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The map label for this gene is phoP [H]

Identifier: 118478209

GI number: 118478209

Start: 2728215

End: 2728862

Strand: Reverse

Name: phoP [H]

Synonym: BALH_2567

Alternate gene names: 118478209

Gene position: 2728862-2728215 (Counterclockwise)

Preceding gene: 118478211

Following gene: 118478208

Centisome position: 51.91

GC content: 32.87

Gene sequence:

>648_bases
ATGAAAGTATTAATCGCAGATGATGAACAAGATATGCTAAGGATTTTAAAAGCTTATTTTGAGAAAGAAGGCTTCGAAGT
TTTCTTAGCGAAAGATGGAGAAGAAGCACTTCAAATATTTTATGATGAAAAAATTGATTTAGCTATTTTAGATTGGATGA
TGCCGAAACATAGCGGTATTACTGTTTGTCAGGAAATAAAGAAAAACTCAAGCGTAAAAGTATTAATGCTCACGGCGAAA
AGTGAAAGCGAAGATGAATTAGCAGCTCTTCAAAGCGGGGCAGATGAGTACGTAAAAAAACCATTTCATCCAGGTGTACT
CATTACTCGAGCGAAAAAGCTAATACAGCACGATGATGTCATTCAAGTTCAAGATTTGAAAATTGATTTTACGAAAAATA
AAGTTTATAAAAATGACAAGGAATTAGATATTACAAAAACAGAGCTAGAATTAATAAAATGTTTTTTAAACCATAAAGGG
ATGATTTTAACTCGTAAAAAATTGTTAGATATCGTATGGGGATTTGACTATTTTGGAGAAGAGCGAACTGTTGATACACA
TGTAAGGAGATTACGAAAAAAAGTTGGAGAAAATATTATAAAGACGCACCGCGGGCTAGGATATAGTTTGGAGGAACAGA
GTGAATAA

Upstream 100 bases:

>100_bases
TATACCCTTAACTGGTTCAAATATTTTTCTGTCACATACATGTAACAAAGAAGTTGTATGATACAATTGATTTTTGTTTA
AAAGCAATGGAGGATAATGT

Downstream 100 bases:

>100_bases
ACTTGGAAAAAAGCTATTTCTTAGTATATCTTTAACCGTTATTCTTATATTTACGATCTCTTTATTATTAATTAACTATC
TTTTACCGAAATATAATATT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKVLIADDEQDMLRILKAYFEKEGFEVFLAKDGEEALQIFYDEKIDLAILDWMMPKHSGITVCQEIKKNSSVKVLMLTAK
SESEDELAALQSGADEYVKKPFHPGVLITRAKKLIQHDDVIQVQDLKIDFTKNKVYKNDKELDITKTELELIKCFLNHKG
MILTRKKLLDIVWGFDYFGEERTVDTHVRRLRKKVGENIIKTHRGLGYSLEEQSE

Sequences:

>Translated_215_residues
MKVLIADDEQDMLRILKAYFEKEGFEVFLAKDGEEALQIFYDEKIDLAILDWMMPKHSGITVCQEIKKNSSVKVLMLTAK
SESEDELAALQSGADEYVKKPFHPGVLITRAKKLIQHDDVIQVQDLKIDFTKNKVYKNDKELDITKTELELIKCFLNHKG
MILTRKKLLDIVWGFDYFGEERTVDTHVRRLRKKVGENIIKTHRGLGYSLEEQSE
>Mature_215_residues
MKVLIADDEQDMLRILKAYFEKEGFEVFLAKDGEEALQIFYDEKIDLAILDWMMPKHSGITVCQEIKKNSSVKVLMLTAK
SESEDELAALQSGADEYVKKPFHPGVLITRAKKLIQHDDVIQVQDLKIDFTKNKVYKNDKELDITKTELELIKCFLNHKG
MILTRKKLLDIVWGFDYFGEERTVDTHVRRLRKKVGENIIKTHRGLGYSLEEQSE

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=34.5454545454545, Blast_Score=150, Evalue=5e-38,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=28.8888888888889, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=31.0502283105023, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=33.9366515837104, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=31.5315315315315, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=30.1801801801802, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=28.8990825688073, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787229, Length=221, Percent_Identity=26.6968325791855, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=31.2775330396476, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=30.6666666666667, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=27.6018099547511, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=29.4642857142857, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=26.7543859649123, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=26.4840182648402, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1788550, Length=102, Percent_Identity=37.2549019607843, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=34.1666666666667, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790437, Length=101, Percent_Identity=35.6435643564356, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24964; Mature: 24964

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLIADDEQDMLRILKAYFEKEGFEVFLAKDGEEALQIFYDEKIDLAILDWMMPKHSGI
CEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCEEHHHHHCCCCCCH
TVCQEIKKNSSVKVLMLTAKSESEDELAALQSGADEYVKKPFHPGVLITRAKKLIQHDDV
HHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHCCCCC
IQVQDLKIDFTKNKVYKNDKELDITKTELELIKCFLNHKGMILTRKKLLDIVWGFDYFGE
EEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCHHHCCC
ERTVDTHVRRLRKKVGENIIKTHRGLGYSLEEQSE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKVLIADDEQDMLRILKAYFEKEGFEVFLAKDGEEALQIFYDEKIDLAILDWMMPKHSGI
CEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCEEHHHHHCCCCCCH
TVCQEIKKNSSVKVLMLTAKSESEDELAALQSGADEYVKKPFHPGVLITRAKKLIQHDDV
HHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHCCCCC
IQVQDLKIDFTKNKVYKNDKELDITKTELELIKCFLNHKGMILTRKKLLDIVWGFDYFGE
EEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCHHHCCC
ERTVDTHVRRLRKKVGENIIKTHRGLGYSLEEQSE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]