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The map label for this gene is pcoS [H]

Identifier: 118478208

GI number: 118478208

Start: 2726846

End: 2728222

Strand: Reverse

Name: pcoS [H]

Synonym: BALH_2566

Alternate gene names: 118478208

Gene position: 2728222-2726846 (Counterclockwise)

Preceding gene: 118478209

Following gene: 118478207

Centisome position: 51.9

GC content: 29.77

Gene sequence:

>1377_bases
GTGAATAAACTTGGAAAAAAGCTATTTCTTAGTATATCTTTAACCGTTATTCTTATATTTACGATCTCTTTATTATTAAT
TAACTATCTTTTACCGAAATATAATATTTACAAAACACGAGAAAGCTTAGAAGGTATTACAGCGCAAATTCAGTCCATAC
CGAGAGAACAATTGGATGAAGCAATTACGAGCATTGAAAATGAGGGGAATGTTACGATTGCGTATACATCCATAAAAGAC
TCAGAAGATCATATTAATGATGAGTTACGTATGCAACTTACAAAAAAGAGAGTTGCCCTTAATAAAATTTGGATTACAAA
AGAAGAAATAATGAAAGTAAAGAAATTCGGACATTCGAATAAAATATATGATCAAGAGAAAATCAAATCCAGTTTTTTTG
TGAAATACATGGCGAAGGATGATATGTTGATTTTAGTAGGAGTTTCTATCGCACATTCAAATGAAATAATAAAAACGTTA
AACTCATTTTATTTATTCATTTTAGTTATTACGATTTTTCTCATTATCGTACTTGTATGGATATTGTCAAAAACAATTAC
GACACCGCTGAAAGAATTAAGTGATGTCGCAGAAGATATTTCACGTTTACAGTTTAAAAAGACAAAAGTGAAAACGAATG
ATGAAATAGGAGACTTAGCTACTAGTATTAATATCATGAGTGAAAAACTACAGGAAGCGCATCAAGATTTAACAGATCGT
AATGAACATTTAAAACGATTTATGGGTGATGTGACCCATGAATTAAAAACTCCAATCGCGTTAGTGAAAGCATATTCTAT
GGGAATAAAAGATGGTCTAGATGATGGTACATACATAGATACAATCATTAAACAATCGGATCACATATCAAACTTAATTG
AAGAGTTATTACGATTTTCTAAACTAGAAAGAGATGTGTTACAAAAAGAAGAATTCTCTATTAAATCACTAGTCCAAAGT
ATATTAGATAAGCATAAGATTGAACTGGAGTCGAAAGAAATTAATTTGCAAGTGAACTATAATGTTGGCGATGCAATTGT
TTATGCAGATGTAAATAAAATGAGAATGGTGTTCCAAAATTTAATTTCTAATGCGATAAAATATACATCAAATCAAAATA
TAAAAATTACATTAGAAGATCGAAATGAGAGTGTATATTTTCAAATTCAAAATGGTATGAATGCTGAACATATGAAAGAT
ATCGATAAAATTTGGGAACCTTTTTACGTCTTAGAATCTTCTCGTAGTAAAGATCATTCAGGTACAGGACTAGGCTTAGC
GATCGTGAAAAGTATTTTAGAAAGACATGGTTTTGACTATGGCGTATTTACTATAGGGGGAGAAATACGATTTTATATAA
ATTTGAGGAATGAGTAA

Upstream 100 bases:

>100_bases
GAGCGAACTGTTGATACACATGTAAGGAGATTACGAAAAAAAGTTGGAGAAAATATTATAAAGACGCACCGCGGGCTAGG
ATATAGTTTGGAGGAACAGA

Downstream 100 bases:

>100_bases
TTCAATACTAGTAGAAGCATCGTCTATTAATAGGCGATGTTTTTTATAGTAGTAAGTCAGAATGTATAATATTGGAAGAG
TGTTCTACAAATTTCTCAAG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MNKLGKKLFLSISLTVILIFTISLLLINYLLPKYNIYKTRESLEGITAQIQSIPREQLDEAITSIENEGNVTIAYTSIKD
SEDHINDELRMQLTKKRVALNKIWITKEEIMKVKKFGHSNKIYDQEKIKSSFFVKYMAKDDMLILVGVSIAHSNEIIKTL
NSFYLFILVITIFLIIVLVWILSKTITTPLKELSDVAEDISRLQFKKTKVKTNDEIGDLATSINIMSEKLQEAHQDLTDR
NEHLKRFMGDVTHELKTPIALVKAYSMGIKDGLDDGTYIDTIIKQSDHISNLIEELLRFSKLERDVLQKEEFSIKSLVQS
ILDKHKIELESKEINLQVNYNVGDAIVYADVNKMRMVFQNLISNAIKYTSNQNIKITLEDRNESVYFQIQNGMNAEHMKD
IDKIWEPFYVLESSRSKDHSGTGLGLAIVKSILERHGFDYGVFTIGGEIRFYINLRNE

Sequences:

>Translated_458_residues
MNKLGKKLFLSISLTVILIFTISLLLINYLLPKYNIYKTRESLEGITAQIQSIPREQLDEAITSIENEGNVTIAYTSIKD
SEDHINDELRMQLTKKRVALNKIWITKEEIMKVKKFGHSNKIYDQEKIKSSFFVKYMAKDDMLILVGVSIAHSNEIIKTL
NSFYLFILVITIFLIIVLVWILSKTITTPLKELSDVAEDISRLQFKKTKVKTNDEIGDLATSINIMSEKLQEAHQDLTDR
NEHLKRFMGDVTHELKTPIALVKAYSMGIKDGLDDGTYIDTIIKQSDHISNLIEELLRFSKLERDVLQKEEFSIKSLVQS
ILDKHKIELESKEINLQVNYNVGDAIVYADVNKMRMVFQNLISNAIKYTSNQNIKITLEDRNESVYFQIQNGMNAEHMKD
IDKIWEPFYVLESSRSKDHSGTGLGLAIVKSILERHGFDYGVFTIGGEIRFYINLRNE
>Mature_458_residues
MNKLGKKLFLSISLTVILIFTISLLLINYLLPKYNIYKTRESLEGITAQIQSIPREQLDEAITSIENEGNVTIAYTSIKD
SEDHINDELRMQLTKKRVALNKIWITKEEIMKVKKFGHSNKIYDQEKIKSSFFVKYMAKDDMLILVGVSIAHSNEIIKTL
NSFYLFILVITIFLIIVLVWILSKTITTPLKELSDVAEDISRLQFKKTKVKTNDEIGDLATSINIMSEKLQEAHQDLTDR
NEHLKRFMGDVTHELKTPIALVKAYSMGIKDGLDDGTYIDTIIKQSDHISNLIEELLRFSKLERDVLQKEEFSIKSLVQS
ILDKHKIELESKEINLQVNYNVGDAIVYADVNKMRMVFQNLISNAIKYTSNQNIKITLEDRNESVYFQIQNGMNAEHMKD
IDKIWEPFYVLESSRSKDHSGTGLGLAIVKSILERHGFDYGVFTIGGEIRFYINLRNE

Specific function: Probable member of a two-component regulatory system pcoS/pcoR. May activate pcoR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=261, Percent_Identity=26.4367816091954, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1789149, Length=338, Percent_Identity=24.2603550295858, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790346, Length=193, Percent_Identity=24.3523316062176, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788279, Length=282, Percent_Identity=28.7234042553192, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786783, Length=321, Percent_Identity=24.6105919003115, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790861, Length=351, Percent_Identity=23.3618233618234, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI145693157, Length=217, Percent_Identity=26.2672811059908, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786600, Length=218, Percent_Identity=24.7706422018349, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082128, Length=301, Percent_Identity=23.2558139534884, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790551, Length=302, Percent_Identity=25.8278145695364, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=24.537037037037, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI48994928, Length=224, Percent_Identity=23.6607142857143, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788549, Length=254, Percent_Identity=22.4409448818898, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR006290
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52745; Mature: 52745

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLGKKLFLSISLTVILIFTISLLLINYLLPKYNIYKTRESLEGITAQIQSIPREQLDE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHH
AITSIENEGNVTIAYTSIKDSEDHINDELRMQLTKKRVALNKIWITKEEIMKVKKFGHSN
HHHHCCCCCCEEEEEEECCCCHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
KIYDQEKIKSSFFVKYMAKDDMLILVGVSIAHSNEIIKTLNSFYLFILVITIFLIIVLVW
CCCCHHHHHHHHHHHEECCCCEEEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSKTITTPLKELSDVAEDISRLQFKKTKVKTNDEIGDLATSINIMSEKLQEAHQDLTDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCH
NEHLKRFMGDVTHELKTPIALVKAYSMGIKDGLDDGTYIDTIIKQSDHISNLIEELLRFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHH
KLERDVLQKEEFSIKSLVQSILDKHKIELESKEINLQVNYNVGDAIVYADVNKMRMVFQN
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCEEEEEEEECCCCEEEEECHHHHHHHHHH
LISNAIKYTSNQNIKITLEDRNESVYFQIQNGMNAEHMKDIDKIWEPFYVLESSRSKDHS
HHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCCC
GTGLGLAIVKSILERHGFDYGVFTIGGEIRFYINLRNE
CCCHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEECCC
>Mature Secondary Structure
MNKLGKKLFLSISLTVILIFTISLLLINYLLPKYNIYKTRESLEGITAQIQSIPREQLDE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHH
AITSIENEGNVTIAYTSIKDSEDHINDELRMQLTKKRVALNKIWITKEEIMKVKKFGHSN
HHHHCCCCCCEEEEEEECCCCHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
KIYDQEKIKSSFFVKYMAKDDMLILVGVSIAHSNEIIKTLNSFYLFILVITIFLIIVLVW
CCCCHHHHHHHHHHHEECCCCEEEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSKTITTPLKELSDVAEDISRLQFKKTKVKTNDEIGDLATSINIMSEKLQEAHQDLTDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCH
NEHLKRFMGDVTHELKTPIALVKAYSMGIKDGLDDGTYIDTIIKQSDHISNLIEELLRFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHH
KLERDVLQKEEFSIKSLVQSILDKHKIELESKEINLQVNYNVGDAIVYADVNKMRMVFQN
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCEEEEEEEECCCCEEEEECHHHHHHHHHH
LISNAIKYTSNQNIKITLEDRNESVYFQIQNGMNAEHMKDIDKIWEPFYVLESSRSKDHS
HHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCCC
GTGLGLAIVKSILERHGFDYGVFTIGGEIRFYINLRNE
CCCHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8594334 [H]