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The map label for this gene is aroB [H]

Identifier: 118477070

GI number: 118477070

Start: 1512380

End: 1513471

Strand: Direct

Name: aroB [H]

Synonym: BALH_1371

Alternate gene names: 118477070

Gene position: 1512380-1513471 (Clockwise)

Preceding gene: 118477069

Following gene: 118477071

Centisome position: 28.77

GC content: 37.73

Gene sequence:

>1092_bases
ATGGGAAACATACATATTCAAACGAAATCAAAAGAATATGATGTATATGTAGGAAAAGAATCGTTGTCACATTTGACAAC
AATCGTTCAAAACATGCAGCCATCTGTATCAAATATTATGATCATTTCAGATGAAGCTGTTGCATCTTTACATTTACAGA
CAGTTGTAGACGCGTTGCAAATAGATCAAAAAGTATTTTCATTCGTTGTACCGAGCGGTGAAAAAGAGAAGTCCTTTGAA
AATTTCTATGCGGCTCATACGTCAGCTCTTGAAAATAAATTAGATAGAAATTCTTTAATTGTTGCACTTGGAGGTGGGAT
GATTGGAGATTTAGCTGGTTTTGTTGCTGCGTCGTTTATGCGTGGAATTCGCTTTGTTCAAGTTCCGACGACTTTATTAG
CTCACGATAGCGCGGTAGGTGGGAAAGTAGCAATCAATCATCCGTTAGGTAAAAATATGATAGGTGCATTCCATCAACCG
GAAGCAGTTGTATATCATACGCCATTTTTACAGTCTCTTCCTGAAAAAGAGTGGCGCTCAGGTTATGCAGAAGTGATAAA
ACATGCTCTAATTGGTGATGTAAAGCTATATCATTGGCTAAAAGAAGAAGTGCAAACATTAGCAGATCTTCGTGATGAGA
AATTAATCCATATATTAACGAAGGCAATTCCTGTAAAGGCAAACATTGTAGCACAAGATGAAACAGAAAAAGGTGTACGT
GCTCATTTGAACTTTGGACATACGTTAGGCCATGCTCTTGAAAAAGAACTAGGATATGGAAATATTACTCACGGTGACGG
AGTAGCGGTTGGAATGTTATTTGCTATATTCTTAAGTGAACAAGTGTATAAGGTGAATCTTGCTTATGAAGAGATGAAGC
AGTGGTTCTTGAAGTACGGCTATCCCAAAATGCCAAGTGATTTAAGTGTAGAACGCCTCGTCGGGTTGATGAAACAAGAT
AAGAAAGCGAATGCAGGGACAATTCATATGGTACTTATGCAGGAATATGGGGTAGTGAATGTCGTATCTATTCCTGATGA
GACTGTTCATATTGCGTTAGAGGCATTTCAAAAGGATATGGTTGAAAAATAA

Upstream 100 bases:

>100_bases
GGGAATTAGCGACAGCTTTAATAGAACAATTCGGATTAGATCGTATGGACCTTATTCGTGAAAATATTGAGAAACATAAT
GAATATGCGAGGGGATTTTA

Downstream 100 bases:

>100_bases
ATGATAAAGAGTAGCCATGAAGTGCTTATTTTGAGGTGTTTTCGTAATAGTGACGGTTAGGATAAAAGATTACAGTAAAG
GGCTAAAATTGTATTGTAAT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MGNIHIQTKSKEYDVYVGKESLSHLTTIVQNMQPSVSNIMIISDEAVASLHLQTVVDALQIDQKVFSFVVPSGEKEKSFE
NFYAAHTSALENKLDRNSLIVALGGGMIGDLAGFVAASFMRGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQP
EAVVYHTPFLQSLPEKEWRSGYAEVIKHALIGDVKLYHWLKEEVQTLADLRDEKLIHILTKAIPVKANIVAQDETEKGVR
AHLNFGHTLGHALEKELGYGNITHGDGVAVGMLFAIFLSEQVYKVNLAYEEMKQWFLKYGYPKMPSDLSVERLVGLMKQD
KKANAGTIHMVLMQEYGVVNVVSIPDETVHIALEAFQKDMVEK

Sequences:

