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The map label for this gene is dhbB [H]

Identifier: 118478563

GI number: 118478563

Start: 3125498

End: 3126079

Strand: Reverse

Name: dhbB [H]

Synonym: BALH_2939

Alternate gene names: 118478563

Gene position: 3126079-3125498 (Counterclockwise)

Preceding gene: 118478564

Following gene: 118478562

Centisome position: 59.46

GC content: 33.51

Gene sequence:

>582_bases
ATGAAATATGCAGTGCTTACAAATGACTTACAGTACGATTTGGTTAATAAAAATGAGGATAGAATTGCAGCTGTGGAGGA
GTTTACACCTAAAATGGTGTCTTTCTTAAATACTATGAGAGAAAATGATGTTTCTATTGTTCACCTACAGTTAATTAACT
TAGAAGATGATCCGAAAGCTGAACGATATGGTGATTTTTTACCAGTCACAAAGGGATCTAAAGGTGCAGAAATCTTACCT
GAGTTTCTTCATGAAACAGATATTATTATGGAGAAAAATAAGGATAGTGGTTTTTTTGAGACAAATCTAGATGAAACCTT
AAAAAAATTAGGAGTAGATACAATTATTATTACGGGTATGCAAACTCAAATTTGCGTACAAACAACTGCAGCAGATGGAT
TTTTCCGTGGTTATAATGTAATCGTACCAGAAGATGCGGTTGTTTCAGCGAAGGCTGAAGATAAAGAACGCGCTTTAAAA
TGGTTAGGTTCATATTGTGCAAAGATTATGAGTATCGAGGAAATTTGCAATTCGATTTCTAAAAATGAAGATATTTCTTT
TGATGGAGTTGCAATTCCGTAA

Upstream 100 bases:

>100_bases
AGATAAAAAATAATATTTGACATATTCTTACTACTGGTGGAATAATGAACATTGTATTTTAGAAAAATTAAATTCTTAGT
TAATTGGAGGTAGGATTATT

Downstream 100 bases:

>100_bases
GTAAATACGTTGTAATATCACTTGTTCTATGTAGCAAGTGATATTATTTTTCAAAAATAAAAATAAAAAGGAGTTTTAAC
AAATGAAATTAACTAAAGAT

Product: isochorismatase

Products: NA

Alternate protein names: Ureidoacrylate amidohydrolase [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MKYAVLTNDLQYDLVNKNEDRIAAVEEFTPKMVSFLNTMRENDVSIVHLQLINLEDDPKAERYGDFLPVTKGSKGAEILP
EFLHETDIIMEKNKDSGFFETNLDETLKKLGVDTIIITGMQTQICVQTTAADGFFRGYNVIVPEDAVVSAKAEDKERALK
WLGSYCAKIMSIEEICNSISKNEDISFDGVAIP

Sequences:

>Translated_193_residues
MKYAVLTNDLQYDLVNKNEDRIAAVEEFTPKMVSFLNTMRENDVSIVHLQLINLEDDPKAERYGDFLPVTKGSKGAEILP
EFLHETDIIMEKNKDSGFFETNLDETLKKLGVDTIIITGMQTQICVQTTAADGFFRGYNVIVPEDAVVSAKAEDKERALK
WLGSYCAKIMSIEEICNSISKNEDISFDGVAIP
>Mature_193_residues
MKYAVLTNDLQYDLVNKNEDRIAAVEEFTPKMVSFLNTMRENDVSIVHLQLINLEDDPKAERYGDFLPVTKGSKGAEILP
EFLHETDIIMEKNKDSGFFETNLDETLKKLGVDTIIITGMQTQICVQTTAADGFFRGYNVIVPEDAVVSAKAEDKERALK
WLGSYCAKIMSIEEICNSISKNEDISFDGVAIP

Specific function: In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby rele

COG id: COG1335

COG function: function code Q; Amidases related to nicotinamidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismatase family. RutB subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081992, Length=113, Percent_Identity=31.858407079646, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI87081820, Length=117, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019916
- InterPro:   IPR000868 [H]

Pfam domain/function: PF00857 Isochorismatase [H]

EC number: NA

Molecular weight: Translated: 21651; Mature: 21651

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYAVLTNDLQYDLVNKNEDRIAAVEEFTPKMVSFLNTMRENDVSIVHLQLINLEDDPKA
CCEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCH
ERYGDFLPVTKGSKGAEILPEFLHETDIIMEKNKDSGFFETNLDETLKKLGVDTIIITGM
HHCCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCCCCEECCHHHHHHHHCCCEEEEECC
QTQICVQTTAADGFFRGYNVIVPEDAVVSAKAEDKERALKWLGSYCAKIMSIEEICNSIS
CCEEEEEECCCCCCCCCCEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KNEDISFDGVAIP
CCCCCCCCCEECC
>Mature Secondary Structure
MKYAVLTNDLQYDLVNKNEDRIAAVEEFTPKMVSFLNTMRENDVSIVHLQLINLEDDPKA
CCEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCH
ERYGDFLPVTKGSKGAEILPEFLHETDIIMEKNKDSGFFETNLDETLKKLGVDTIIITGM
HHCCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCCCCEECCHHHHHHHHCCCEEEEECC
QTQICVQTTAADGFFRGYNVIVPEDAVVSAKAEDKERALKWLGSYCAKIMSIEEICNSIS
CCEEEEEECCCCCCCCCCEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KNEDISFDGVAIP
CCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA