTPEVAIKGFGGAV
LLSAHPQKTAELLEHVMGLEKIGEEGEFVRFRSSADIGNIIDLKLSTIGRGQMGVGTVHHIAWRASDDADQLDWKEHVSR
FGYHVTPVQDRNYFNAIYFREHGEILFEIATDPPGFAHDESLETMGEELKLPEQYEQHRKQIEQTLLPFEVRNLD

Specific function: Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds (Potential) [H]

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the extradiol ring-cleavage dioxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 35750; Mature: 35750

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKMEKKTMGIHHITAIVGHPQENVDFYAGVLGLRLVKQTVNFDDPGTYHLYFGNEAGKP
CCCHHHHHCCHHHEEHEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCC
GTIITFFPWAGARQGIIGDGQVGITSYVVPKGAMKFWENRLEKFDVSYTKMTRFGEQYLE
CEEEEEECCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
FDDPHGLHIELVEREEGELNNWSFGEVTPEVAIKGFGGAVLLSAHPQKTAELLEHVMGLE
CCCCCCCEEEEEECCCCCCCCCCCCCCCHHHEEECCCCEEEEECCCHHHHHHHHHHHHHH
KIGEEGEFVRFRSSADIGNIIDLKLSTIGRGQMGVGTVHHIAWRASDDADQLDWKEHVSR
HHCCCCCEEEEECCCCCCCEEEEEEEECCCCCCCCCHHHHEEEECCCCCCCCCHHHHHHH
FGYHVTPVQDRNYFNAIYFREHGEILFEIATDPPGFAHDESLETMGEELKLPEQYEQHRK
CCCEECEECCCCCEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHH
QIEQTLLPFEVRNLD
HHHHHHCCEEECCCC
>Mature Secondary Structure
MEKMEKKTMGIHHITAIVGHPQENVDFYAGVLGLRLVKQTVNFDDPGTYHLYFGNEAGKP
CCCHHHHHCCHHHEEHEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCC
GTIITFFPWAGARQGIIGDGQVGITSYVVPKGAMKFWENRLEKFDVSYTKMTRFGEQYLE
CEEEEEECCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
FDDPHGLHIELVEREEGELNNWSFGEVTPEVAIKGFGGAVLLSAHPQKTAELLEHVMGLE
CCCCCCCEEEEEECCCCCCCCCCCCCCCHHHEEECCCCEEEEECCCHHHHHHHHHHHHHH
KIGEEGEFVRFRSSADIGNIIDLKLSTIGRGQMGVGTVHHIAWRASDDADQLDWKEHVSR
HHCCCCCEEEEECCCCCCCEEEEEEEECCCCCCCCCHHHHEEEECCCCCCCCCHHHHHHH
FGYHVTPVQDRNYFNAIYFREHGEILFEIATDPPGFAHDESLETMGEELKLPEQYEQHRK
CCCEECEECCCCCEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHH
QIEQTLLPFEVRNLD
HHHHHHCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]