>Translated_363_residues
MGNIHIQTKSKEYDVYVGKESLSHLTTIVQNMQPSVSNIMIISDEAVASLHLQTVVDALQIDQKVFSFVVPSGEKEKSFE
NFYAAHTSALENKLDRNSLIVALGGGMIGDLAGFVAASFMRGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQP
EAVVYHTPFLQSLPEKEWRSGYAEVIKHALIGDVKLYHWLKEEVQTLADLRDEKLIHILTKAIPVKANIVAQDETEKGVR
AHLNFGHTLGHALEKELGYGNITHGDGVAVGMLFAIFLSEQVYKVNLAYEEMKQWFLKYGYPKMPSDLSVERLVGLMKQD
KKANAGTIHMVLMQEYGVVNVVSIPDETVHIALEAFQKDMVEK
>Mature_362_residues
GNIHIQTKSKEYDVYVGKESLSHLTTIVQNMQPSVSNIMIISDEAVASLHLQTVVDALQIDQKVFSFVVPSGEKEKSFEN
FYAAHTSALENKLDRNSLIVALGGGMIGDLAGFVAASFMRGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQPE
AVVYHTPFLQSLPEKEWRSGYAEVIKHALIGDVKLYHWLKEEVQTLADLRDEKLIHILTKAIPVKANIVAQDETEKGVRA
HLNFGHTLGHALEKELGYGNITHGDGVAVGMLFAIFLSEQVYKVNLAYEEMKQWFLKYGYPKMPSDLSVERLVGLMKQDK
KANAGTIHMVLMQEYGVVNVVSIPDETVHIALEAFQKDMVEK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=313, Percent_Identity=43.1309904153355, Blast_Score=234, Evalue=9e-63,
Organism=Saccharomyces cerevisiae, GI6320332, Length=372, Percent_Identity=32.7956989247312, Blast_Score=167, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 40263; Mature: 40132

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNIHIQTKSKEYDVYVGKESLSHLTTIVQNMQPSVSNIMIISDEAVASLHLQTVVDALQ
CCCEEEEECCCCEEEEECHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHH
IDQKVFSFVVPSGEKEKSFENFYAAHTSALENKLDRNSLIVALGGGMIGDLAGFVAASFM
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHH
RGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQPEAVVYHTPFLQSLPEKEWRS
HCCEEEEECHHHHHCCCCCCCEEEECCCCCCHHHCCCCCCCEEEEECHHHHHCCHHHHHC
GYAEVIKHALIGDVKLYHWLKEEVQTLADLRDEKLIHILTKAIPVKANIVAQDETEKGVR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCE
AHLNFGHTLGHALEKELGYGNITHGDGVAVGMLFAIFLSEQVYKVNLAYEEMKQWFLKYG
ECCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCHHEEEECHHHHHHHHHHHCC
YPKMPSDLSVERLVGLMKQDKKANAGTIHMVLMQEYGVVNVVSIPDETVHIALEAFQKDM
CCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEHHCCEEEEEECCCHHHHHHHHHHHHHH
VEK
CCC
>Mature Secondary Structure 
GNIHIQTKSKEYDVYVGKESLSHLTTIVQNMQPSVSNIMIISDEAVASLHLQTVVDALQ
CCEEEEECCCCEEEEECHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHH
IDQKVFSFVVPSGEKEKSFENFYAAHTSALENKLDRNSLIVALGGGMIGDLAGFVAASFM
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHH
RGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQPEAVVYHTPFLQSLPEKEWRS
HCCEEEEECHHHHHCCCCCCCEEEECCCCCCHHHCCCCCCCEEEEECHHHHHCCHHHHHC
GYAEVIKHALIGDVKLYHWLKEEVQTLADLRDEKLIHILTKAIPVKANIVAQDETEKGVR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCE
AHLNFGHTLGHALEKELGYGNITHGDGVAVGMLFAIFLSEQVYKVNLAYEEMKQWFLKYG
ECCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCHHEEEECHHHHHHHHHHHCC
YPKMPSDLSVERLVGLMKQDKKANAGTIHMVLMQEYGVVNVVSIPDETVHIALEAFQKDM
CCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEHHCCEEEEEECCCHHHHHHHHHHHHHH
VEK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA